Research output per year
Research output per year
Personal profile
Teaching
currently responsable for the Master course 'Epigenetics and Cell Differentiation'
Short presentation
My laboratory studies heterochromatin formation and genome dynamics in the fission yeast Schizosaccharomyces pombe. Specific aspects on which we have focused in recent years are sumoylation, chromatin boundary formation, and theoretical modeling of heterochromatin formation. Locally, we collaborate with Physicists at NBI (Kim Sneppen, Ala Trusina, Lene Oddershede) and with the group of Karen Skriver in the Department of BIology. Our current international collaborators include Thomas Schalch (University of Geneva), Ron Hay (University of Dundee), and Hisao Masai (Tokyo Metropolitant Institute of Medical Science).
Education/Academic qualification
Postdoc, National Cancer Institute
1990 → 1994
PhD student, Fred Hutchinson Cancer Research Center
1986 → 1990
Master Student, Institut Pasteur
1985 → 1986
Undergraduate, École Normale Supérieure
1982 → 1986
PhD Life and Health Sciences, Sorbonne Université
1990 → …
Keywords
- Faculty of Science
- Epigenetics
- Chromatin structure and function
- Fission yeast
- RNA interference
- Nuclear Organization
- Recombination
- sumoylation
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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The fork protection complex promotes parental histone recycling and epigenetic memory
Charlton, S. J., Flury, V., Kanoh, Y., Genzor, A. V., Kollenstart, L., Ao, W., Brøgger, P., Weisser, M. B., Adamus, M., Alcaraz, N., Delvaux de Fenffe, C. M., Mattiroli, F., Montoya, G., Masai, H., Groth, A. & Thon, G., 2024, In: Cell. 187, 18, p. 5029-5047.e21 41 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile9 Citations (Scopus)3 Downloads (Pure) -
Fission yeast Swi2 designates cell-type specific donor and stimulates Rad51-driven strand exchange for mating-type switching
Maki, T., Thon, G. & Iwasaki, H., 2023, In: Nucleic acids symposium series. 51, 8, 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile21 Downloads (Pure) -
Euchromatin factors HULC and Set1C affect heterochromatin organization and mating-type switching in fission yeast Schizosaccharomyces pombe
Esquivel-Chávez, A., Maki, T., Tsubouchi, H., Handa, T., Kimura, H., Haber, J. E., Thon, G. & Iwasaki, H., 2022, In: Genes and Genetic Systems. 97, 3, p. 123-138 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile4 Citations (Scopus)19 Downloads (Pure) -
The transcription factor Atf1 lowers the transition barrier for nucleosome-mediated establishment of heterochromatin
Nickels, J. F., Della-Rosa, M. E., Miguelez Goyeneche, I., Charlton, S. J., Sneppen, K. & Thon, G., 2022, In: Cell Reports. 39, 7, 17 p., 110828.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile10 Citations (Scopus)48 Downloads (Pure) -
Establishment of heterochromatin in domain-size-dependent bursts
Nickels, J. F., Edwards, A. K., Charlton, S. J., Mortensen, A. M., Hougaard, S. C. L., Trusina, A., Sneppen, K. & Thon, G., 13 Apr 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 15, 11 p., e2022887118.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile16 Citations (Scopus)93 Downloads (Pure) -
Integrity of a heterochromatic domain ensured by its boundary elements
Charlton, S. J., Jørgensen, M. M. & Thon, G., 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 35, p. 21504-21511 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile11 Citations (Scopus)45 Downloads (Pure) -
Mating-type switching by homology-directed recombinational repair: a matter of choice
Thon, G., Maki, T., Haber, J. E. & Iwasaki, H., 2019, In: Current Genetics. 65, 2, p. 351-362Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile23 Citations (Scopus)132 Downloads (Pure) -
Dependency of Heterochromatin Domains on Replication Factors
Jahn, L. J., Mason, B., Brøgger, P., Toteva, T., Nielsen, D. K. & Thon, G., 2018, In: G3: Genes, Genomes, Genetics (Bethesda). 8, 2, p. 477-489 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile21 Citations (Scopus)203 Downloads (Pure)
Activities
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8th International Fission Yeast meeting
Genevieve Thon (Speaker)
23 Jun 2015Activity: Participating in an event - types › Organisation of and participation in conference
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Pombe Club, London Research Institute
Genevieve Thon (Speaker)
15 Jul 2014Activity: Participating in an event - types › Organisation of and participation in conference
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EMBO course Molecular genetics with fission yeast
Genevieve Thon (Speaker)
29 Jun 2014 → 11 Jul 2014Activity: Participating in an event - types › Participation in workshop, seminar, course
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TriRhena Meeting
Genevieve Thon (Speaker)
23 Jun 2014Activity: Participating in an event - types › Organisation of and participation in conference
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Lamarck, Landmarks and Landscapes: frontiers in epigenetics
Genevieve Thon (Speaker)
18 Feb 2014Activity: Participating in an event - types › Organisation of and participation in conference
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Heterochromatin Establishment, Dynamics of Stem Cell Decisions
Genevieve Thon (Speaker)
28 Aug 2013Activity: Participating in an event - types › Organisation of and participation in conference
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7th International Fission Yeast meeting
Genevieve Thon (Speaker)
25 Aug 2013Activity: Participating in an event - types › Organisation of and participation in conference
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EMBO course Molecular genetics with fission yeast
Genevieve Thon (Speaker)
3 Jul 2012 → 12 Jul 2012Activity: Participating in an event - types › Participation in workshop, seminar, course