Zinc induced folding is essential for TIM15 activity as an mtHsp70 chaperone

Hugo Fraga; Elena Papaleo; Sonia Vega; Adrián Velazquez-Campoy; Salvador Ventura

doi:10.1016/j.bbagen.2012.10.002

Zinc induced folding is essential for TIM15 activity as an mtHsp70 chaperone

Hugo Fraga, Elena Papaleo, Sonia Vega, Adrián Velazquez-Campoy, Salvador Ventura

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning

10 Citationer (Scopus)

Abstract

TIM15/Zim17 in yeast and its mammalian ortholog Hep are Zn(2+) finger (Cys4) proteins that assist mtHsp70 in protein import into the mitochondrial matrix.

Originalsprog	Engelsk
Tidsskrift	BBA General Subjects
Vol/bind	1830
Udgave nummer	1
Sider (fra-til)	2139-2149
Antal sider	11
ISSN	0304-4165
DOI	https://doi.org/10.1016/j.bbagen.2012.10.002
Status	Udgivet - 2013
Udgivet eksternt	Ja

Adgang til dokumentet

10.1016/j.bbagen.2012.10.002

Citationsformater

@article{be22eb47ec4840959254c586139a4507,

title = "Zinc induced folding is essential for TIM15 activity as an mtHsp70 chaperone",

abstract = "TIM15/Zim17 in yeast and its mammalian ortholog Hep are Zn(2+) finger (Cys4) proteins that assist mtHsp70 in protein import into the mitochondrial matrix.",

keywords = "HSP70 Heat-Shock Proteins, Mitochondria, Mitochondrial Proteins, Molecular Dynamics Simulation, Protein Folding, Protein Transport, Saccharomyces cerevisiae, Saccharomyces cerevisiae Proteins, Zinc",

author = "Hugo Fraga and Elena Papaleo and Sonia Vega and Adri{\'a}n Velazquez-Campoy and Salvador Ventura",

year = "2013",

doi = "10.1016/j.bbagen.2012.10.002",

language = "English",

volume = "1830",

pages = "2139--2149",

journal = "BBA General Subjects",

issn = "0304-4165",

publisher = "Elsevier",

number = "1",

}

TY - JOUR

T1 - Zinc induced folding is essential for TIM15 activity as an mtHsp70 chaperone

AU - Fraga, Hugo

AU - Papaleo, Elena

AU - Vega, Sonia

AU - Velazquez-Campoy, Adrián

AU - Ventura, Salvador

PY - 2013

Y1 - 2013

N2 - TIM15/Zim17 in yeast and its mammalian ortholog Hep are Zn(2+) finger (Cys4) proteins that assist mtHsp70 in protein import into the mitochondrial matrix.

AB - TIM15/Zim17 in yeast and its mammalian ortholog Hep are Zn(2+) finger (Cys4) proteins that assist mtHsp70 in protein import into the mitochondrial matrix.

KW - HSP70 Heat-Shock Proteins

KW - Mitochondria

KW - Mitochondrial Proteins

KW - Molecular Dynamics Simulation

KW - Protein Folding

KW - Protein Transport

KW - Saccharomyces cerevisiae

KW - Saccharomyces cerevisiae Proteins

KW - Zinc

U2 - 10.1016/j.bbagen.2012.10.002

DO - 10.1016/j.bbagen.2012.10.002

M3 - Journal article

C2 - 23063975

SN - 0304-4165

VL - 1830

SP - 2139

EP - 2149

JO - BBA General Subjects

JF - BBA General Subjects

IS - 1

ER -