The Permeation of Acamprosate Is Predominantly Caused by Paracellular Diffusion across Caco-2 Cell Monolayers: A Paracellular Modeling Approach

Irina E. Antonescu; Karina F. Rasmussen; Sibylle Neuhoff; Xavier Frette; Maria Karlgren; Christel A. S. Bergstrom; Carsten Uhd Nielsen; Bente Steffansen

doi:10.1021/acs.molpharmaceut.9b00733

The Permeation of Acamprosate Is Predominantly Caused by Paracellular Diffusion across Caco-2 Cell Monolayers: A Paracellular Modeling Approach

Irina E. Antonescu, Karina F. Rasmussen, Sibylle Neuhoff, Xavier Frette, Maria Karlgren, Christel A. S. Bergstrom, Carsten Uhd Nielsen, Bente Steffansen

Institut for Farmaci

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

10 Citationer (Scopus)

Originalsprog	Engelsk
Tidsskrift	Molecular Pharmaceutics
Vol/bind	16
Udgave nummer	11
Sider (fra-til)	4636-4650
ISSN	1543-8384
DOI	https://doi.org/10.1021/acs.molpharmaceut.9b00733
Status	Udgivet - 2019

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10.1021/acs.molpharmaceut.9b00733

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Citationsformater

Antonescu, I. E., Rasmussen, K. F., Neuhoff, S., Frette, X., Karlgren, M., Bergstrom, C. A. S., Nielsen, C. U., & Steffansen, B. (2019). The Permeation of Acamprosate Is Predominantly Caused by Paracellular Diffusion across Caco-2 Cell Monolayers: A Paracellular Modeling Approach. Molecular Pharmaceutics, 16(11), 4636-4650. https://doi.org/10.1021/acs.molpharmaceut.9b00733

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title = "The Permeation of Acamprosate Is Predominantly Caused by Paracellular Diffusion across Caco-2 Cell Monolayers: A Paracellular Modeling Approach",

keywords = "paracellular modeling, acamprosate, permeability-limited absorption, Caco-2, paracellular permeability, transcellular permeability, permeability modeling",

author = "Antonescu, {Irina E.} and Rasmussen, {Karina F.} and Sibylle Neuhoff and Xavier Frette and Maria Karlgren and Bergstrom, {Christel A. S.} and Nielsen, {Carsten Uhd} and Bente Steffansen",

year = "2019",

doi = "10.1021/acs.molpharmaceut.9b00733",

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T1 - The Permeation of Acamprosate Is Predominantly Caused by Paracellular Diffusion across Caco-2 Cell Monolayers: A Paracellular Modeling Approach

AU - Antonescu, Irina E.

AU - Rasmussen, Karina F.

AU - Neuhoff, Sibylle

AU - Frette, Xavier

AU - Karlgren, Maria

AU - Bergstrom, Christel A. S.

AU - Nielsen, Carsten Uhd

AU - Steffansen, Bente

PY - 2019

Y1 - 2019

KW - paracellular modeling

KW - acamprosate

KW - permeability-limited absorption

KW - Caco-2

KW - paracellular permeability

KW - transcellular permeability

KW - permeability modeling

U2 - 10.1021/acs.molpharmaceut.9b00733

DO - 10.1021/acs.molpharmaceut.9b00733

M3 - Journal article

C2 - 31560549

SN - 1543-8384

VL - 16

SP - 4636

EP - 4650

JO - Molecular Pharmaceutics

JF - Molecular Pharmaceutics

IS - 11

ER -