Axel Kornerup Hansen

Research output

Research output per year 1997 2000 2002 2003 2005 2006 2007 2009 2010 2011 2012 2013 2014 2015 2019 2020 2022 2023 2024

• 6187 Citations
• 240 Journal article
• 26 Conference abstract for conference
• 18 Poster
• 9 Book chapter
• 47 More
  • 9 Article in proceedings
  • 9 Review
  • 8 Paper
  • 7 Conference abstract in journal
  • 5 Conference abstract in proceedings
  • 4 Book
  • 2 Letter
  • 1 Conference article
  • 1 Editorial
  • 1 Patent

Research output per year

Research output per year

Search results

• 2024

  Assessment of the Inflammatory Effects of Gut Microbiota from Human Twins Discordant for Ulcerative Colitis on Germ-free Mice

  Knudsen, L. A., Zachariassen, L. SF., Strube, M. L., Havelund, J. F., Pilecki, B., Nexoe, A. B., Møller, F. T., Sørensen, S. B., Marcussen, N., Faergeman, N. J., Franke, A., Bang, C., Holmskov, U., Hansen, A. K. & Andersen, V., 2024, In: Comparative Medicine. 74, 2, p. 55-69

  Research output: Contribution to journal › Journal article › Research › peer-review

• High fat diet is associated with gut microbiota dysbiosis and decreased gut microbial derived metabolites related to metabolic health in young Göttingen Minipigs

  Lützhøft, D. O., Bækgård, C., Wimborne, E., Straarup, E. M., Pedersen, K. M., Swann, J. R., Pedersen, H. D., Kristensen, K., Morgills, L., Nielsen, D. S., Hansen, A. K., Bracken, M. K., Cirera, S. & Christoffersen, B. Ø., 2024, In: PLoS ONE. 19, 3, 27 p., e0298602.

  Research output: Contribution to journal › Journal article › Research › peer-review

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• Induction of CD8⁺ immune memory and enhanced inflammation in a skin inflammation model through pre-immunization with inactivated pathogens

  Falkenberg, C., Bartholdy, C., Koch, J., Toft, MF., Skov, S., Hansen, C. H. F. & Hansen, AK., 2024, In: Clinical and Translational Science. 17, 1, 14 p., e13697.

  Research output: Contribution to journal › Journal article › Research › peer-review

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• Low-gainer diet-induced obese microbiota transplanted mice exhibit increased fighting

  Junker Mentzel, C. M., Hui, Y., Hammerich, T. M. S., Klug-Dambmann, M., Liu, Y., Zachariassen, L. F., Hansen, L. H., Aslampaloglou, A., Kiersgaard, M., Nielsen, D. S., Hansen, A. K. & Krych, L., 2024, In: Clinical and Translational Science. 17, 9, 12 p., e13906.

  Research output: Contribution to journal › Journal article › Research › peer-review

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• Overcoming donor variability and risks associated with fecal microbiota transplants through bacteriophage-mediated treatments

  Rasmussen, T. S., Mao, X., Forster, S., Larsen, S. B., Von Münchow, A., Tranæs, K. D., Brunse, A., Larsen, F., Mejia, J. L. C., Adamberg, S., Hansen, A. K., Adamberg, K., Hansen, C. H. F. & Nielsen, D. S., 2024, In: Microbiome. 12, 24 p., 119.

  Research output: Contribution to journal › Journal article › Research › peer-review

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  1 Citation (Scopus)

  7 Downloads (Pure)

• Probiotic treatment with viable α-galactosylceramide-producing Bacteroides fragilis reduces diabetes incidence in female nonobese diabetic mice

  Hansen, C. H. F., Jozipovic, D., Zachariassen, L. F., Nielsen, D. S., Hansen, A. K. & Buschard, K., 2024, In: Journal of Diabetes. 16, 8, 14 p., e13593.

  Research output: Contribution to journal › Journal article › Research › peer-review

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• Transfer of modified gut viromes improves symptoms associated with metabolic syndrome in obese male mice

  Mao, X., Larsen, S. B., Zachariassen, L. S. F., Brunse, A., Adamberg, S., Mejia, J. L. C., Larsen, F., Adamberg, K., Nielsen, D. S., Hansen, A. K., Hansen, C. H. F. & Rasmussen, T. S., 2024, In: Nature Communications. 15, 19 p., 4704.

