Hans Bräuner

Research output

Research output per year 1993 2002 2003 2004 2005 2007 2008 2009 2010 2012 2013 2014 2015 2017 2019 2020 2024

• 10433 Citations
• 229 Journal article
• 11 Book chapter
• 6 Review
• 4 Conference abstract in journal
• 4 More
  • 1 Conference abstract for conference
  • 1 Comment/debate
  • 1 Editorial
  • 1 Letter

Research output per year

Research output per year

Search results

• 2024

  Characterization of the real-time internalization of nine GPCRs reveals distinct dependence on arrestins and G proteins

  Møller, T. C., Moo, E. V., Inoue, A., Pedersen, M. F. & Bräuner-Osborne, H., 2024, In: Biochimica et Biophysica Acta - Molecular Cell Research. 1871, 1, 12 p., 119584.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

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  1 Citation (Scopus)

  18 Downloads (Pure)

• Differential G protein activation by the long and short isoforms of the dopamine D₂ receptor

  Reiner-Link, D., Madsen, J. S., Gloriam, D. E., Bräuner-Osborne, H. & Hauser, A. S., 2024, (Accepted/In press) In: British Journal of Pharmacology.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access
  3 Citations (Scopus)

• Fish-hunting cone snail disrupts prey’s glucose homeostasis with weaponized mimetics of somatostatin and insulin

  Yeung, H. Y., Ramiro, I. B. L., Andersen, D. B., Koch, T. L., Hamilton, A., Bjørn-Yoshimoto, W. E., Espino, S., Vakhrushev, S. Y., Pedersen, K. B., de Haan, N., Hipgrave Ederveen, A. L., Olivera, B. M., Knudsen, J. G., Bräuner-Osborne, H., Schjoldager, K. T., Holst, J. J. & Safavi-Hemami, H., 2024, In: Nature Communications. 15, 1, 16 p., 6408.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

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  3 Downloads (Pure)

• Loss-of-Function Thr347Ala Variant in the G Protein Subunit-α11 Causes Familial Hypocalciuric Hypercalcemia 2 (FHH2)

  Boisen, I. M., Du, W., Juul, A., Bräuner-Osborne, H., Jensen, A. A. & Blomberg Jensen, M., 2024, (E-pub ahead of print) In: The Journal of clinical endocrinology and metabolism.

  Research output: Contribution to journal › Journal article › Research › peer-review

• Structure-Activity Relationship Studies and Optimization of 4-Hydroxypyridones as GPR84 Agonists

  Ieremias, L., Kaspersen, M. H., Manandhar, A., Schultz-Knudsen, K., Vrettou, C. I., Pokhrel, R., Heidtmann, C. V., Jenkins, L., Kanellou, C., Marsango, S., Li, Y., Bräuner-Osborne, H., Rexen Ulven, E., Milligan, G. & Ulven, T., 2024, In: Journal of Medicinal Chemistry. 67, 5, p. 3542-3570

  Research output: Contribution to journal › Journal article › Research › peer-review
• 2023

  Endocytic proteins mediating GPR15 receptor internalization provide insight into the underlying mechanisms

  Deng, Y., Von Moo, E., Inoue, A. & Braeuner-Osborne, H., 2023, In: FEBS Letters. 597, 11, p. 1528-1540

  Research output: Contribution to journal › Journal article › Research › peer-review

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  22 Downloads (Pure)

• Pharmacological characterization of novel small molecule agonists and antagonists for the orphan receptor GPR139

  Pallareti, L., Rath, T. F., Trapkov, B., Tsonkov, T., Nielsen, A. T., Harpsøe, K., Gentry, P. R., Bräuner-Osborne, H., Gloriam, D. E. & Foster, S. R., 2023, In: European Journal of Pharmacology. 943, 175553.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

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  3 Citations (Scopus)

  29 Downloads (Pure)

• Structure–activity relationship of GPR15L peptide analogues and investigation of their interaction with the GPR15 receptor

  Deng, Y., Perez Almeria, C. V., van Gijzel, L., Schaller, K., Vedel, L., Gloriam, D. E., Ulven, T. & Bräuner-Osborne, H., 2023, In: Basic and Clinical Pharmacology and Toxicology. 132, 6, p. 459-471

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  4 Citations (Scopus)

