Research output per year
Research output per year
- 1 - 50 out of 270 results
Search results
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2025
Transdermal delivery of Acheta domesticus protein hydrolysate using nanostructured lipid carriers and Derma Stamp: Does the combination of lipid-based formulation and a physical technique add value for permeation and retention?
Yeerong, K., Czyrski, G. S., Heinz, A., Müllertz, A., Rades, T. & Chaiyana, W., 2025, In: Journal of Drug Delivery Science and Technology. 104, 106470.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile -
2024
Acheta domesticus: A Natural Source of Anti-Skin-Aging Ingredients for Cosmetic Applications
Yeerong, K., Chantawannakul, P., Anuchapreeda, S., Rades, T., Müllertz, A. & Chaiyana, W., 2024, In: Pharmaceuticals. 17, 3, 20 p., 346.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile15 Downloads (Pure) -
Binder jetting 3D printing in fabricating pharmaceutical solid products for precision medicine
Wang, Y., Genina, N., Müllertz, A. & Rantanen, J., 2024, In: Basic & clinical pharmacology & toxicology. 134, 3, p. 325-332Research output: Contribution to journal › Review › Research › peer-review
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Characterizing interregional differences in the rheological properties and composition of rat small intestinal mucus
Klitgaard, M., Jacobsen, J., Kristensen, M. N., Berthelsen, R. & Müllertz, A., 2024, In: Drug Delivery and Translational Research. 14, p. 3309–3320Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile2 Citations (Scopus) -
Chitosan Alginate Nanoparticles of Protein Hydrolysate from Acheta domesticus with Enhanced Stability for Skin Delivery
Yeerong, K., Chantawannakul, P., Anuchapreeda, S., Juntrapirom, S., Kanjanakawinkul, W., Müllertz, A., Rades, T. & Chaiyana, W., 2024, In: Pharmaceutics. 16, 6, 25 p., 724.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile1 Citation (Scopus)14 Downloads (Pure) -
Comparison of the liquisolid technique and co-milling for loading of a poorly soluble drug in inorganic porous excipients
Ogadah, C. U., Mrštná, K., Matysová, L., Müllertz, A., Rades, T., Niederquell, A., Šklubalová, Z. & Vraníková, B., 2024, In: International Journal of Pharmaceutics. 650, 10 p., 123702.Research output: Contribution to journal › Journal article › Research › peer-review
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Development and in vitro evaluation of an infant friendly self-nanoemulsifying drug delivery system (SNEDDS) loaded with an amphotericin B-monoacyl phosphatidylcholine complex for oral delivery
Liu, X., Müllertz, A., Bar-Shalom, D. & Berthelsen, R., 2024, In: International Journal of Pharmaceutics. 660, 8 p., 124286.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile9 Downloads (Pure) -
Influence of preparation method and choice of phospholipid on co-amorphization, physical stability, and dissolution behavior of equimolar indomethacin-phospholipid systems: A case study
Khorami, K., Müllertz, A. & Rades, T., 2024, In: Journal of Drug Delivery Science and Technology. 93, 8 p., 105433.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile19 Downloads (Pure) -
2023
Amphotericin B and monoacyl-phosphatidylcholine form a stable amorphous complex
Liu, X., Berthelsen, R., Bar-Shalom, D., Kjellerup Lind, T., Doutch, J. & Müllertz, A., 2023, In: International Journal of Pharmaceutics. 633, 10 p., 122601.Research output: Contribution to journal › Journal article › Research › peer-review
2 Citations (Scopus) -
Assessing acute colitis induced by dextran sulfate sodium in rats and its impact on gastrointestinal fluids
Klitgaard, M., Kristensen, M. N., Venkatasubramanian, R., Guerra, P., Jacobsen, J., Berthelsen, R., Rades, T. & Müllertz, A., 2023, In: Drug Delivery and Translational Research. 13, p. 1484–1499Research output: Contribution to journal › Journal article › Research › peer-review
2 Citations (Scopus) -
