Anders Skov Kristensen

Phone+4535336505
Emailasksund.kudk
Websitehttps://ilf.ku.dk

Universitetsparken 2
2100 København Ø

Research activity per year

Keywords

Faculty of Health and Medical Sciences
Neurotransmitter transporters
Glutamat receptorer

2972 Citations
72 Journal article
2 Conference abstract for conference
2 Conference abstract in journal
1 Book chapter
More
- 1 Poster
- 1 Review

Crystal structure of the GluK1 ligand-binding domain with kainate and the full-spanning positive allosteric modulator BPAM538
Bay, Y., Cabello, F. J. M., Koens, C. C., Frantsen, S. M., Pickering, D. S., Frydenvang, K., Francotte, P., Pirotte, B., Kristensen, A. S., Bowie, D. & Kastrup, J. S., 2024, In: Journal of Structural Biology. 216, 3, 9 p., 108113.
Research output: Contribution to journal › Journal article › Research › peer-review

Open Access
File

2 Downloads (Pure)
Fluorescent non-canonical amino acid provides insight into the human serotonin transporter
Nygaard, A., Zachariassen, L. G., Larsen, K. S., Kristensen, A. S. & Loland, C. J., 2024, In: Nature Communications. 15, 1, 9267.
Research output: Contribution to journal › Journal article › Research › peer-review

Open Access
File
Gain-of-function and loss-of-function variants in GRIA3 lead to distinct neurodevelopmental phenotypes
Rinaldi, B., Bayat, A., Zachariassen, L. G., Sun, J-H., Ge, Y-H., Zhao, D., Bonde, K., Madsen, L. H., Awad, I. A. A., Bagiran, D., Sbeih, A., Shah, S. M., El-Sayed, S., Lyngby, S. M., Pedersen, M. G., Stenum-Berg, C., Walker, L. C., Krey, I., Delahaye-Duriez, A., Emrick, L. T. & 67 others, Sully, K., Murali, C. N., Burrage, L. C., Plaud Gonzalez, J. A., Parnes, M., Friedman, J., Isidor, B., Lefranc, J., Redon, S., Heron, D., Mignot, C., Keren, B., Fradin, M., Dubourg, C., Mercier, S., Besnard, T., Cogne, B., Deb, W., Rivier, C., Milani, D., Bedeschi, M. F., Di Napoli, C., Grilli, F., Marchisio, P., Koudijs, S., Veenma, D., Argilli, E., Lynch, S. A., Au, P. Y. B., Ayala Valenzuela, F. E., Brown, C., Masser-Frye, D., Jones, M., Patron Romero, L., Li, W. L., Thorpe, E., Hecher, L., Johannsen, J., Denecke, J., McNiven, V., Szuto, A., Wakeling, E., Cruz, V., Sency, V., Wang, H., Piard, J., Kortüm, F., Herget, T., Bierhals, T., Condell, A., Zeev, B. B., Kaur, S., Christodoulou, J., Piton, A., Zweier, C., Kraus, C., Micalizzi, A., Trivisano, M., Specchio, N., Lesca, G., Møller, R. S., Tümer, Z., Musgaard, M., Gerard, B., Lemke, J. R., Shi, Y. S. & Kristensen, A. S., 2024, In: Brain. 147, 5, p. 1837-1855
Research output: Contribution to journal › Journal article › Research › peer-review

Open Access
File

2 Citations (Scopus)
Small-molecule positive allosteric modulation of homomeric kainate receptors GluK1-3: development of screening assays and insight into GluK3 structure
Bay, Y., Venskutonytė, R., Frantsen, S. M., Thorsen, T. S., Musgaard, M., Frydenvang, K., Francotte, P., Pirotte, B., Biggin, P. C., Kristensen, A. S., Boesen, T., Pickering, D. S., Gajhede, M. & Kastrup, J. S., 2024, In: FEBS Journal. 291, 7, p. 1506-1529
Research output: Contribution to journal › Journal article › Research › peer-review

2 Citations (Scopus)
Structural determinants for activity of the antidepressant vortioxetine at human and rodent 5-HT₃ receptors
López-Sánchez, U., Munro, L. J., Ladefoged, L. K., Pedersen, A. J., Brun, C. C., Lyngby, S. M., Baud, D., Juillan-Binard, C., Pedersen, M. G., Lummis, S. C. R., Bang-Andersen, B., Schiøtt, B., Chipot, C., Schoehn, G., Neyton, J., Dehez, F., Nury, H. & Kristensen, A. S., 2024, In: Nature Structural and Molecular Biology. 31, p. 1232–1242
Research output: Contribution to journal › Journal article › Research › peer-review

File

2 Citations (Scopus)

3 Downloads (Pure)
The positive allosteric modulator BPAM344 and L-glutamate introduce an active-like structure of the ligand-binding domain of GluK2
Bay, Y., Egeberg Jeppesen, M., Frydenvang, K., Francotte, P., Pirotte, B., Pickering, D. S., Kristensen, A. S. & Kastrup, J. S., 2024, In: FEBS Letters. 598, 7, p. 743-757
Research output: Contribution to journal › Journal article › Research › peer-review

