CNS Drug Delivery and Barrier Modelling

Research output

Research output per year 1995 2018 2020 2021 2022 2023 2024 2025

• 50 Journal article
• 4 Book chapter
• 3 Conference abstract in journal
• 3 Review
• 6 More
  • 2 Preprint
  • 1 Book
  • 1 Poster
  • 1 Comment/debate
  • 1 Contribution to newspaper - Newspaper article

Research output per year

Research output per year

Search results

• 2025

  The PSD-95 inhibitor NA-1 is delivered to the brain upon nasal administration with uptake into the olfactory bulb improved by co-administration with the cell-penetrating peptides lowPro and Tat

  Schmidt, S. E., Sandbjerg, C., Joensen, G., Thaysen, M., Gammelgaard, B., Schindowski, K. & Kristensen, M., 2025, (Accepted/In press) In: Drug Delivery and Translational Research.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access
• 2024

  Almen Farmaci

  Mulvad, H. (Editor), Larsen, B. B. (Editor), Jørgensen, L. (Editor) & Jacobsen, J. (Editor), 2024, 5 ed. Samfundslitteratur. 388 p.

  Research output: Book/Report › Book › Education

• Application of a new MDCKII-MDR1 cell model to measure the extent of drug distribution in vitro at equilibrium for prediction of in vivo unbound brain-to-plasma drug distribution

  Langthaler, K., Jones, C. R., Saaby, L., Bundgaard, C. & Brodin, B., 2024, In: Fluids and Barriers of the CNS. 21, 1, 15 p., 11.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  2 Citations (Scopus)

  29 Downloads (Pure)

• Establishment and evaluation of radioresistant models from patient derived tissue

  Cold, S., Alfsen, M. Z., Thaysen, M., Ariey-Bonnet, J., Boge, R. N., Papin, E., Nielsen, N., Michler, I., Kristensen, L. K., Wick, M., Kjaer, A., Wennerberg, K., Nielsen, C. H. & Gnosa, S., 2024, In: European Journal of Cancer. 211, Suppl. 1, p. S104-S104 PB260.

  Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

• Generation of an iPSC-line (BIONi010C-48) with restored P-glycoprotein functionality following transfection with the human MDR1 gene in the AAVS1 locus

  Nielsen, A. K. R., Lilieholm-Røngren, L., Schmid, B., Holst, B., Brodin, B. & Saaby, L., 2024, In: Stem Cell Research. 76, 5 p., 103348.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  25 Downloads (Pure)

• Insulin-inspired peptides may open new pathways to treat Alzheimer's disease

  Kristensen, M., 3 Dec 2024, In: Proceedings of the National Academy of Sciences of the United States of America. 121, 49, 3 p., e2419741121.

  Research output: Contribution to journal › Comment/debate › Research › peer-review

  Open Access

  File
  1 Downloads (Pure)

• Neonatal intestinal mucus barrier changes in response to maturity, inflammation, and sodium decanoate supplementation

  Mortensen, J. S., Bohr, S. S. R., Krog, L. S., Bøtker, J. P., Kapousidou, V., Saaby, L., Hatzakis, N. S., Mørck Nielsen, H., Nguyen, D. N. & Rønholt, S., 2024, In: Scientific Reports. 14, 1, 17 p., 7665.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  1 Citation (Scopus)

  37 Downloads (Pure)

• Regional distribution of unbound eletriptan and sumatriptan in the CNS and PNS in rats: implications for a potential central action

  Svane, N. I., Bällgren, F., Ginosyan, A., Kristensen, M., Larsen, B. B. & Loryan, I., 2024, In: Journal of Headache and Pain. 25, 17 p., 187.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  1 Citation (Scopus)

• Rodent ischemic stroke models and their relevance in preclinical research

  Thaysen, M., Westi, E. W., N. Clarkson, A., Wellendorph, P. & Kristensen, M., 2024, In: Neuroprotection. 2, 4, p. 296-309

