Dilip Narayanan
  • Source: Scopus
20132024

Research activity per year

Personal profile

Short presentation

Biography

Dilip Narayanan started his research career at The Arctic University of Norway where he in 2017 received a PhD degree under Prof. Richard Alan Engh for the Structure based drug design efforts on ATP dependent enzymes (Protein Kinase and Heat Shock Protein 70). In 2016, he moved to copenhagen as a post doc to work with Prof. Anders Bach at University of Copenhagen to implement a FBDD platform at Department of Drug Design and Pharmacology. In 2020, he started working as Assistant Professor with Prof. Michael Gajhede on cryo-EM to apply in the field of Epigenetics. Later in 2021, he moved back to Anders Bach group to develop small-molecule ligands for the tumor necrosis factor alpha (TNF) receptors. From April 2024, he started working as Staff scientist on BioSAXS.

Research interest

Integrates research on projects understanding oxidative stress, redox signaling, inflammation and epigenetics from a societal point of view. 

Expertise areas

  • Techniques:  Structural biology (X-ray and cryo-EM), protein chemistry, fragment-based drug discovery (FBDD), bioassays (TSA, SPR and FP) for ligand-protein interactions, Structure-based drug design (X-ray, molecular modelling).
  • Targets: Protein-protein interactions (PPIs), oxidative stress (Keap1), Redox signaling (NADPH oxidase 2), inflammation (TNF receptors) and epigenetics (KDM5B).

Bibliometrics

See Scopus and Google scholar.

CV

Education
2017: Ph.D. in Molecular and Structural Biology, UiT The Arctic University of Norway
2006: M.Sc. in Bioinformatics, University of Madras
2003: B.Sc. in Chemistry, University of Calicut

Positions

2024-: Facility Manager at CPHSAXS, Department of Drug Design and Pharmacology (DDP) at the University of Copenhagen (UCPH)
2021-2024: Assistant Professor in Medicinal Chemistry Research (MCR), Department of Drug Design and Pharmacology (DDP) at the University of Copenhagen (UCPH)
2020- 2021: Assistant Professor in Peptides and Proteins, DDP, UCPH
2016-2020: Postdoc, MCR, DDP, UCPH
2008-2010: Application Scientist, Systems Biology Worldwide, Finland
2006-2008: Scientific Analyst, Insilico Consulting, India

Research management – experience, courses
2010-: Supervised (incl. current) 1 PhD, and 12 master/bachelor’s students
2021: University pedagogy course, UCPH

Teaching
2019-2024: Courses in Molecular Pharmacology, Medicinal and Biostructural Chemistry, Pharmaceutical Biology at UCPH and Preclinical drug development at DTU. 

Keywords

  • Faculty of Health and Medical Sciences
  • Structural Biology
  • X-ray
  • Cryo-EM
  • XCHEM Screening
  • Molecular modeling
  • Fragment-based drug discovery
  • Assay development and screening
  • Surface Plasmon Resonance (SPR)
  • Fluorescence polarization (FP)
  • Thermal shift assay (TSA)
  • Protein-protein interactions
  • CNS drug discovery
  • CNS diseases
  • Ischemic Stroke
  • Keap1
  • NADPH oxidase
  • TNFR
  • BioSAXS

Collaborations and top research areas from the last five years

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