The microRNA molecular signature of atypic and common acquired melanocytic nevi: differential expression of miR-125b and let-7c

Line Marie Broksø Holst; Bogumil Kaczkowski; Martin Glud; Ewa Futoma-Kazmierczak; Lennart Jan Friis-Hansen; Robert Gniadecki

doi:10.1111/j.1600-0625.2010.01163.x

The microRNA molecular signature of atypic and common acquired melanocytic nevi: differential expression of miR-125b and let-7c

Line Marie Broksø Holst, Bogumil Kaczkowski, Martin Glud, Ewa Futoma-Kazmierczak, Lennart Jan Friis-Hansen, Robert Gniadecki

Ph.d.-studienævnet for Medicin

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

20 Citationer (Scopus)

Abstract

MicroRNAs (miRNAs) are small non-coding RNAs, which regulate gene expression through base pairing with mRNA and which are crucially involved in carcinogenesis (the so-called oncomiRs). We compared the miRNA signature between acquired melanocytic nevi showing clinical atypia (atypic nevi, AN) and common acquired nevi (common nevi, CN). We obtained miRNA profiles from 41 biopsies (22 AN and 19 CN) and showed that AN could be differentiated from CN on the basis of the expression of 36 miRNAs (false discovery rate

Originalsprog	Engelsk
Tidsskrift	Experimental Dermatology
Vol/bind	20
Udgave nummer	3
Sider (fra-til)	278-80
Antal sider	3
ISSN	0906-6705
DOI	https://doi.org/10.1111/j.1600-0625.2010.01163.x
Status	Udgivet - 2011

Adgang til dokumentet

10.1111/j.1600-0625.2010.01163.x

Biblioteksadgang?

Tjek tilgængelighed hos det Kgl. Bibliotek

Citationsformater

@article{48380e32077347e082bc8cee34539cc0,

title = "The microRNA molecular signature of atypic and common acquired melanocytic nevi: differential expression of miR-125b and let-7c",

abstract = "MicroRNAs (miRNAs) are small non-coding RNAs, which regulate gene expression through base pairing with mRNA and which are crucially involved in carcinogenesis (the so-called oncomiRs). We compared the miRNA signature between acquired melanocytic nevi showing clinical atypia (atypic nevi, AN) and common acquired nevi (common nevi, CN). We obtained miRNA profiles from 41 biopsies (22 AN and 19 CN) and showed that AN could be differentiated from CN on the basis of the expression of 36 miRNAs (false discovery rate",

author = "Holst, {Line Marie Broks{\o}} and Bogumil Kaczkowski and Martin Glud and Ewa Futoma-Kazmierczak and Friis-Hansen, {Lennart Jan} and Robert Gniadecki",

note = "{\textcopyright} 2010 John Wiley & Sons A/S.",

year = "2011",

doi = "10.1111/j.1600-0625.2010.01163.x",

language = "English",

volume = "20",

pages = "278--80",

journal = "Experimental Dermatology",

issn = "0906-6705",

publisher = "Wiley-Blackwell",

number = "3",

}

TY - JOUR

T1 - The microRNA molecular signature of atypic and common acquired melanocytic nevi: differential expression of miR-125b and let-7c

AU - Holst, Line Marie Broksø

AU - Kaczkowski, Bogumil

AU - Glud, Martin

AU - Futoma-Kazmierczak, Ewa

AU - Friis-Hansen, Lennart Jan

AU - Gniadecki, Robert

PY - 2011

Y1 - 2011

N2 - MicroRNAs (miRNAs) are small non-coding RNAs, which regulate gene expression through base pairing with mRNA and which are crucially involved in carcinogenesis (the so-called oncomiRs). We compared the miRNA signature between acquired melanocytic nevi showing clinical atypia (atypic nevi, AN) and common acquired nevi (common nevi, CN). We obtained miRNA profiles from 41 biopsies (22 AN and 19 CN) and showed that AN could be differentiated from CN on the basis of the expression of 36 miRNAs (false discovery rate

AB - MicroRNAs (miRNAs) are small non-coding RNAs, which regulate gene expression through base pairing with mRNA and which are crucially involved in carcinogenesis (the so-called oncomiRs). We compared the miRNA signature between acquired melanocytic nevi showing clinical atypia (atypic nevi, AN) and common acquired nevi (common nevi, CN). We obtained miRNA profiles from 41 biopsies (22 AN and 19 CN) and showed that AN could be differentiated from CN on the basis of the expression of 36 miRNAs (false discovery rate

U2 - 10.1111/j.1600-0625.2010.01163.x

DO - 10.1111/j.1600-0625.2010.01163.x

M3 - Journal article

SN - 0906-6705

VL - 20

SP - 278

EP - 280

JO - Experimental Dermatology

JF - Experimental Dermatology

IS - 3

ER -