Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Structural insights into the inhibition of glycine reuptake
Shahsavar, A., Stohler, P., Bourenkov, G., Zimmermann, I., Siegrist, M., Guba, W., Pinard, E., Sinning, S., Seeger, M. A., Schneider, T. R., Dawson, R. J. P. & Nissen, P., 2021, In: Nature. 591, p. 677–681Research output: Contribution to journal › Journal article › Research › peer-review
91 Citations (Scopus) -
Structure of the human dopamine transporter in complex with cocaine
Nielsen, J. C., Salomon, K., Kalenderoglou, I. E., Bargmeyer, S., Pape, T., Shahsavar, A. & Loland, C. J., 2024, In: Nature. 632, 8025, p. 678-685 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile40 Citations (Scopus)94 Downloads (Pure) -
Cryo-EM structure of the dopamine transporter with a novel atypical non-competitive inhibitor bound to the orthosteric site
Pedersen, C. N., Yang, F., Ita, S., Xu, Y., Akunuri, R., Trampari, S., Neumann, C. M. T., Desdorf, L. M., Schiøtt, B., Salvino, J. M., Mortensen, O. V., Nissen, P. & Shahsavar, A., 2024, In: Journal of Neurochemistry. 168, 9, p. 2043-2055Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile12 Citations (Scopus)38 Downloads (Pure) -
GABA transport cycle: beyond a GAT feeling
Shahsavar, A. & Wellendorph, P., 2023, In: Nature Structural and Molecular Biology. 30, p. pages863–865Research output: Contribution to journal › Comment/debate › Research › peer-review
5 Citations (Scopus) -
Crystal structures of a pentameric ligand-gated ion channel provide a mechanism for activation.
Sauguet, L., Shahsavar, A., Poitevin, F., Huon, C., Menny, A., Nemecz, À., Haouz, A., Changeux, J.-P., Corringer, P.-J. & Delarue, M., 22 Nov 2013, In: PNAS Early Edition.Research output: Contribution to journal › Journal article › Research › peer-review
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Crystal Structure of Lymnaea stagnalis AChBP Complexed with the Potent nAChR Antagonist DHßE Suggests a Unique Mode of Antagonism
Shahsavar, A., Kastrup, J. S., Nielsen, E. Ø., Kristensen, J. L., Gajhede, M. & Balle, T., 2012, In: P L o S One. 7, 8, p. e40757Research output: Contribution to journal › Journal article › Research › peer-review
41 Citations (Scopus) -
A reversible allosteric inhibitor of GlyT2 for neuropathic pain without on-target side effects
Cantwell Chater, R. P., Peiser-Oliver, J., Pati, T. K., Quinn, A. S., Lotsaris, I., Frangos, Z. J., Anderson, K. E., Tischer, A. E., Williams-Noonan, B. J., Aubrey, K. R., O’Mara, M. L., Michaelides, M., Mohammadi, S. A., Cioffi, C. L., Vandenberg, R. J. & Shahsavar, A., 2026, In: Nature Communications. 17, 1, 19 p., 2828.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile1 Citation (Scopus)1 Downloads (Pure) -
Identification of Non-competitive and Reversible Inhibitors of Glycine Transporter 2: A Promising Non-opioid Therapeutic Strategy for Neuropathic Pain
Cioffi, C. L., Pati, T. K., Lotsaris, I., Jayakumar, S., Peiser-Oliver, J., Mahesh, G., Chater, R. P. C., Jayaraman, A., Frangos, Z. J., Suleria, K., Evans, S., Kuppusamy, R., Raja, A., Muthuraman, P., Mulmule, J., Mishra, S., Singh, S., Palanimuthu, A., Michaelides, M. & Shahsavar, A. & 2 others, , 2026, (E-pub ahead of print) In: Journal of Medicinal Chemistry. 37 p.Research output: Contribution to journal › Journal article › Research › peer-review