  Research output: Contribution to journal › Journal article › Research › peer-review

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  1 Citation (Scopus)

  7 Downloads (Pure)
• 2023

  CRISPR-Cas provides limited phage immunity to a prevalent gut bacterium in gnotobiotic mice

  Rasmussen, T. S., Koefoed, A. K., Deng, L., Muhammed, M. K., Rousseau, G. M., Kot, W., Sprotte, S., Neve, H., Franz, C. M. A. P., Hansen, A. K., Vogensen, F. K., Moineau, S. & Nielsen, D. S., 2023, In: ISME Journal. 17, p. 432–442

  Research output: Contribution to journal › Journal article › Research › peer-review

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  46 Downloads (Pure)

• Effect of Systemic Administration of CD4⁺ T cells and Local Administration of T-cell Stimulants on T-cell Activity in Psoriatic Skin Xenografts on NOG Mice

  Christensen, P. KF., Hansen, A. K., Skov, S., Larsen, J., Høyer-Hansen, M. H. & Koch, J., 2023, In: Comparative Medicine. 73, 4, p. 285-293

  Research output: Contribution to journal › Journal article › Research › peer-review

• Fecal virome transfer improves proliferation of commensal gut Akkermansia muciniphila and unexpectedly enhances the fertility rate in laboratory mice

  Rasmussen, T. S., Mentzel, C. M. J., Danielsen, M. R., Jakobsen, R. R., Zachariassen, L. S. F., Castro Mejia, J. L., Brunse, A., Hansen, L. H., Hansen, C. H. F., Hansen, A. K. & Nielsen, D. S., 2023, In: Gut Microbes. 15, 1, 21 p., 2208504.

  Research output: Contribution to journal › Journal article › Research › peer-review

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  11 Citations (Scopus)

  46 Downloads (Pure)

• Imiquimod induces skin inflammation in humanized BRGSF mice with limited human immune cell activity

  Christensen, P. K. F., Hansen, A. K., Skov, S., Martel, B. C., Larsen, J., Høyer-Hansen, M. H. & Koch, J., 2023, In: PLoS ONE. 18, e0281005.

  Research output: Contribution to journal › Journal article › Research › peer-review

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  1 Citation (Scopus)

  18 Downloads (Pure)

• Impaired Abcb1a function and red meat in a translational colitis mouse model induces inflammation and alters microbiota composition

  Stensballe, A., Bennike, T. B., Ravn-Haren, G., Mortensen, A., Aboo, C., Knudsen, L. A., Rühlemann, M. C., Birkelund, S., Bang, C., Franke, A., Vogel, U., Hansen, A. K. & Andersen, V., 2023, In: Frontiers in Medicine. 10, 1200317.

  Research output: Contribution to journal › Journal article › Research › peer-review

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• Inulin Supplementation Modulates the Hepatic Transcriptome, Metabolome, and Ferritin Content in Ovariectomized Rats

  Zhao, X., He, W., Jakobsen, L. M. A., Zachariassen, L. F., Hansen, A. K., Rasmussen, M. K. & Bertram, H. C., 2023, In: Molecular Nutrition and Food Research. 67, 23, 10 p., 2300372.

  Research output: Contribution to journal › Journal article › Research › peer-review

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  2 Citations (Scopus)

  8 Downloads (Pure)

• Investigating the Crime Scene—Molecular Signatures in Inflammatory Bowel Disease

  Andersen, V., Bennike, T. B., Bang, C., Rioux, J. D., Hébert-Milette, I., Sato, T., Hansen, A. K. & Nielsen, O. H., 2023, In: International Journal of Molecular Sciences. 24, 13, 11217.

  Research output: Contribution to journal › Review › Research › peer-review

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  3 Citations (Scopus)

  16 Downloads (Pure)

• Maternal antibiotic exposure increases total islet number and volume in the neonatal pancreas and reduces HbA1c and insulitis in adult female non-obese diabetic mice

  Hansen, C. H. F., Haupt-Jorgensen, M., Buschard, K., Pakkenberg, B., Krych, L. & Hansen, A. K., 2023, In: Clinical and Translational Discovery. 3, 2, 13 p., e188.

  Research output: Contribution to journal › Journal article › Research › peer-review

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  1 Citation (Scopus)

  23 Downloads (Pure)

• Oligosaccharide feed supplementation reduces plasma insulin in geldings with Equine Metabolic Syndrome

  Von Münchow, A., Torp Yttergren, S., Jakobsen, R. R., Luthersson, N., Hansen, A. K. & Lindenberg, F., 2023, In: Frontiers in Microbiomes. 2, p. 1194705 15 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

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  10 Downloads (Pure)

• Sustaining the T-cell activity in xenografted psoriasis skin

  Christensen, P. K. F., Hansen, A. K., Skov, S., Engkilde, K., Larsen, J., Høyer-Hansen, M. H. & Koch, J., 2023, In: PLoS ONE. 18, e0278390.

