Pathobiological Sciences

Research output

Research output per year 1991 2017 2019 2020 2021 2022 2023 2024 2024

• 377 Journal article
• 58 Conference abstract for conference
• 36 Review
• 29 Poster
• 66 More
  • 15 Book chapter
  • 10 Conference abstract in journal
  • 8 Editorial
  • 7 Comment/debate
  • 4 Article in proceedings
  • 4 Net publication - Internet publication
  • 3 Doctoral thesis
  • 2 Report
  • 2 Ph.D. thesis
  • 2 Report chapter
  • 1 Book
  • 1 Compendium/lecture notes
  • 1 Paper
  • 1 Conference article
  • 1 Contribution to newspaper - Comment/debate
  • 1 Contribution to newspaper - Feature article
  • 1 Letter
  • 1 Other contribution
  • 1 Preprint

Research output per year

Research output per year

Search results

• 2024

  Animal and Cellular Models of Alzheimer’s Disease

  Baglietto-vargas, D., Freude, K. K. & Garcia-Leon, J. A., 2024, In: Biomedicines. 12, 6, 4 p., 1308.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  3 Downloads (Pure)

• An inactivated SARS-CoV-2 vaccine based on a Vero cell culture-adapted high-titer virus confers cross-protection in small animals

  Offersgaard, A., Duarte Hernandez, C. R., Zhou, Y., Duan, Z., Gammeltoft, K. A., Hartmann, K. T., Fahnøe, U., Marichal-Gallardo, P., Alzua, G. P., Underwood, A. P., Sølund, C., Weis, N., Bonde, J. H., Christensen, J. P., Pedersen, G. K., Jensen, H. E., Holmbeck, K., Bukh, J. & Gottwein, J. M., 2024, In: Scientific Reports. 14, 1, 18 p., 17039.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  6 Downloads (Pure)

• APOE4 IS INSTRUMENTAL IN AUGMENTING RHOA KINASE PHOSPHORYLATION AND CONTRIBUTES THEREBY TO CLASSICAL ALZHEIMER’S DISEASE NEURON PHENOTYPES

  Freude, K. & Tao, R., 5 Mar 2024.

  Research output: Contribution to conference › Conference abstract for conference › Research

  File

• Assessment of abdominal lesions in pigs with wounded umbilical outpouchings transported to slaughter

  Jørgensen, B. M., Jensen, T. B., Becker, C. B., Flyger, C. K., Christensen, M. V., Birch, A. & Jensen, H. E., 2024, In: Porcine Health Management. 10, 7 p., 17.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  7 Downloads (Pure)

• Astrocytes: The Stars in Neurodegeneration?

  Dittlau, K. S. & Freude, K., 2024, In: Biomolecules. 14, 3, 21 p., 289.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  8 Citations (Scopus)

  2 Downloads (Pure)

• Atrial fibrillation as a risk factor for exercise-induced pulmonary haemorrhage following a standardised exercise test

  Hansen, S., Otten, N. D., Nissen, S. D., Carstensen, H., Hopster-Iversen, C., Fjeldborg, J., Staun, S. H., Fenner, M., Hesselkilde, E. M. & Buhl, R., 2024, In: Equine Veterinary Journal. 56, 3, p. 552-561

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  10 Downloads (Pure)

• A weighted and cumulative point system for accurate scoring of intestinal pathology in a piglet model of necrotizing enterocolitis

  Offersen, S. M., Henriksen, N. L. & Brunse, A., 2024, In: Experimental and Molecular Pathology. 140, 11 p., 104936.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File

• Bacterial micro-aggregates as inoculum in animal models of implant-associated infections

  Top Hartmann, K., Lund Nielsen, R., Mikkelsen, F. C., Aalbæk, B., Lichtenberg, M., Holm Jakobsen, T., Bjarnsholt, T., Kvich, L., Ingmer, H., Odgaard, A., Elvang Jensen, H. & Kruse Jensen, L., 2024, In: Biofilm. 7, 12 p., 100200.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  23 Downloads (Pure)

• Båndformede halelæsioner hos malkekøer

  Volhøj, T., Nielsen, C. K., Schjermer, D. M., Jensen, N. S., Jørgensen, B. M., Nielsen, S. S. & Jensen, H. E., 2024, In: Kvaeg. 8, 2 p.

