Threshold electrical stimulation (TES) in ambulant children with CP: a randomized double-blind placebo-controlled clinical trial

Christine í Dali; Flemming Juul Hansen; Søren Anker Pedersen; Liselotte Skov; Jørgen Hilden; Inge Bjørnskov; Charlotte Strandberg; Jette Christensen; Ulla Haugsted; Grethe Herbst; Ulla Lyskjaer

Threshold electrical stimulation (TES) in ambulant children with CP: a randomized double-blind placebo-controlled clinical trial

Christine í Dali, Flemming Juul Hansen, Søren Anker Pedersen, Liselotte Skov, Jørgen Hilden, Inge Bjørnskov, Charlotte Strandberg, Jette Christensen, Ulla Haugsted, Grethe Herbst, Ulla Lyskjaer

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

32 Citationer (Scopus)

Abstract

Udgivelsesdato: 2002-Jun

Originalsprog	Engelsk
Tidsskrift	Developmental Medicine and Child Neurology
Vol/bind	44
Udgave nummer	6
Sider (fra-til)	364-369
Antal sider	5
ISSN	0012-1622
Status	Udgivet - 2002

Bibliografisk note

Keywords: Adolescent; Cerebral Palsy; Child; Child, Preschool; Double-Blind Method; Electric Stimulation Therapy; Female; Humans; Male; Motor Skills Disorders; Muscle, Skeletal; Placebos; Severity of Illness Index; Treatment Outcome

Citationsformater

Threshold electrical stimulation (TES) in ambulant children with CP: a randomized double-blind placebo-controlled clinical trial. / Dali, Christine í; Hansen, Flemming Juul; Pedersen, Søren Anker; Skov, Liselotte; Hilden, Jørgen; Bjørnskov, Inge; Strandberg, Charlotte; Christensen, Jette; Haugsted, Ulla; Herbst, Grethe; Lyskjaer, Ulla.

I: Developmental Medicine and Child Neurology, Bind 44, Nr. 6, 2002, s. 364-369.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

Dali, Christine í ; Hansen, Flemming Juul ; Pedersen, Søren Anker ; Skov, Liselotte ; Hilden, Jørgen ; Bjørnskov, Inge ; Strandberg, Charlotte ; Christensen, Jette ; Haugsted, Ulla ; Herbst, Grethe ; Lyskjaer, Ulla. / Threshold electrical stimulation (TES) in ambulant children with CP: a randomized double-blind placebo-controlled clinical trial. I: Developmental Medicine and Child Neurology. 2002 ; Bind 44, Nr. 6. s. 364-369.

@article{a8712bd074c511dbbee902004c4f4f50,

title = "Threshold electrical stimulation (TES) in ambulant children with CP: a randomized double-blind placebo-controlled clinical trial",

abstract = "A randomized double-blind placebo-controlled clinical trial was carried out to determine whether a group of stable children with cerebral palsy (36 males, 21 females; mean age 10 years 11 months, range 5 to 18 years) would improve their motor skills after 12 months of threshold electrical stimulation (TES). Two thirds received active and one third received inactive stimulators. For the primary outcome we constructed a set of plausible motor function tests and studied the change in summary indices of the performance measurements. Tests were videotaped and assessed blindly to record qualitative changes that might not be reflected in performance measurements. We also judged range of motion, degree of spasticity, and muscle growth measured by CT. Fifty seven of 82 outpatients who were able to walk at least with a walker, completed all 12 months of treatment (hemiplegia n=25, diplegia n=32). There was no significant difference between active and placebo treatment in any of the tested groups, nor combined. Visual and subjective assessments favoured TES (ns), whereas objective indices showed the opposite trend. We conclude that TES in these patients did not have any significant clinical effect during the test period.",

author = "Dali, {Christine {\'i}} and Hansen, {Flemming Juul} and Pedersen, {S{\o}ren Anker} and Liselotte Skov and J{\o}rgen Hilden and Inge Bj{\o}rnskov and Charlotte Strandberg and Jette Christensen and Ulla Haugsted and Grethe Herbst and Ulla Lyskjaer",

note = "Keywords: Adolescent; Cerebral Palsy; Child; Child, Preschool; Double-Blind Method; Electric Stimulation Therapy; Female; Humans; Male; Motor Skills Disorders; Muscle, Skeletal; Placebos; Severity of Illness Index; Treatment Outcome",

year = "2002",

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T1 - Threshold electrical stimulation (TES) in ambulant children with CP: a randomized double-blind placebo-controlled clinical trial

AU - Dali, Christine í

AU - Hansen, Flemming Juul

AU - Pedersen, Søren Anker

AU - Skov, Liselotte

AU - Hilden, Jørgen

AU - Bjørnskov, Inge

AU - Strandberg, Charlotte

AU - Christensen, Jette

AU - Haugsted, Ulla

AU - Herbst, Grethe

AU - Lyskjaer, Ulla

N1 - Keywords: Adolescent; Cerebral Palsy; Child; Child, Preschool; Double-Blind Method; Electric Stimulation Therapy; Female; Humans; Male; Motor Skills Disorders; Muscle, Skeletal; Placebos; Severity of Illness Index; Treatment Outcome

PY - 2002

Y1 - 2002

N2 - A randomized double-blind placebo-controlled clinical trial was carried out to determine whether a group of stable children with cerebral palsy (36 males, 21 females; mean age 10 years 11 months, range 5 to 18 years) would improve their motor skills after 12 months of threshold electrical stimulation (TES). Two thirds received active and one third received inactive stimulators. For the primary outcome we constructed a set of plausible motor function tests and studied the change in summary indices of the performance measurements. Tests were videotaped and assessed blindly to record qualitative changes that might not be reflected in performance measurements. We also judged range of motion, degree of spasticity, and muscle growth measured by CT. Fifty seven of 82 outpatients who were able to walk at least with a walker, completed all 12 months of treatment (hemiplegia n=25, diplegia n=32). There was no significant difference between active and placebo treatment in any of the tested groups, nor combined. Visual and subjective assessments favoured TES (ns), whereas objective indices showed the opposite trend. We conclude that TES in these patients did not have any significant clinical effect during the test period.

AB - A randomized double-blind placebo-controlled clinical trial was carried out to determine whether a group of stable children with cerebral palsy (36 males, 21 females; mean age 10 years 11 months, range 5 to 18 years) would improve their motor skills after 12 months of threshold electrical stimulation (TES). Two thirds received active and one third received inactive stimulators. For the primary outcome we constructed a set of plausible motor function tests and studied the change in summary indices of the performance measurements. Tests were videotaped and assessed blindly to record qualitative changes that might not be reflected in performance measurements. We also judged range of motion, degree of spasticity, and muscle growth measured by CT. Fifty seven of 82 outpatients who were able to walk at least with a walker, completed all 12 months of treatment (hemiplegia n=25, diplegia n=32). There was no significant difference between active and placebo treatment in any of the tested groups, nor combined. Visual and subjective assessments favoured TES (ns), whereas objective indices showed the opposite trend. We conclude that TES in these patients did not have any significant clinical effect during the test period.

M3 - Journal article

C2 - 12088304

VL - 44

SP - 364

EP - 369

JO - Developmental medicine and child neurology. Supplement

JF - Developmental medicine and child neurology. Supplement

SN - 0419-0238

IS - 6

ER -