  21 Downloads (Pure)

• The Concise Guide to PHARMACOLOGY 2023/24: G protein-coupled receptors

  Alexander, S. P. H., Christopoulos, A., Davenport, A. P., Kelly, E., Mathie, A. A., Peters, J. A., Veale, E. L., Armstrong, J. F., Faccenda, E., Harding, S. D., Davies, J. A., Abbracchio, M. P., Abraham, G., Agoulnik, A., Alexander, W., Al-Hosaini, K., Bäck, M., Baker, J. G., Barnes, N. M., Bathgate, R. & 146 others, Beaulieu, J-M., Beck-Sickinger, A. G., Behrens, M., Bernstein, K. E., Bettler, B., Birdsall, N. J. M., Blaho, V., Boulay, F., Bousquet, C., Bräuner-Osborne, H., Burnstock, G., Caló, G., Castaño, J. P., Catt, K. J., Ceruti, S., Chazot, P., Chiang, N., Chini, B., Chun, J., Cianciulli, A., Civelli, O., Clapp, L. H., Couture, R., Cox, H. M., Csaba, Z., Dahlgren, C., Dent, G., Douglas, S. D., Dournaud, P., Eguchi, S., Escher, E., Filardo, E. J., Fong, T., Fumagalli, M., Gainetdinov, R. R., Garelja, M. L., de Gasparo, M., Gerard, C., Gershengorn, M., Gobeil, F., Goodfriend, T. L., Goudet, C., Grätz, L., Gregory, K. J., Gundlach, A. L., Hamann, J., Hanson, J., Hauger, R. L., Hay, D. L., Heinemann, A., Herr, D., Hollenberg, M. D., Holliday, N. D., Horiuchi, M., Hoyer, D., Hunyady, L., Husain, A., IJzerman, A. P., Inagami, T., Jacobson, K. A., Jensen, R. T., Jockers, R., Jonnalagadda, D., Karnik, S., Kaupmann, K., Kemp, J., Kennedy, C., Kihara, Y., Kitazawa, T., Kozielewicz, P., Kreienkamp, H-J., Kukkonen, J. P., Langenhan, T., Larhammar, D., Leach, K., Lecca, D., Lee, J. D., Leeman, S. E., Leprince, J., Li, X. X., Lolait, S. J., Lupp, A., Macrae, R., Maguire, J., Malfacini, D., Mazella, J., McArdle, C. A., Melmed, S., Michel, M. C., Miller, L. J., Mitolo, V., Mouillac, B., Müller, C. E., Murphy, P. M., Nahon, J-L., Ngo, T., Norel, X., Nyimanu, D., O'Carroll, A-M., Offermanns, S., Panaro, M. A., Parmentier, M., Pertwee, R. G., Pin, J-P., Prossnitz, E. R., Quinn, M., Ramachandran, R., Ray, M., Reinscheid, R. K., Rondard, P., Rovati, G. E., Ruzza, C., Sanger, G. J., Schöneberg, T., Schulte, G., Schulz, S., Segaloff, D. L., Serhan, C. N., Singh, K. D., Smith, C. M., Stoddart, L. A., Sugimoto, Y., Summers, R., Tan, V. P., Thal, D., Thomas, W. W., Timmermans, P. B. M. W. M., Tirupula, K., Toll, L., Tulipano, G., Unal, H., Unger, T., Valant, C., Vanderheyden, P., Vaudry, D., Vaudry, H., Vilardaga, J-P., Walker, C. S., Wang, J. M., Ward, D. T., Wester, H-J., Willars, G. B., Williams, T. L., Woodruff, T. M., Yao, C. & Ye, R. D., Oct 2023, In: British Journal of Pharmacology. 180 Suppl 2, p. S23-S144

  Research output: Contribution to journal › Journal article › Research › peer-review
  116 Citations (Scopus)
• 2022

  Delineation of the GPR15 receptor-mediated Gα protein signalling profile in recombinant mammalian cells

  Deng, Y., Moo, E. V., Almería, C. V. P., Gentry, P. R., Vedel, L., Mathiesen, J. M. & Bräuner-Osborne, H., 2022, In: Basic and Clinical Pharmacology and Toxicology. 131, 2, p. 104-113

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

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  6 Citations (Scopus)

  32 Downloads (Pure)

• Development of a medium throughput whole-cell microtiter plate Thr286 autophosphorylation assay for CaMKIIα using ELISA

  Palmelund, L. B., van Woerden, G. M., Bräuner-Osborne, H. & Wellendorph, P., 2022, In: Journal of Pharmacological and Toxicological Methods. 118, 8 p., 107226.