Open Access
File

1 Citation (Scopus)

6 Downloads (Pure)
A previously unrecognized superfamily of macro-conotoxins includes an inhibitor of the sensory neuron calcium channel Cav2.3
Hackney, C. M., Flórez Salcedo, P., Mueller, E., Koch, T. L., Kjelgaard, L. D., Watkins, M., Zachariassen, L., Tuelund, P. S., McArthur, J. R., Adams, D. J., Kristensen, A. S., Olivera, B., Finol-Urdaneta, R. K., Safavi-Hemami, H., Morth, J. P. & Ellgaard, L., 2023, In: PLOS Biology. 21, 8, 32 p., e3002217.
Research output: Contribution to journal › Journal article › Research › peer-review

Open Access
File

4 Citations (Scopus)

41 Downloads (Pure)
Structure-Activity Relationship and Solubility Studies of Novel N1-substituted Quinoxaline-2,3-diones as Kainate Receptor Antagonists
Chałupnik, P., Vialko, A., Pickering, D. S., Nielsen, B., Bay, Y., Kristensen, A. S., Hinkkanen, M., Szczepańska, K., Karcz, T., Latacz, G., Johansen, T. N. & Szymanska, E. M., 2023, In: ChemMedChem. 18, 18, 15 p., e202300278.
Research output: Contribution to journal › Journal article › Research › peer-review

Open Access
File

2 Citations (Scopus)

4 Downloads (Pure)

4 Lecture and oral contribution
2 Participation in workshop, seminar, course
1 Organisation of and participation in conference

Use of Voltage-clamp fluorometry for Studies of SERT dynamics: Are you SERTain it’s DAT?
Anders Skov Kristensen (Lecturer)
28 Jan 2015
Activity: Talk or presentation types › Lecture and oral contribution
5th Scandinavian Physiological Society conference on Molecular Approaches to Membrane Transport
Anders Skov Kristensen (Speaker)
18 Sep 2014
Activity: Participating in an event - types › Organisation of and participation in conference
International Conference on Pharmacology and Drug Development
Anders Skov Kristensen (Speaker)
9 Dec 2013
Activity: Participating in an event - types › Participation in workshop, seminar, course
Antidepressant drugs targeting the serotonin and norepinephrine transporters: elucidation of the molecular basis for drug binding and selectivity
Anders Skov Kristensen (Lecturer)
9 Dec 2013
Activity: Talk or presentation types › Lecture and oral contribution
44th Annual Winter Conference on Brain Research
Anders Skov Kristensen (Speaker)
23 Jan 2011
Activity: Talk or presentation types › Lecture and oral contribution
Antidepressant drugs targeting the serotonin and norepinephrine transporters: Elucidation of the molecular basis for drug binding and selectivity
Anders Skov Kristensen (Speaker)
19 Jan 2011
Activity: Talk or presentation types › Lecture and oral contribution
Annual Meeting, Society for Neuroscience
Anders Skov Kristensen (Participant)
14 Nov 2010 → 21 Nov 2010
Activity: Participating in an event - types › Participation in workshop, seminar, course

Anders Skov Kristensen

Personal profile

Keywords

Collaborations and top research areas from the last five years

Dive into details

Crystal structure of the GluK1 ligand-binding domain with kainate and the full-spanning positive allosteric modulator BPAM538

Fluorescent non-canonical amino acid provides insight into the human serotonin transporter

Gain-of-function and loss-of-function variants in GRIA3 lead to distinct neurodevelopmental phenotypes

Small-molecule positive allosteric modulation of homomeric kainate receptors GluK1-3: development of screening assays and insight into GluK3 structure

Structural determinants for activity of the antidepressant vortioxetine at human and rodent 5-HT₃ receptors

The positive allosteric modulator BPAM344 and L-glutamate introduce an active-like structure of the ligand-binding domain of GluK2

A previously unrecognized superfamily of macro-conotoxins includes an inhibitor of the sensory neuron calcium channel Cav2.3

Structure-Activity Relationship and Solubility Studies of Novel N1-substituted Quinoxaline-2,3-diones as Kainate Receptor Antagonists

Use of Voltage-clamp fluorometry for Studies of SERT dynamics: Are you SERTain it’s DAT?

5th Scandinavian Physiological Society conference on Molecular Approaches to Membrane Transport

International Conference on Pharmacology and Drug Development

Antidepressant drugs targeting the serotonin and norepinephrine transporters: elucidation of the molecular basis for drug binding and selectivity

44th Annual Winter Conference on Brain Research

Antidepressant drugs targeting the serotonin and norepinephrine transporters: Elucidation of the molecular basis for drug binding and selectivity

Annual Meeting, Society for Neuroscience

Anders Skov Kristensen

Personal profile

Keywords

Collaborations and top research areas from the last five years

Research output

Activities