Research output per year
Research output per year
Research output
- 11 results
Search results
-
2024
The putative proton-coupled organic cation antiporter is involved in uptake of triptans into human brain capillary endothelial cells
Svane, N. I., Pedersen, A. B. V., Rodenberg, A., Ozgür, B., Saaby, L., Bundgaard, C., Kristensen, M., Tfelt-Hansen, P. & Larsen, B. B., 2024, In: Fluids and Barriers of the CNS. 21, 19 p., 39.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile3 Citations (Scopus)13 Downloads (Pure) -
2023
Characterization of an iPSC-based barrier model for blood-brain barrier investigations using the SBAD0201 stem cell line
Ozgür, B., Puris, E., Brachner, A., Appelt-Menzel, A., Oerter, S., Balzer, V., Holst, M. R., Christiansen, R. F., Hyldig, K., Buckley, S. T., Kristensen, M., Auriola, S., Jensen, A., Fricker, G., Nielsen, M. S., Neuhaus, W. & Brodin, B., 2023, In: Fluids and Barriers of the CNS. 20, 1, 15 p., 96.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile28 Downloads (Pure) -
Subcellular trafficking and transcytosis efficacy of different receptor types for therapeutic antibody delivery at the blood‒brain barrier
Holst, M. R., de Wit, N. M., Ozgür, B., Brachner, A., Hyldig, K., Appelt-Menzel, A., Sleven, H., Cader, Z., de Vries, H. E., Neuhaus, W., Jensen, A., Brodin, B. & Nielsen, M. S., 2023, In: Fluids and Barriers of the CNS. 20, 1, 17 p., 82.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile2 Citations (Scopus)18 Downloads (Pure) -
2022
Highly cationic cell-penetrating peptides affect the barrier integrity and facilitates mannitol permeation in a human stem cell-based blood-brain barrier model
Frøslev, P., Franzyk, H., Ozgür, B., Larsen, B. B. & Kristensen, M., 2022, In: European Journal of Pharmaceutical Sciences. 168, 10 p., 106054.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile117 Downloads (Pure) -
Hypoxia increases expression of selected blood–brain barrier transporters GLUT-1, P-gp, SLC7A5 and TFRC, while maintaining barrier integrity, in brain capillary endothelial monolayers
Ozgür, B., Helms, H. C. C., Tornabene, E. & Larsen, B. B., 2022, In: Fluids and Barriers of the CNS. 19, 1, 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile24 Downloads (Pure) -
The Cell-Penetrating Peptide Tat Facilitates Effective Internalization of PSD-95 Inhibitors Into Blood–Brain Barrier Endothelial Cells but less Efficient Permeation Across the Blood–Brain Barrier In Vitro and In Vivo
Lisa Al Humaidan, E., Lund Pedersen, S., Burkhart, A., Laurfelt Munch Rasmussen, C., Moos, T., Fuchs, P., Alves Fernandes, E. F., Ozgür, B., Strømgaard, K., Bach, A., Larsen, B. B. & Kristensen, M., 2022, In: Frontiers in Drug Delivery - CNS Drug Delivery. 2, 17 p., 854703.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile82 Downloads (Pure) -
2021
Human induced pluripotent stem cells (BIONi010-C) generate tight cell monolayers with blood-brain barrier traits and functional expression of large neutral amino acid transporter 1 (SLC7A5)
Goldeman, C., Andersen, M., Al-Robai, A., Buchholtz, T., Svane, N., Ozgür, B., Holst, B., Shusta, E., Hall, V. J., Saaby, L., Hyttel, P. & Brodin, B., 2021, In: European Journal of Pharmaceutical Sciences. 156, 14 p., 105577.Research output: Contribution to journal › Journal article › Research › peer-review
14 Citations (Scopus) -
Screening novel CNS drug candidates for P-glycoprotein interactions using the cell line iP-gp: In vitro efflux ratios from iP-gp and MDCK-MDR1 monolayers compared to brain distribution data from mice
Ozgür, B., Saaby, L., Janfelt, C., Langthaler, K., Eneberg, E., Jacobsen, A-M., Badolo, L., Montanari, D. & Larsen, B. B., 2021, In: European Journal of Pharmaceutics and Biopharmaceutics. 169, p. 211-219Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile45 Downloads (Pure) -
2020
Culture-induced changes in mRNA expression levels of efflux and SLC-transporters in brain endothelial cells
Goldeman, C., Ozgür, B. & Brodin, B., 22 Apr 2020, In: Fluids and Barriers of the CNS. 17, 32, 12 p., 32.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile10 Citations (Scopus)97 Downloads (Pure) -
2018
Characterization of the IPEC-J2 MDR1 (iP-gp) cell line as a tool for identification of P-gp substrates
Ozgür, B., Saaby, L., Langthaler, K. & Brodin, B., 2018, In: European Journal of Pharmaceutical Sciences. 112, p. 112-121 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
8 Citations (Scopus) -
Data demonstrating the challenges of determining the kinetic parameters of P-gp mediated transport of low-water soluble substrates
Ozgür, B., Saaby, L., Langthaler, K. & Brodin, B., 2018, In: Data in Brief. 16, p. 655-659 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile5 Citations (Scopus)240 Downloads (Pure)