  Research output: Contribution to journal › Journal article › Research › peer-review

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  19 Downloads (Pure)

• Ligand-directed bias of G protein signaling at the dopamine D₂ receptor

  Von Moo, E., Harpsøe, K., Hauser, A. S., Masuho, I., Bräuner-Osborne, H., Gloriam, D. E. & Martemyanov, K. A., 2022, In: Cell Chemical Biology. 29, 2, p. 226-238

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access
  20 Citations (Scopus)

• Molecular insights into ligand recognition and G protein coupling of the neuromodulatory orphan receptor GPR139

  Zhou, Y., Daver, H., Trapkov, B., Wu, L., Wu, M., Harpsøe, K., Gentry, P. R., Liu, K., Larionova, M., Liu, J., Chen, N., Bräuner-Osborne, H., Gloriam, D. E., Hua, T. & Liu, Z. J., 2022, In: Cell Research. 32, 2, p. 210-213

  Research output: Contribution to journal › Letter › Research › peer-review

  Open Access

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  15 Citations (Scopus)

  41 Downloads (Pure)

• Somatostatin venom analogs evolved by fish-hunting cone snails: From prey capture behavior to identifying drug leads

  Ramiro, I. B. L., Bjørn-Yoshimoto, W. E., Imperial, J. S., Gajewiak, J., Salcedo, P. F., Watkins, M., Taylor, D., Resager, W., Ueberheide, B., Bräuner-Osborne, H., Whitby, F. G., Hill, C. P., Martin, L. F., Patwardhan, A., Concepcion, G. P., Olivera, B. M. & Safavi-Hemami, H., 2022, In: Science Advances. 8, 12, 16 p., eabk1410.

  Research output: Contribution to journal › Journal article › Research › peer-review

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  18 Citations (Scopus)

  38 Downloads (Pure)

• Use of CRISPR/Cas9-edited HEK293 cells reveals that both conventional and novel protein kinase C isozymes are involved in mGlu_5a receptor internalization

  van Senten, J. R., Møller, T. C., Moo, E. V., Seiersen, S. D. & Bräuner-Osborne, H., 2022, In: Journal of Biological Chemistry. 298, 10, 16 p., 102466.

  Research output: Contribution to journal › Journal article › Research › peer-review

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  4 Citations (Scopus)

  16 Downloads (Pure)
• 2021

  Arrestin-Dependent and -Independent Internalization of G Protein–Coupled Receptors: Methods, Mechanisms, and Implications on Cell Signaling

  Moo, E. V., Van Senten, J. R., Bräuner-osborne, H. & Møller, T. C., 2021, In: Molecular Pharmacology. 99, 4, p. 242-255

  Research output: Contribution to journal › Journal article › Research › peer-review

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  43 Citations (Scopus)

  46 Downloads (Pure)

• Asymmetric activation of the calcium-sensing receptor homodimer

  Gao, Y., Robertson, M. J., Rahman, S. N., Seven, A. B., Zhang, C., Meyerowitz, J. G., Panova, O., Hannan, F. M., Thakker, R. V., Bräuner-Osborne, H., Mathiesen, J. M. & Skiniotis, G., 2021, In: Nature. 595, p. 455-459

  Research output: Contribution to journal › Journal article › Research › peer-review

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  70 Citations (Scopus)

  19 Downloads (Pure)

• GLP-1 Val8: A Biased GLP-1R Agonist with Altered Binding Kinetics and Impaired Release of Pancreatic Hormones in Rats

  van der Velden, W. J. C., Smit, F. X., Christiansen, C. B., Møller, T. C., Hjortø, G. M., Larsen, O., Schiellerup, S. P., Bräuner-Osborne, H., Holst, J. J., Hartmann, B., Frimurer, T. M. & Rosenkilde, M. M., 2021, In: ACS Pharmacology & Translational Science. 4, 1, p. 296-313 18 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access
  28 Citations (Scopus)

• Mutational Landscape of the Proglucagon-Derived Peptides

  Lindquist, P., Madsen, J. S., Brauner-Osborne, H., Rosenkilde, M. M. & Hauser, A. S., 2021, In: Frontiers in Endocrinology. 12, 14 p., 698511.