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  10 Downloads (Pure)

• The putative proton-coupled organic cation antiporter is involved in uptake of triptans into human brain capillary endothelial cells

  Svane, N. I., Pedersen, A. B. V., Rodenberg, A., Ozgür, B., Saaby, L., Bundgaard, C., Kristensen, M., Tfelt-Hansen, P. & Larsen, B. B., 2024, In: Fluids and Barriers of the CNS. 21, 19 p., 39.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  3 Citations (Scopus)

  15 Downloads (Pure)

• The solute carrier SLC7A1 may act as a protein transporter at the blood-brain barrier

  Kurtyka, M., Wessely, F., Bau, S., Ifie, E., He, L., de Wit, N. M., Pedersen, A. B. V., Keller, M., Webber, C., de Vries, H. E., Ansorge, O., Betsholtz, C., De Bock, M., Chaves, C., Brodin, B., Nielsen, M. S., Neuhaus, W., Bell, R. D., Letoha, T. & Meyer, A. H. & 7 others, Leparc, G., Lenter, M., Lesuisse, D., Cader, Z. M., Buckley, S. T., Loryan, I. & Pietrzik, C. U., 2024, In: European Journal of Cell Biology. 103, 2, 14 p., 151406.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  3 Citations (Scopus)

  15 Downloads (Pure)
• 2023

  Apicobasal transferrin receptor localization and trafficking in brain capillary endothelial cells

  Nielsen, S. S. E., Holst, M. R., Langthaler, K., Bruun, E. H., Brodin, B. & Nielsen, M. S., 2023, In: Fluids and Barriers of the CNS. 20, 1, 15 p., 2.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  9 Citations (Scopus)

  57 Downloads (Pure)

• Assessing extent of brain penetration in vivo (K_p,uu,brain) in Göttingen minipig using a diverse set of reference drugs

  Langthaler, K., Jones, C. R., Brodin, B. & Bundgaard, C., 2023, In: European Journal of Pharmaceutical Sciences. 190, 11 p., 106554.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  6 Citations (Scopus)

  20 Downloads (Pure)

• Cell-Penetrating Peptides as Tools to Facilitate Oral Delivery of Biopharmaceuticals

  Asgreen, C. J., Fredholt, F., Nielsen, H. M. & Kristensen, M., 2023, Cell-Penetrating Peptides: Design, Development and Applications. Oba, M. & Demizu , Y. (eds.). Wiley-VCH, p. 331-354

  Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

• Characterization of an iPSC-based barrier model for blood-brain barrier investigations using the SBAD0201 stem cell line

  Ozgür, B., Puris, E., Brachner, A., Appelt-Menzel, A., Oerter, S., Balzer, V., Holst, M. R., Christiansen, R. F., Hyldig, K., Buckley, S. T., Kristensen, M., Auriola, S., Jensen, A., Fricker, G., Nielsen, M. S., Neuhaus, W. & Brodin, B., 2023, In: Fluids and Barriers of the CNS. 20, 1, 15 p., 96.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  4 Citations (Scopus)

  35 Downloads (Pure)

• Epithelium dynamics differ in time and space when exposed to the permeation enhancers penetramax and EGTA. A head-to-head mechanistic comparison

  Panou, D. A., Pedersen, S. H. F., Kristensen, M. & Nielsen, H. M., 2023, In: Frontiers in Drug Delivery. 3, 16 p., 1221628.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  32 Downloads (Pure)

• Iron Oxide Nanoparticles as a Contrast Agent for Synchrotron Imaging of Sperm

  Lindhøj, M. B., Cooper, S. R., Anker, A. S., Bonnin, A., Kristensen, M., Qvortrup, K., Almstrup, K., Jensen, K. M. Ø., Dyrby, T. B. & Sporring, J., 2023, arxiv.org, 21 p.

