Research output per year
Research output per year
Personal profile
Short presentation
Fena Ochs received her Ph.D. in 2018 from the Novo Nordisk Foundation Centre for Protein Research at the University of Copenhagen. Her doctoral dissertation under supervision of Prof Jiri Lukas described a novel role for the tumour suppressor 53BP1 in control of homology-directed repair and identified a tight interconnection between 3D chromatin organization and the DNA damage response. Dr. Ochs joined the laboratory of Prof Kim Nasmyth at the University of Oxford in 2019, where her research illuminated the role of cohesin complexes in 3D chromatin organization. Fena’s background is in cutting-edge microscopy technologies, including high-content and live-3D-Structured Illumination super-resolution microscopy. In 2023, Fena was appointed Associate Professor and Group Leader at the Faculty of Health and Medical Sciences at the University of Copenhagen.
Possible conflicts of interest
Paid consultant to Imsol
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
-
Organization of replicated chromosomes by DNA loops and sister chromatid cohesion
Ochs, F. & Gerlich, D. W., 2026, In: Nature Reviews Molecular Cell Biology. 27, p. 344–357Research output: Contribution to journal › Review › peer-review
3 Citations (Scopus) -
Putting numbers on chromatin looping
Henggeler, A. & Ochs, F., 2026, (E-pub ahead of print) In: Nature Structural & Molecular Biology. 2 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
-
DDIAS is a single-stranded DNA-binding effector of the TOPBP1-CIP2A complex in mitosis
Tsukada, K., Lototska, L., Tsukada, A., Gönenç, I. I., Sherlaw Sturrock, C., Kanade, M., Oliver, A. W., Jones, S. E., Jhujh, S. S., Bannister, J., Pouzet, A., Levy , J., Ali, A., Raza, M. A. S., Toft, M., Iqbal, Z., Fatima, A., Miller, T., Stewart, G. S. & Ochs, F. & 1 others, , 10 Sept 2025, bioRxiv, 50 p.Research output: Working paper › Preprint
File8 Downloads (Pure) -
Sister chromatid cohesion is mediated by individual cohesin complexes
Ochs, F., Green, C., Szczurek, A. T., Pytowski, L., Kolesnikova, S., Brown, J., Gerlich, D. W., Buckle, V., Schermelleh, L. & Nasmyth, K. A., 2024, In: Science. 383, 6687, p. 1122-1130 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
29 Citations (Scopus) -
Mitotic DNA synthesis is caused by transcription-replication conflicts in BRCA2-deficient cells
Groelly, F. J., Dagg, R. A., Petropoulos, M., Rossetti, G. G., Prasad, B., Panagopoulos, A., Paulsen, T., Karamichali, A., Jones, S. E., Ochs, F., Dionellis, V. S., Puig Lombardi, E., Miossec, M. J., Lockstone, H., Legube, G., Blackford, A. N., Altmeyer, M., Halazonetis, T. D. & Tarsounas, M., 2022, In: Molecular Cell. 82, 18, p. 3382-3397.e7 24 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open Access46 Citations (Scopus) -
Replication Labeling Methods for Super-Resolution Imaging of Chromosome Territories and Chromatin Domains
Miron, E., Windo, J., Ochs, F. & Schermelleh, L., 2022, Chromosome Architecture. Leake, M. C. (ed.). 2 ed. Springer, p. 111-128 18 p. (Methods in Molecular Biology, Vol. 2476).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
-
Physiological Tolerance to ssDNA Enables Strand Uncoupling during DNA Replication
Ercilla, A., Benada, J., Amitash, S., Zonderland, G., Baldi, G., Somyajit, K., Ochs, F., Costanzo, V., Lukas, J. & Toledo, L., 2020, In: Cell Reports. 30, 7, p. 2416-2429.e7 22 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile61 Citations (Scopus)273 Downloads (Pure) -
Stabilization of chromatin topology safeguards genome integrity
Ochs, F., Karemore, G., Miron, E., Brown, J., Sedlackova, H., Rask, M.-B., Lampe, M., Buckle, V., Schermelleh, L., Lukas, J. & Lukas, C., 2019, In: Nature. 574, 7779, p. 571-574 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile166 Citations (Scopus)204 Downloads (Pure)
Prizes
-
Eppendorf Award 2025 Finalist
Ochs, F. (Recipient), 3 Jul 2025
Prize: Prizes, scholarships, distinctions