  Research output: Contribution to journal › Journal article › Research › peer-review

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  9 Citations (Scopus)

  28 Downloads (Pure)

• Positive allosteric modulators of metabotropic glutamate receptor 5 as tool compounds to study signaling bias

  Arsova, A., Møller, T. C., Hellyer, S. D., Vedel, L., Foster, S. R., Hansen, J. L., Bräuner-osborne, H. & Gregory, K. J., 1 May 2021, In: Molecular Pharmacology. 99, 5, p. 328-241

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

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  5 Citations (Scopus)

  27 Downloads (Pure)

• The Calcium-Sensing Receptor Is Essential for Calcium and Bicarbonate Sensitivity in Human Spermatozoa

  Boisen, I. M., Rehfeld, A., Mos, I., Poulsen, N. N., Nielsen, J. E., Schwarz, P., Rejnmark, L., Dissing, S., Bach-Mortensen, P., Juul, A., Bräuner-Osborne, H., Lanske, B. & Blomberg Jensen, M., 2021, In: The Journal of clinical endocrinology and metabolism. 106, 4, p. e1775-e1792

  Research output: Contribution to journal › Journal article › Research › peer-review
  14 Citations (Scopus)

• THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein-coupled receptors

  Alexander, S. P., Christopoulos, A., Davenport, A. P., Kelly, E., Mathie, A., Peters, J. A., Veale, E. L., Armstrong, J. F., Faccenda, E., Harding, S. D., Pawson, A. J., Southan, C., Davies, J. A., Abbracchio, M. P., Alexander, W., Al-Hosaini, K., Bäck, M., Barnes, N. M., Bathgate, R., Beaulieu, J-M. & 135 others, Bernstein, K. E., Bettler, B., Birdsall, N. J. M., Blaho, V., Boulay, F., Bousquet, C., Bräuner-Osborne, H., Burnstock, G., Caló, G., Castaño, J. P., Catt, K. J., Ceruti, S., Chazot, P., Chiang, N., Chini, B., Chun, J., Cianciulli, A., Civelli, O., Clapp, L. H., Couture, R., Csaba, Z., Dahlgren, C., Dent, G., Singh, K. D., Douglas, S. D., Dournaud, P., Eguchi, S., Escher, E., Filardo, E. J., Fong, T., Fumagalli, M., Gainetdinov, R. R., Gasparo, M. D., Gerard, C., Gershengorn, M., Gobeil, F., Goodfriend, T. L., Goudet, C., Gregory, K. J., Gundlach, A. L., Hamann, J., Hanson, J., Hauger, R. L., Hay, D. L., Heinemann, A., Hollenberg, M. D., Holliday, N. D., Horiuchi, M., Hoyer, D., Hunyady, L., Husain, A., IJzerman, A. P., Inagami, T., Jacobson, K. A., Jensen, R. T., Jockers, R., Jonnalagadda, D., Karnik, S., Kaupmann, K., Kemp, J., Kennedy, C., Kihara, Y., Kitazawa, T., Kozielewicz, P., Kreienkamp, H-J., Kukkonen, J. P., Langenhan, T., Leach, K., Lecca, D., Lee, J. D., Leeman, S. E., Leprince, J., Li, X. X., Williams, T. L., Lolait, S. J., Lupp, A., Macrae, R., Maguire, J., Mazella, J., McArdle, C. A., Melmed, S., Michel, M. C., Miller, L. J., Mitolo, V., Mouillac, B., Müller, C. E., Murphy, P., Nahon, J-L., Ngo, T., Norel, X., Nyimanu, D., O'Carroll, A-M., Offermanns, S., Panaro, M. A., Parmentier, M., Pertwee, R. G., Pin, J-P., Prossnitz, E. R., Quinn, M., Ramachandran, R., Ray, M., Reinscheid, R. K., Rondard, P., Rovati, G. E., Ruzza, C., Sanger, G. J., Schöneberg, T., Schulte, G., Schulz, S., Segaloff, D. L., Serhan, C. N., Stoddart, L. A., Sugimoto, Y., Summers, R., Tan, V. P., Thal, D., Thomas, W. W., Timmermans, P. B. M. W. M., Tirupula, K., Tulipano, G., Unal, H., Unger, T., Valant, C., Vanderheyden, P., Vaudry, D., Vaudry, H., Vilardaga, J-P., Walker, C. S., Wang, J. M., Ward, D. T., Wester, H-J., Willars, G. B., Woodruff, T. M., Yao, C. & Ye, R. D., 2021, In: British Journal of Pharmacology. 178 , S1, p. S27-S156

  Research output: Contribution to journal › Journal article › Research › peer-review

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  421 Citations (Scopus)

  14 Downloads (Pure)
• 2020

  Biased agonism of clinically approved μ-opioid receptor agonists and TRV130 is not controlled by binding and signaling kinetics

  Pedersen, M. F., Wrobel, T. M., Märcher-Rørsted, E., Pedersen, D. S., Møller, T. C., Gabriele, F., Pedersen, H., Matosiuk, D., Foster, S. R., Bouvier, M. & Bräuner-Osborne, H., 2020, In: Neuropharmacology. 166, 13 p., 107718.