  Research output: Working paper › Preprint

  Open Access

  File
  19 Downloads (Pure)

• Selenomethionine as alternative label to the fluorophore TAMRA when exploiting cell-penetrating peptides as blood-brain barrier shuttles to better mimic the physicochemical properties of the non-labelled peptides

  Ýr Þorgeirsdóttir, D., Hofman Andersen, J., Perch-Nielsen, M., Møller, L. H., Grønbæk-Thorsen, F., Kolberg, H. G., Gammelgaard, B. & Kristensen, M., 2023, In: European Journal of Pharmaceutical Sciences. 183, 10 p., 106400.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  7 Citations (Scopus)

  42 Downloads (Pure)

• Subcellular trafficking and transcytosis efficacy of different receptor types for therapeutic antibody delivery at the blood‒brain barrier

  Holst, M. R., de Wit, N. M., Ozgür, B., Brachner, A., Hyldig, K., Appelt-Menzel, A., Sleven, H., Cader, Z., de Vries, H. E., Neuhaus, W., Jensen, A., Brodin, B. & Nielsen, M. S., 2023, In: Fluids and Barriers of the CNS. 20, 1, 17 p., 82.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  3 Citations (Scopus)

  20 Downloads (Pure)
• 2022

  Barrier properties of ex vivo porcine intestinal mucus are highly independent of isolation and storage conditions

  Støvring Mortensen, J., Saaby, L., Harloff-Helleberg, S. & Mørck Nielsen, H., 2022, In: European Journal of Pharmaceutics and Biopharmaceutics. 174, p. 106-110

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  7 Citations (Scopus)

  83 Downloads (Pure)

• Cell-Penetrating Peptides as Carriers for Transepithelial Drug Delivery

  Panou, D. A., Diedrichsen, R. G., Kristensen, M. & Nielsen, H. M., 2022, Cell Penetrating Peptides: Methods and Protocols. Langel, Ü. (ed.). Springer, p. 371-384 (Methods in Molecular Biology, Vol. 2383).

  Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
  4 Citations (Scopus)

• Characterisation of intravenous pharmacokinetics in Göttingen minipig and clearance prediction using established in vitro to in vivo extrapolation methodologies

  Langthaler, K., Jones, C. R., Christensen, R. B., Eneberg, E., Brodin, B. & Bundgaard, C., 2022, In: Xenobiotica. 52, 6, p. 591-607

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  5 Citations (Scopus)

  26 Downloads (Pure)

• En af hjernens forsvarsmure: Blod-hjerne-barrieren

  Ozgür, B., 2022, In: Pharma. 2022, 4, p. 15-17

  Research output: Contribution to journal › Contribution to newspaper - Newspaper article

  Open Access

  File
  31 Downloads (Pure)

• Generation of transient and tunable oxygen gradients in microfluidic channels utilizing the oxygen scavenging properties of thiol-ene polymers

  Yuan, Z., Sticker, D., Helms, H. C. C. & Kutter, J. P., 2022, In: Microfluidics and Nanofluidics. 26, 6, 10 p., 42.

  Research output: Contribution to journal › Journal article › Research › peer-review
  1 Citation (Scopus)

• Highly cationic cell-penetrating peptides affect the barrier integrity and facilitates mannitol permeation in a human stem cell-based blood-brain barrier model

  Frøslev, P., Franzyk, H., Ozgür, B., Larsen, B. B. & Kristensen, M., 2022, In: European Journal of Pharmaceutical Sciences. 168, 10 p., 106054.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  13 Citations (Scopus)

  120 Downloads (Pure)

• Hypoxia increases expression of selected blood–brain barrier transporters GLUT-1, P-gp, SLC7A5 and TFRC, while maintaining barrier integrity, in brain capillary endothelial monolayers

  Ozgür, B., Helms, H. C. C., Tornabene, E. & Larsen, B. B., 2022, In: Fluids and Barriers of the CNS. 19, 1, 17 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  29 Citations (Scopus)

  25 Downloads (Pure)

• Physical and barrier changes in gastrointestinal mucus induced by the permeation enhancer sodium 8-[(2-hydroxybenzoyl)amino]octanoate (SNAC)