Biorelevant Dissolution of Dipyridamole and Piroxicam Using an Automated UV/Vis Spectrophotometric and Potentiometric Dissolution Testing Platform
Berthelsen, R., Larsen, S. W., Müllertz, A., Box, K. & Østergaard, J., 2023, In: Dissolution Technologies. 30, 3, p. 144-153Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile23 Downloads (Pure) -
Coating of Primary Powder Particles Improves the Quality of Binder Jetting 3D Printed Oral Solid Products
Wang, Y., Genina, N., Müllertz, A. & Rantanen, J., 2023, In: Journal of Pharmaceutical Sciences. 112, 2, p. 506-512Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile8 Citations (Scopus)29 Downloads (Pure) -
Drug Dissolution in Oral Drug Absorption: Workshop Report
Raines, K., Agarwal, P., Augustijns, P., Alayoubi, A., Attia, L., Bauer-Brandl, A., Brandl, M., Chatterjee, P., Chen, H., Yu, Y. C., Coutant, C., Coutinho, A. L., Curran, D., Dressman, J., Ericksen, B., Falade, L., Gao, Y., Gao, Z., Ghosh, D., Ghosh, T. & 26 others, , 2023, In: AAPS Journal. 25, 6, 20 p., 103.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile10 Citations (Scopus)6 Downloads (Pure) -
Functionalized calcium carbonate (FCC) as a novel carrier to solidify supersaturated self-nanoemulsifying drug delivery systems (super-SNEDDS)
Merchant, J., Müllertz, A., Rades, T. & Bannow, J., 2023, In: European Journal of Pharmaceutics and Biopharmaceutics. 193, p. 198-207Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile1 Citation (Scopus)13 Downloads (Pure) -
In vitro-in vivo relationship for amorphous solid dispersions using a double membrane dissolution-permeation setup
Jørgensen, J. R., Mohr, W., Rischer, M., Sauer, A., Mistry, S., Rades, T. & Müllertz, A., 2023, In: European Journal of Pharmaceutics and Biopharmaceutics. 188, p. 26-32Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile5 Citations (Scopus)63 Downloads (Pure) -
Moving perfusion culture and live-cell imaging from lab to disc: proof of concept toxicity assay with AI-based image analysis
Serioli, L., Gruzinskyte, L., Zappalà, G., Hwu, E. T., Laksafoss, T. Z., Jensen, P. L., Demarchi, D., Müllertz, A., Boisen, A. & Zór, K., 2023, In: Lab on a Chip. 23, p. 1603-1612Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile4 Citations (Scopus) -
Stability and intrinsic dissolution of vacuum compression molded amorphous solid dispersions of efavirenz
Jørgensen, J. R., Mohr, W., Rischer, M., Sauer, A., Mistry, S., Müllertz, A. & Rades, T., 2023, In: International Journal of Pharmaceutics. 632, 8 p., 122564.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile7 Citations (Scopus)28 Downloads (Pure) -
The Influence of Blonanserin Supersaturation in Liquid and Silica Stabilised Self-Nanoemulsifying Drug Delivery Systems on In Vitro Solubilisation
Møller, A., Schultz, H. B., Meola, T. R., Joyce, P., Müllertz, A. & Prestidge, C. A., 2023, In: Pharmaceutics. 15, 1, 14 p., 284.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile27 Downloads (Pure) -
2022
Additive Manufacturing of Solid Products for Oral Drug Delivery Using Binder Jetting Three-Dimensional Printing
Wang, Y., Müllertz, A. & Rantanen, J., 2022, In: AAPS PharmSciTech. 23, 6, 196.Research output: Contribution to journal › Review › Research › peer-review
16 Citations (Scopus) -
Combining lipid based drug delivery and amorphous solid dispersions for improved oral drug absorption of a poorly water-soluble drug
Nora, G-I., Venkatasubramanian, R., Strindberg, S., Siqueira-Jørgensen, S. D., Pagano, L., Romanski, F. S., Swarnakar, N. K., Rades, T. & Müllertz, A., 2022, In: Journal of Controlled Release. 349, p. 206-212Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile19 Citations (Scopus)66 Downloads (Pure) -
Development of a Microgram Scale Video-Microscopic Method to Investigate Dissolution Behavior of Poorly Water-Soluble Drugs
