Claus Cornett

Search results

• 2024

  Na⁺/H⁺-exchange inhibition by cariporide is compensated via Na⁺,HCO₃⁻-cotransport and has no net growth consequences for ErbB2-driven breast carcinomas

  Aaen, P., Kristensen, K. B., Antony, A., Hansen, S. H., Cornett, C., Pedersen, S. F. & Boedtkjer, E., 2024, In: Biochimica et Biophysica Acta - Molecular Basis of Disease. 1870, 7, 13 p., 167450.

  Research output: Contribution to journal › Journal article › Research › peer-review

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• Tailor-Made Doses of Pharmaceuticals by Tunable Modular Design: A Case Study on Tapering Antidepressant Medication

  Ahola, I., Raijada, D., Cornett, C., Bøtker, J., Rantanen, J. & Genina, N., 2024, In: Advanced Materials. 36, 30, 12 p., 2403852.

  Research output: Contribution to journal › Journal article › Research › peer-review

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  2 Citations (Scopus)

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• 2023

  A New Ellagic Acid Rhamnoside from Synadenium glaucescens and Its Cytotoxicity Evaluation

  Rwegoshora, F., Mabiki, F., Machumi, F., Chacha, M., Styrishave, B. & Cornett, C., 2023, In: Chemistry of Natural Compounds. 59, 4, p. 670-674

  Research output: Contribution to journal › Journal article › Research › peer-review

• Clinical Research Evidence Supporting Administration and Dosing Recommendations of Medicinal Cannabis as Analgesic in Cancer Patients

  Christensen, C., Allesø, M., Rose, M. & Cornett, C., 2023, In: Journal of Clinical Medicine. 12, 1, 28 p., 307.

  Research output: Contribution to journal › Review › Research › peer-review

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  3 Citations (Scopus)

  15 Downloads (Pure)

• Decoding the Postulated Entourage Effect of Medicinal Cannabis: What It Is and What It Isn’t

  Christensen, C., Rose, M., Cornett, C. & Allesø, M., 2023, In: Biomedicines. 11, 8, 25 p., 2323.

  Research output: Contribution to journal › Review › Research › peer-review

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  16 Citations (Scopus)

  9 Downloads (Pure)

• In Vitro and In Vivo Evaluation of Pellotine: A Hypnotic Lophophora Alkaloid

  Poulie, C. B. M., Chan, C. B., Parka, A., Lettorp, M., Vos, J., Raaschou, A., Pottie, E., Bundgaard, M. S., Sørensen, L. M. E., Cecchi, C. R., Märcher-Rørsted, E., Bach, A., Herth, M. M., Decker, A., Jensen, A. A., Elfving, B., Kretschmann, A. C., Stove, C. P., Kohlmeier, K. A., Cornett, C. & 3 others, Janfelt, C., Kornum, B. R. & Kristensen, J. L., 2023, In: ACS Pharmacology & Translational Science. 6, 10, p. 1492-1507

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access
  2 Citations (Scopus)

• Isolation and elucidation of antibacterial compounds from roots and stems of Synadenium glaucescens Pax

  Rwegoshora, F., Msengwa, Z., Mabiki, F., Machumi, F., Chacha, M., Styrishave, B. & Cornett, C., 2023, In: East African Journal of Science, Technology and Innovation. 4, 2, 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

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• 2022

  Activity of Sterols Isolated from the Leaves of Commiphora swynnertonii (Burtt) Against Some Nosocomial Infectious Bacteria

  Credo, D., Mabiki, F. P., Machumi, F., Chacha, M. & Cornett, C., 2022, In: The Journal of Phytopharmacology. 11, 5, p. 335-340

  Research output: Contribution to journal › Journal article › Research › peer-review

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• Anti-Newcastle Disease Virus activity of 3β and 3α Friedelanol Triterpenoids from the leaves of Synadenium glaucescens Pax

  Credo, D., Mabiki, F. P., Machumi, F., Chacha, M., Cornett, C. & Styrishave, B., 2022, In: Tropical Biomedicine. 39, 2, p. 257-264 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

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  4 Citations (Scopus)