  Mortensen, J. S., Bohr, S. S. R., Harloff-Helleberg, S., Hatzakis, N. S., Saaby, L. & Nielsen, H. M., 2022, In: Journal of Controlled Release. 352, p. 163-178 16 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  12 Citations (Scopus)

  86 Downloads (Pure)

• Sortilin regulates blood-brain barrier integrity

  Toth, A. E., Helms, H. C., Harazin, A., Johnsen, K. B., Goldeman, C., Burkhart, A., Thomsen, M. S., Kempen, P. J., Klepe, A., Lipka, D. V., Møller, P. L., Andresen, T. L., Nyegaard, M., Moos, T., Brodin, B. & Nielsen, M. S., 2022, In: The FEBS Journal. 289, 4, p. 1062-1079

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  9 Citations (Scopus)

  19 Downloads (Pure)

• Tanycytes control hypothalamic liraglutide uptake and its anti-obesity actions

  Imbernon, M., Saponaro, C., Helms, H. C. C., Duquenne, M., Fernandois, D., Deligia, E., Denis, R. G. P., Chao, D. H. M., Rasika, S., Staels, B., Pattou, F., Pfrieger, F. W., Brodin, B., Luquet, S., Bonner, C. & Prevot, V., 2022, In: Cell Metabolism. 34, 7, p. 1054-1063.e7

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  58 Citations (Scopus)

  14 Downloads (Pure)

• The Cell-Penetrating Peptide Tat Facilitates Effective Internalization of PSD-95 Inhibitors Into Blood–Brain Barrier Endothelial Cells but less Efficient Permeation Across the Blood–Brain Barrier In Vitro and In Vivo

  Lisa Al Humaidan, E., Lund Pedersen, S., Burkhart, A., Laurfelt Munch Rasmussen, C., Moos, T., Fuchs, P., Alves Fernandes, E. F., Ozgür, B., Strømgaard, K., Bach, A., Larsen, B. B. & Kristensen, M., 2022, In: Frontiers in Drug Delivery - CNS Drug Delivery. 2, 17 p., 854703.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  87 Downloads (Pure)
• 2021

  ATP induces contraction of cultured brain capillary pericytes, via activation of P2Y type purinergic receptors

  Hørlyck, S., Cai, C., Helms, H. C., Lauritzen, M. & Brodin, B., 2021, In: American Journal of Physiology: Heart and Circulatory Physiology. 320, p. H699–H712 14 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  18 Citations (Scopus)

• Brain endothelial cells metabolize glutamate via glutamate dehydrogenase to replenish TCA-intermediates and produce ATP under hypoglycemic conditions

  Hinca, S. B., Salcedo, C., Wagner, A., Goldeman, C., Sadat, E., Aibar, M. M. D., Maechler, P., Brodin, B., Aldana, B. I. & Helms, H. C. C., 2021, In: Journal of Neurochemistry. 157, 6, p. 1861-1875

  Research output: Contribution to journal › Journal article › Research › peer-review
  11 Citations (Scopus)

• Gluten Degradation, Pharmacokinetics, Safety, and Tolerability of TAK-062, an Engineered Enzyme to Treat Celiac Disease

  Pultz, I. S., Hill, M., Vitanza, J. M., Wolf, C., Saaby, L., Liu, T., Winkle, P. & Leffler, D. A., Jul 2021, In: Gastroenterology. 161, 1, p. 81-93.e3

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  56 Citations (Scopus)

  11 Downloads (Pure)

• Human induced pluripotent stem cells (BIONi010-C) generate tight cell monolayers with blood-brain barrier traits and functional expression of large neutral amino acid transporter 1 (SLC7A5)

  Goldeman, C., Andersen, M., Al-Robai, A., Buchholtz, T., Svane, N., Ozgür, B., Holst, B., Shusta, E., Hall, V. J., Saaby, L., Hyttel, P. & Brodin, B., 2021, In: European Journal of Pharmaceutical Sciences. 156, 14 p., 105577.

