Short presentation

In the viral recombination area, I completed studies unravelling the mechanisms of recombination in HIV and their interplay with selective pressure on the viral population. In addition, I contributed significantly to developing systems for the study of HCV recombination, revealing this virus capability for high frequency recombination. I had a major role in developing microscopy and bioinformatics systems to image and track HIV viral particles in real-time, which also allowed my investigations in HCV packaging and subcellular interactions. I also participated in collaborative studies investigating drug resistance development and neutralization of HCV in cell culture systems. More recently, I contributed microscopy data and analyses to studies of the novel SARS-CoV-2 pathogen. I have recently initiated cell culture based studies of HBV biology, including replication, antiviral resistance, and viral clearance.