Darryl S Pickering

Research output

Research output per year 1998 2013 2016 2017 2024

• 2221 Citations
• 109 Journal article
• 4 Conference abstract in journal
• 2 Comment/debate
• 1 Book chapter
• 4 More
  • 1 Article in proceedings
  • 1 Conference abstract for conference
  • 1 Poster
  • 1 Review

Research output per year

Research output per year

Search results

• 2024

  Crystal structure of the GluK1 ligand-binding domain with kainate and the full-spanning positive allosteric modulator BPAM538

  Bay, Y., Cabello, F. J. M., Koens, C. C., Frantsen, S. M., Pickering, D. S., Frydenvang, K., Francotte, P., Pirotte, B., Kristensen, A. S., Bowie, D. & Kastrup, J. S., 2024, In: Journal of Structural Biology. 216, 3, 9 p., 108113.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  1 Downloads (Pure)

• Domoic Acid as a Lead for the Discovery of the First Selective Ligand for Kainate Receptor Subtype 5 (GluK5)

  Buschbom-Helmke, S., Wang, P., Alcaide, A., Miguez-Cabello, F., Carta, M., Viotti, J. S., Nielsen, B., Mulle, C., Bowie, D., Jørgensen, F. S., Pickering, D. S. & Bunch, L., 2024, (Accepted/In press) In: Journal of Medicinal Chemistry.

  Research output: Contribution to journal › Journal article › Research › peer-review

• Exploring thienothiadiazine dioxides as isosteric analogues of benzo- and pyridothiadiazine dioxides in the search of new AMPA and kainate receptor positive allosteric modulators

  Francotte, P., Bay, Y., Goffin, E., Colson, T., Lesenfants, C., Dorosz, J., Laulumaa, S., Fraikin, P., de Tullio, P., Beaufour, C., Botez, I., Pickering, D. S., Frydenvang, K., Danober, L., Kristensen, A. S., Kastrup, J. S. & Pirotte, B., 2024, In: European Journal of Medicinal Chemistry. 264, 15 p., 116036.

  Research output: Contribution to journal › Journal article › Research › peer-review

• Small-molecule positive allosteric modulation of homomeric kainate receptors GluK1-3: development of screening assays and insight into GluK3 structure

  Bay, Y., Venskutonytė, R., Frantsen, S. M., Thorsen, T. S., Musgaard, M., Frydenvang, K., Francotte, P., Pirotte, B., Biggin, P. C., Kristensen, A. S., Boesen, T., Pickering, D. S., Gajhede, M. & Kastrup, J. S., 2024, In: FEBS Journal. 291, 7, p. 1506-1529

  Research output: Contribution to journal › Journal article › Research › peer-review

• The positive allosteric modulator BPAM344 and L-glutamate introduce an active-like structure of the ligand-binding domain of GluK2

  Bay, Y., Egeberg Jeppesen, M., Frydenvang, K., Francotte, P., Pirotte, B., Pickering, D. S., Kristensen, A. S. & Kastrup, J. S., 2024, In: FEBS Letters. 598, 7, p. 743-757

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  1 Citation (Scopus)

  4 Downloads (Pure)

• Tritium and deuterium labelling of a kainate receptor antagonist and evaluation as a radioligand

  Chałupnik, P., Marek, A., Hovah, M. E. L., Pickering, D. S., Temperini, P., Donbosco, S., Szymańska, E. & Johansen, T. N., 2024, In: Journal of Labelled Compounds and Radiopharmaceuticals. 67, 4, p. 120-130

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  6 Downloads (Pure)
• 2023

  Structure-Activity Relationship and Solubility Studies of Novel N1-substituted Quinoxaline-2,3-diones as Kainate Receptor Antagonists

  Chałupnik, P., Vialko, A., Pickering, D. S., Nielsen, B., Bay, Y., Kristensen, A. S., Hinkkanen, M., Szczepańska, K., Karcz, T., Latacz, G., Johansen, T. N. & Szymanska, E. M., 2023, In: ChemMedChem. 18, 18, 15 p., e202300278.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  2 Citations (Scopus)