  Research output: Contribution to journal › Journal article › Research › peer-review
  14 Citations (Scopus)

• Precapillary sphincters and pericytes at first-order capillaries as key regulators for brain capillary perfusion

  Zambach, S. A., Cai, C., Helms, H. C. C., Hald, B. O., Dong, Y., Fordsmann, J. C., Nielsen, R. M., Hu, J., Lønstrup, M., Brodin, B. & Lauritzen, M. J., 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 26, e2023749118.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access
  63 Citations (Scopus)

• Revealing the importance of carrier-cargo association in delivery of insulin and lipidated insulin

  Diedrichsen, R. G., Harloff-Helleberg, S., Werner, U., Besenius, M., Leberer, E., Kristensen, M. & Nielsen, H. M., 2021, In: Journal of Controlled Release. 338, p. 8-21

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  24 Citations (Scopus)

  107 Downloads (Pure)

• Screening novel CNS drug candidates for P-glycoprotein interactions using the cell line iP-gp: In vitro efflux ratios from iP-gp and MDCK-MDR1 monolayers compared to brain distribution data from mice

  Ozgür, B., Saaby, L., Janfelt, C., Langthaler, K., Eneberg, E., Jacobsen, A.-M., Badolo, L., Montanari, D. & Larsen, B. B., 2021, In: European Journal of Pharmaceutics and Biopharmaceutics. 169, p. 211-219

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  6 Citations (Scopus)

  48 Downloads (Pure)

• Tanycytes Control the Hypothalamic Uptake and Metabolic Actions of Liraglutide

  Imbernon, M., Saponaro, C., Helms, H. C. C., Zubiaga, L., Bitsi, S., Duquenne, M., Tomas, A., Chen, S., Salem, V., Deligia, E., Gmyr, V., Denis, R., Kerr-Conte, J., Chao, D. H. M., Beiroa, D., Steals, B., Pattou, F., Pfrieger, F., Brodin, B. & Jones, B. & 3 others, Luquet, S., Bonner, C. & Prevot, V., Jul 2021, In: Glia. 69, S1, p. E237-E237

  Research output: Contribution to journal › Conference abstract in journal › Research

• Tight junctions in the blood–brain barrier promote edema formation and infarct size in stroke – Ambivalent effects of sealing proteins

  Winkler, L., Blasig, R., Breitkreuz-Korff, O., Berndt, P., Dithmer, S., Helms, H. C., Puchkov, D., Devraj, K., Kaya, M., Qin, Z., Liebner, S., Wolburg, H., Andjelkovic, A. V., Rex, A., Blasig, I. E. & Haseloff, R. F., 2021, In: Journal of Cerebral Blood Flow and Metabolism. 41, 1, p. 132-145

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access
  69 Citations (Scopus)

• Transendothelial electrical resistance measurement across the blood–brain barrier: A critical review of methods

  Vigh, J. P., Kincses, A., Ozgür, B., Walter, F. R., Santa-Maria, A. R., Valkai, S., Vastag, M., Neuhaus, W., Brodin, B., Dér, A. & Deli, M. A., 2021, In: Micromachines. 12, 6, 18 p., 685.

  Research output: Contribution to journal › Review › peer-review

  Open Access

  File
  81 Citations (Scopus)

  33 Downloads (Pure)
• 2020

  A novel derivative of thioridazine shows low toxicity and efficient activity against gram‐positive pathogens

  Jørgensen, N. S., Saaby, L., Andersson, A. M., Kromann, S., Sheikhsamani, E., Permin, A., Ronco, T., Svenningsen, S. W., Christensen, J. B. & Olsen, R. H., 2020, In: Antibiotics. 9, 6, 11 p., 327.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  5 Citations (Scopus)

