Research output per year
Research output per year
DVM, PhD, Dipl. ECVS
Agrovej 8
2630 Taastrup
Curriculum Vitae
CASPER LINDEGAARD
PERSONAL DETAILS
Mailing Address
University of Copenhagen
Faculty of Life Sciences
Dept. Large Animal Sciences, Large Animal Surgery
Højbakkegård Allé 5, Bygning 8.68
DK-2630 Taastrup, Copenhagen
Denmark
E-mail: [email protected]
D.O.B. 07-03-1973
Nationality Danish
EDUCATION:
PhD degree within the field of Large Animal Clinical Sciences; 2009, Faculty of Life Sciences, University of Copenhagen, Denmark
Doctor of Veterinary Medicine (DVM); January 2002, Den Kongelige Veterinær og Landbohøjskole, KVL (Royal Veterinary and Agricultural University - now Faculty of Life Sciences, University of Copenhagen), Copenhagen, Denmark
PROFESSIONAL ACTIVITIES:
Post graduate employment
August 1st 2008 -
Resident of Large Animal Surgery at the Large Animal Teaching Hospital, University of Copenhagen (standard training programme within the European College of Veterinary Surgeons (ECVS))
February 1st 2007 - February 29th 2008
Scientific assistant and equine surgeon at University of Copenhagen, Faculty of Life Sciences, Department of Large Animal Sciences. This job includes clinical research, clinical teaching (equine surgery) to veterinary students and being a part of the large animal surgical team, including off-hours surgical duties. Since November 1st 2007 daily leader of anaesthesia at the Large Animal Hospital, University of Copenhagen
March 1st 2005- January 31st 2008 and March 1st - July 31st 2008
Ph.D. scholarship "Pain management in large animals" at the Department of Large Animal Sciences, Large Animal Surgery, Royal Veterinary and Agricultural University (KVL), Copenhagen, Denmark.
During the last 1 ½ year I've been working on my Ph.D.project which have the working title "Potential analgesic and anti inflammatory effects of intra-articularly administered morphine".
I'm very dedicated in the field of improving pain management in our patients. Which indeed includes better recognition of animal pain and one of the "by-products" of my Ph.D. research should be an improvement of pain scoring in equine orthopedic patients.
Within the Ph.D. scholarship I have participated in full time fulltime clinical/surgical work in the Large Animal Hospital of KVL, approximately 1 month / semester. This includes being a part of the team running the Large Animal clinic, as well as teaching undergraduate veterinary students, and giving lectures for veterinary students, and farrier trainees. The surgical work includes performing or assisting a variety of surgeries, mainly equine colic cases.
During this period I've also pursued one of my second interests; equine ophthalmology, ophthalmic surgery and ultrasonographic examination of the equine eye.
June 1st 2003 -February 28th 2005
Internship, Large Animal Hospital, Department of Large Animal Sciences, Royal Veterinary and Agricultural University, Copenhagen, Denmark.
During this period I was on a rota between day, night and weekend within the Large Animal Hospital of KVL. During day shifts I always worked within the Surgical department of the Large Animal Hospital, which included 1st opinion on referred cases, treatment of patients in the clinic, performing and assisting a wide variety of surgical procedures in mainly equine, but also bovine patients, and instructing undergraduate veterinary students. Furthermore the position included responsibility for client/owner contact and contact to the referring veterinarians. During night and weekend duty the position also included outpractice (80% equine), on non referred cases, as well as treatment of all types of patients within the Large Animal Hospital.
February 18th 2002 - May 31st 2003
Assistant veterinary surgeon. Als Dyrlæger, Alsia Dyrehospital, Keglen 2, DK-6440 Augustenborg, Denmark.
A five-vet rural mixed private practice in the southern part of Denmark. My workload consisted of 50% equine, 30% bovine and 20% small animals.
License to practice in Denmark issued February 2002
License to practice in Sweden issued July 2005
Others
August 1st 1993 - May 31st 1994
Teacher in a boarding school (8th -10th grade). My main assignment was to instruct the students in horse riding and handling, but I also functioned as a substitute in mathematics, Danish and French.
August 1st 1992 - July 31st 1993
Military service with the Royal Danish Horse Guard.