  19 Downloads (Pure)

• Biological parameters in a declining population of narwhals (Monodon monoceros) in Scoresby Sound, Southeast Greenland

  Garde, E., Tervo, O. M., Sinding, M. H. S., Nielsen, N. H., Cornett, C. & Heide-Jørgensen, M. P., 2022, In: Arctic Science. 8, 2, p. 329-348

  Research output: Contribution to journal › Journal article › Research › peer-review

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  10 Citations (Scopus)

  32 Downloads (Pure)

• Isolation and toxicity evaluation of feruloyl ester and other triterpenoids from Synadenium glaucescens Pax

  Rwegoshora, F., Mabiki, F., Machumi, F., Chacha, M., Styrishave, B. & Cornett, C., 2022, In: The Journal of Phytopharmacology. 11, 5, p. 347-352

  Research output: Contribution to journal › Journal article › Research › peer-review

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• The concentration of lidocaine and mepivacaine measured in synovial fluid of different joints of horses after single intra-articular injection

  Adler, D. M. T., Jørgensen, E. & Cornett, C., 2022, In: Frontiers in Veterinary Science. 9, 9 p., 1007399.

  Research output: Contribution to journal › Journal article › Research › peer-review

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  2 Citations (Scopus)

  24 Downloads (Pure)
• 2021

  Data-enriched edible pharmaceuticals (Deep) with bespoke design, dose and drug release

  Chao, M., Öblom, H., Cornett, C., Bøtker, J., Rantanen, J., Sporrong, S. K. & Genina, N., 2021, In: Pharmaceutics. 13, 11, 12 p., 1866.

  Research output: Contribution to journal › Journal article › Research › peer-review

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  9 Citations (Scopus)

  31 Downloads (Pure)
• 2020

  Data-enriched edible pharmaceuticals (DEEP) of medical cannabis by inkjet printing

  Öblom, H., Cornett, C., Bøtker, J., Frokjaer, S., Hansen, H., Rades, T., Rantanen, J. & Genina, N., 2020, In: International Journal of Pharmaceutics. 589, p. 1-11 119866.

  Research output: Contribution to journal › Journal article › Research › peer-review
  39 Citations (Scopus)

• Historical chemical annotations of Cinchona bark collections are comparable to results from current day High-Pressure Liquid Chromatography technologies

  Canales, N. O. A., Gress Hansen, T. N., Cornett, C., Walker, K., Driver, F., Antonelli, A., Maldonado, C., Nesbitt, M., Barnes, C. J. & Rønsted, N., 2020, In: Journal of Ethnopharmacology. 249, 14 p., 112375.

  Research output: Contribution to journal › Journal article › Research › peer-review
  19 Citations (Scopus)

• Medication Tracking: Design and Fabrication of a Dry Powder Inhaler with Integrated Acoustic Element by 3D Printing

  Li, Y., Bohr, A., Jensen, H., Rantanen, J., Cornett, C., Beck-Broichsitter, M. & Bøtker, J. P., 2020, In: Pharmaceutical Research. 37, 3, 10 p., 38.

  Research output: Contribution to journal › Journal article › Research › peer-review
  3 Citations (Scopus)
• 2018

  Using Potentiometric Free Drug Sensors to Determine the Free Concentration of Ionizable Drugs in Colloidal Systems

  Tran, T., Chakraborty, A., Xi, X., Bohets, H., Cornett, C., Tsinman, K., Rades, T. & Müllertz, A., Jan 2018, In: Journal of Pharmaceutical Sciences. 107, 1, p. 103-112

  Research output: Contribution to journal › Journal article › Research › peer-review
  4 Citations (Scopus)
• 2017

  An optimised method for routine separation and quantification of major alkaloids in Cortex Cinchona by HPLC coupled with UV and fluorescence detection.

  Holmfred, E., Cornett, C., Maldonado, C., Rønsted, N. & Hansen, S. H., Sep 2017, In: Phytochemical Analysis. 28, 5, p. 374-380 7 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  9 Citations (Scopus)

• Phylogeny predicts the quantity of antimalarial alkaloids within the iconic yellow Cinchona bark (Rubiaceae: Cinchona calisaya)

  Maldonado Goyzueta, C. B., Barnes, C. J., Cornett, C., Holmfred, E., Hansen, S. H., Persson, C., Antonelli, A. & Rønsted, N., 2017, In: Frontiers in Plant Science. 8, 16 p., 391.