Senniksen, M. B., Christfort, J. F., Marabini, R., Spillum, E., Matthews, W., Da Vià, L., Plum, J., Rades, T. & Müllertz, A., 2022, In: AAPS PharmSciTech. 23, 6, 173.Research output: Contribution to journal › Journal article › Research › peer-review
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Direct visualizing of paracetamol immediate release tablet disintegration in vivo and in vitro
Fredholt, F., Di Meo, C., Sloth, S., Müllertz, A. & Berthelsen, R., 2022, In: European Journal of Pharmaceutics and Biopharmaceutics. 180, p. 63-70Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile4 Citations (Scopus)31 Downloads (Pure) -
Elucidating Pathway and Anesthetic Mechanism of Action of Clove Oil Nanoformulations in Fish
Kheawfu, K., Pikulkaew, S., Wellendorph, P., Jørgensen, L. V. G., Rades, T., Mullertz, A. & Okonogi, S., 2022, In: Pharmaceutics. 14, 5, 13 p., 919.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile10 Citations (Scopus)23 Downloads (Pure) -
Formulation, characterization and in-vitro evaluation of self-nanoemulsifying drug delivery system containing rhamnolipid biosurfactant
Khan, M. A., Ullah, K., Rahman, N. U., Mahmood, A., Müllertz, A., Mannan, A., Murtaza, G. & Khan, S. A., 2022, In: Journal of Drug Delivery Science and Technology. 75, 9 p., 103673.Research output: Contribution to journal › Journal article › Research › peer-review
5 Citations (Scopus) -
Impact of oral gavage technique of drug-containing microcontainers on the gastrointestinal transit and absorption in rats
Kristensen, M. N., Rades, T., Boisen, A. & Müllertz, A., 2022, In: International Journal of Pharmaceutics. 618, 121630.Research output: Contribution to journal › Journal article › Research › peer-review
1 Citation (Scopus) -
Investigating the effect of graphene oxide in chitosan/alginate-based foams on the release and antifungal activity of clotrimazole in vitro
Huang, J., Jacobsen, J., Genina, N., Larsen, S. W., Nielsen, H. M., Müllertz, A. & Mu, H., 2022, In: European Journal of Pharmaceutical Sciences. 174, 9 p., 106204.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile5 Citations (Scopus)37 Downloads (Pure) -
Physico-chemical characterization of aspirated and simulated human gastric fluids to study their influence on the intrinsic dissolution rate of cinnarizine
Pedersen, P. B., Berthelsen, R., Rades, T., Jørgensen, S. A., Vilmann, P., Bar-Shalom, D., Baldursdottir, S. & Müllertz, A., 2022, In: International Journal of Pharmaceutics. 622, 7 p., 121856.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile10 Citations (Scopus)40 Downloads (Pure) -
Structured approach for designing drug-loaded solid products by binder jetting 3D printing
Wang, Y., Müllertz, A. & Rantanen, J., 2022, In: European Journal of Pharmaceutical Sciences. 178, 11 p., 106280.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile16 Citations (Scopus)20 Downloads (Pure) -
The Binding of Alpinia galanga Oil and Its Nanoemulsion to Mammal GABA(A) Receptors Using Rat Cortical Membranes and an In Silico Modeling Platform
Khumpirapang, N., Suknuntha, K., Wongrattanakamon, P., Jiranusornkul, S., Anuchapreeda, S., Wellendorph, P., Mullertz, A., Rades, T. & Okonogi, S., 2022, In: Pharmaceutics. 14, 3, 15 p., 650.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile2 Citations (Scopus)20 Downloads (Pure) -
UNGAP best practice for improving solubility data quality of orally administered drugs
Vertzoni, M., Alsenz, J., Augustijns, P., Bauer-Brandl, A., Bergström, C. A. S., Brouwers, J., Müllerz, A., Perlovich, G., Saal, C., Sugano, K. & Reppas, C., 1 Jan 2022, In: European Journal of Pharmaceutical Sciences. 168, 21 p., 106043.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile11 Citations (Scopus)34 Downloads (Pure) -
2021
Bovine Milk-Derived Emulsifiers Increase Triglyceride Absorption in Newborn Formula-Fed Pigs
Knudsen, K. B. K., Heerup, C., Jensen, T. R. S., Geng, X., Drachmann, N., Nordby, P., Jeppesen, P. B., Ifaoui, I., Müllertz, A., Sangild, P. T., Ostenfeld, M. S. & Thymann, T., 2021, In: Nutrients. 13, 2, 15 p., 410.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile12 Citations (Scopus)72 Downloads (Pure) -
