TY - JOUR
T1 - Treatment influencing down-staging in EORTC Melanoma Group sentinel node histological protocol compared with complete step-sectioning
T2 - a national multicentre study
AU - Riber-Hansen, Rikke
AU - Hastrup, Nina
AU - Clemmensen, Ole
AU - Behrendt, Nille
AU - Klausen, Siri
AU - Ramsing, Mette
AU - Spaun, Eva
AU - Hamilton-Dutoit, Stephen Jacques
AU - Steiniche, Torben
N1 - Copyright © 2011 Elsevier Ltd. All rights reserved.
PY - 2012
Y1 - 2012
N2 - Metastasis size in melanoma sentinel lymph nodes (SLNs) is an emerging prognostic factor. Two European melanoma treatment trials include SLN metastasis diameters as inclusion criteria. Whilst diameter estimates are sensitive to the number of sections examined, the level of this bias is largely unknown. We performed a prospective multicentre study to compare the European Organisation for Research and Treatment of Cancer (EORTC) recommended protocol with a protocol of complete step-sectioning.
AB - Metastasis size in melanoma sentinel lymph nodes (SLNs) is an emerging prognostic factor. Two European melanoma treatment trials include SLN metastasis diameters as inclusion criteria. Whilst diameter estimates are sensitive to the number of sections examined, the level of this bias is largely unknown. We performed a prospective multicentre study to compare the European Organisation for Research and Treatment of Cancer (EORTC) recommended protocol with a protocol of complete step-sectioning.
U2 - 10.1016/j.ejca.2011.08.019
DO - 10.1016/j.ejca.2011.08.019
M3 - Journal article
C2 - 22023888
SN - 0959-8049
VL - 48
SP - 347
EP - 352
JO - European Journal of Cancer
JF - European Journal of Cancer
IS - 3
ER -