  Research output: Contribution to journal › Journal article › Research › peer-review

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  47 Citations (Scopus)

  403 Downloads (Pure)
• 2016

  In vitro release studies of insulin from lipid implants in solution and in a hydrogel matrix mimicking the subcutis

  Jensen, S. S., Jensen, H., Møller, E. H., Cornett, C., Siepmann, F., Siepmann, J. & Østergaard, J., 1 Jan 2016, In: European Journal of Pharmaceutical Sciences. 81, p. 103-12 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  33 Citations (Scopus)

• Quantification of pharmaceutical peptides in human plasma by LC-ICP-MS sulfur detection

  Møller, L. H., Macherius, A., Hansen, T. H., Nielsen, H. M., Cornett, C., Østergaard, J., Stürup, S. & Gammelgaard, B., 2016, In: Journal of Analytical Atomic Spectrometry. 31, p. 1877-1884 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

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  15 Citations (Scopus)

  629 Downloads (Pure)

• The stability and microbial contamination of bupivacaine, lidocaine and mepivacaine used for lameness diagnostics in horses

  Adler, D. M. T., Cornett, C., Damborg, P. & Verwilghen, D. R., Dec 2016, In: The Veterinary Journal. 218, p. 7-12 6 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  8 Citations (Scopus)

• Two simple cleanup methods combined with LC-MS/MS for quantification of steroid hormones in in vivo and in vitro assays

  Weisser, J. J., Hansen, C. H., Poulsen, R., Larsen, L. W., Cornett, C. & Styrishave, B., 2016, In: Analytical and Bioanalytical Chemistry. 408, 18, p. 4883-4895 13 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  46 Citations (Scopus)
• 2015

  An efficient, robust, and inexpensive grinding device for herbal samples like Cinchona bark

  Hansen, S. H., Holmfred, E., Cornett, C., Maldonado Goyzueta, C. B. & Rønsted, N., 2015, In: Scientia Pharmaceutica. 83, 2, p. 369-376 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

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  6 Citations (Scopus)

  279 Downloads (Pure)

• Evaluation of microwave oven heating for prediction of drug-excipient compatibilities and accelerated stability studies

  Schou-Pedersen, A. M. V., Østergaard, J., Cornett, C. & Hansen, S. H., 15 May 2015, In: International Journal of Pharmaceutics. 485, 1-2, p. 97-107 11 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  8 Citations (Scopus)

• Formation mechanism of coamorphous drug−amino acid mixtures

  Jensen, K. B. T., Larsen, F. H., Cornett, C., Löbmann, K., Grohganz, H. & Rades, T., 2015, In: Molecular Pharmaceutics. 12, 7, p. 2484−2492 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  75 Citations (Scopus)

• Real-time UV imaging identifies the role of pH in insulin dissolution behavior in hydrogel-based subcutaneous tissue surrogate

  Jensen, S. S., Jensen, H., Cornett, C., Møller, E. H. & Østergaard, J., 10 Mar 2015, In: European Journal of Pharmaceutical Sciences. 69, p. 26-36 11 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  22 Citations (Scopus)

• Structure elucidation and quantification of impurities formed between 6-aminocaproic acid and the excipients citric acid and sorbitol in an oral solution using high-resolution mass spectrometry and nuclear magnetic resonance spectroscopy

  Schou-Pedersen, A. M. V., Cornett, C., Nyberg, N., Østergaard, J. & Hansen, S. H., 25 Mar 2015, In: Journal of Pharmaceutical and Biomedical Analysis. 107C, p. 333-340 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  8 Citations (Scopus)
• 2014

  Insulin diffusion and self-association characterized by real-time UV imaging and Taylor dispersion analysis

  Jensen, S. S., Jensen, H., Cornett, C., Møller, E. H. & Ostergaard, J., 15 Apr 2014, In: Journal of Pharmaceutical and Biomedical Analysis. 92, p. 203-10 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  57 Citations (Scopus)

• Miniaturized approach for excipient selection during the development of oral solid dosage form

  Raijada, D. K., Müllertz, A., Cornett, C., Munk, T., Sonnergaard, J. & Rantanen, J., Mar 2014, In: Journal of Pharmaceutical Sciences. 103, 3, p. 900-8 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  8 Citations (Scopus)

• Observation of the Early Structural Changes Leading to the Formation of Protein Superstructures

  Foderà, V., Vetri, V., Wind, T. S., Noppe, W., Cornett, C., Donald, A. M., Morozova-Roche, L. A. & Vestergaard, B., 18 Sep 2014, In: Journal of Physical Chemistry Letters. 5, 18, p. 3254-3258 5 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  21 Citations (Scopus)

• Processing-induced salt formation of two oxicams in solid dosage forms affects dissolution behavior and chemical degradation

  Christensen, N. P. A., Nielsen, S., Rantanen, J., Cornett, C. & Bertelsen, P., 2014, In: Powder Technology. 266, p. 175-182

  Research output: Contribution to journal › Journal article › Research › peer-review
  4 Citations (Scopus)

• Structural basis for the transformation pathways of the sodium naproxen anhydrate-hydrate system

  Bond, A., Cornett, C., Larsen, F. H., Qu, H., Raijada, D. K. & Rantanen, J., 2014, In: IUCrJ. 1, 5, p. 328-337 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

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  25 Citations (Scopus)

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• 2013

  A high throughput platform for understanding the influence of excipients on physical and chemical stability

  Raijada, D., Cornett, C., Rantanen, J. & Raijada, D. K., 30 Aug 2013, In: International Journal of Pharmaceutics. 453, 1, p. 285-92 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  15 Citations (Scopus)

• Exploring the solid-form landscape of pharmaceutical hydrates: transformation pathways of the sodium naproxen anhydrate-hydrate system

  Raijada, D. K., Bond, A., Larsen, F. H., Cornett, C., Qu, H. & Rantanen, J., 2013, In: Pharmaceutical Research. 30, 1, p. 280-289 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

• Interpreting the disordered crystal structure of Sodium Naproxen Tetrahydrate

  Bond, A., Cornett, C., Larsen, F. H., Qu, H., Raijada, D. K. & Rantanen, J., 2013, In: Crystal Growth & Design. 13, 8, p. 3665−3671 7 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  11 Citations (Scopus)

• Rapid insight into heating-induced phase transformations in the solid state of the calcium salt of atorvastatin using multivariate data analysis

  Christensen, N. P. A., Van Eerdenbrugh, B., Kwok, K., Taylor, L. S., Bond, A., Rades, T., Rantanen, J. & Cornett, C., Mar 2013, In: Pharmaceutical Research. 30, 3, p. 826-35 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  19 Citations (Scopus)
• 2012

  Disproportionation of the calcium salt of atorvastatin in the presence of acidic excipients

  Christensen, N. P. A., Rantanen, J., Cornett, C. & Taylor, L. S., 2012, In: European Journal of Pharmaceutics and Biopharmaceutics. 82, 2, p. 410-6 7 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  34 Citations (Scopus)

• Identification of ten new designer drugs by GC-MS, UPLC-QTOF-MS, and NMR as part of a police investigation of a Danish internet company

  Reitzel, L. A., Dalsgaard, P. W., Müller, I. B. & Cornett, C., 2012, In: Drug Testing and Analysis. 4, 5, p. 342-54 13 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  39 Citations (Scopus)

• Role of excipients on solid-state properties of piroxicam during processing

  Christensen, N. P. A., Cornett, C. & Rantanen, J., 2012, In: Journal of Pharmaceutical Sciences. 101, 3, p. 1202-1211

  Research output: Contribution to journal › Journal article › Research › peer-review
  13 Citations (Scopus)
• 2011

  Assessment of crystalline disorder in cryo-milled samples of indomethacin using atomic pair-wise distribution functions