  Research output: Contribution to journal › Journal article › Research › peer-review

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  54 Citations (Scopus)

  181 Downloads (Pure)

• Delineation of molecular determinants for FR900359 inhibition of G_q/11 unlocks inhibition of Gα_s

  Boesgaard, M. W., Harpsøe, K., Malmberg, M., Underwood, C. R., Inoue, A., Mathiesen, J. M., König, G. M., Kostenis, E., Gloriam, D. E. & Bräuner-Osborne, H., 2020, In: Journal of Biological Chemistry. 295, 40, p. 13850-13861

  Research output: Contribution to journal › Journal article › Research › peer-review

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  13 Citations (Scopus)

  27 Downloads (Pure)

• Detailed in vitro pharmacological characterization of clinically tested negative allosteric modulators of the metabotropic glutamate receptor 5 (mGlu5)

  Arsova, A., Møller, T. C., Vedel, L., Hansen, J. L., Foster, S. R., Gregory, K. J. & Bräuner-Osborne, H., 2020, In: Molecular Pharmacology. 98, 1, p. 49-60

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access
  12 Citations (Scopus)

• Dissecting the roles of GRK2 and GRK3 in μ-opioid receptor internalization and β-arrestin2 recruitment using CRISPR/Cas9-edited HEK293 cells

  Møller, T. C., Pedersen, M. F., van Senten, J. R., Seiersen, S. D., Mathiesen, J. M., Bouvier, M. & Bräuner-Osborne, H., 2020, In: Scientific Reports. 10, 1, 13 p., 17395.

  Research output: Contribution to journal › Journal article › Research › peer-review

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  33 Citations (Scopus)

  48 Downloads (Pure)

• Enhanced agonist residence time, internalization rate and signalling of the GIP receptor variant [E354Q] facilitate receptor desensitization and long-term impairment of the GIP system

  Gabe, M. B. N., van der Velden, W. J. C., Gadgaard, S., Smit, F. X., Hartmann, B., Bräuner-Osborne, H. & Rosenkilde, M. M., 2020, In: Basic & Clinical Pharmacology & Toxicology. 126, p. 122-132

  Research output: Contribution to journal › Journal article › Research › peer-review

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  28 Citations (Scopus)

  81 Downloads (Pure)

• G protein-coupled receptor pharmacology-The next generation

  Bräuner-Osborne, H., Rosenkilde, M. M., Gether, U. & Gloriam, D. E., 2020, In: Basic & Clinical Pharmacology & Toxicology. 126, Supplement 6, p. 3-4 2 p.

  Research output: Contribution to journal › Editorial › Research
  2 Citations (Scopus)

• Heterozygous Mutation (Q459R) in the Calcium-Sensing Receptor Gene Causes Familial Hypocalciuric Hypercalcemia 1 (FHH1)

  Boisen, I. M., Mos, I., Lerche-Black, E. M., Juul, A., Bräuner-Osborne, H. & Blomberg Jensen, M., 1 Apr 2020, In: The Journal of clinical endocrinology and metabolism. 105, 4, p. e1322-e1330

  Research output: Contribution to journal › Journal article › Research › peer-review
  4 Citations (Scopus)

• International Union of Basic and Clinical Pharmacology. CVIII. Calcium-Sensing Receptor Nomenclature, Pharmacology, and Function

  Leach, K., Hannan, F. M., Josephs, T. M., Keller, A. N., Møller, T. C., Ward, D. T., Kallay, E., Mason, R. S., Thakker, R. V., Riccardi, D., Conigrave, A. D. & Bräuner-Osborne, H., Jul 2020, In: Pharmacological Reviews. 72, 3, p. 558-604 47 p.

  Research output: Contribution to journal › Review › Research › peer-review

  Open Access
  63 Citations (Scopus)

• Novel approaches leading towards peptide GPCR de-orphanisation

  Hauser, A. S., Gloriam, D. E., Bräuner-Osborne, H. & Foster, S. R., 1 Mar 2020, In: British Journal of Pharmacology. 177, 5, p. 961-968 8 p.

  Research output: Contribution to journal › Review › Research › peer-review

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  26 Citations (Scopus)

  140 Downloads (Pure)

• Pharmacology and physiological function of the orphan GPRC6A receptor

  Jorgensen, C. V. & