Transcatheter Aortic Valve Replacement: Role of Multimodality Imaging in Common and Complex Clinical Scenarios

Jeroen J. Bax; Victoria Delgado; Rebecca T. Hahn; Jonathon Leipsic; James K. Min; Paul Grayburn; Lars Sondergaard; Sung Han Yoon; Stephan Windecker

doi:10.1016/j.jcmg.2018.10.037

Transcatheter Aortic Valve Replacement: Role of Multimodality Imaging in Common and Complex Clinical Scenarios

Jeroen J. Bax^*
, Victoria Delgado
, Rebecca T. Hahn
, Jonathon Leipsic
, James K. Min
, Paul Grayburn
, Lars Sondergaard
, Sung Han Yoon
, Stephan Windecker

^*Corresponding author af dette arbejde

Publikation: Bidrag til tidsskrift › Review › peer review

Abstract

Transcatheter aortic valve replacement (TAVR) is an established therapy for patients with symptomatic severe aortic stenosis. Technological advances and the learning curve have resulted in better procedural results in terms of hemodynamic valve performance and intermediate-term clinical outcomes. The integration of anatomical and functional information provided by multimodality imaging has improved size selection of TAVR prostheses, permitted better patient selection, and provided new insights in the performance of the TAVR prostheses at follow-up. Furthermore, the field of TAVR continues to develop and expand the technique to younger patients with lower risk on the one hand, and more complex clinical scenarios, on the other hand, such as degenerated aortic bioprostheses, bicuspid aortic valves, or pure native aortic regurgitation. The present review article summarizes how multimodality imaging can be integrated in TAVR in clinical (sometimes complex) scenarios that have not been included in the landmark randomized clinical trials.

Originalsprog	Engelsk
Tidsskrift	JACC: Cardiovascular Imaging
Vol/bind	13
Udgave nummer	Issue 1. Part 1
Sider (fra-til)	124-139
ISSN	1936-878X
DOI	https://doi.org/10.1016/j.jcmg.2018.10.037
Status	Udgivet - jan. 2020

Finansiering

The Department of Cardiology, Leiden University Medical Center has received unrestricted research grants from Biotronik, Medtronic, Boston Scientific, GE Healthcare, and Edwards Lifesciences. Dr. Bax has received speaker fees from Abbott Vascular and Boehringer Ingelheim. Dr. Delgado has received speaker fees from Abbott Vascular. Dr. Leipsic has received institutional support through core laboratory services for Edwards Lifesciences, Medtronic, Abbott, and Neovasc; and serves as a consultant for Circle CVI and Heartflow. Dr. Windecker has received research and educational grants to the institution from Abbott, Amgen, Bayer, Bristol-Myers Squibb, Biotronik, Boston Scientific, CSL, Edwards, Medtronic, Sinomed, and Polares. Dr. Hahn has received speaker fees from Boston Scientific Corporation and Baylis Medical; consulting for Abbott Structural, Edwards Lifesciences, Gore&Associates, Medtronic, Navigate, Philips Healthcare, and Siemens Healthcare; non-financial support from 3mensio and GE Healthcare; is Chief Scientific Officer for the Echocardiography Core Laboratory at the Cardiovascular Research Foundation for multiple industry-sponsored trials, for which she receives no direct industry compensation. Dr. Sondergaard has received consultant fees and institutional research grants from Abbott, Boston Scientific, Edwards Lifesciences, and Medtronic. Dr. Min is on the Scientific Advisory Board of Arineta; has ownership in MDDX; and has a research agreement with GE Healthcare. Dr. Grayburn has received research grants Boston Scientific and under Core Lab contracts, Valtech Cardio is now Edwards Lifesciences.

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Citationsformater

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title = "Transcatheter Aortic Valve Replacement: Role of Multimodality Imaging in Common and Complex Clinical Scenarios",

abstract = "Transcatheter aortic valve replacement (TAVR) is an established therapy for patients with symptomatic severe aortic stenosis. Technological advances and the learning curve have resulted in better procedural results in terms of hemodynamic valve performance and intermediate-term clinical outcomes. The integration of anatomical and functional information provided by multimodality imaging has improved size selection of TAVR prostheses, permitted better patient selection, and provided new insights in the performance of the TAVR prostheses at follow-up. Furthermore, the field of TAVR continues to develop and expand the technique to younger patients with lower risk on the one hand, and more complex clinical scenarios, on the other hand, such as degenerated aortic bioprostheses, bicuspid aortic valves, or pure native aortic regurgitation. The present review article summarizes how multimodality imaging can be integrated in TAVR in clinical (sometimes complex) scenarios that have not been included in the landmark randomized clinical trials.",

keywords = "aortic regurgitation, bicuspid aortic valve, echocardiography, multi-detector row computed tomography, transcatheter aortic valve replacement",

author = "Bax, \{Jeroen J.\} and Victoria Delgado and Hahn, \{Rebecca T.\} and Jonathon Leipsic and Min, \{James K.\} and Paul Grayburn and Lars Sondergaard and Yoon, \{Sung Han\} and Stephan Windecker",

year = "2020",

month = jan,

doi = "10.1016/j.jcmg.2018.10.037",

language = "English",

volume = "13",

pages = "124--139",

journal = "JACC: Cardiovascular Imaging",

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T2 - Role of Multimodality Imaging in Common and Complex Clinical Scenarios

AU - Bax, Jeroen J.

AU - Delgado, Victoria

AU - Hahn, Rebecca T.

AU - Leipsic, Jonathon

AU - Min, James K.

AU - Grayburn, Paul

AU - Sondergaard, Lars

AU - Yoon, Sung Han

AU - Windecker, Stephan

PY - 2020/1

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N2 - Transcatheter aortic valve replacement (TAVR) is an established therapy for patients with symptomatic severe aortic stenosis. Technological advances and the learning curve have resulted in better procedural results in terms of hemodynamic valve performance and intermediate-term clinical outcomes. The integration of anatomical and functional information provided by multimodality imaging has improved size selection of TAVR prostheses, permitted better patient selection, and provided new insights in the performance of the TAVR prostheses at follow-up. Furthermore, the field of TAVR continues to develop and expand the technique to younger patients with lower risk on the one hand, and more complex clinical scenarios, on the other hand, such as degenerated aortic bioprostheses, bicuspid aortic valves, or pure native aortic regurgitation. The present review article summarizes how multimodality imaging can be integrated in TAVR in clinical (sometimes complex) scenarios that have not been included in the landmark randomized clinical trials.

AB - Transcatheter aortic valve replacement (TAVR) is an established therapy for patients with symptomatic severe aortic stenosis. Technological advances and the learning curve have resulted in better procedural results in terms of hemodynamic valve performance and intermediate-term clinical outcomes. The integration of anatomical and functional information provided by multimodality imaging has improved size selection of TAVR prostheses, permitted better patient selection, and provided new insights in the performance of the TAVR prostheses at follow-up. Furthermore, the field of TAVR continues to develop and expand the technique to younger patients with lower risk on the one hand, and more complex clinical scenarios, on the other hand, such as degenerated aortic bioprostheses, bicuspid aortic valves, or pure native aortic regurgitation. The present review article summarizes how multimodality imaging can be integrated in TAVR in clinical (sometimes complex) scenarios that have not been included in the landmark randomized clinical trials.

KW - aortic regurgitation

KW - bicuspid aortic valve

KW - echocardiography

KW - multi-detector row computed tomography

KW - transcatheter aortic valve replacement

U2 - 10.1016/j.jcmg.2018.10.037

DO - 10.1016/j.jcmg.2018.10.037

M3 - Review

C2 - 31103575

AN - SCOPUS:85076855817

SN - 1936-878X

VL - 13

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EP - 139

JO - JACC: Cardiovascular Imaging

JF - JACC: Cardiovascular Imaging

IS - Issue 1. Part 1

ER -