The OMERACT MRI in enthesitis initiative: Definitions of key pathologies, suggested MRI sequences, and a novel heel enthesitis scoring system

Ashish J. Mathew; Simon Krabbe; Iris Eshed; Frédérique Gandjbakhch; Paul Bird; Susanne J. Pedersen; Maria S. Stoenoiu; Violaine Foltz; Daniel Glinatsi; Robert G. Lambert; Kay Geert A. Hermann; Walter P. Maksymowych; Ida K. Haugen; Jacob L. Jaremko; René P. Poggenborg; Joel Paschke; Jean Denis Laredo; Philippe Carron; Philip G. Conaghan; Mikkel Østergaard

doi:10.3899/jrheum.181093

The OMERACT MRI in enthesitis initiative: Definitions of key pathologies, suggested MRI sequences, and a novel heel enthesitis scoring system

Ashish J. Mathew, Simon Krabbe, Iris Eshed, Frédérique Gandjbakhch, Paul Bird, Susanne J. Pedersen, Maria S. Stoenoiu, Violaine Foltz, Daniel Glinatsi, Robert G. Lambert, Kay Geert A. Hermann, Walter P. Maksymowych, Ida K. Haugen, Jacob L. Jaremko, René P. Poggenborg, Joel Paschke, Jean Denis Laredo, Philippe Carron, Philip G. Conaghan, Mikkel Østergaard^*

^*Corresponding author af dette arbejde

Publikation: Bidrag til tidsskrift › Review › peer review

48 Citationer (Scopus)

12 Downloads (Pure)

Abstract

Objective. To develop and validate an enthesitis magnetic resonance imaging (MRI) scoring system for spondyloarthritis/psoriatic arthritis, using the heel as model. Methods. Consensus definitions of key pathologies and 3 heel enthesitis multireader scoring exercises were done, separated by discussion, training, and calibration. Results. Definitions for bone and soft tissue pathologies were agreed. In the final exercise, median pairwise single-measures intraclass correlation coefficients (ICC; patient-level) for entheseal inflammation status/change scores were 0.83/0.82 for all readers. For radiologists and selected rheumatologists, ICC were 0.91/0.84 and quadratic-weighted κ (lesion-level) 0.57-0.91/0.45-0.81. Conclusion. The proposed definitions and Heel Enthesitis Scoring System (HEMRIS) are reliable among trained readers and promising for clinical trials.

Originalsprog	Engelsk
Tidsskrift	Journal of Rheumatology
Vol/bind	46
Udgave nummer	9
Sider (fra-til)	1232-1238
Antal sider	7
ISSN	0315-162X
DOI	https://doi.org/10.3899/jrheum.181093
Status	Udgivet - 2019

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10.3899/jrheum.181093

The OMERACT MRI in Enthesitis Initiative_Definitions of Key pathologies, suggested MRI sequences, and a novel heel enthesitis scoring systemAccepteret manuskript, 228 KB

Citationsformater

Mathew, A. J., Krabbe, S., Eshed, I., Gandjbakhch, F., Bird, P., Pedersen, S. J., Stoenoiu, M. S., Foltz, V., Glinatsi, D., Lambert, R. G., Hermann, K. G. A., Maksymowych, W. P., Haugen, I. K., Jaremko, J. L., Poggenborg, R. P., Paschke, J., Laredo, J. D., Carron, P., Conaghan, P. G., & Østergaard, M. (2019). The OMERACT MRI in enthesitis initiative: Definitions of key pathologies, suggested MRI sequences, and a novel heel enthesitis scoring system. Journal of Rheumatology, 46(9), 1232-1238. https://doi.org/10.3899/jrheum.181093

Mathew, AJ, Krabbe, S, Eshed, I, Gandjbakhch, F, Bird, P, Pedersen, SJ, Stoenoiu, MS, Foltz, V, Glinatsi, D, Lambert, RG, Hermann, KGA, Maksymowych, WP, Haugen, IK, Jaremko, JL, Poggenborg, RP, Paschke, J, Laredo, JD, Carron, P, Conaghan, PG & Østergaard, M 2019, 'The OMERACT MRI in enthesitis initiative: Definitions of key pathologies, suggested MRI sequences, and a novel heel enthesitis scoring system', Journal of Rheumatology, bind 46, nr. 9, s. 1232-1238. https://doi.org/10.3899/jrheum.181093

@article{7d85657f2a0041fc971540d64c46fdc8,

title = "The OMERACT MRI in enthesitis initiative: Definitions of key pathologies, suggested MRI sequences, and a novel heel enthesitis scoring system",

abstract = "Objective. To develop and validate an enthesitis magnetic resonance imaging (MRI) scoring system for spondyloarthritis/psoriatic arthritis, using the heel as model. Methods. Consensus definitions of key pathologies and 3 heel enthesitis multireader scoring exercises were done, separated by discussion, training, and calibration. Results. Definitions for bone and soft tissue pathologies were agreed. In the final exercise, median pairwise single-measures intraclass correlation coefficients (ICC; patient-level) for entheseal inflammation status/change scores were 0.83/0.82 for all readers. For radiologists and selected rheumatologists, ICC were 0.91/0.84 and quadratic-weighted κ (lesion-level) 0.57-0.91/0.45-0.81. Conclusion. The proposed definitions and Heel Enthesitis Scoring System (HEMRIS) are reliable among trained readers and promising for clinical trials.",

keywords = "Enthesopathy, Magnetic resonance imaging, Omeract, Psoriatic arthritis, Spondyloarthropathy",

author = "Mathew, {Ashish J.} and Simon Krabbe and Iris Eshed and Fr{\'e}d{\'e}rique Gandjbakhch and Paul Bird and Pedersen, {Susanne J.} and Stoenoiu, {Maria S.} and Violaine Foltz and Daniel Glinatsi and Lambert, {Robert G.} and Hermann, {Kay Geert A.} and Maksymowych, {Walter P.} and Haugen, {Ida K.} and Jaremko, {Jacob L.} and Poggenborg, {Ren{\'e} P.} and Joel Paschke and Laredo, {Jean Denis} and Philippe Carron and Conaghan, {Philip G.} and Mikkel {\O}stergaard",

year = "2019",

doi = "10.3899/jrheum.181093",

language = "English",

volume = "46",

pages = "1232--1238",

journal = "Journal of Rheumatology",

issn = "0315-162X",

publisher = "Journal of Rheumatology Publishing Co. Ltd.",

number = "9",

}

TY - JOUR

T1 - The OMERACT MRI in enthesitis initiative

T2 - Definitions of key pathologies, suggested MRI sequences, and a novel heel enthesitis scoring system

AU - Mathew, Ashish J.

AU - Krabbe, Simon

AU - Eshed, Iris

AU - Gandjbakhch, Frédérique

AU - Bird, Paul

AU - Pedersen, Susanne J.

AU - Stoenoiu, Maria S.

AU - Foltz, Violaine

AU - Glinatsi, Daniel

AU - Lambert, Robert G.

AU - Hermann, Kay Geert A.

AU - Maksymowych, Walter P.

AU - Haugen, Ida K.

AU - Jaremko, Jacob L.

AU - Poggenborg, René P.

AU - Paschke, Joel

AU - Laredo, Jean Denis

AU - Carron, Philippe

AU - Conaghan, Philip G.

AU - Østergaard, Mikkel

PY - 2019

Y1 - 2019

N2 - Objective. To develop and validate an enthesitis magnetic resonance imaging (MRI) scoring system for spondyloarthritis/psoriatic arthritis, using the heel as model. Methods. Consensus definitions of key pathologies and 3 heel enthesitis multireader scoring exercises were done, separated by discussion, training, and calibration. Results. Definitions for bone and soft tissue pathologies were agreed. In the final exercise, median pairwise single-measures intraclass correlation coefficients (ICC; patient-level) for entheseal inflammation status/change scores were 0.83/0.82 for all readers. For radiologists and selected rheumatologists, ICC were 0.91/0.84 and quadratic-weighted κ (lesion-level) 0.57-0.91/0.45-0.81. Conclusion. The proposed definitions and Heel Enthesitis Scoring System (HEMRIS) are reliable among trained readers and promising for clinical trials.

AB - Objective. To develop and validate an enthesitis magnetic resonance imaging (MRI) scoring system for spondyloarthritis/psoriatic arthritis, using the heel as model. Methods. Consensus definitions of key pathologies and 3 heel enthesitis multireader scoring exercises were done, separated by discussion, training, and calibration. Results. Definitions for bone and soft tissue pathologies were agreed. In the final exercise, median pairwise single-measures intraclass correlation coefficients (ICC; patient-level) for entheseal inflammation status/change scores were 0.83/0.82 for all readers. For radiologists and selected rheumatologists, ICC were 0.91/0.84 and quadratic-weighted κ (lesion-level) 0.57-0.91/0.45-0.81. Conclusion. The proposed definitions and Heel Enthesitis Scoring System (HEMRIS) are reliable among trained readers and promising for clinical trials.

KW - Enthesopathy

KW - Magnetic resonance imaging

KW - Omeract

KW - Psoriatic arthritis

KW - Spondyloarthropathy

U2 - 10.3899/jrheum.181093

DO - 10.3899/jrheum.181093

M3 - Review

C2 - 30709961

AN - SCOPUS:85071787224

SN - 0315-162X

VL - 46

SP - 1232

EP - 1238

JO - Journal of Rheumatology

JF - Journal of Rheumatology

IS - 9

ER -