  Research output: Contribution to journal › Journal article › Research › peer-review

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  4 Citations (Scopus)

  13 Downloads (Pure)

• The impact of bacterial exposure in early life on lung surfactant gene expression, function and respiratory rate in germ-free mice

  Barfod, K. K., Lui, J. C., Hansen, S. S. K., Sengupta, S., Zachariassen, L. S. F., Hansen, A. K. & Sørli, J. B., 2023, In: Frontiers in Microbiomes. 2, 12 p., 1085508.

  Research output: Contribution to journal › Journal article › Research › peer-review

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• The intestinal permeability marker FITC-dextran 4kDa should be dosed according to lean body mass in obese mice

  Voetmann, L. M., Rolin, B., Kirk, R. K., Pyke, C. & Hansen, A. K., 2023, In: Nutrition and Diabetes. 13, 1.

  Research output: Contribution to journal › Journal article › Research › peer-review

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• 2022

  Controlling the uncontrolled variation in the diet induced obese mouse by microbiomic characterization

  Bondarenko, V., Lokke, C. R., Dobrowolski, P., Mentzel, C. J., Castro-Mejia, J. L., Hansen, C. H. F., Sorensen, D. B., Nielsen, D. S., Krych, L. & Hansen, A. K., 2022, In: Scientific Reports. 12, 12 p., 13767.

  Research output: Contribution to journal › Journal article › Research › peer-review

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  2 Citations (Scopus)

  40 Downloads (Pure)

• Dual nuclear magnetic resonance for probing intrinsic bone structure and a potential gut–bone axis in ovariectomized rats

  He, W., Jakobsen, L. M. A., Zachariassen, L. F., Hansen, A. K., Andersen, H. J. & Bertram, H. C., 2022, In: Magnetic Resonance in Chemistry. 60, 7, p. 651-658

  Research output: Contribution to journal › Journal article › Research › peer-review

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• Dyreforsøg

  Translated title of the contribution: Offal, feed and rendering plantsHansen, A. K. & Sørensen, D. B., 2022, Veterinær Retsmedicin. Agger, J. F. G., Houe, H. & Otten, N. D. (eds.). 1 ed. Frederiksberg, Denmark: Biofolia

  Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Education

• Effect of gluten-free diet and antibiotics on murine gut microbiota and immune response to tetanus vaccination

  Kihl, P., Krych, L., Deng, L., Hansen, L. H., Buschard, K., Skov, S., Nielsen, D. S. & Hansen, A. K., 2022, In: Plos One. 17, 4, 21 p., e0266719.

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• Effects of Calcium Source, Inulin, and Lactose on Gut-Bone Associations in an Ovarierectomized Rat Model

  He, W., Xie, Z., Thøgersen, R., Rasmussen, M. K., Zachariassen, L. F., Jørgensen, N. R., Nørgaard, J. V., Andersen, H. J., Nielsen, D. S., Hansen, A. K. & Bertram, H. C., 2022, In: Molecular Nutrition and Food Research. 66, 8, 12 p., 2100883.

  Research output: Contribution to journal › Journal article › Research › peer-review

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• Gluten-free diet reduces autoimmune diabetes mellitus in mice across multiple generations in a microbiota-independent manner

  Hansen, C. H. F., Larsen, C. S., Zachariassen, L. F., Mentzel, C. M. J., Laigaard, A., Krych, L., Nielsen, D. S., Gobbi, A., Haupt-Jorgensen, M., Buschard, K. & Hansen, A. K., 2022, In: Journal of Autoimmunity. 127, 102795.

  Research output: Contribution to journal › Journal article › Research › peer-review

• Ind- og udførsel af levende dyr

  Translated title of the contribution: Import and export of live animalsNielsen, S. S. & Hansen, A. K., 2022, Veterinær Retsmedicin. Agger, J. F. G., Houe, H. & Otten, N. D. (eds.). 1 ed. Frederiksberg, Denmark: Biofolia

  Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Education

• In vitro cell cultures of Brunner's glands from male mouse to study GLP-1 receptor function

  Voetmann, L. M., Underwood, C. R., Rolin, B., Hansen, A. K., Kirk, R. K., Pyke, C., Knudsen, L. B. & Frederiksen, K. S., 2022, In: American journal of physiology. Cell physiology. 322, 6, p. C1260-C1269

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  1 Citation (Scopus)

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• Marked gut microbiota dysbiosis and increased imidazole propionate are associated with a NASH Göttingen Minipig model

  Lützhøft, D. O., Sinioja, T., Christoffersen, B., Jakobsen, R. R., Geng, D., Ahmad, H. F. B., Straarup, E. M., Pedersen, K. M., Kot, W., Pedersen, H. D., Cirera, S., Hyötyläinen, T., Nielsen, D. S. & Hansen, A. K., 2022, In: BMC Microbiology. 22, 1, 287.

