Anders Aagaard Rehfeld

2022

Human sperm cells can form paracetamol metabolite AM404 that directly interferes with sperm calcium signalling and function through a CatSper-dependent mechanism

Rehfeld, A., Frederiksen, H., Rasmussen, R. H., David, A., Chaker, J., Nielsen, B. S., Nielsen, J. E., Juul, A., Skakkebæk, N. E. & Kristensen, D. M., 2022, In: Human reproduction (Oxford, England). 37, 5, p. 922-935 14 p.

Research output: Contribution to journal › Journal article › Research › peer-review

7 Citations (Scopus)

In vitro investigation of endocrine disrupting effects of pesticides on Ca²⁺-signaling in human sperm cells through actions on the sperm-specific and steroid-activated CatSper Ca²⁺-channel

Birch, M. R., Johansen, M., Skakkebæk, N. E., Andersson, A-M. & Rehfeld, A., 2022, In: Environment International. 167, 15 p., 107399.

Research output: Contribution to journal › Journal article › Research › peer-review

Open Access

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12 Citations (Scopus)

15 Downloads (Pure)

Lupeol and pristimerin do not inhibit activation of the human sperm CatSper Ca(2+)-channel

Rehfeld, A. & Marcus Pedersen, C., 2022, In: F1000Research. 11, 222.

Research output: Contribution to journal › Letter › Research › peer-review

Open Access

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4 Citations (Scopus)

17 Downloads (Pure)

2021

Finasteride interferes with prostaglandin-induced CatSper signalling in human sperm

Birch, M. R., Dissing, S., Skakkebæk, N. E. & Rehfeld, A., 2021, In: Reproduction. 161, 5, p. 561-572 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

8 Citations (Scopus)

The antidepressant Sertraline inhibits CatSper Ca²⁺channels in human sperm

Rahban, R., Rehfeld, A., Schiffer, C., Brenker, C., Egeberg Palme, D. L., Wang, T., Lorenz, J., Almstrup, K., Skakkebaek, N. E., Strünker, T. & Nef, S., 2021, In: Human Reproduction. 36, 10, p. 2638-2648

Research output: Contribution to journal › Journal article › Research › peer-review

Open Access

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18 Citations (Scopus)

21 Downloads (Pure)

The Calcium-Sensing Receptor Is Essential for Calcium and Bicarbonate Sensitivity in Human Spermatozoa

Boisen, I. M., Rehfeld, A., Mos, I., Poulsen, N. N., Nielsen, J. E., Schwarz, P., Rejnmark, L., Dissing, S., Bach-Mortensen, P., Juul, A., Bräuner-Osborne, H., Lanske, B. & Blomberg Jensen, M., 2021, In: The Journal of clinical endocrinology and metabolism. 106, 4, p. e1775-e1792

Research output: Contribution to journal › Journal article › Research › peer-review

14 Citations (Scopus)

UV filters in matched seminal fluid-, urine-, and serum samples from young men

Frederiksen, H., Krause, M., Jørgensen, N., Rehfeld, A., Skakkebæk, N. E. & Andersson, A-M., 2021, In: Journal of Exposure Science and Environmental Epidemiology. 31, p. 345–355

Research output: Contribution to journal › Journal article › Research › peer-review

31 Citations (Scopus)

2020

Bisphenol A Diglycidyl Ether (BADGE) and Bisphenol Analogs, but Not Bisphenol A (BPA), Activate the CatSper Ca2+ Channel in Human Sperm

Rehfeld, A., Andersson, A. M. & Skakkebæk, N. E., 2020, In: Frontiers in Endocrinology. 11, 11 p., 324.

Research output: Contribution to journal › Journal article › Research › peer-review

Open Access

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29 Citations (Scopus)

34 Downloads (Pure)

Bisphenol A Diglycidyl Ether (BADGE) and Progesterone Do Not Induce Ca2+ Signals in Boar Sperm Cells

Rehfeld, A., Mendoza, N., Ausejo, R. & Skakkebæk, N. E., 2020, In: Frontiers in Physiology. 11, p. 785

Research output: Contribution to journal › Journal article › Research › peer-review

Open Access

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1 Citation (Scopus)

15 Downloads (Pure)

Influence of FGF23 and Klotho on male reproduction: Systemic vs direct effects

Bøllehuus Hansen, L., Kaludjerovic, J., Nielsen, J. E., Rehfeld, A., Poulsen, N. N., Ide, N., Skakkebaek, N. E., Frederiksen, H., Juul, A., Lanske, B. & Jensen, M. B., 2020, In: F A S E B Journal. 34, 9, p. 12436-12449

Research output: Contribution to journal › Journal article › Research › peer-review

11 Citations (Scopus)

Revisiting the action of steroids and triterpenoids on the human sperm Ca²⁺ channel CatSper

Rehfeld, A., 2020, In: Molecular Human Reproduction. 26, 11, p. 816–824

Research output: Contribution to journal › Journal article › Research › peer-review

21 Citations (Scopus)

2019

Calcium sensing receptor in male germ cells is essential for processes leading to fertilization

Boisen, I. M., Jensen, M. B., Rehfeld, A., Nielsen, J. E., Juul, A., Mos, I., Brauner-Osborne, H. & Lanske, B., Dec 2019, p. 216-216.

Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

Medium-throughput Screening Assays for Assessment of Effects on Ca2+-Signaling and Acrosome Reaction in Human Sperm

Rehfeld, A., Palme, D. L. E., Almstrup, K., Juul, A. & Skakkebaek, N. E., 2019, In: Journal of Visualized Experiments. 145, p. e59212

Research output: Contribution to journal › Journal article › Research › peer-review

2018

EDC IMPACT: Chemical UV filters can affect human sperm function in a progesterone-like manner

Rehfeld, A., Egeberg, D., Almstrup, K., Holm Petersen, J., Dissing, S. & Skakkebæk, N. E., 2018, In: Endocrine Connections. 7, 1, p. 16-25

Research output: Contribution to journal › Journal article › Research › peer-review

Open Access

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43 Citations (Scopus)

360 Downloads (Pure)

Synergistic activation of CatSper Ca2+ channels in human sperm by oviductal ligands and endocrine disrupting chemicals

Brenker, C., Rehfeld, A., Schiffer, C., Kierzek, M., Kaupp, U. B., Skakkebæk, N. E. & Strünker, T., 2018, In: Human Reproduction. 33, 10, p. 1915-1923 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

37 Citations (Scopus)

Viable acrosome-intact human spermatozoa in the ejaculate as a marker of semen quality and fertility status

Egeberg Palme, D. L., Rehfeld, A., Bang, A. K., Nikolova, K. A., Kjærulff, S., Petersen, M. R., Jeppesen, J. V., Glensbjerg, M., Juul, A., Skakkebæk, N. E., Ziebe, S., Jørgensen, N. & Almstrup, K., 2018, In: Human Reproduction. 33, 3, p. 361-371 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

17 Citations (Scopus)

2017

Compendium of Histology: A Theoretical and Practical Guide

Rehfeld, A., Nylander, M. & Karnov, K., 2017, Springer.

Research output: Book/Report › Book › Research

Do endocrine disrupting chemicals affect human sperm cell function?

Rehfeld, A. A., 27 Sep 2017, Copenhagen University.

Research output: Book/Report › Ph.D. thesis › Research

Selection of High-Quality Spermatozoa May Be Promoted by Activated Vitamin D in the Woman

Bøllehuus Hansen, L., Rehfeld, A., de Neergaard, R., Nielsen, J. E., Iversen, L. H., Boisen, I. M., Mortensen, L. J., Lanske, B., Almstrup, K., Carlsen, E., Berg, A. H., Jørgensen, N., Andersen, A. N., Juul, A. & Blomberg Jensen, M., 2017, In: The Journal of clinical endocrinology and metabolism. 102, 3, p. 950-961 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

23 Citations (Scopus)

2016

Chemical UV Filters Mimic the Effect of Progesterone on Ca(2+) Signaling in Human Sperm Cells

Rehfeld, A., Dissing, S. & Skakkebæk, N. E., Nov 2016, In: Endocrinology. 157, 11, p. 4297-4308 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

41 Citations (Scopus)

In vitro bioassay investigations of the endocrine disrupting potential of steviol glycosides and their metabolite steviol, components of the natural sweetener Stevia

Shannon, M., Rehfeld, A., Frizzell, C., Livingstone, C., McGonagle, C., Skakkebaek, N. E., Wielogórska, E. & Connolly, L., 15 May 2016, In: Molecular and Cellular Endocrinology. 427, p. 65-72

Research output: Contribution to journal › Journal article › Research › peer-review

22 Citations (Scopus)

2014

Alternative polyadenylation of tumor suppressor genes in small intestinal neuroendocrine tumors

Rehfeld, A. A., Plass, M., Døssing, K., Knigge, U., Kjær, A., Krogh, A. & Friis-Hansen, L. J., 2014, In: Frontiers in Endocrinology. 5, 10 p., 46.

Research output: Contribution to journal › Journal article › Research › peer-review

14 Citations (Scopus)

Direct action of endocrine disrupting chemicals on human sperm

Schiffer, C., Müller, A., Egeberg, D. L., Alvarez, L., Brenker, C., Rehfeld, A. A., Frederiksen, H., Wäschle, B., Kaupp, U. B., Balbach, M., Wachten, D., Skakkebaek, N. E., Almstrup, K. & Strünker, T., Jul 2014, In: E M B O Reports. 15, 7, p. 758-65 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Open Access

135 Citations (Scopus)

2013

Alterations in polyadenylation and its implications for endocrine disease

Rehfeld, A. A., Plass, M., Krogh, A. & Friis-Hansen, L., 2013, In: Frontiers in Endocrinology. 4, 23 p., 53.

Research output: Contribution to journal › Review › Research › peer-review

Open Access

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40 Citations (Scopus)

16 Downloads (Pure)

2012

Histologi Kompendium

Rehfeld, A. A., 2012, Munksgaard.

Research output: Book/Report › Book › Education

2010

Birt-Hogg-Dubé syndrom

Translated title of the contribution: Birt-Hogg-Dubé syndromeRehfeld, A. A., van Steensel, M. A. M. & Friis-Hansen, L., 19 Jul 2010, In: Ugeskrift for Laeger. 172, 29, p. 2085-90 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Anders Aagaard Rehfeld

Research output

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