CONTINUING EDUCATION:
10th World congress of Veterinary Anesthesia, August 31st - September 4th, 2009, Glasgow, Scotland
18th Annual Scientific Meeting of the European College of Veterinary Surgeons, July 2nd - 4th, Nantes, France
Training in Equine Anaesthesia, The Phillip Leverhulme Equine Hospital, Leahurst, University of Liverpool, UK, March 23- April 3, 2009.
CPD day for the Practicing Veterinarian, The Phillip Leverhulme Equine Hospital, Leahurst, University of Liverpool, UK, March 26, 2009.
Basic Principles of Fracture Management in Horses (AO-Course), Oberdorf, Switzerland, February 11-13, 2009.
Annual meeting of the Danish Equine Veterinarian Ass., Middelfart, Denmark, October 31-November 2, 2008.
Annual symposium of the ACVS 2008, San Diego, California, USA, October 23-26, 2007 (Including "Advanced Equine Laser Surgery Lab (Kenneth Sullins)).
Annual European Equine Basic Arthroscopy Course, Muenster, Germany, May 23-24, 2008
Nordic Equine Medicine Organization, Annual Meeting 2008 - "Equine Colic", Helsinki, Finland, March 28-30
Annual symposium of the ACVS 2007, Chicago, Illinois, USA, October 17-21, 2007.
"Equine Radiology", CPD at the Royal Veterinary College, University of London, July 18-20, 2007, RVC, London, UK
"Intraocular Surgery for Advanced Surgeons." Acri.Tec., February 23-25, 2007, Berlin, Germany
9th World congress of Veterinary Anesthesia and 4th annual meeting of the International Veterinary Association of Pain Management, September 12th -16th, 2006, Santos, Brazil.
"Statistics for Veterinarians", Ph.D.-course (9 ECTS), RVAU, Copenhagen, Denmark, May-June 2006
Danish Opioid Science Centre 2006, (International conference on the use of opioids) April 27th -28th, Helsingor, Denmark, April 2006.
"Research Methodology, Planning of Controlled Clinical Trials (CCT), Basic and Laboratory research (BLR) and Epidemiological Studies (ES)", NOVA Post graduate course (6 ECTS), NOVA University, Denmark and Norway, March-April, 2006.
"Equine Anesthesia", (2 ECTS), NOVA University, Internet-based, January - February 2006.
"Laboratory Animal Science", (9 ECTS), RVAU, Copenhagen, Denmark. This course gives the opportunity to obtain a license for animal experiments in Denmark, October-November 2005.
"Surgical day", internal eduction, RVAU, 1 day, 2004.
"Ultrasonography day", internal education, RVAU, 1 day, 2005.
"Anesthesia, analgesia and euthanasia of laboratory animals", Master class course in laboratory animal science (4 ECTS), RVAU, Copenhagen, Denmark. April 2005.
Merial Animal Health Pain Management Symposium, Innsbruck, Austria, January 27th . - 30th, 2005.
Maastricht International Congress of Equine Medicine (MICEM), Maastricht, the Netherlands, December 10th-11th 2004.
"Treatment of tendonitis with stem cells", Minisymposium. Provided by Vetcell at Ansager Animal Hospital, Denmark, November 2004.
Annual meeting of the Danish Equine Veterinary Assosiation, 2003, Copenhagen, Denmark (3 days).
"Equine Wound Management & Equine Dermatology", Derek Knottenbelt in cooperation with Kruuse, Odense, Denmark (1 day), 2003.
"Equine orthopedics", modules 2, 3 and 4. Courses held by the Danish Veterinary Assosiation, Copenhagen, Denmark (total 5 days), 2002-2003.
"Equine Dentistry & Advanced equine Dentistry", Jack Easly in cooperation with Kruuse, Copenhagen, Denmark (2 days), 2003.
"Equine Herpes virus infection", Intervet, Copenhagen, Denmark (1 day), 2002.
Annual meeting of the Danish Equine Veterinary Assosiation, 2001, Helsingor, Denmark (3 days).
SCIENTIFIC ORGANISATIONS:
International Veterinary Association of Pain Management, since 2005
HONOURS:
KVL Ph.D. scholarship with tuition and salary, 2005, approximately DKK 1.5 million.
Research grants, awarded for the Ph.D. project.
"Kustos Grant", 2006, DKK 50,000.
"The Vetfond Grant", 2005, DKK 12,500.
"Intervet Denmark's grant for young veterinary scientists", 2005, DKK 9000.