Current challenges and future perspectives in oral absorption research: An opinion of the UNGAP network
Vinarov, Z., Abrahamsson, B., Artursson, P., Batchelor, H., Berben, P., Bernkop-Schnurch, A., Butler, J., Ceulemans, J., Davies, N., Dupont, D., Flaten, G. E., Fotaki, N., Griffin, B. T., Jannin, V., Keemink, J., Kesisoglou, F., Koziolek, M., Kuentz, M., Mackie, A., Melendez-Martinez, A. J. & 16 others, , 2021, In: Advanced Drug Delivery Reviews. 171, p. 289-331 43 p.Research output: Contribution to journal › Review › Research › peer-review
Open AccessFile93 Citations (Scopus)79 Downloads (Pure) -
Dairy-derived emulsifiers in infant formula show marginal effects on the plasma lipid profile and brain structure in preterm piglets relative to soy lecithin
Henriksen, N. L., Aasmul-Olsen, K., Venkatasubramanian, R., Nygaard, M. K. E., Sprenger, R. R., Heckmann, A. B., Ostenfeld, M. S., Ejsing, C. S., Eskildsen, S. F., Müllertz, A., Sangild, P. T., Bering, S. B. & Thymann, T., 2021, In: Nutrients. 13, 3, p. 1-18 18 p., 718.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile11 Citations (Scopus)92 Downloads (Pure) -
Design and optimization of self-nanoemulsifying drug delivery systems of clove oil for efficacy enhancement in fish anesthesia
Kheawfu, Pikulkaew, Rades, T., Mullertz, A., Jørgensen, L. V. G. & Okonogi, 2021, In: Journal of Drug Delivery Science and Technology. 61, 9 p., 102241.Research output: Contribution to journal › Journal article › Research › peer-review
13 Citations (Scopus) -
Design of a self-unfolding delivery concept for oral administration of macromolecules
Jørgensen, J. R., Thamdrup, L. H. E., Kamguyan, K., Nielsen, L. H., Nielsen, H. M., Boisen, A., Rades, T. & Müllertz, A., 2021, In: Journal of Controlled Release. 329, p. 948-954Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile27 Citations (Scopus)38 Downloads (Pure) -
Development of gastro-resistant coated probiotic granulates and evaluation of viability and release during simulated upper gastrointestinal transit
Jacobsen, N. M. Y., Nedergaard, H. B., Kock, A., Caglayan, I., Laursen, M. M., Lange, E-M., Marcial-Coba, M. S., Bar-Shalom, D., Nielsen, D. S. & Müllertz, A., 2021, In: LWT. 144, 9 p., 111174.Research output: Contribution to journal › Journal article › Research › peer-review
3 Citations (Scopus) -
Development of Self-Nanoemulsifying Drug Delivery Systems Containing 4-Allylpyrocatechol for Treatment of Oral Infections Caused by Candida albicans
Okonogi, S., Phumat, P., Khongkhunthian, S., Chaijareenont, P., Rades, T. & Mullertz, A., 2021, In: Pharmaceutics. 13, 2, 16 p., 167.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile10 Citations (Scopus)60 Downloads (Pure) -
Drug solubilization during simulated pediatric gastro-intestinal digestion
Kofoed-Djursner, C., Jamil, A., Selen, A., Mullertz, A. & Berthelsen, R., 2021, In: European Journal of Pharmaceutical Sciences. 162, 8 p., 105828.Research output: Contribution to journal › Journal article › Research › peer-review
2 Citations (Scopus) -
Effects of recombinant human gastric lipase and pancreatin during in vitro pediatric gastro-intestinal digestion
Heerup, C., Ebbesen, M. F., Geng, X., Madsen, S. F., Berthelsen, R. & Müllertz, A., 2021, In: Food & Function. 12, 7, p. 2938-2949 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile4 Citations (Scopus)18 Downloads (Pure) -
Estimating the Oral Absorption from Self-Nanoemulsifying Drug Delivery Systems Using an In Vitro Lipolysis-Permeation Method
Klitgaard, M., Mullertz, A. & Berthelsen, R., 2021, In: Pharmaceutics. 13, 4, 14 p., 489.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile12 Citations (Scopus)59 Downloads (Pure) -
Exploring Porcine Gastric and Intestinal Fluids using Microscopic and Solubility Estimates: Impact of Placebo Self-Emulsifying Drug Delivery System Administration to Inform Bio-Predictive in vitro Tools
