Burak Ozgür

Search results

• 2024

  The putative proton-coupled organic cation antiporter is involved in uptake of triptans into human brain capillary endothelial cells

  Svane, N. I., Pedersen, A. B. V., Rodenberg, A., Ozgür, B., Saaby, L., Bundgaard, C., Kristensen, M., Tfelt-Hansen, P. & Larsen, B. B., 2024, In: Fluids and Barriers of the CNS. 21, 19 p., 39.

  Research output: Contribution to journal › Journal article › Research › peer-review

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  3 Citations (Scopus)

  13 Downloads (Pure)
• 2023

  Characterization of an iPSC-based barrier model for blood-brain barrier investigations using the SBAD0201 stem cell line

  Ozgür, B., Puris, E., Brachner, A., Appelt-Menzel, A., Oerter, S., Balzer, V., Holst, M. R., Christiansen, R. F., Hyldig, K., Buckley, S. T., Kristensen, M., Auriola, S., Jensen, A., Fricker, G., Nielsen, M. S., Neuhaus, W. & Brodin, B., 2023, In: Fluids and Barriers of the CNS. 20, 1, 15 p., 96.

  Research output: Contribution to journal › Journal article › Research › peer-review

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• Subcellular trafficking and transcytosis efficacy of different receptor types for therapeutic antibody delivery at the blood‒brain barrier

  Holst, M. R., de Wit, N. M., Ozgür, B., Brachner, A., Hyldig, K., Appelt-Menzel, A., Sleven, H., Cader, Z., de Vries, H. E., Neuhaus, W., Jensen, A., Brodin, B. & Nielsen, M. S., 2023, In: Fluids and Barriers of the CNS. 20, 1, 17 p., 82.

  Research output: Contribution to journal › Journal article › Research › peer-review

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  2 Citations (Scopus)

  18 Downloads (Pure)
• 2022

  En af hjernens forsvarsmure: Blod-hjerne-barrieren

  Ozgür, B., 2022, In: Pharma. 2022, 4, p. 15-17

  Research output: Contribution to journal › Contribution to newspaper - Newspaper article › Communication

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  26 Downloads (Pure)

• Highly cationic cell-penetrating peptides affect the barrier integrity and facilitates mannitol permeation in a human stem cell-based blood-brain barrier model

  Frøslev, P., Franzyk, H., Ozgür, B., Larsen, B. B. & Kristensen, M., 2022, In: European Journal of Pharmaceutical Sciences. 168, 10 p., 106054.

  Research output: Contribution to journal › Journal article › Research › peer-review

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• Hypoxia increases expression of selected blood–brain barrier transporters GLUT-1, P-gp, SLC7A5 and TFRC, while maintaining barrier integrity, in brain capillary endothelial monolayers

  Ozgür, B., Helms, H. C. C., Tornabene, E. & Larsen, B. B., 2022, In: Fluids and Barriers of the CNS. 19, 1, 17 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

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• The Cell-Penetrating Peptide Tat Facilitates Effective Internalization of PSD-95 Inhibitors Into Blood–Brain Barrier Endothelial Cells but less Efficient Permeation Across the Blood–Brain Barrier In Vitro and In Vivo

  Lisa Al Humaidan, E., Lund Pedersen, S., Burkhart, A., Laurfelt Munch Rasmussen, C., Moos, T., Fuchs, P., Alves Fernandes, E. F., Ozgür, B., Strømgaard, K., Bach, A., Larsen, B. B. & Kristensen, M., 2022, In: Frontiers in Drug Delivery - CNS Drug Delivery. 2, 17 p., 854703.

  Research output: Contribution to journal › Journal article › Research › peer-review

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• 2021

  Human induced pluripotent stem cells (BIONi010-C) generate tight cell monolayers with blood-brain barrier traits and functional expression of large neutral amino acid transporter 1 (SLC7A5)

  Goldeman, C., Andersen, M., Al-Robai, A., Buchholtz, T., Svane, N., Ozgür, B., Holst, B., Shusta, E., Hall, V. J., Saaby, L., Hyttel, P. & Brodin, B., 2021, In: European Journal of Pharmaceutical Sciences. 156, 14 p., 105577.

  Research output: Contribution to journal › Journal article › Research › peer-review
  14 Citations (Scopus)

• Screening novel CNS drug candidates for P-glycoprotein interactions using the cell line iP-gp: In vitro efflux ratios from iP-gp and MDCK-MDR1 monolayers compared to brain distribution data from mice

  Ozgür, B., Saaby, L., Janfelt, C., Langthaler, K., Eneberg, E., Jacobsen, A-M., Badolo, L., Montanari, D. & Larsen, B. B., 2021, In: European Journal of Pharmaceutics and Biopharmaceutics. 169, p. 211-219

  Research output: Contribution to journal › Journal article › Research › peer-review

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• Transendothelial electrical resistance measurement across the blood–brain barrier: A critical review of methods

  Vigh, J. P., Kincses, A., Ozgür, B., Walter, F. R., Santa-Maria, A. R., Valkai, S., Vastag, M., Neuhaus, W., Brodin, B., Dér, A. & Deli, M. A., 2021, In: Micromachines. 12, 6, 18 p., 685.

  Research output: Contribution to journal › Review › Research › peer-review

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  70 Citations (Scopus)

  31 Downloads (Pure)
• 2020

  Culture-induced changes in mRNA expression levels of efflux and SLC-transporters in brain endothelial cells

  Goldeman, C., Ozgür, B. & Brodin, B., 22 Apr 2020, In: Fluids and Barriers of the CNS. 17, 32, 12 p., 32.

  Research output: Contribution to journal › Journal article › Research › peer-review

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  10 Citations (Scopus)

  97 Downloads (Pure)
• 2018

  Characterization of the IPEC-J2 MDR1 (iP-gp) cell line as a tool for identification of P-gp substrates

  Ozgür, B., Saaby, L., Langthaler, K. & Brodin, B., 2018, In: European Journal of Pharmaceutical Sciences. 112, p. 112-121 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  8 Citations (Scopus)

• Data demonstrating the challenges of determining the kinetic parameters of P-gp mediated transport of low-water soluble substrates

  Ozgür, B., Saaby, L., Langthaler, K. & Brodin, B., 2018, In: Data in Brief. 16, p. 655-659 5 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

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  5 Citations (Scopus)

  240 Downloads (Pure)

• The iP-gp cell model is an improved tool for predicting the in vivo relevance of P-gp mediated efflux at the blood-brain barrier

  Ozgür, B., Saaby, L., Eneberg, E., Langthaler, K., Jacobsen, A-M., Janfelt, C., Badolo, L., Montanari, D. & Brodin, B., 22 Jun 2018.

  Research output: Contribution to conference › Poster › Research › peer-review
• 2017

  iP-gp , a novel cell line with tight barrier function and expression of human P-glycoprotein (ABCB1) for drug screening

  Brodin, B., Ozgür, B. & Saaby, L., 23 May 2017.

  Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

• Substrate-Dependent Inhibition of P-glycoprotein Mediated Efflux Transport of Digoxin

  Saaby, L., Ozgür, B. & Brodin, B., 14 Nov 2017, p. T7089.

  Research output: Contribution to conference › Conference abstract for conference › Research › peer-review