  4 Downloads (Pure)
• 2022

  (S)-2-Mercaptohistidine: A First Selective Orthosteric GluK3 Antagonist

  Poulie, C. B. M., Larsen, Y., Leteneur, C., Barthet, G., Bjorn-Yoshimoto, W. E., Malhaire, F., Nielsen, B., Pin, J. P., Mulle, C., Pickering, D. S. & Bunch, L., 2022, In: ACS Chemical Neuroscience. 13, 10, p. 1580–1587

  Research output: Contribution to journal › Journal article › Research › peer-review

• Discovery of the First Highly Selective Antagonist of the GluK3 Kainate Receptor Subtype

  Chałupnik, P., Vialko, A., Pickering, D. S., Hinkkanen, M., Donbosco, S., Møller, T. C., Jensen, A. A., Nielsen, B., Bay, Y., Kristensen, A. S., Johansen, T. N., Łątka, K., Bajda, M. & Szymańska, E., 2022, In: International Journal of Molecular Sciences. 23, 15, 16 p., 8797.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  7 Citations (Scopus)

  52 Downloads (Pure)

• Structural basis for positive allosteric modulation of AMPA and kainate receptors

  Frydenvang, K., Pickering, D. S. & Kastrup, J. S., 2022, In: The Journal of Physiology. 600, 2, p. 181-200

  Research output: Contribution to journal › Review › Research › peer-review

  Open Access

  File
  15 Citations (Scopus)

  12 Downloads (Pure)
• 2020

  A Diversity Oriented Synthesis Approach to New 2,3-trans-Substituted l-Proline Analogs as Potential Ligands for the Ionotropic Glutamate Receptors

  Kayser, S., Temperini, P., Poulie, C. B. M., Staudt, M., Nielsen, B., Pickering, D. S. & Bunch, L., 4 Mar 2020, In: ACS Chemical Neuroscience. 11, p. 702-714 13 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  7 Citations (Scopus)

• Ionotropic glutamate receptor GluA2 in complex with bicyclic pyrimidinedione-based compounds: when small compound modifications have distinct effects on binding interactions

  Frydenvang, K., Pickering, D. S., Kshirsagar, G. U., Chemi, G., Gemma, S., Sprogøe, D., Kærn, A. M., Brogi, S., Campiani, G., Butini, S. & Kastrup, J. S., 2020, In: ACS Chemical Neuroscience. 11, 12, p. 1791-1800

  Research output: Contribution to journal › Journal article › Research › peer-review
  9 Citations (Scopus)

• Stereoselective Synthesis of New (2S,3R)-3-Carboxyphenyl)pyrrolidine-2-carboxylic Acid Analogues Utilizing a C(sp3)-H Activation Strategy and Structure-Activity Relationship Studies at the Ionotropic Glutamate Receptors

  Kayser, S., Hansen, J. C., Staudt, M., Moroz, A., Larsen, Y., Temperini, P., Yi, F., Syrenne, J. T., Krogsgaard-Larsen, N., Iliadis, S., Nielsen, B., Hansen, K. B., Pickering, D. S. & Bunch, L., 2020, In: ACS Chemical Neuroscience. 11, p. 674-701 28 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access
  7 Citations (Scopus)
• 2019

  Design and Synthesis of 2,3-trans-Proline Analogs as Ligands for the Ionotropic Glutamate Receptors and the Excitatory Amino Acid Transporters

  Poulie, C. B. M., Alcaide Lopez, A., Krell-Jørgensen, M. P., Larsen, Y., Astier, E., Bjørn-Yoshimoto, W. E., Yi, F., Syrenne, J. T., Storgaard, M., Nielsen, B., Frydenvang, K. A., Jensen, A. A., Hansen, K. B., Pickering, D. S. & Bunch, L., 19 Jun 2019, In: A C S Chemical Neuroscience. 10, 6, p. 2989-3007 19 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access
  4 Citations (Scopus)

• N-(7-(1H-imidazol-1-yl)-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl)benzamide - a new kainate receptor selective antagonist and analgesic: Synthesis, X-ray crystallography, structure-affinity relationships, in vitro and in vivo pharmacology

