The P9 pocket of HLA-DQ2 (non-Aspbeta57) has no particular preference for negatively charged anchor residues found in other type 1 diabetes-predisposing non-Aspbeta57 MHC class II molecules

H Quarsten, G Paulsen, B H Johansen, C J Thorpe, A Holm, S Buus, L M Sollid

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

    30 Citationer (Scopus)

    Abstract

    Udgivelsesdato: 1998-Aug
    OriginalsprogEngelsk
    TidsskriftInternational Immunology
    Vol/bind10
    Udgave nummer8
    Sider (fra-til)1229-36
    Antal sider7
    ISSN0953-8178
    StatusUdgivet - 1998

    Bibliografisk note

    Keywords: Alanine; Alleles; Aspartic Acid; B-Lymphocytes; Binding Sites; Cell Line; Computer Simulation; Diabetes Mellitus, Type 1; Genes, MHC Class II; Genetic Predisposition to Disease; HLA-DQ Antigens; Histocompatibility Antigens Class II; Humans; Models, Molecular; Mutagenesis, Site-Directed; Peptide Library; Peptides; Protein Engineering; Static Electricity; Transfection

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