Genetic analysis of blood molecular phenotypes reveals common properties in the regulatory networks affecting complex traits

Brown, A. A., Fernandez-Tajes, J. J., Hong, M. G., Brorsson, C. A., Koivula, R. W., Davtian, D., Dupuis, T., Sartori, A., Michalettou, T. D., Forgie, I. M., Adam, J., Allin, K. H., Caiazzo, R., Cederberg, H., De Masi, F., Elders, P. J. M., Giordano, G. N., Haid, M., Hansen, T. & Hansen, T. H. & 134 others, Hattersley, A. T., Heggie, A. J., Howald, C., Jones, A. G., Kokkola, T., Laakso, M., Mahajan, A., Mari, A., McDonald, T. J., McEvoy, D., Mourby, M., Musholt, P. B., Nilsson, B., Pattou, F., Penet, D., Raverdy, V., Ridderstråle, M., Romano, L., Rutters, F., Sharma, S., Teare, H., ‘t Hart, L., Tsirigos, K. D., Vangipurapu, J., Vestergaard, H., Brunak, S., Franks, P. W., Frost, G., Grallert, H., Jablonka, B., McCarthy, M. I., Pavo, I., Pedersen, O., Ruetten, H., Walker, M., Adragni, K., Allesøe, R. L. L., Artati, A. A., Arumugam, M., Atabaki-Pasdar, N., Baltauss, T., Banasik, K., Barnett, A. L., Baum, P., Bell, J. D., Beulens, J. W., Bianzano, S. B., Bizzotto, R., Bonnefond, A., Cabrelli, L., Dale, M., Dawed, A. Y., de Preville, N., Dekkers, K. F., Deshmukh, H. A., Dings, C., Donnelly, L., Dutta, A., Ehrhardt, B., Engelbrechtsen, L., Eriksen, R., Fan, Y., Ferrer, J., Fitipaldi, H., Forman, A., Fritsche, A., Froguel, P., Gassenhuber, J., Gough, S., Graefe-Mody, U., Grempler, R., Groeneveld, L., Groop, L., Gudmundsdóttir, V., Gupta, R., Hennige, A. M. H., Hill, A. V., Holl, R. W., Hudson, M., Jacobsen, U. P., Jennison, C., Johansen, J., Jonsson, A., Karaderi, T., Kaye, J., Kennedy, G., Klintenberg, M., Kuulasmaa, T., Lehr, T., Loftus, H., Lundgaard, A. T. T., Mazzoni, G., McRobert, N., McVittie, I., Nice, R., Nicolay, C., Nijpels, G., Palmer, C. N., Pedersen, H. K., Perry, M. H., Pomares-Millan, H., Prehn, C. P., Ramisch, A., Rasmussen, S., Robertson, N., Rodriquez, M., Sackett, P., Scherer, N., Shah, N., Sihinevich, I., Slieker, R. C., Sondertoft, N. B., Steckel-Hamann, B., Thomas, M. K., Thomas, C. E. E., Thomas, E. L. L., Thorand, B., Thorne, C. E., Tillner, J., Tura, A., Uhlen, M., van Leeuwen, N., van Oort, S., Verkindt, H., Vogt, J., Wad Sackett, P. W., Wesolowska-Andersen, A., Whitcher, B., White, M. W., Adamski, J., Schwenk, J. M., Pearson, E. R., Dermitzakis, E. T. & Viñuela, A., 2023, In: Nature Communications. 14, 17 p., 5062.

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Four groups of type 2 diabetes contribute to the etiological and clinical heterogeneity in newly diagnosed individuals: An IMI DIRECT study

Wesolowska-Andersen, A., Brorsson, C. A., Bizzotto, R., Mari, A., Tura, A., Koivula, R., Mahajan, A., Vinuela, A., Tajes, J. F., Sharma, S., Haid, M., Prehn, C., Artati, A., Hong, M. G., Musholt, P. B., Kurbasic, A., Masi, F. D., Tsirigos, K., Pedersen, H. K. & Gudmundsdottir, V. & 31 others, Thomas, C. E., Banasik, K., Jennison, C., Jones, A., Kennedy, G., Bell, J., Thomas, L., Frost, G., Thomsen, H., Allin, K., Hansen, T. H., Vestergaard, H., Hansen, T., Rutters, F., Elders, P., t'Hart, L., Bonnefond, A., Canouil, M., Brage, S., Kokkola, T., Heggie, A., McEvoy, D., Hattersley, A., McDonald, T., Teare, H., Ridderstrale, M., Walker, M., Forgie, I., Pedersen, O., Brunak, S. & IMI-DIRECT consortium, 2022, In: Cell Reports Medicine. 3, 1, 25 p., 100477.

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Whole blood co-expression modules associate with metabolic traits and type 2 diabetes: an IMI-DIRECT study

Gudmundsdottir, V., Pedersen, H. K., Mazzoni, G., Allin, K. H., Artati, A., Beulens, J. W., Banasik, K., Brorsson, C., Cederberg, H., Chabanova, E., De Masi, F., Elders, P. J., Forgie, I., Giordano, G. N., Grallert, H., Gupta, R., Haid, M., Hansen, T., Hansen, T. H. & Hattersley, A. T. & 36 others, Heggie, A., Hong, M.-G., Jones, A. G., Koivula, R., Kokkola, T., Laakso, M., Løngreen, P., Mahajan, A., Mari, A., McDonald, T. J., McEvoy, D., Musholt, P. B., Pavo, I., Prehn, C., Ruetten, H., Ridderstrale, M., Rutters, F., Sharma, S., Slieker, R. C., Syed, A., Tajes, J. F., Thomas, C. E., Thomsen, H. S., Vangipurapu, J., Vestergaard, H., Vinuela, A., Wesolowska-Andersen, A., Walker, M., Adamski, J., Schwenk, J. M., McCarthy, M., Pearson, E., Dermitzakis, E., Franks, P. W., Pedersen, O. & Brunak, S., 2020, In: Genome Medicine. 12, 1, 17 p., 109.

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Genetic studies of abdominal MRI data identify genes regulating hepcidin as major determinants of liver iron concentration

Wilman, H. R., Parisinos, C. A., Atabaki-Pasdar, N., Kelly, M., Thomas, E. L., Neubauer, S., Jennison, C., Ehrhardt, B., Baum, P., Schoelsch, C., Freijer, J., Grempler, R., Graefe-Mody, U., Hennige, A., Dings, C., Lehr, T., Scherer, N., Sihinecich, I., Pattou, F. & Raverdi, V. & 31 others, Caiazzo, R., Torres, F., Verkindt, H., Mari, A., Tura, A., Giorgino, T., Bizzotto, Froguel, P., Brorsson, C., Brunak, S., De Masi, F., Pedersen, H., Banasik, K., Thomas, C., Lundgaard, A., Nielsen, A., Mazzoni, G., Karaderi, T., Rasmussen, S., Johansen, J., Allesøe, R., Arumugam, M., Allin, K., Hansen, T., Hansen, T., Jonsson, A., Pedersen, O., Dutta, A., Vogt, J., Vestergaard, H. & IMI-DIRECT consortium, 2019, In: Journal of Hepatology. 71, 3, p. 594-602 9 p.

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Survival prediction in intensive-care units based on aggregation of long-term disease history and acute physiology: a retrospective study of the Danish National Patient Registry and electronic patient records

Nielsen, A. B., Thorsen-Meyer, H. C., Belling, K., Nielsen, A. P., Thomas, C. E., Chmura, P. J., Lademann, M., Moseley, P. L., Heimann, M., Dybdahl, L., Spangsege, L., Hulsen, P., Perner, A. & Brunak, S., 2019, In: The Lancet Digital Health. 1, 2, p. e78-e89 12 p.

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Network biology concepts in complex disease comorbidities

Hu, J. X., Thomas, C. E. & Brunak, S., Oct 2016, In: Nature Reviews. Genetics. 17, p. 615–629

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TumorTracer: a method to identify the tissue of origin from the somatic mutations of a tumor specimen

Marquard, A. M., Birkbak, N. J., Thomas, C. E., Favero, F., Krzystanek, M., Lefebvre, C., Ferté, C., Jamal-Hanjani, M., Wilson, G. A., Shafi, S., Swanton, C., André, F., Szallasi, Z. & Eklund, A. C., 2015, In: BMC Medical Genomics. 8, 13 p., 5.

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5S rRNA genes in Pisum: Sequence, long range and chromosomal organization

Ellis, T. H. N., Lee, D., Thomas, C. M., Simpson, P. R., Cleary, W. G., Newman, M. A. & Burcham, K. W. G., Oct 1988, In: MGG Molecular & General Genetics. 214, 2, p. 333-342 10 p.

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