  Research output: Contribution to journal › Journal article › Communication

  File

• Båndformede halelæsioner hos malkekøer

  Volhøj, T., Nielsen, C. K., Schjermer, D. M., Jensen, N. S., Jørgensen, B. M., Nielsen, S. S. & Jensen, H. E., 2024, In: Dansk Veterinaertidsskrift. 107, 6, p. 22-26

  Research output: Contribution to journal › Journal article › Research

  File

• Band-like Tail Lesions in Danish Holstein and Holstein-mix Dairy Cows

  Volhøj, T., Nielsen, C. K., Schjermer, D. M., Jensen, N. S., Jørgensen, B. M., Nielsen, S. S. & Jensen, H. E., 20 May 2024.

  Research output: Contribution to conference › Poster › Research › peer-review

  Open Access

  File
  3 Downloads (Pure)

• Bladder catheterization improves bacterial interference with asymptomatic Escherichia coli 83972 in an experimental porcine model of urinary tract infection

  Stærk, K., Andersen, K., Hjelmager, J. S., Jensen, L. K., Jørgensen, B. M., Møller-Jensen, J., Lund, L. & Andersen, T. E., 2024, (E-pub ahead of print) In: The Journal of Infectious Diseases.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

• Bone infection evolution

  Jensen, L. K., Hartmann, K. T., Witzmann, F., Asbach, P. & Stewart, P. S., 2024, In: Injury. 55, 6 p., 111826.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File

• Bovine Digital Dermatitis: Treponema spp. on trimming equipment and chutes – effect of washing and disinfection

  Ahlén, L., Holmøy, I. H., Sogstad, Å. M., Jensen, T. K., Frosth, S., Rosander, A. & Fjeldaas, T., 2024, In: BMC Veterinary Research. 20, 15 p., 261.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  1 Downloads (Pure)

• Calcium Channels, Clustering, and Single-Amino Acid Control of Blood Pressure and Blood Flow

  Jensen, L. J., 2024, In: Journal of the American Heart Association. 13, 20, p. e038202 4 p.

  Research output: Contribution to journal › Editorial › Research › peer-review

  Open Access

  File

• Canine Myofascial Kinetic Lines: A Descriptive Dissection Study Including Related Function and Locomotion and Comparison of the Human and Equine Myofascial Kinetic Lines

  Elbrønd, V. S., 2024, In: Open Journal of Veterinary Medicine. 14, 9, p. 229-256

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  1 Downloads (Pure)

• Catheter-associated bladder mucosal trauma during intermittent voiding: An experimental study in pigs

  Stærk, K., Schrøder, B., Jensen, L. K., Petersen, T., Andersen, T. E. & Nielsen, L. F., 2024, In: BJUI Compass. 5, 2, p. 217-223 7 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  1 Citation (Scopus)

  11 Downloads (Pure)

• Charting the Explicit Path: Translational Dynamics of Hepatic Bioengineering from Experimental Benchmarks to Practical Bedside Applications

  Radhakrishnan, S., Martin, C. A., Dhayanithy, G., Martin, J. C., Chandrasekaran, A., Kalkura, S. N. & Rela, M., 2024, In: MedLiber of Regenerative Medicine. 2, 1, p. 1-18

  Research output: Contribution to journal › Review › Research › peer-review

  Open Access

  File
  7 Downloads (Pure)

• Clinicopathologic evaluation of congenital idiopathic megaesophagus in a Gordon Setter puppy: a case report and development and application of peripherin immunohistochemistry for detection of ganglion cells

  Becker, C. B. & Jensen, H. E., 2024, In: Journal of Veterinary Diagnostic Investigation. 36, 2, p. 254-257 4 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

• Correction to: Proteomic and Cytokine Profiling in Plasma from Patients with Normal-Tension Glaucoma and Ocular Hypertension (Cellular and Molecular Neurobiology, (2024), 44, 1, (59), 10.1007/s10571-024-01492-3)

  Langbøl, M., Saruhanian, A., Saruhanian, S., Tiedemann, D., Baskaran, T., Vohra, R., Rives, A. S., Moreira, J., Prokosch, V., Liu, H., Lackmann, J. W., Müller, S., Nielsen, C. H., Kolko, M. & Rovelt, J., Dec 2024, In: Cellular and Molecular Neurobiology. 44, 1, 63.

