Research output per year
Research output per year
Personal profile
Short presentation
My major research interest is clinical research in critically ill patients. Thus I currently chair the Scandinavian Critical Care Trials Group and the strategic research programme ‘New resuscitation strategies in patients with severe sepsis’. The program is ongoing and will randomize 2000 patients with severe sepsis in 3 RCTs of resuscitation in 25 ICUs in all the Nordic countries. The first RCT, the 6S trial has been published and the second, the TRISS trial, is ongoing and on track.
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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A Core Outcome Set for Adult General ICU Patients
Kjær, M.-B. N., Bruun, C. R. L., Granholm, A., Møller, M. H., Rasmussen, B. S., Mortensen, C. B., Poulsen, L. M., Strøm, T., Laerkner, E., Brøchner, A. C., Haberlandt, T., Bunzel, A.-M. G., Herløv, L. S., Holm, A., Sivapalan, P., Estrup, S., Cronhjort, M., Schandl, A., Laake, J. H. & Hofsø, K. & 25 others, , 2025, In: Critical Care Medicine. 53, 3, p. e575-e589 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
2 Citations (Scopus) -
Adaptations and Heterogeneity of Treatment Effects in Platform Trials-Protocol for Two Methodological Studies
Meyhoff, T. S., Jensen, A. K. G., Perner, A., Goligher, E. C., Campbell, M. K., Møller, M. H. & Granholm, A., 2025, In: Acta Anaesthesiologica Scandinavica. 69, 6, 13 p., e70044.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile9 Downloads (Pure) -
Antibiotics quantification in a compact SERS-based centrifugal microfluidics platform: The case of Meropenem in ICU settings
Badillo-Ramírez, I., Pytlarz, M. A., Soufi, G., Serioli, L., Slipets, R., Perner, A. & Boisen, A., 2025, Photonic Diagnosis, Monitoring, Prevention, and Treatment of Infections and Inflammatory Diseases 2025. Dai, T., Popp, J. & Wu, M. X. (eds.). SPIE, 11 p. 1329803. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE, Vol. 13298).Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review
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Designing and evaluating advanced adaptive randomised clinical trials: a practical guide
Granholm, A., Jensen, A. K. G., Lange, T., Perner, A., Møller, M. H. & Kaas-Hansen, B. S., 2025, In: arXiv. 64 p.Research output: Contribution to journal › Journal article › Research
Open AccessFile5 Downloads (Pure) -
Effects of IV Fluid Restriction According to Standard Fluid Treatment Intensity Across Conservative Versus Liberal Approach to Fluid Therapy of Septic Shock in Intensive Care (CLASSIC) Trial Sites
Sivapalan, P., Kaas-Hansen, B. S., Meyhoff, T. S., Hjortrup, P. B., Kjær, M.-B. N., Laake, J. H., Cronhjort, M., Jakob, S. M., Cecconi, M., Nalos, M., Ostermann, M., Malbrain, M. L. N. G., Møller, M. H., Perner, A. & Granholm, A., 2025, (E-pub ahead of print) In: Critical Care Medicine.Research output: Contribution to journal › Journal article › Research › peer-review
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European Society of Intensive Care Medicine (ESICM) 2025 clinical practice guideline on fluid therapy in adult critically ill patients: part 2-the volume of resuscitation fluids
Mekontso Dessap, A., AlShamsi, F., Belletti, A., De Backer, D., Delaney, A., Møller, M. H., Gendreau, S., Hernandez, G., Machado, F. R., Mer, M., Monge Garcia, M. I., Myatra, S. N., Peng, Z., Perner, A., Pinsky, M. R., Sharif, S., Teboul, J. L., Vieillard-Baron, A., Alhazzani, W. & European Society of Intensive Care Medicine, 2025, In: Intensive Care Medicine. 51, 3, p. 461-477 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
1 Citation (Scopus) -
Evidence-based personalised medicine in critical care: a framework for quantifying and applying individualised treatment effects in patients who are critically ill
Munroe, E. S., Spicer, A., Castellvi-Font, A., Zalucky, A., Dianti, J., Graham Linck, E., Talisa, V., Urner, M., Angus, D. C., Baedorf-Kassis, E., Blette, B., Bos, L. D., Buell, K. G., Casey, J. D., Calfee, C. S., Del Sorbo, L., Estenssoro, E., Ferguson, N. D., Giblon, R. & Granholm, A. & 37 others, , 2025, In: The Lancet Respiratory Medicine. 13, 6, p. 556-568 13 p.Research output: Contribution to journal › Review › peer-review
9 Downloads (Pure) -
Improving Meropenem Quantification in a Compact SERS-Based Centrifugal Microfluidic Platform: Toward TDM of Antibiotics in ICU
Pytlarz, M. A., Soufi, G., Badillo-Ramírez, I., Serioli, L., Slipets, R., Perner, A. & Boisen, A., 2025, In: Analytical Chemistry. 97, 14, p. 7888-7896 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile3 Downloads (Pure)
Activities
- 1 Organisation of and participation in conference
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CORS Annual Conference 2019: Public health and innovation – Is regulation a friend or a foe?
De Bruin, M. L. (Speaker), Hallgreen, C. E. (Speaker), Christiansen, H. (Organizer), Andersen, M. (Speaker), Bjerrum, O. J. (Organizer), Thirstrup, S. (Speaker), Cantarero Arevalo, L. (Speaker), Kimmelman, J. (Invited speaker), Eichler, H.-G. (Invited speaker), Hoogland, H. (Invited speaker), Hoekman, J. (Invited speaker), Gauck, B. (Invited speaker), Perner, A. (Invited speaker) & Wilson, C. (Invited speaker)
18 Nov 2019Activity: Participating in an event - types › Organisation of and participation in conference