  Bøtker, J. P., Karmwar, P., Strachan, C. J., Cornett, C., Tian, F., Zujovic, Z., Rantanen, J. & Rades, T., 2011, In: International Journal of Pharmaceutics. 417, 1-2, p. 112-119 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  38 Citations (Scopus)

• Influence of temperature on solvent-mediated anhydrate-to-hydrate transformation kinetics

  Qu, H., Munk, T. P., Cornett, C., Wu, J-X., Bøtker, J. P., Christensen, L. P., Rantanen, J. T. & Tian, F., 2011, In: Pharmaceutical Research. 28, 2, p. 364-373

  Research output: Contribution to journal › Journal article › Research › peer-review
  26 Citations (Scopus)

• Insights into the early dissolution events of amlodipine using UV imaging and Raman spectroscopy

  Boetker, J. P., Savolainen, M., Koradia, V., Tian, F., Rades, T., Müllertz, A., Cornett, C., Rantanen, J. & Østergaard, J., 2011, In: Molecular Pharmaceutics. 8, 4, p. 1372-1380 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  71 Citations (Scopus)

• Physicochemical characteristics and in vitro release from oil-based vehicles of peptidomimetics: parenteral depots for intra-articular administration

  Pedersen, B. T., Østergaard, J., Larsen, S. W., Cornett, C., Ankersen, M. & Larsen, C. S., 2011, In: Drug Development and Industrial Pharmacy. 37, 1, p. 62-71

  Research output: Contribution to journal › Journal article › Research › peer-review
  5 Citations (Scopus)

• Randomized and double-blinded pilot clinical study of the safety and anti-diabetic efficacy of the Rauvolfia-Citrus tea, as used in Nigerian traditional medicine

  Campbell-Tofte, J. I. A., Mølgaard, P., Josefsen, K., Abdallah, Z., Hansen, S. H., Cornett, C., Mu, H., Richter, E. A., Petersen, H. W., Nørregaard, J. C. & Winther, K., 2011, In: Journal of Ethnopharmacology. 133, 2, p. 402-411 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  25 Citations (Scopus)
• 2010

  ¹ H NMR Spectroscopy-Based Interventional Metabolic Phenotyping: A Cohort Study of Rheumatoid Arthritis Patients

  Cornett, C., Hansen, S. H., Jaroszewski, J. W., Dorff, M. H., Nicholson, J. K., Lindon, J. C., Keun, H., Bennett, R., Danneskiold-Samsøe, B., Christensen, R., Bliddal, H. & Lauridsen, M. B., 2010, In: Journal of Proteome Research.

  Research output: Contribution to journal › Journal article › Research › peer-review

• 1H NMR spectroscopy-based interventional metabolic phenotyping: a cohort study of rheumatoid arthritis patients

  Lauridsen, M. B., Bliddal, H., Christensen, R., Danneskiold-Samsøe, B., Bennett, R., Keun, H., Lindon, J. C., Nicholson, J. K., Dorff, M. H., Jaroszewski, J. W., Hansen, S. H. & Cornett, C., 3 Sep 2010, In: Journal of Proteome Research. 9, 9, p. 4545-4553

  Research output: Contribution to journal › Journal article › Research › peer-review
  81 Citations (Scopus)

• Absorption, conjugation and excretion of the flavanones, naringenin and hesperetin from a-rhamnosidase-treated orange juice in human subjects

  Bredsdorff, L., Nielsen, I. L. F., Rasmussen, S. E., Cornett, C., Barron, D., Bouisset, F., Offord, E. & Williamson, G., 2010, In: British Journal of Nutrition. 103, 11, p. 1602-1609 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  115 Citations (Scopus)

• A role of taurine in mitochondrial function

  Hansen, S. H., Andersen, M. L., Cornett, C., Gradinaru, R. & Grunnet, N., 2010, In: Journal of Biomedical Science. 17, Suppl. 1, 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  120 Citations (Scopus)

• Pitfalls in the sample preparation and analysis of N-acylethanolamines

  Skonberg, C., Artmann, A., Cornett, C., Hansen, S. H. & Hansen, H. S., 2010, In: Journal of Lipid Research. 51, p. 3062-3073

  Research output: Contribution to journal › Journal article › Research › peer-review
  19 Citations (Scopus)