  Møllerud, S., Hansen, R. B., Pallesen, J. S., Temperini, P., Pasini, D., Bornholdt, J., Nielsen, B., Mamedova, E., Chalupnik, P., Paternain, A. V., Lerma, J., Del Castillo, M. D., Andreasen, J. T., Frydenvang, K., Kastrup, J. S., Johansen, T. N. & Pickering, D. S., 2019, In: ACS Chemical Neuroscience. 10, p. 4685-4695 11 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  9 Citations (Scopus)

• N1-Substituted Quinoxaline-2,3-diones as Kainate Receptor Antagonists: X-ray Crystallography, Structure-Affinity Relationships and in vitro Pharmacology

  Pallesen, J. S., Møllerud, S., Frydenvang, K. A., Pickering, D. S., Bornholt, J., Nielsen, B., Pasini, D., Han, L., Marconi, L., Kastrup, J. S. J. & Johansen, T. N., 20 Mar 2019, In: A C S Chemical Neuroscience. 10, p. 1841-1853 13 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  12 Citations (Scopus)

• The Presence of Calcitonin Gene-Related Peptide and Its Receptors in Rat, Pig and Human Brain: Species Differences in Calcitonin Gene-Related Peptide Pharmacology

  Warfvinge, K., Edvinsson, L., Pickering, D. S. & Sheykhzade, M., 1 Dec 2019, In: Pharmacology. 104, p. 332-341 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  14 Citations (Scopus)

• Use of the 4-Hydroxy-Triazole Moiety as a Bioisosteric Tool for the Development of Ionotropic Glutamate Receptor Ligands

  Sainas, S., Temperini, P., Farnsworth, J. C., Yi, F., Møllerud, S., Jensen, A. A., Nielsen, B., Kastrup, J. S. J., Hansen, K. B., Boschi, D., Pickering, D. S., Clausen, R. P. & Lolli, M., 2019, In: Journal of Medicinal Chemistry. 62, p. 4467-4482

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access
  20 Citations (Scopus)
• 2018

  (S)-2-Amino-3-(5-methyl-3-hydroxyisoxazol-4-yl)propanoic Acid (AMPA) and Kainate Receptor Ligands: Further Exploration of Bioisosteric Replacements, Structural and Biological Investigation.

  Brogi, S., Brindisi, M., Butini, S., Kshirsagar, G., Maramai, S., Chemi, G., Gemma, S., Campiani, G., Novellino, E., Fiorenzani, P., Pinassi, J., Aloisi, A. M., Gynther, M., Venskutonyte, R., Han, L., Frydenvang, K. A., Kastrup, J. S. J. & Pickering, D. S., 8 Mar 2018, In: Journal of Medicinal Chemistry. 61, 5, p. 2124-2130 7 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  18 Citations (Scopus)

• Vascular and molecular pharmacology of the metabolically stable CGRP analogue, SAX

  Sheykhzade, M., Abdolalizadeh, B., Koole, C., Pickering, D. S., Dreisig, K., Johansson, S. E., Abboud, B. K., Dreier, R., Berg, J. O., Jeppesen, J. L., Sexton, P., Edvinsson, L., Wootten, D. & Sams, A., 2018, In: European Journal of Pharmacology. 829, p. 85-92

  Research output: Contribution to journal › Journal article › Research › peer-review
  9 Citations (Scopus)
• 2017

  Aryl- and heteroaryl-substituted phenylalanines as AMPA receptor ligands

  Szymańska, E., Chałupnik, P., Johansen, T. N., Nielsen, B., Cuñado Moral, A. M., Pickering, D. S. & Kieć-Kononowicz, K., 1 Dec 2017, In: Chemical Biology & Drug Design. 90, p. 1271-1281 11 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  3 Citations (Scopus)

• Augmentation of Anticancer Drug Efficacy in Murine Hepatocellular Carcinoma Cells by a Peripherally Acting Competitive N-Methyl-d-aspartate (NMDA) Receptor Antagonist

  Gynther, M., Proietti Silvestri, I., Hansen, J. C., Hansen, K. B., Malm, T., Ishchenko, Y., Larsen, Y., Han, L., Kayser, S., Auriola, S., Petsalo, A., Nielsen, B., Pickering, D. S. & Bunch, L., 14 Dec 2017, In: Journal of Medicinal Chemistry. 60, 23, p. 9885-9904 20 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  14 Citations (Scopus)

• Binding and functional pharmacological characteristics of gepant-type antagonists in rat brain and mesenteric arteries

  Sheykhzade, M., Amandi, N., Pla, M. V., Abdolalizadeh, B., Sams, A., Warfvinge, K., Edvinsson, L. & Pickering, D. S., 10 Feb 2017, In: Vascular Pharmacology. 90, p. 36-43 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  13 Citations (Scopus)

• Design and Synthesis of a Series of L-trans-4-Substituted Prolines as Selective Antagonists for the Ionotropic Glutamate Receptors Including Functional and X-ray Crystallographic Studies of New Subtype Selective Kainic Acid Receptor Subtype 1 (GluK1) Antagonist (2S,4R)-4-(2-Carboxyphenoxy)pyrrolidine-2-carboxylic Acid

  Krogsgaard-Larsen, N., Delgar, C., Koch, K., Brown, P. M. G. E., Møller, C., Han, L., Huynh, T. H. V., Hansen, S. W., Nielsen, B., Bowie, D., Pickering, D. S., Kastrup, J. S. J., Frydenvang, K. A. & Bunch, L., 2017, In: Journal of Medicinal Chemistry. 60, 1, p. 441-457 17 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  6 Citations (Scopus)

• Effects of dimeric PSD-95 inhibition on excitotoxic cell death and outcome after controlled cortical impact in rats: PSD-95 inhibition in experimental TBI

  Sommer, J. B., Bach, A., Rytter, H. M., Gynther, M., Bjerre, A-S., Gram, M. G., Marschner, L., Strømgaard, K., Mogensen, J. & Pickering, D. S., 2017, In: Neurochemical Research. 42, 12, p. 3401-3413 13 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  6 Citations (Scopus)

• Effects of the dimeric PSD-95 inhibitor UCCB01-144 on functional recovery after fimbria-fornix transection in rats

  Sommer, J. B., Bach, A., Malá, H., Strømgaard, K., Mogensen, J. & Pickering, D. S., Oct 2017, In: Pharmacology, Biochemistry and Behavior. 161, p. 62-67 6 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  2 Citations (Scopus)

• Investigation of antidepressant-like and anxiolytic-like actions and cognitive and motor side effects of four N-methyl-D-aspartate receptor antagonists in mice

  Refsgaard, L. K., Pickering, D. S. & Andreasen T., J., 1 Feb 2017, In: Behavioural Pharmacology. 28, 1, p. 37-47 11 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  19 Citations (Scopus)

• In vitro and in vivo effects of a novel dimeric inhibitor of PSD‐95 on excitotoxicity and functional recovery after experimental traumatic brain injury

  Sommer, J. B., Bach, A., Rytter, H. M., Strømgaard, K., Mogensen, J. & Pickering, D. S., 20 Jan 2017, In: European Journal of Neuroscience. 45, 2, p. 238-248 11 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  8 Citations (Scopus)

• Lessons from crystal structures of kainate receptors

  Møllerud, S., Frydenvang, K. A., Pickering, D. S. & Kastrup, J. S. J., 1 Jan 2017, In: Neuropharmacology. 112, Part A, p. 16-28 13 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  42 Citations (Scopus)

• Pharmacological characterization and binding modes of novel racemic and optically active phenylalanine-based antagonists of AMPA receptors

  Szymańska, E., Nielsen, B., Johansen, T. N., Cuñado Moral, A. M., Pickering, D. S., Szczepańska, K., Mickowska, A. & Kieć-Kononowicz, K., 2017, In: European Journal of Medicinal Chemistry. 138, p. 874-883 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  5 Citations (Scopus)

• Pharmacology and crystal structure of novel 2,3-quinoxalinediones at kainate receptors

  Møllerud, S., Pallesen, J. S., Pasini, D., Marconi, L., Han, L., Bornholt, J., Johansen, T. N., Kastrup, J. S., Pickering, D. S. & Frydenvang, K. A., Aug 2017, In: Journal of Neurochemistry. 142, S1, p. 124 1 p., MTU07-13.

  Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

• Revisiting the Quinoxalinedione scaffold in the Construction of New Ligands for the Ionotropic Glutamate Receptors.

  Demmer, C. S., Rombach, D., Liu, N., Nielsen, B., Pickering, D. S. & Bunch, L., 1 Dec 2017, In: A C S Chemical Neuroscience. 8, 11, p. 2477-2495 19 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  16 Citations (Scopus)

• Structure and affinity of two bicyclic glutamate analogues at AMPA and kainate receptors

  Møllerud, S., Pinto, A., Marconi, L., Frydenvang, K. A., Thorsen, T. S., Laulumaa, S. K., Venskutonyte, R., Winther, N., Cunado Moral, A. M., Tamborini, L., Conti, P., Pickering, D. S. & Kastrup, J. S. J., 2017, In: A C S Chemical Neuroscience. 8, 9, p. 2056-2064 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  5 Citations (Scopus)
• 2016

  A pharmacological profile of the high-affinity GluK5 kainate receptor

  Møllerud, S., Kastrup, J. S. J. & Pickering, D. S., 2016, In: European Journal of Pharmacology. 788, p. 315-320 6 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  8 Citations (Scopus)

• Design, synthesis and structure-activity relationships of novel phenylalanine-based amino acids as kainate receptors ligands

  Szymańska, E., Chałupnik, P., Szczepańska, K., Moral, A. M. C., Pickering, D. S., Nielsen, B., Johansen, T. N. & Kieć-Kononowicz, K-K., 2016, In: Bioorganic & Medicinal Chemistry Letters. 26, 22, p. 5568-5572 5 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  3 Citations (Scopus)

• Effects of sertraline, duloxetine, vortioxetine, and idazoxan in the rat affective bias test

  Refsgaard, L. K., Haubro, K., Pickering, D. S., Stuart, S., Robinson, E. & Andreasen T., J., 14 Oct 2016, In: Psychopharmacology. 233, 21, p. 3763-3770 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  7 Citations (Scopus)

• Effects of the dimeric PSD-95 inhibitor UCCB01-144 in mouse models of pain, cognition and motor function

  Andreasen, J. T., Nasser, A., Caballero-Puntiverio, M., Sahlholt, M., Bach, A., Gynther, M., Strømgaard, K. & Pickering, D. S., 5 Jun 2016, In: European Journal of Pharmacology. 780, p. 166-73 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  7 Citations (Scopus)

• Enthalpy-Entropy Compensation in the Binding of Modulators at Ionotropic Glutamate Receptor GluA2

  Krintel, C., Francotte, P., Pickering, D. S., Juknaite, L., Pøhlsgaaard, J., Olsen, L., Frydenvang, K. A., Goffin, E., Pirotte, B. & Kastrup, J. S. J., 2016, In: Biophysical Journal. 110, 11, p. 2397-2406 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  19 Citations (Scopus)

• Investigation of the presence and antinociceptive function of muscarinic acetylcholine receptors in the African naked mole-rat (Heterocephalus glaber)

  Jørgensen, K. B., Krogh-Jensen, K., Pickering, D. S., Kanui, T. & Abelson, K., 1 Jan 2016, In: Journal of Comparative Physiology A. Sensory, neural, and behavioral physiology. 202, 1, p. 7-15 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  5 Citations (Scopus)

  299 Downloads (Pure)

• Modelling Affective Pain in Mice: Effects of Inflammatory Hypersensitivity on Place Escape/Avoidance Behaviour, Anxiety and Hedonic State

  Refsgaard, L. K., Hoffmann-Petersen, J., Sahlholt, M., Pickering, D. S. & Andreasen T., J., 2016, In: Journal of Neuroscience Methods. 262, p. 85-92 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  26 Citations (Scopus)

• Neto2 influences on kainate receptor pharmacology and function

  Han, L., Howe, J. & Pickering, D. S., 2016, In: Basic & Clinical Pharmacology & Toxicology. 119, p. 141-148 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  4 Citations (Scopus)

• Positive allosteric modulation of AMPA receptors differentially modulates the behavioural effects of citalopram in mouse models of antidepressant and anxiolytic action

  Fitzpatrick, C. M., Larsen, M., Madsen, L., Pickering, D. S., Clausen, R. P. & Andreasen T., J., 26 Jun 2016, In: Behavioural Pharmacology. 27, 6, p. 549-555 7 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  9 Citations (Scopus)

• Structural rearrangement of the intracellular domains during AMPA receptor activation

  Zachariassen, L. G., Katchan, L., Jensen, A. G., Pickering, D. S., Plested, A. & Kristensen, A. S., 2016, In: Proceedings of the National Academy of Sciences USA (PNAS). 113, 27, p. E3950-E3959 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  28 Citations (Scopus)

• Structure of a High-Affinity Kainate Receptor: GluK4 Ligand-Binding Domain Crystallized with Kainate

  Kristensen, O., Kristensen, L. B., Møllerud, S., Frydenvang, K. A., Pickering, D. S. & Kastrup, J. S. J., 2016, In: Structure. 24, 9, p. 1582-1589 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  10 Citations (Scopus)

• Studies on Aryl-Substituted Phenylalanines: Synthesis, Activity, and Different Binding Modes at AMPA Receptors

  Szymanska, E., Frydenvang, K. A., Pickering, D. S., Krintel, C., Nielsen, B., Kooshki, A., Zachariassen, L. G., Olsen, L., Kastrup, J. S. J. & Johansen, T. N., 2016, In: Journal of Medicinal Chemistry. 59, 1, p. 448-461 14 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  8 Citations (Scopus)

• Synthesis and Pharmacological Characterization of the Selective GluK1 Radioligand (S)-2-Amino-3-(6-[3H]-2,4-dioxo-3,4-dihydrothieno[3,2-d]pyrimidin-1(2H)-yl)propanoic acid ([3H]-NF608)

  Alcaide, A., Marconi, L., Marek, A., Haym, I., Nielsen, B., Møllerud, S., Jensen, M., Conti, P., Pickering, D. S. & Bunch, L., 2016, In: MedChemComm. 7, p. 2136-2144 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  19 Citations (Scopus)

• Systemic and Brain Pharmacokinetics of Perforin Inhibitor Prodrugs

  Gynther, M., Pickering, D. S., Spicer, J., Denny, W. & Huttunen, K., 2016, In: Molecular Pharmaceutics. 13, 7, p. 2484-2491 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  32 Citations (Scopus)

• Tweaking subtype-selectivity and agonist efficacy at (S)-2-amino-3-(3-hydroxy-5-methyl-isoxazol-4-yl)propionic acid (AMPA) receptors in a small series of BnTetAMPA analogues

  Wang, S-Y., Larsen, Y., Navarrete, C. V., Jensen, A. A., Nielsen, B., Al-Musaed, A., Frydenvang, K., Kastrup, J. S., Pickering, D. S. & Clausen, R. P., 2016, In: Journal of Medicinal Chemistry. 59, 5, p. 2244-2254 11 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  5 Citations (Scopus)

• γ-Glutamyl-dipeptides: Easy tools to rapidly probe the stereoelectronic properties of ionotropic glutamate receptor binding pocket

  Tamborini, L., Nicosia, V., Conti, P., Dall'Oglio, F., De Micheli, C., Nielsen, B., Jensen, A. A., Pickering, D. S. & Pinto, A., 1 Dec 2016, In: Tetrahedron. 72, 51, p. 8586-8492 7 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  3 Citations (Scopus)
• 2015

  Binding Mode of an α-Amino Acid-Linked Quinoxaline-2,3-dione Analogue at Glutamate Receptor Subtype GluK1

  Demmer, C. S., Møller, C., Brown, P. M. G. E., Han, L., Pickering, D. S., Nielsen, B., Bowie, D., Frydenvang, K., Kastrup, J. S. & Bunch, L., 9 Apr 2015, In: A C S Chemical Neuroscience. 6, p. 845-854 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  17 Citations (Scopus)