Treatment influencing down-staging in EORTC Melanoma Group sentinel node histological protocol compared with complete step-sectioning: a national multicentre study

Rikke Riber-Hansen, Nina Hastrup, Ole Clemmensen, Nille Behrendt, Siri Klausen, Mette Ramsing, Eva Spaun, Stephen Jacques Hamilton-Dutoit, Torben Steiniche

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

    17 Citationer (Scopus)

    Abstract

    Metastasis size in melanoma sentinel lymph nodes (SLNs) is an emerging prognostic factor. Two European melanoma treatment trials include SLN metastasis diameters as inclusion criteria. Whilst diameter estimates are sensitive to the number of sections examined, the level of this bias is largely unknown. We performed a prospective multicentre study to compare the European Organisation for Research and Treatment of Cancer (EORTC) recommended protocol with a protocol of complete step-sectioning.
    OriginalsprogEngelsk
    TidsskriftEuropean Journal of Cancer
    Vol/bind48
    Udgave nummer3
    Sider (fra-til)347-52
    Antal sider6
    ISSN0959-8049
    DOI
    StatusUdgivet - 2012

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