The metabolic syndrome is frequent in children and adolescents with type 1 diabetes compared to healthy controls

Freja Barrett Mork; Jens Otto Broby Madsen; Kasper Ascanius Pilgaard; Andreas Kryger Jensen; Heidi Klakk; Jakob Tarp; Anna Bugge; Malene Heidemann; Gerrit Van Hall; Flemming Pociot; Niels Wedderkopp; Jesper Johannesen

doi:10.1111/pedi.13378

The metabolic syndrome is frequent in children and adolescents with type 1 diabetes compared to healthy controls

Freja Barrett Mork^*, Jens Otto Broby Madsen, Kasper Ascanius Pilgaard, Andreas Kryger Jensen, Heidi Klakk, Jakob Tarp, Anna Bugge, Malene Heidemann, Gerrit Van Hall, Flemming Pociot, Niels Wedderkopp, Jesper Johannesen

^*Corresponding author af dette arbejde

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

6 Citationer (Scopus)

26 Downloads (Pure)

Abstract

Objective There is a rise in overweight and obesity among children and adolescents with type 1 diabetes (T1D) in parallel with the rise in the metabolic syndrome (MetS) among children and adolescents. The aim of the study was to describe the prevalence and characteristics of MetS in children and adolescents with T1D compared to their healthy counterparts. Research Design and Methods The study includes two Danish cohorts; (i) the Copenhagen cross sectional cohort 2016 of 277 children and adolescents with T1D that attend the pediatric outpatient clinic at a large hospital in greater Copenhagen and (ii) the CHAMPS-study DK which is a population-based cohort study of Danish children and adolescents (control cohort). Participants were categorized to have MetS if at least two of the following criteria were met: (i) systolic and/or diastolic blood pressure >= 90th percentile, (ii) waist circumference >= 90th percentile, and (iii) triglyceride >= 90th percentile and/or HDL

Originalsprog	Engelsk
Tidsskrift	Pediatric Diabetes
Vol/bind	23
Udgave nummer	7
Sider (fra-til)	1064-1072
Antal sider	9
ISSN	1399-543X
DOI	https://doi.org/10.1111/pedi.13378
Status	Udgivet - 2022

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10.1111/pedi.13378

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title = "The metabolic syndrome is frequent in children and adolescents with type 1 diabetes compared to healthy controls",

abstract = "Objective There is a rise in overweight and obesity among children and adolescents with type 1 diabetes (T1D) in parallel with the rise in the metabolic syndrome (MetS) among children and adolescents. The aim of the study was to describe the prevalence and characteristics of MetS in children and adolescents with T1D compared to their healthy counterparts. Research Design and Methods The study includes two Danish cohorts; (i) the Copenhagen cross sectional cohort 2016 of 277 children and adolescents with T1D that attend the pediatric outpatient clinic at a large hospital in greater Copenhagen and (ii) the CHAMPS-study DK which is a population-based cohort study of Danish children and adolescents (control cohort). Participants were categorized to have MetS if at least two of the following criteria were met: (i) systolic and/or diastolic blood pressure >= 90th percentile, (ii) waist circumference >= 90th percentile, and (iii) triglyceride >= 90th percentile and/or HDL",

keywords = "adolescence, children, metabolic syndrome x, pediatrics, type 1 diabetes mellitus, ACCELERATOR HYPOTHESIS, CARDIOVASCULAR RISK, INSULIN-RESISTANCE, PUBERTAL CHANGES, BODY-MASS, PREVALENCE, CHILDHOOD, OBESITY, AGE, DEFINITIONS",

author = "Mork, {Freja Barrett} and Madsen, {Jens Otto Broby} and Pilgaard, {Kasper Ascanius} and Jensen, {Andreas Kryger} and Heidi Klakk and Jakob Tarp and Anna Bugge and Malene Heidemann and {Van Hall}, Gerrit and Flemming Pociot and Niels Wedderkopp and Jesper Johannesen",

year = "2022",

doi = "10.1111/pedi.13378",

language = "English",

volume = "23",

pages = "1064--1072",

journal = "Pediatric Diabetes",

issn = "1399-543X",

publisher = "Wiley-Blackwell",

number = "7",

}

TY - JOUR

T1 - The metabolic syndrome is frequent in children and adolescents with type 1 diabetes compared to healthy controls

AU - Mork, Freja Barrett

AU - Madsen, Jens Otto Broby

AU - Pilgaard, Kasper Ascanius

AU - Jensen, Andreas Kryger

AU - Klakk, Heidi

AU - Tarp, Jakob

AU - Bugge, Anna

AU - Heidemann, Malene

AU - Van Hall, Gerrit

AU - Pociot, Flemming

AU - Wedderkopp, Niels

AU - Johannesen, Jesper

PY - 2022

Y1 - 2022

N2 - Objective There is a rise in overweight and obesity among children and adolescents with type 1 diabetes (T1D) in parallel with the rise in the metabolic syndrome (MetS) among children and adolescents. The aim of the study was to describe the prevalence and characteristics of MetS in children and adolescents with T1D compared to their healthy counterparts. Research Design and Methods The study includes two Danish cohorts; (i) the Copenhagen cross sectional cohort 2016 of 277 children and adolescents with T1D that attend the pediatric outpatient clinic at a large hospital in greater Copenhagen and (ii) the CHAMPS-study DK which is a population-based cohort study of Danish children and adolescents (control cohort). Participants were categorized to have MetS if at least two of the following criteria were met: (i) systolic and/or diastolic blood pressure >= 90th percentile, (ii) waist circumference >= 90th percentile, and (iii) triglyceride >= 90th percentile and/or HDL

AB - Objective There is a rise in overweight and obesity among children and adolescents with type 1 diabetes (T1D) in parallel with the rise in the metabolic syndrome (MetS) among children and adolescents. The aim of the study was to describe the prevalence and characteristics of MetS in children and adolescents with T1D compared to their healthy counterparts. Research Design and Methods The study includes two Danish cohorts; (i) the Copenhagen cross sectional cohort 2016 of 277 children and adolescents with T1D that attend the pediatric outpatient clinic at a large hospital in greater Copenhagen and (ii) the CHAMPS-study DK which is a population-based cohort study of Danish children and adolescents (control cohort). Participants were categorized to have MetS if at least two of the following criteria were met: (i) systolic and/or diastolic blood pressure >= 90th percentile, (ii) waist circumference >= 90th percentile, and (iii) triglyceride >= 90th percentile and/or HDL

KW - adolescence

KW - children

KW - metabolic syndrome x

KW - pediatrics

KW - type 1 diabetes mellitus

KW - ACCELERATOR HYPOTHESIS

KW - CARDIOVASCULAR RISK

KW - INSULIN-RESISTANCE

KW - PUBERTAL CHANGES

KW - BODY-MASS

KW - PREVALENCE

KW - CHILDHOOD

KW - OBESITY

KW - AGE

KW - DEFINITIONS

U2 - 10.1111/pedi.13378

DO - 10.1111/pedi.13378

M3 - Journal article

C2 - 35678773

SN - 1399-543X

VL - 23

SP - 1064

EP - 1072

JO - Pediatric Diabetes

JF - Pediatric Diabetes

IS - 7

ER -