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• Oligosaccharide equine feed supplement, Immulix, has minor impact on vaccine responses in mice

  Henriksen, I. W., Mejia, J. L. C., Mentzel, C. M. J., Lindenberg, F. & Hansen, A. K., 2022, In: Scientific Reports. 12, 582.

  Research output: Contribution to journal › Journal article › Research › peer-review

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• Pre-immunization with inactivated pathogens recapitulates adult human immune traits in laboratory mice

  Falkenberg, C., Toft, M. F., Skov, S. & Hansen, A. K., 2022, In: Laboratory Animals. 56, S1, p. 25-25 S2A5.3.

  Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

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• Yogurt Benefits Bone Mineralization in Ovariectomized Rats with Concomitant Modulation of the Gut Microbiome

  He, W., Xie, Z., Wittig, N. K., Zachariassen, L. F., Andersen, A., Andersen, H. J., Birkedal, H., Nielsen, D. S., Hansen, A. K. & Bertram, H. C., 2022, In: Molecular Nutrition and Food Research. 66, 20, 10 p., 2200174.

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  4 Citations (Scopus)

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• 2021

  Administration of bovine milk oligosaccharide to weaning gnotobiotic mice inoculated with a simplified infant type microbiota

  Jakobsen, L. M. A., Sundekilde, U. K., Andersen, H. J., Kot, W., Mejia, J. L. C., Nielsen, D. S., Hansen, A. K. & Bertram, H. C., 2021, In: Microorganisms. 9, 5, 1003.

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• An Oligosaccharide Rich Diet Increases Akkermansia spp. Bacteria in the Equine Microbiota

  Lindenberg, F. C., Lützhøft, D. O., Krych, L., Fielden, J., Kot, W., Frøkiær, H., van Galen, G., Nielsen, D. S. & Hansen, A. K., 2021, In: Frontiers in Microbiology. 12, 666039.

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• Delayed Gut Colonization Shapes Future Allergic Responses in a Murine Model of Atopic Dermatitis

  Arildsen, A. W., Zachariassen, L. F., Krych, L., Hansen, A. K. & Hansen, C. H. F., 2021, In: Frontiers in Immunology. 12, 650621.

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  10 Citations (Scopus)

  38 Downloads (Pure)

• Effects of delivery mode on behavior in mouse offspring

  Zachariassen, L. F., Sørensen, D. B., Krych, L., Hansen, A. K. & Hansen, C. H. F., 2021, In: Physiology and Behavior. 230, 113285.

  Research output: Contribution to journal › Journal article › Research › peer-review
  7 Citations (Scopus)

• Inter-vendor variance of enteric eukaryotic DNA viruses in specific pathogen free C57BL/6N mice

  Rasmussen, T. S., Jakobsen, R. R., Castro-Mejía, J. L., Kot, W., Thomsen, A. R., Vogensen, F. K., Nielsen, D. S. & Hansen, A. K., 2021, In: Research in Veterinary Science. 136, p. 1-5 5 p.

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• Partial substitution of meat with insect (Alphitobius diaperinus) in a carnivore diet changes the gut microbiome and metabolome of healthy rats

  Lanng, S. K., Zhang, Y., Christensen, K. R., Hansen, A. K., Nielsen, D. S., Kot, W. & Bertram, H. C., 2021, In: Foods. 10, 8, 14 p., 1814.

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• Systems-wide effects of short-term feed deprivation in obese mice

  Andersen, D., Roager, H. M., Zhang, L., Moll, J. M., Frandsen, H. L., Danneskiold-Samsøe, N. B., Hansen, A. K., Kristiansen, K., Licht, T. R. & Brix, S., 2021, In: Scientific Reports. 11, 11 p., 5716.

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• The microbiome and rodent models of immune mediated diseases

  Hansen, A. K. & Hansen, C. H. F., 2021, In: Mammalian Genome. 32, p. 251–262

  Research output: Contribution to journal › Review › Research › peer-review

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  10 Citations (Scopus)
• 2020

  A Humanized Diet Profile May Facilitate Colonization and Immune Stimulation in Human Microbiota-Colonized Mice

  Moreno-Indias, I., Lundberg, R., Krych, L., Metzdorff, S. B., Kot, W., Sørensen, D. B., Nielsen, D. S., Hansen, C. H. F. & Hansen, A. K., 2020, In: Frontiers in Microbiology. 11, 15 p., 1336.

