Treatment of knee osteoarthritis with pulsed electromagnetic fields: a randomized, double-blind, placebo-controlled study

G Thamsborg; A Florescu; P Oturai; E Fallentin; K Tritsaris; S Dissing

doi:10.1016/j.joca.2005.02.012

Treatment of knee osteoarthritis with pulsed electromagnetic fields: a randomized, double-blind, placebo-controlled study

G Thamsborg, A Florescu, P Oturai, E Fallentin, K Tritsaris, S Dissing

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

103 Citationer (Scopus)

Abstract

Udgivelsesdato: 2005-Jul

Originalsprog	Engelsk
Tidsskrift	Osteoarthritis and Cartilage
Vol/bind	13
Udgave nummer	7
Sider (fra-til)	575-81
Antal sider	6
ISSN	1063-4584
DOI	https://doi.org/10.1016/j.joca.2005.02.012
Status	Udgivet - 2005

Bibliografisk note

Keywords: Activities of Daily Living; Double-Blind Method; Electromagnetic Fields; Female; Humans; Male; Middle Aged; Movement Disorders; Osteoarthritis, Knee; Pain; Physical Examination; Questionnaires

Adgang til dokumentet

10.1016/j.joca.2005.02.012

Citationsformater

@article{29d7e53071ce11de8bc9000ea68e967b,

title = "Treatment of knee osteoarthritis with pulsed electromagnetic fields: a randomized, double-blind, placebo-controlled study",

abstract = "OBJECTIVE: The investigation aimed at determining the effectiveness of pulsed electromagnetic fields (PEMF) in the treatment of osteoarthritis (OA) of the knee by conducting a randomized, double-blind, placebo-controlled clinical trial. DESIGN: The trial consisted of 2h daily treatment 5 days per week for 6 weeks in 83 patients with knee OA. Patient evaluations were done at baseline and after 2 and 6 weeks of treatment. A follow-up evaluation was done 6 weeks after treatment. Activities of daily living (ADL), pain and stiffness were evaluated using the Western Ontario and McMaster Universities (WOMAC) questionnaire. RESULTS: Within group analysis revealed a significant improvement in ADL, stiffness and pain in the PEMF-treated group at all evaluations. In the control group there was no effect on ADL after 2 weeks and a weak significance was seen after 6 and 12 weeks. Significant effects were seen on pain at all evaluations and on stiffness after 6 and 12 weeks. Between group analysis did not reveal significant improvements over time. Analysis of ADL score for the PEMF-treated group revealed a significant correlation between less improvement and increasing age. Analysis of patients <65 years using between group analysis revealed a significant improvement for stiffness on treated knee after 2 weeks, but this effect was not observed for ADL and pain. CONCLUSIONS: Applying between group analysis we were unable to demonstrate a beneficial symptomatic effect of PEMF in the treatment of knee OA in all patients. However, in patients <65 years of age there is significant and beneficial effect of treatment related to stiffness.",

author = "G Thamsborg and A Florescu and P Oturai and E Fallentin and K Tritsaris and S Dissing",

note = "Keywords: Activities of Daily Living; Double-Blind Method; Electromagnetic Fields; Female; Humans; Male; Middle Aged; Movement Disorders; Osteoarthritis, Knee; Pain; Physical Examination; Questionnaires",

year = "2005",

doi = "10.1016/j.joca.2005.02.012",

language = "English",

volume = "13",

pages = "575--81",

journal = "Osteoarthritis and Cartilage",

issn = "1063-4584",

publisher = "Elsevier",

number = "7",

}

TY - JOUR

T1 - Treatment of knee osteoarthritis with pulsed electromagnetic fields: a randomized, double-blind, placebo-controlled study

AU - Thamsborg, G

AU - Florescu, A

AU - Oturai, P

AU - Fallentin, E

AU - Tritsaris, K

AU - Dissing, S

N1 - Keywords: Activities of Daily Living; Double-Blind Method; Electromagnetic Fields; Female; Humans; Male; Middle Aged; Movement Disorders; Osteoarthritis, Knee; Pain; Physical Examination; Questionnaires

PY - 2005

Y1 - 2005

N2 - OBJECTIVE: The investigation aimed at determining the effectiveness of pulsed electromagnetic fields (PEMF) in the treatment of osteoarthritis (OA) of the knee by conducting a randomized, double-blind, placebo-controlled clinical trial. DESIGN: The trial consisted of 2h daily treatment 5 days per week for 6 weeks in 83 patients with knee OA. Patient evaluations were done at baseline and after 2 and 6 weeks of treatment. A follow-up evaluation was done 6 weeks after treatment. Activities of daily living (ADL), pain and stiffness were evaluated using the Western Ontario and McMaster Universities (WOMAC) questionnaire. RESULTS: Within group analysis revealed a significant improvement in ADL, stiffness and pain in the PEMF-treated group at all evaluations. In the control group there was no effect on ADL after 2 weeks and a weak significance was seen after 6 and 12 weeks. Significant effects were seen on pain at all evaluations and on stiffness after 6 and 12 weeks. Between group analysis did not reveal significant improvements over time. Analysis of ADL score for the PEMF-treated group revealed a significant correlation between less improvement and increasing age. Analysis of patients <65 years using between group analysis revealed a significant improvement for stiffness on treated knee after 2 weeks, but this effect was not observed for ADL and pain. CONCLUSIONS: Applying between group analysis we were unable to demonstrate a beneficial symptomatic effect of PEMF in the treatment of knee OA in all patients. However, in patients <65 years of age there is significant and beneficial effect of treatment related to stiffness.

AB - OBJECTIVE: The investigation aimed at determining the effectiveness of pulsed electromagnetic fields (PEMF) in the treatment of osteoarthritis (OA) of the knee by conducting a randomized, double-blind, placebo-controlled clinical trial. DESIGN: The trial consisted of 2h daily treatment 5 days per week for 6 weeks in 83 patients with knee OA. Patient evaluations were done at baseline and after 2 and 6 weeks of treatment. A follow-up evaluation was done 6 weeks after treatment. Activities of daily living (ADL), pain and stiffness were evaluated using the Western Ontario and McMaster Universities (WOMAC) questionnaire. RESULTS: Within group analysis revealed a significant improvement in ADL, stiffness and pain in the PEMF-treated group at all evaluations. In the control group there was no effect on ADL after 2 weeks and a weak significance was seen after 6 and 12 weeks. Significant effects were seen on pain at all evaluations and on stiffness after 6 and 12 weeks. Between group analysis did not reveal significant improvements over time. Analysis of ADL score for the PEMF-treated group revealed a significant correlation between less improvement and increasing age. Analysis of patients <65 years using between group analysis revealed a significant improvement for stiffness on treated knee after 2 weeks, but this effect was not observed for ADL and pain. CONCLUSIONS: Applying between group analysis we were unable to demonstrate a beneficial symptomatic effect of PEMF in the treatment of knee OA in all patients. However, in patients <65 years of age there is significant and beneficial effect of treatment related to stiffness.

U2 - 10.1016/j.joca.2005.02.012

DO - 10.1016/j.joca.2005.02.012

M3 - Journal article

C2 - 15979009

SN - 1063-4584

VL - 13

SP - 575

EP - 581

JO - Osteoarthritis and Cartilage

JF - Osteoarthritis and Cartilage

IS - 7

ER -