  Research output: Contribution to journal › Comment/debate › Research › peer-review

• CRISPR-Cas9 immune-evasive hESCs are rejected following transplantation into immunocompetent mice

  Frederiksen, H. R., Glantz, A., Vøls, K. K., Skov, S., Tveden-Nyborg, P., Freude, K. & Doehn, U., 2024, In: Frontiers in Genome Editing. 6, 17 p., 1403395.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  1 Downloads (Pure)

• Cutaneous squamous cell carcinoma characterized by MALDI mass spectrometry imaging in combination with machine learning

  Brorsen, L. F., McKenzie, J. S., Tullin, M. F., Bendtsen, K. M. S., Pinto, F. E., Jensen, H. E., Haedersdal, M., Takats, Z., Janfelt, C. & Lerche, C. M., 2024, In: Scientific Reports. 14, 1, 11 p., 11091.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  2 Citations (Scopus)

  12 Downloads (Pure)

• Delayed neutrophil recruitment to the tissue-implant-interface is seen within the first hours following insertion of a contaminated abiotic implant in mice

  Hansen, M. H., Stewart, P. S., Borgogna, T., Bjarnsholt, T. & Jensen, L. K., 26 Jun 2024.

  Research output: Contribution to conference › Conference abstract for conference › Communication

• Distinct calcium sources regulate temporal profiles of NMDAR and mGluR mediated protein synthesis

  Ramakrishna, S., Radhakrishna, B., Kaladiyil, A. P., Shah, N. M., Basavaraju, N., Freude, K. K., Kommaddi, R. P. & Muddashetty, R. S., 2024, In: Life Science Alliance. 7, 8, 19 p., e202402594.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  1 Citation (Scopus)

• Distinct Metabolic Profiles of Ocular Hypertensives in Response to Hypoxia

  Langbøl, M., Rovelt, J., Saruhanian, A., Saruhanian, S., Tiedemann, D., Baskaran, T., Bocca, C., Vohra, R., Cvenkel, B., Lenaers, G. & Kolko, M., 2024, In: International Journal of Molecular Sciences. 25, 1, 18 p., 195.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  1 Citation (Scopus)

  14 Downloads (Pure)

• Effect on calf growth of accounting for early in vitro degradation kinetics when composing a calf starter ration

  Sembach, L. E., Nielsen, L. R. H., Jensen, M. M., Dhakal, R. & Hansen, H. H., 2024, In: Livestock Science. 283, 8 p., 105459.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  9 Downloads (Pure)

• Element Concentrations and Histopathology of Liver and Kidney in West Greenland Ringed Seals (Pusa hispida)

  Andersen-Ranberg, E. U., Leifsson, P. S., Riget, F. F., Søndergaard, J., Andersen, S., Alstrup, A. K. O., Dietz, R. & Sonne, C., 2024, In: Animals. 14, 12, 18 p., 1739.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  1 Citation (Scopus)

  5 Downloads (Pure)

• Equine dental sinusitis—A statistical analysis of the effect of antibiotics on dental sinusitis following dental extraction

  Lydiksen, C. V., Christensen, J. I., Rosenmeier, J. G., Jensen, D. B. & Lindegaard, C., 2024, In: Equine Veterinary Education. 36, 7, p. 357-365

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  2 Downloads (Pure)

• Eradication of Staphylococcus aureus in Implant-Associated Osteomyelitis by an Injectable in situ-Forming Depot Antibiotics Delivery System

  Fuglsang-Madsen, A. J., Henriksen, N. L., Chávez, E. S., Kvich, L. A., Birch, J. K. M., Hartmann, K. T., Eriksen, T., Bjarnsholt, T., Gottlieb, H., Andresen, T. L., Jensen, L. K., Henriksen, J. R. & Hansen, A. E., 2024, In: The Journal of Infectious Diseases. 230, 3, p. 614-623 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  4 Citations (Scopus)

• Experimentally validated modeling of dynamic drug-hERG channel interactions reproducing the binding mechanisms and its importance in action potential duration.