OFFICES HELD:
1996-1998
Member of the competition organising committee of Kongelundens Rideklub (Local Riding club), Amager, Denmark
1994-1996
Board member Glamsbjerg Rideklub (Local Riding club), Glamsbjerg, Denmark.
1990-1996
Member of the competition organising committee of Glamsbjerg Rideklub (Local Ridingclub), Glamsbjerg, Denmark.
PROFESSIONAL PRESENTATIONS:
"Pain Evaluation in Horses", Invited oral presentation at CPD course for Equine Practitioners, arranged by Boehringer-Ingelheim Scandinavia, Copenhagen, Denmark, October 15, 2009.
„Pharmacokinetics of intra-articular morphine in a model of lipopolysaccharide-induced synovitis in horses." C Lindegaard, AB Frost, MH Thomsen, C Larsen, S Honoré-Hansen, PH Andersen. Oral presentation at the 10th World Congress of Veterinary Anaesthesia. 31st August to 4th September, 2009, Glasgow, UK.
"Comparison of a composite measure pain-scale and a visual analogue scale for orthopaedic pain in horses." C Lindegaard, MH Thomsen, S Larsen, PH Andersen. Oral presentation at the 10th World Congress of Veterinary Anaesthesia. 31st August to 4th September, 2009, Glasgow, UK.
"Analgesic efficacy of intra-articular morphine in horses with lipopolysaccharide-induced synovitis." C Lindegaard, MH Thomsen, S Larsen, PH Andersen. Oral presentation at the 10th World Congress of Veterinary Anaesthesia. 31st August to 4th September, 2009, Glasgow, UK.
"An update and how to on equine pain management", Invited oral presentation at the Annual meeting of the Danish Equine Veterinarian Ass., Middelfart, Denmark, November 2, 2008.
"Pain management in equine colic - with special emphasis on the post operative period", presentation at the Annual Meeting of the Nordic Equine Medicine Organization, Helsinki, Finland, March 28-30, 2008
"Ocular and Periorbital trauma and surgery", Lecture for Danish Equine Veterinarians, under education for Specialist approval. March 2008
"Pain and pain-modulation in horses", Lecture for Danish Equine Veterinarians, under education for Specialist approval. April 2007
"Analgesic and anti-inflammatory potentialof intra-articular morphine in an equine induced arthritis model." Presented to the faculty at Dept of Anesthesiology, Freie Universität Berlin, Berlin, Germany, March 9th, 2006.
"Analgesic and anti-inflammatory properties of locally administered opioids - with special emphasis on intra-articularly administered morphine"; oral presentation at the 2005 Abildgaard Symposium, Copenhagen, Denmark.
BIBLIOGRAPHY:
Fjeldborg, J, Lindegaard C, Ullum H. The Influence of Sedation on the Endoscopic Interpretation in the Pharynx and Larynx. Proc. of 8th Congress of the World Equine Veterinary Association 2003, p. 89
Jacobsen S, Niewold TA, Halling-Thomsen M, Nanni S, Olsen E, Lindegaard C, et al. Serum amyloid A isoforms in serum and synovial fluid in horses with lipopolysaccharide-induced arthritis. Veterinary Immunology and Immunopathology 2006;110 (3-4):325-30.
Lindegaard C., Husted L., Ullum H. and Fjeldborg J. Sedation with detomidine and acepromazine influences the endoscopic evaluation of laryngeal function in horses. Equine Veterinary Journal, 2007, 39 (6): 553-556.
A.B. Frost, S. Jacobsen, M. Halling-Thomsen, C. Lindegaard; S.W. Larsen, J. Østergaard, P.H. Andersen, C. Larsen .Intra-articular drug disappearance kinetics - Reducing the number of in vivo experiments from establishment of in vitro in vivo correlation?. Poster at SHARE (Synergy in Human Animal Research) symposium, Nov 2007, University of Copenhagen, Copenhagen, Denmark
A.B. Frost, S. Jacobsen, MH Thomsen, C. Lindegaard; S.W. Larsen, J. Østergaard, P.H. Andersen, C. Larsen .Intra-articular drug disappearance kinetics - Reducing the number of in vivo experiments from establishment of in vitro- in vivo correlation?. Poster. Annual meeting of the American Association of Pharmaceutical Scientists, November 16-20, 2008, Atlanta, GA, USA
Larsen C,C Østergaard J, Larsen S, Jensen H, Jacobsen S, Lindegaard C, Andersen Pia H. Intra-articular Depot Formulation Principles - Role in the Management of Postoperative Pain and Arthritic Disorders. J Pharm Sci, 2008, 47 (11): 4622-4654
Lindegaard C, Intra-articular morphine in horses - clinical properties in lipopolysaccharide-induced synovitis, PhD thesis, 2009, Faculty of Life Sciences, University of Copenhagen. Printed by SL grafik, Frederiksberg, Denmark; ISBN: 978-87-7611-303-2
Lindegaard C, Vaabengaard D, Christophersen M, Ekstøm C, Fjeldborg J, Evaluation of Pain and inflammation associated with hot iron branding and microchip transponder injection in horses. Am J Vet Res, 2009;70:840-847
Lindegaard C, Pihl TH, Andersen PH, Referred pain as a possible cause of poor performance in riding horses. Poster presented at the Annual conference of ECVS, Nantes, France, July 2009
S.W. Larsen, A.B. Frost, J. Østergaard1, S. Jacobsen, M.H. Thomsen, C. Lindegaard, P.H. Andersen and C. Larsen. In situ formed suspensions for local sustained action of celecoxib following intra-articular administration. Poster presented at the 36th Annual meeting and Exhibition of the Controlled Release Society, Copenhagen, Denmark, July 2009
Accepted for publication
Lindegaard C, Bech-Gleerup K, Thomsen MH, Martinussen T, Andersen PH. Anti-inflammatory effects of intra-articular morphine in experimentally induced joint inflammation in horses. Am J Vet Res, 2009.
Lindegaard, C, Thomsen, M, Larsen, S, Andersen, PH et al. Analgesic effect of intra-articularly administered morphine in a model of equine induced aseptic arthritis. Accepted for publication in Veterinary Anaesthesia and Analgesia received on 200609
Lindegaard C, Frost AB, Thomsen MH, Hansen SH, Andersen PH. Pharmacokinetics of intra-articular morphine in horses with lipopolysaccharide-induced synovitis. Accepted for publication in Veterinary Anaesthesia and Analgessia received on 221009.
Publications in work/to be submitted
Anna Buus Frost, Frank Larsen, Jesper Østergaard, Susan Weng Larsen, Casper Lindegaard, Helle Rüsz Hansen, Bente Gammelgaard, Claus Larsen. On the search for in vitro in vivo relations upon intra-articular administration of sodium diatrizoate to the horse. In review, Journal of Controlled Release
Maj Halling Thomsen1, Anders Tolver Jensen, Helle Sørensen, Casper Lindegaard, Pia
Haubro Andersen. Symmetry indices based on accelerometric data in trotting horses. In review, Journal of Biomechanics
June 2009
Defence of PhD thesis with the title: "Intra-articular morphine in horses - Clinical properties in lipopolysaccharide-induced synovitis"
August 2008 -
Residency (ECVS) in large animal surgery, University of Copenhagen, Faculty of Life Sciences, Department of Large Animal Sciences
February 2007 - February 2008
Scientific assistant and equine surgeon at University of Copenhagen, Faculty of Life Sciences, Department of Large Animal Sciences
March 2005- January 2007 and March 2008- July 2008
Ph.D. scholarship "Pain management in large animals" at the Department of Large Animal Sciences, Large Animal Surgery, Royal Veterinary and Agricultural University (KVL), Copenhagen, Denmark.June 2003 -February 2004
Internship, Large Animal Hospital, Department of Large Animal Sciences, Royal Veterinary and Agricultural University, Copenhagen, Denmark
February 2002 - May 2003Assistant veterinary surgeon. Als Dyrlæger, Alsia Dyrehospital, Keglen 2, DK-6440 Augustenborg, Denmark.
January 2002, Doctor of Veterinary Medicine (DVM), Royal Veterinary and Agricultural University, Copenhagen, DenmarkResearch output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
Research output: Contribution to journal › Journal article › Research › peer-review
Research output: Contribution to journal › Review › Research › peer-review
Research output: Contribution to journal › Journal article › Communication
Research output: Contribution to journal › Journal article › Research › peer-review
Research output: Contribution to journal › Journal article › Research › peer-review
Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
Casper Lindegaard (Speaker)
Activity: Talk or presentation types › Lecture and oral contribution
24/08/2009
1 Media contribution
Press/Media: Press / Media