Bennett-Lenane, H., Jørgensen, J. R., Koehl, N. J., Henze, L. J., O'Shea, J. P., Müllertz, A. & Griffin, B. T., 2021, In: European Journal of Pharmaceutical Sciences. 161, 11 p., 105778.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile3 Citations (Scopus)38 Downloads (Pure) -
Exploring the Impact of Intestinal Fluid Components on the Solubility and Supersaturation of Danazol
Madsen, C. M., Plum, J., Hens, B., Augustijns, P., Mullertz, A. & Rades, T., 2021, In: Journal of Pharmaceutical Sciences. 110, 6, p. 2479-2488 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile2 Citations (Scopus)26 Downloads (Pure) -
Fasted and fed state human duodenal fluids: Characterization, drug solubility, and comparison to simulated fluids and with human bioavailability
Dahlgren, D., Venczel, M., Ridoux, J. P., Skjöld, C., Müllertz, A., Holm, R., Augustijns, P., Hellström, P. M. & Lennernäs, H., 2021, In: European Journal of Pharmaceutics and Biopharmaceutics. 163, p. 240-251Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile41 Citations (Scopus)26 Downloads (Pure) -
Formulation optimization, anesthetic activity, skin permeation, and transportation pathway of Alpinia galanga oil SNEDDS in zebrafish (Danio rerio)
Khumpirapang, N., von Gersdorff Jørgensen, L., Müllertz, A., Rades, T. & Okonogi, S., 2021, In: European Journal of Pharmaceutics and Biopharmaceutics. 165, p. 193-202 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
7 Citations (Scopus) -
Hot punching for loading of biodegradable microcontainers with budesonide-Soluplus film
Abid, Z., Andreoli, F., Kristensen, M. N., Petersen, R. S., Müllertz, A., Boisen, A. & Keller, S. S., 2021, In: Biomedical Microdevices. 23, 11 p., 37.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile1 Citation (Scopus)16 Downloads (Pure) -
INFOGEST inter-laboratory recommendations for assaying gastric and pancreatic lipases activities prior to in vitro digestion studies
Grundy, M. M. L., Abrahamse, E., Almgren, A., Alminger, M., Andres, A., Ariëns, R. M. C., Bastiaan-Net, S., Bourlieu-Lacanal, C., Brodkorb, A., Bronze, M. R., Comi, I., Couëdelo, L., Dupont, D., Durand, A., El, S. N., Grauwet, T., Heerup, C., Heredia, A., Infantes Garcia, M. R., Jungnickel, C. & 26 others, , 2021, In: Journal of Functional Foods. 82, 104497.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile31 Citations (Scopus)32 Downloads (Pure) -
In vitro and in vivo comparison of microcontainers and microspheres for oral drug delivery
Christfort, J. F., Strindberg, S., Al-khalili, S., Bar-Shalom, D., Boisen, A., Nielsen, L. H. & Mullertz, A., 2021, In: International Journal of Pharmaceutics. 600, 9 p., 120516.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile7 Citations (Scopus)20 Downloads (Pure) -
Oligonucleotide Delivery across the Caco-2 Monolayer: The Design and Evaluation of Self-Emulsifying Drug Delivery Systems (SEDDS)
Kubackova, J., Holas, O., Zbytovska, J., Vranikova, B., Zeng, G., Pavek, P. & Mullertz, A., Apr 2021, In: Pharmaceutics. 13, 4, 27 p., 459.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile11 Citations (Scopus)77 Downloads (Pure) -
Predicting Oral Absorption of fenofibrate in Lipid-Based Drug Delivery Systems by Combining In Vitro Lipolysis with the Mucus-PVPA Permeability Model
Falavigna, M., Klitgaard, M., Berthelsen, R., Muellertz, A. & Flaten, G. E., 2021, In: Journal of Pharmaceutical Sciences. 110, 1, p. 208-216 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile13 Citations (Scopus)33 Downloads (Pure) -
The Influence of Solidification on the in vitro Solubilisation of Blonanserin Loaded Supersaturated Lipid-Based Oral Formulations
Moller, A., Schultz, H. B., Meola, T. R., Muellertz, A. & Prestidge, C. A., 2021, In: European Journal of Pharmaceutical Sciences. 157, 10 p., 105640.Research output: Contribution to journal › Journal article › Research › peer-review
4 Citations (Scopus)