  Research output: Contribution to journal › Journal article › Research › peer-review

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  10 Citations (Scopus)

  93 Downloads (Pure)

• Betamethasone Treatment for Atopic Dermatitis in Gut Microbiota Transplanted Mice

  Debes, K. P., Evdina, N. A., Laigaard, A., Larsen, J. M., Zachariassen, L. F., Hansen, C. H. F. & Hansen, A. K., 2020, In: Comparative Medicine. 70, 1, p. 6-15 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

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  4 Citations (Scopus)

• C57BL/6J substrain differences in response to high-fat diet intervention

  Siersbæk, M. S., Ditzel, N., Hejbøl, E. K., Præstholm, S. M., Markussen, L. K., Avolio, F., Li, L., Lehtonen, L., Hansen, A. K., Schrøder, H. D., Krych, L., Mandrup, S., Langhorn, L., Bollen, P. & Grøntved, L., 2020, In: Scientific Reports. 10, 1, 15 p., 14052.

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  45 Citations (Scopus)

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• Dietary prebiotics promote intestinal Prevotella in association with a low-responding phenotype in a murine oxazolone-induced model of atopic dermatitis

  Laigaard, A., Krych, L., Zachariassen, L. F., Ellegaard-Jensen, L., Nielsen, D. S., Hansen, A. K. & Hansen, C. H. F., 2020, In: Scientific Reports. 10, 1, 11 p., 21204.

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  2 Citations (Scopus)

  36 Downloads (Pure)

• Faecal virome transplantation decreases symptoms of type 2 diabetes and obesity in a murine model

  Rasmussen, T. S., Mentzel, C. M. J., Kot, W., Castro-Mejiá, J. L., Zuffa, S., Swann, J. R., Hansen, L. H., Vogensen, F. K., Hansen, A. K. & Nielsen, D. S., 2020, In: Gut. 69, 12, p. 2122-2130 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  37 Citations (Scopus)

• Human microbiota-transplanted C57BL/6 mice and offspring display reduced establishment of key bacteria and reduced immune stimulation compared to mouse microbiota-transplantation

  Lundberg, R., Toft, M. F., Metzdorff, S. B., Hansen, C. H. F., Licht, T. R., Bahl, M. I. & Hansen, A. K., 2020, In: Scientific Reports. 10, 16 p., 7805.

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• Initial joint bleed volume in a delayed on-demand treatment setup correlates with subsequent synovial changes in hemophilic mice

  Vøls, K. K., Kjelgaard-Hansen, M., Ley, C. D., Hansen, A. K. & Petersen, M., 2020, In: Animal models and experimental medicine. 3, 2, p. 160-168 9 p.

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• Inulin and milk mineral fortification of a pork sausage exhibits distinct effects on the microbiome and biochemical activity in the gut of healthy rats

  Thøgersen, R., Castro-Mejía, J. L., Sundekilde, U. K., H. Hansen, L., Gray, N., Kuhnle, G., Rye Jørgensen, N., Hansen, A. K., Nielsen, D. S. & Bertram, H. C., 2020, In: Food Chemistry. 331, 10 p., 127291.

  Research output: Contribution to journal › Journal article › Research › peer-review
  12 Citations (Scopus)

• Inulin-fortification of a processed meat product attenuates formation of nitroso compounds in the gut of healthy rats

  Thøgersen, R., Gray, N., Kuhnle, G., Van Hecke, T., De Smet, S., Young, J. F., Sundekilde, U. K., Hansen, A. K. & Bertram, H. C., 2020, In: Food Chemistry. 302, 7 p., 125339.

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  22 Citations (Scopus)

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• In vivo fluorescence molecular tomography of induced haemarthrosis in haemophilic mice: link between bleeding characteristics and development of bone pathology

  Vols, K. K., Kjelgaard-Hansen, M., Ley, C. D., Hansen, A. K. & Petersen, M., 14 Apr 2020, In: BMC Musculoskeletal Disorders. 21, 1, 10 p., 241.

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  3 Citations (Scopus)

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• Proteoglycan synthesis rate as a novel method to measure blood-induced cartilage degeneration in non-haemophilic and haemophilic rats

  Pulles, A. E., Vøls, K. K., Christensen, K. R., Coeleveld, K., Hansen, A. K., van Vulpen, L. F. D., Petersen, M., Mastbergen, S. C., Roepstorff, K., Schutgens, R. E. G., Kjelgaard-Hansen, M. & Lafeber, F. P. J. G., 2020, In: Haemophilia. 26, 3, p. e88-e96

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  2 Citations (Scopus)

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