Research output per year
Research output per year
Personal profile
Short presentation
My main research focus is in vitro cell models of the blood-brain barrier. This includes subprojects investigating 1) the usability of P-gp expressing cell line as a surrogate model of the blood-brain barrier, 2) the effect of hypoxic conditions on cultured brain capillary endothelial cells 3) modeling the healthy and diseased brain endothelium using stem cell based in vitro models and 4) drug permeation across the blood-brain barrier.
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Research output
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The putative proton-coupled organic cation antiporter is involved in uptake of triptans into human brain capillary endothelial cells
Svane, N. I., Pedersen, A. B. V., Rodenberg, A., Ozgür, B., Saaby, L., Bundgaard, C., Kristensen, M., Tfelt-Hansen, P. & Larsen, B. B., 2024, In: Fluids and Barriers of the CNS. 21, 19 p., 39.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile3 Citations (Scopus)13 Downloads (Pure) -
Characterization of an iPSC-based barrier model for blood-brain barrier investigations using the SBAD0201 stem cell line
Ozgür, B., Puris, E., Brachner, A., Appelt-Menzel, A., Oerter, S., Balzer, V., Holst, M. R., Christiansen, R. F., Hyldig, K., Buckley, S. T., Kristensen, M., Auriola, S., Jensen, A., Fricker, G., Nielsen, M. S., Neuhaus, W. & Brodin, B., 2023, In: Fluids and Barriers of the CNS. 20, 1, 15 p., 96.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile28 Downloads (Pure) -
Subcellular trafficking and transcytosis efficacy of different receptor types for therapeutic antibody delivery at the blood‒brain barrier
Holst, M. R., de Wit, N. M., Ozgür, B., Brachner, A., Hyldig, K., Appelt-Menzel, A., Sleven, H., Cader, Z., de Vries, H. E., Neuhaus, W., Jensen, A., Brodin, B. & Nielsen, M. S., 2023, In: Fluids and Barriers of the CNS. 20, 1, 17 p., 82.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile2 Citations (Scopus)18 Downloads (Pure) -
En af hjernens forsvarsmure: Blod-hjerne-barrieren
Ozgür, B., 2022, In: Pharma. 2022, 4, p. 15-17Research output: Contribution to journal › Contribution to newspaper - Newspaper article › Communication
Open AccessFile26 Downloads (Pure) -
Highly cationic cell-penetrating peptides affect the barrier integrity and facilitates mannitol permeation in a human stem cell-based blood-brain barrier model
Frøslev, P., Franzyk, H., Ozgür, B., Larsen, B. B. & Kristensen, M., 2022, In: European Journal of Pharmaceutical Sciences. 168, 10 p., 106054.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile117 Downloads (Pure) -
Hypoxia increases expression of selected blood–brain barrier transporters GLUT-1, P-gp, SLC7A5 and TFRC, while maintaining barrier integrity, in brain capillary endothelial monolayers
Ozgür, B., Helms, H. C. C., Tornabene, E. & Larsen, B. B., 2022, In: Fluids and Barriers of the CNS. 19, 1, 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile24 Downloads (Pure) -
The Cell-Penetrating Peptide Tat Facilitates Effective Internalization of PSD-95 Inhibitors Into Blood–Brain Barrier Endothelial Cells but less Efficient Permeation Across the Blood–Brain Barrier In Vitro and In Vivo
Lisa Al Humaidan, E., Lund Pedersen, S., Burkhart, A., Laurfelt Munch Rasmussen, C., Moos, T., Fuchs, P., Alves Fernandes, E. F., Ozgür, B., Strømgaard, K., Bach, A., Larsen, B. B. & Kristensen, M., 2022, In: Frontiers in Drug Delivery - CNS Drug Delivery. 2, 17 p., 854703.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile82 Downloads (Pure) -
Human induced pluripotent stem cells (BIONi010-C) generate tight cell monolayers with blood-brain barrier traits and functional expression of large neutral amino acid transporter 1 (SLC7A5)
Goldeman, C., Andersen, M., Al-Robai, A., Buchholtz, T., Svane, N., Ozgür, B., Holst, B., Shusta, E., Hall, V. J., Saaby, L., Hyttel, P. & Brodin, B., 2021, In: European Journal of Pharmaceutical Sciences. 156, 14 p., 105577.Research output: Contribution to journal › Journal article › Research › peer-review
14 Citations (Scopus)