  Escobar, F., Friis, S., Adly, N., Brinkwirth, N., Gomis-Tena, J., Saiz, J., Klaerke, D. A., Stoelzle-Feix, S. & Romero, L., 2024, In: Computer Methods and Programs in Biomedicine. 254, 10 p., 108293.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File

• First hip hemiarthroplasty in a Göttingen Minipig; surgical and post-mortem protocol

  Hartmann, K. T., Odgaard, A., Knudsen, U. K., Aalbæk, B., Kvich, L., Birch, J. M., Petersen, A., Bjarnsholt, T., Jensen, H. E. & Jensen, L. K., 2024, In: Journal of Orthopaedic Surgery and Research. 19, 13 p., 549.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  3 Downloads (Pure)

• Fordele og ulemper ved anvendelse af autologe versus allogene stamceller til behandling af artrose

  Bagge, J., Freude, K., Lindegaard, C., Holst, B. & Hölmich, P., 2024, In: Ugeskrift for Laeger. 186, 7 p., V06230423.

  Research output: Contribution to journal › Journal article › Communication

  Open Access

  File
  17 Downloads (Pure)

• FROM PIXELS TO PIGLETS: UTILIZING DIGITAL IMAGE ANALYSIS AND DEEP LEARNING TO COMBAT PORCINE DIARRHEA

  Becker, C. B., 2024.

  Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  File

• Functional, Structural and Proteomic Effects of Ageing in Resistance Arteries

  Jensen, L. J., 2024, In: International Journal of Molecular Sciences . 25, 5, 22 p., 2601.

  Research output: Contribution to journal › Review › Research › peer-review

  Open Access

  File
  7 Downloads (Pure)

• Generating integration-free pig induced pluripotent stem cells by Episomal Reprogramming

  Enevoldsen, S., Ulrik Lind, J., Freude, K. & Calloe, K., 30 Jun 2024.

  Research output: Contribution to conference › Poster › Communication

  File

• Generation of Human Induced Pluripotent Stem Cell (hiPSC)-Derived Astrocytes for Amyotrophic Lateral Sclerosis and Other Neurodegenerative Disease Studies

  Dittlau, K. S., Chandrasekaran, A., Freude, K. & Van Den Bosch, L., 2024, In: Bio-protocol. 14, 4, 16 p., e4936.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  1 Citation (Scopus)

  11 Downloads (Pure)

• Generation of three isogenic gene-edited Huntington’s disease human embryonic stem cell lines with DOX-inducible NGN2 expression cassette in the AAVS1 safe locus

  Duque Villegas, L. C., Chandrasekaran, A., Flintholm Andersen, S. A., Nørremølle, A., Schmid, B., Pouladi, M. A. & Freude, K., 2024, In: Stem Cell Research. 77, 6 p., 103408.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  9 Downloads (Pure)

• Generation of two patient specific GABRD variants and their isogenic controls for modeling epilepsy

  Kamand, M., Taleb, R., Wathikthinnakon, M., Mohamed, F. A., Ghazanfari, S. P., Konstantinov, D., Hald, J. L., Holst, B., Brasch-Andersen, C., Møller, R. S., Lemke, J. R., Krey, I., Freude, K. & Chandrasekaran, A., 2024, In: Stem Cell Research. 76, 6 p., 103372.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  1 Downloads (Pure)

• Gentamicin and clindamycin antibiotic-eluting depot technology eradicates S. aureus in an implant-associated osteomyelitis pig model without systemic antibiotics

  Henriksen, N. L., Serrano-Chávez, E., Fuglsang-Madsen, A., Jensen, L. K., Gottlieb, H., Bue, M., Andresen, T. L., Henriksen, J. R. & Hansen, A. E., Oct 2024, In: Antimicrobial Agents and Chemotherapy. 68, 10, e00691-24.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access
  1 Citation (Scopus)

• Gentamicin and clindamycin antibiotic-eluting depot technology eradicates S. aureus in an implant-associated osteomyelitis pig model without systemic antibiotics

  Henriksen, N. L., Serrano-Chávez, E., Fuglsang-Madsen, A., Jensen, L. K., Gottlieb, H., Bue, M., Andresen, T. L., Henriksen, J. R. & Hansen, A. E., Oct 2024, In: Antimicrobial Agents and Chemotherapy. 68, 10, e00691-24.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access
  1 Citation (Scopus)

