Trichuris suis ova therapy for allergic rhinitis: a randomized, double-blind, placebo-controlled clinical trial

Peter Bager; John Arnved; Steen Rønborg; Jan Wohlfahrt; Lars K Poulsen; Tine Westergaard; Henning Willads Petersen; Bjarne Kristensen; Stig Thamsborg; Allan Roepstorff; Christian Kapel; Mads Melbye

doi:10.1016/j.jaci.2009.08.006

Trichuris suis ova therapy for allergic rhinitis: a randomized, double-blind, placebo-controlled clinical trial

Peter Bager, John Arnved, Steen Rønborg, Jan Wohlfahrt, Lars K Poulsen, Tine Westergaard, Henning Willads Petersen, Bjarne Kristensen, Stig Thamsborg, Allan Roepstorff, Christian Kapel, Mads Melbye

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

166 Citationer (Scopus)

Abstract

Parasitic helminth infections can protect against allergic airway inflammation in experimental models and have been associated with a reduced risk of atopy and a reduced course of asthma in some observational studies. Although no clinical evidence exists to support the use of helminth therapy for allergic disease, the helminth Trichuris suis has demonstrated efficacy in treatment of inflammatory bowel disease.

Originalsprog	Engelsk
Tidsskrift	Journal of Allergy and Clinical Immunology
Vol/bind	125
Udgave nummer	1
Sider (fra-til)	123-30.e1-3
ISSN	0091-6749
DOI	https://doi.org/10.1016/j.jaci.2009.08.006
Status	Udgivet - 1 jan. 2010

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10.1016/j.jaci.2009.08.006

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Citationsformater

Bager, P., Arnved, J., Rønborg, S., Wohlfahrt, J., Poulsen, L. K., Westergaard, T., Petersen, H. W., Kristensen, B., Thamsborg, S., Roepstorff, A., Kapel, C., & Melbye, M. (2010). Trichuris suis ova therapy for allergic rhinitis: a randomized, double-blind, placebo-controlled clinical trial. Journal of Allergy and Clinical Immunology, 125(1), 123-30.e1-3. https://doi.org/10.1016/j.jaci.2009.08.006

Bager, P, Arnved, J, Rønborg, S, Wohlfahrt, J, Poulsen, LK, Westergaard, T, Petersen, HW, Kristensen, B, Thamsborg, S, Roepstorff, A, Kapel, C & Melbye, M 2010, 'Trichuris suis ova therapy for allergic rhinitis: a randomized, double-blind, placebo-controlled clinical trial', Journal of Allergy and Clinical Immunology, bind 125, nr. 1, s. 123-30.e1-3. https://doi.org/10.1016/j.jaci.2009.08.006

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abstract = "Parasitic helminth infections can protect against allergic airway inflammation in experimental models and have been associated with a reduced risk of atopy and a reduced course of asthma in some observational studies. Although no clinical evidence exists to support the use of helminth therapy for allergic disease, the helminth Trichuris suis has demonstrated efficacy in treatment of inflammatory bowel disease.",

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AU - Bager, Peter

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AU - Wohlfahrt, Jan

AU - Poulsen, Lars K

AU - Westergaard, Tine

AU - Petersen, Henning Willads

AU - Kristensen, Bjarne

AU - Thamsborg, Stig

AU - Roepstorff, Allan

AU - Kapel, Christian

AU - Melbye, Mads

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AB - Parasitic helminth infections can protect against allergic airway inflammation in experimental models and have been associated with a reduced risk of atopy and a reduced course of asthma in some observational studies. Although no clinical evidence exists to support the use of helminth therapy for allergic disease, the helminth Trichuris suis has demonstrated efficacy in treatment of inflammatory bowel disease.

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DO - 10.1016/j.jaci.2009.08.006

M3 - Journal article

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