  84 Downloads (Pure)

• Conjugation of Therapeutic PSD-95 Inhibitors to the Cell-Penetrating Peptide Tat Affects Blood-Brain Barrier Adherence, Uptake, and Permeation

  Kristensen, M., Kucharz, K., Felipe Alves Fernandes, E., Strømgaard, K., Schallburg Nielsen, M., Cederberg Helms, H. C., Bach, A., Ulrikkaholm Tofte-Hansen, M., Irene Aldana Garcia, B., Lauritzen, M. & Brodin, B., 2020, In: Pharmaceutics. 12, 7, 24 p., 661.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  27 Citations (Scopus)

  45 Downloads (Pure)

• Culture-induced changes in mRNA expression levels of efflux and SLC-transporters in brain endothelial cells

  Goldeman, C., Ozgür, B. & Brodin, B., 22 Apr 2020, In: Fluids and Barriers of the CNS. 17, 32, 12 p., 32.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  11 Citations (Scopus)

  101 Downloads (Pure)

• Culture of brain capillary pericytes for cytosolic calcium measurements and calcium imaging studies

  Hørlyck, S., Helms, H. C. C. & Brodin, B., May 2020, In: Journal of Visualized Experiments. 159, p. 1-9 9 p., e61253.

  Research output: Contribution to journal › Journal article › Research › peer-review
  2 Citations (Scopus)

• Drug Delivery Strategies to Overcome the Blood-Brain Barrier (BBB)

  Helms, H. C. C., Kristensen, M., Saaby, L., Fricker, G. & Brodin, B., 2020, Handbook of Experimental Pharmacology. Springer, Vol. 273. p. 151-183

  Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication
  18 Citations (Scopus)

• Increased Carrier Peptide Stability through pH Adjustment Improves Insulin and PTH(1-34) Delivery In Vitro and In Vivo Rather than by Enforced Carrier Peptide-Cargo Complexation

  Kristensen, M., Diedrichsen, R. G., Vetri, V., Foderà, V. & Nielsen, H. M., 2020, In: Pharmaceutics. 12, 10, 18 p., 993.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  15 Citations (Scopus)

  80 Downloads (Pure)

• IPEC-J2 rMdr1a, a New Cell Line with Functional Expression of Rat P-glycoprotein Encoded by Rat Mdr1a for Drug Screening Purposes

  Saaby, L., Trasborg, J., Rasmussen, M. A., Holst, B. & Brodin, B., 17 Jul 2020, In: Pharmaceutics. 12, 7, 17 p., 673.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  1 Citation (Scopus)

  74 Downloads (Pure)

• Nitric oxide, KATP channels and endothelin-1 modulate brain pericyte function, vascular tone and neurovascular coupling

  Zambach, S. A., Cai, C., Helms, H. C. C., Hald, B. O., Fordsmann, J. C., Nielsen, R. M., Lønstrup, M., Brodin, B. & Lauritzen, M. J., 8 Jun 2020, bioRxiv, 43 p.

  Research output: Working paper › Preprint

  File
  29 Downloads (Pure)

• The Pyrazolo[3,4-d]pyrimidine Derivative, SCO-201, Reverses Multidrug Resistance Mediated by ABCG2/BCRP

  Ambjørner, S. E. B., Wiese, M., Köhler, S. C., Svindt, J., Lund, X. L., Gajhede, M., Saaby, L., Brodin, B., Rump, S., Weigt, H., Brünner, N. & Stenvang, J., 4 Mar 2020, In: Cells. 9, 3, 22 p., 613.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  14 Citations (Scopus)

  198 Downloads (Pure)
• 2019

  Effects of oxygen-glucose deprivation (OGD) on barrier properties and mRNA transcript levels of selected marker proteins in brain endothelial cells/astrocyte co-cultures

  Tornabene, E., Helms, H. C. C., Pedersen, S. F. & Brodin, B., 2019, In: PLoS ONE. 14, 8, 20 p., e0221103.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  44 Citations (Scopus)

  130 Downloads (Pure)