• Grise med små navlebuler kan nå frem til slagtning: I to besætninger med mange grise med navlebuler nåede 41 procent af grisene med navlebule frem til slagtning

  Thorup, F., Christiansen, M. G., Jensen, H. E. & Hovmand-Hansen, T., 2024, In: Magasinet Gris. 2024, 2, p. 36-37

  Research output: Contribution to journal › Journal article › Communication

  File

• Gross pathology and liver mercury concentrations in harbour porpoises, harbour seals and grey seals in Denmark, Northern Europe

  Sonne, C., Alstrup, A. K. O., Pagh, S., Thøstesen, C. B., Jensen, T. H., Jensen, T. K., Galatius, A., Kyhn, L., Søndergaard, J., Siebert, U., Lakemeyer, J. & Dietz, R., 2024, In: Science of the Total Environment. 954, 12 p., 176662.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File

• High fat diet is associated with gut microbiota dysbiosis and decreased gut microbial derived metabolites related to metabolic health in young Göttingen Minipigs

  Lützhøft, D. O., Bækgård, C., Wimborne, E., Straarup, E. M., Pedersen, K. M., Swann, J. R., Pedersen, H. D., Kristensen, K., Morgills, L., Nielsen, D. S., Hansen, A. K., Bracken, M. K., Cirera, S. & Christoffersen, B. Ø., 2024, In: PLoS ONE. 19, 3, 27 p., e0298602.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  2 Citations (Scopus)

  19 Downloads (Pure)

• Human iPSC-derived pericyte-like cells carrying APP Swedish mutation overproduce beta-amyloid and induce cerebral amyloid angiopathy-like changes

  Wu, Y. C., Lehtonen, Š., Trontti, K., Kauppinen, R., Kettunen, P., Leinonen, V., Laakso, M., Kuusisto, J., Hiltunen, M., Hovatta, I., Freude, K., Dhungana, H., Koistinaho, J. & Rolova, T., 2024, In: Fluids and Barriers of the CNS. 21, 20 p., 78.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  1 Downloads (Pure)

• IMPACT OF HANDLING TECHNIQUES ON UMBILICAL ULCERATIONS AND OMPHALITIS IN PIGLETS

  Barington, K., 2024.

  Research output: Contribution to conference › Poster › Research › peer-review

  File

• Implications of SNP-triggered miRNA dysregulation in Schizophrenia development

  Mohamed, F. A. & Freude, K., 2024, In: Frontiers in Genetics. 15, 11 p., 1321232.

  Research output: Contribution to journal › Review › Research › peer-review

  Open Access

  File
  1 Citation (Scopus)

  2 Downloads (Pure)

• Increased glucose metabolism and impaired glutamate transport in human astrocytes are potential early triggers of abnormal extracellular glutamate accumulation in hiPSC-derived models of Alzheimer's disease

  Salcedo, C., Pozo Garcia, V., Garcia-Adan, B., Ameen, A. O., Gegelashvili, G., Waagepetersen, H. S., Freude, K. K. & Aldana, B. I., 2024, In: Journal of Neurochemistry. 168, 5, p. 822-840

  Research output: Contribution to journal › Journal article › Research › peer-review
  7 Citations (Scopus)

• Inflammatory Responses and Sex Differences of Patient Derived Cell Models of Microglia in Alzheimer's Disease

  Haukedal, H., Thomassen, F., Kadlecová, M. & Freude, K., 20 May 2024.

  Research output: Contribution to conference › Poster › Communication

• INTESTINAL AND PERITONEAL LESIONS IN WOUNDED UMBILICAL OUTPOUCHINGS IN PIGS AFTER TRANSPORTATION

  Jensen, H. E., 2024.

  Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  File

• Intranasal Inoculation with Classical Swine Fever Virus Provided a More Consistent Experimental Disease Model Compared to Oral Inoculation

  Hansen, M. S., Nielsen, J., Uttenthal, Å., Jensen, G. Ø. & Lohse, L., 2024, In: Veterinary Sciences. 11, 2, 15 p., 56.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  1 Downloads (Pure)