Personal profile
CV
Education
1998 Ph.D., Molecular Biology, University of Copenhagen
1994 M.Sc., Molecular Biology, University of Copenhagen
Career
2007- Associate Professor, BRIC and Copenhagen University Hospital
2003-2007 Group leader, Copenhagen University Hospital
2001-2003 Senior Researcher, Copenhagen University Hospital
1999-2001 Postdoc, Copenhagen University Hospital
1998-1999 Postdoc, University of Copenhagen
Primary fields of research
HematopoiesisMouse genetics
Cancer
Current research
C/EBPalpha in normal and malignant hematopoiesisHematopoetic and leukemic stem cells
Nonsense-mediated mRNA in mammalian development
Fields of interest
HematopoiesisMouse genetics
Cancer
Collaborations and top research areas from the last five years
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A non-conditioned bone marrow transplantation mouse model to study clonal hematopoiesis and myeloid malignancies
Bentivegna, S., Almosailleakh, M., Zhao, L.-P., Schuster, M. B., Benquet, S., Balhuizen, A., Munch-Petersen, H. F., Sjö, L. D., Andersen, M. H., Dulphy, N., Porse, B. & Grønbæk, K., 2025, In: Experimental Hematology and Oncology. 14, 1, 6 p., 10.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile22 Downloads (Pure) -
Mapping early human blood cell differentiation using single-cell proteomics and transcriptomics
Furtwängler, B., Üresin, N., Richter, S., Schuster, M. B., Barmpouri, D., Holze, H., Wenzel, A., Grønbæk, K., Theilgaard-Mönch, K., Theis, F. J., Schoof, E. M. & Porse, B. T., 2025, In: Science. 390, 6770, 21 p., eadr8785.Research output: Contribution to journal › Journal article › Research › peer-review
2 Citations (Scopus) -
Mutant CEBPA promotes tolerance to inflammatory stress through deficient AP-1 activation
Cadefau-Fabregat, M., Martínez-Cebrián, G., Lorenzi, L., Weiss, F. D., Frank, A. K., Castelló-García, J. M., Julià-Vilella, E., Gámez-García, A., Yera, L., de Castro, C. P. M., Wang, Y. F., Meissner, F., Vaquero, A., Merkenschlager, M., Porse, B. T. & Cuartero, S., 2025, In: Nature Communications. 16, 1, 19 p., 3492.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile3 Citations (Scopus)10 Downloads (Pure) -
Overlapping DNA methylation changes in enhancers in clonal cytopenia of undetermined significance and myelodysplastic neoplasm patients with TET2, IDH2, or DNMT3A mutations
Kaastrup, K., Tulstrup, M., Hansen, J. W., Schöllkopf, C., Raaschou-Jensen, K., Ørskov, A. D., Porse, B., Jones, P. A., Weischenfeldt, J., Gillberg, L. & Grønbæk, K., 2025, In: Haematologica. 110, 5, p. 1164-1169Research output: Contribution to journal › Letter › peer-review
Open AccessFile1 Citation (Scopus)6 Downloads (Pure) -
Quantitative Label-Free Single-Cell Proteomics on the Orbitrap Astral MS
Petrosius, V., Aragon-Fernandez, P., Arrey, T. N., Woessmann, J., Uresin, N., de Boer, B., Su, J., Furtwangler, B., Stewart, H., Denisov, E., Petzoldt, J., Peterson, A. C., Hock, C., Damoc, E., Makarov, A., Zabrouskov, V., Porse, B. T. & Schoof, E. M., 2025, In: Molecular & Cellular Proteomics. 24, 6, 13 p., 100982.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile4 Citations (Scopus)6 Downloads (Pure) -
A proinflammatory stem cell niche drives myelofibrosis through a targetable galectin-1 axis
Li, R., Colombo, M., Wang, G., Rodriguez-Romera, A., Benlabiod, C., Jooss, N. J., O'Sullivan, J., Brierley, C. K., Clark, S. A., Pérez Sáez, J. M., Fernández, P. A., Schoof, E. M., Porse, B., Meng, Y., Khan, A. O., Wen, S., Dong, P., Zhou, W., Sousos, N. & Murphy, L. & 17 others, , 2024, In: Science Translational Medicine. 16, 768, 16 p., eadj7552.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile12 Citations (Scopus)2 Downloads (Pure) -
BloodSpot 3.0: a database of gene and protein expression data in normal and malignant haematopoiesis
Gíslason, M. H., Demircan, G. S., Prachar, M., Furtwängler, B., Schwaller, J., Schoof, E., Porse, B., Rapin, N. & Bagger, F., 2024, In: Nucleic acids symposium series. 52, D1, p. D1138–D1142 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile35 Citations (Scopus)36 Downloads (Pure) -
Increased myeloid-derived suppressor cell activation in clonal cytopenia of undetermined significance and low-risk myelodysplastic syndrome
Bentivegna, S., Côme, C., Porse, B., Andersen, M. H. & Grønbæk, K., 2024, In: British Journal of Haematology. 205, 3, p. 1220-1224 5 p.Research output: Contribution to journal › Letter › peer-review