Research output per year
Research output per year
Personal profile
Short presentation
Targeted medicinal chemistry towards antibiotics and anti-cancer compounds and Focus on compounds with aim to overcome drug-resistance
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Research output
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Polymyxins with Potent Antibacterial Activity against Colistin-Resistant Pathogens: Fine-Tuning Hydrophobicity with Unnatural Amino Acids
Jørgensen, J. S., Mood, E. H., Knap, A. S. H., Nielsen, S. E., Nielsen, P. E., Żabicka, D., Matias, C., Domraceva, I., Björkling, F. & Franzyk, H., 2024, In: Journal of Medicinal Chemistry. 67, 2, p. 1370–1383Research output: Contribution to journal › Journal article › Research › peer-review
1 Citation (Scopus) -
Studies of antibacterial activity (in vitro and in vivo) and mode of action for des-acyl tridecaptins (DATs)
Couturier, C., Ronzon, Q., Lattanzi, G., Lingard, I., Coyne, S., Cazals, V., Dubarry, N., Yvon, S., Leroi-Geissler, C., Gracia, O. R., Teague, J., Sordello, S., Corbett, D., Bauch, C., Monlong, C., Payne, L., Taillier, T., Fuchs, H., Broenstrup, M., Harrison, P. H. & 10 others, , 2024, In: European Journal of Medicinal Chemistry. 265, 20 p., 116097.Research output: Contribution to journal › Journal article › Research › peer-review
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Antimicrobial Peptides Incorporating Halogenated Marine-Derived Amino Acid Substituents
Craig, A. J., Ermolovich, Y., Cameron, A., Rodler, A., Wang, H., Hawkes, J. A., Hubert, M., Bjoerkling, F., Molchanova, N., Brimble, M. A., Moodie, L. W. K. & Svenson, J., 2023, In: ACS Medicinal Chemistry Letters. 14, 6, p. 802–809 8 p.Research output: Contribution to journal › Letter › Research › peer-review
Open Access2 Citations (Scopus) -
Exploring the Potential of Sulfur Moieties in Compounds Inhibiting Steroidogenesis
Wróbel, T. M., Sharma, K., Mannella, I., Oliaro-Bosso, S., Nieckarz, P., Du Toit, T., Voegel, C. D., Rojas Velazquez, M. N., Yakubu, J., Matveeva, A., Therkelsen, S., Jørgensen, F. S., Pandey, A. V., Pippione, A. C., Lolli, M. L., Boschi, D. & Björkling, F., 2023, In: Biomolecules. 13, 9, 18 p., 1349.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile1 Citation (Scopus)11 Downloads (Pure) -
Non-steroidal CYP17A1 Inhibitors: Discovery and Assessment
Wróbel, T. M., Jørgensen, F. S., Pandey, A. V., Grudzińska, A., Sharma, K., Yakubu, J. & Björkling, F., 2023, In: Journal of Medicinal Chemistry. 66, 10, p. 6542–6566Research output: Contribution to journal › Review › Research › peer-review
Open AccessFile14 Citations (Scopus)15 Downloads (Pure) -
Selected strategies to fight pathogenic bacteria
Plotniece, A., Sobolev, A., Supuran, C. T., Carta, F., Björkling, F., Franzyk, H., Yli-Kauhaluoma, J., Augustyns, K., Cos, P., De Vooght, L., Govaerts, M., Aizawa, J., Tammela, P. & Žalubovskis, R., 2023, In: Journal of Enzyme Inhibition and Medicinal Chemistry. 38, 1, 27 p., 2155816.Research output: Contribution to journal › Review › Research › peer-review
Open AccessFile29 Citations (Scopus)13 Downloads (Pure) -
Structure-activity study of oncocin: On-resin guanidinylation and incorporation of homoarginine, 4-hydroxyproline or 4,4-difluoroproline residues
Shaikh, A. Y., Björkling, F., Zabicka, D., Tomczak, M., Urbas, M., Domraceva, I., Kreicberga, A. & Franzyk, H., 2023, In: Bioorganic Chemistry. 141, 11 p., 106876.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile3 Citations (Scopus)10 Downloads (Pure) -
Imitation of β-lactam binding enables broad-spectrum metallo-β-lactamase inhibitors
Brem, J., Panduwawala, T., Hansen, J. U., Hewitt, J., Liepins, E., Donets, P., Espina, L., Farley, A. J. M., Shubin, K., Campillos, G. G., Kiuru, P., Shishodia, S., Krahn, D., Leśniak, R. K., Schmidt (Adrian), J., Calvopiña, K., Turrientes, M. C., Kavanagh, M. E., Lubriks, D., Hinchliffe, P. & 41 others, , 2022, In: Nature Chemistry. 14, p. 15–24Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile44 Citations (Scopus)9 Downloads (Pure)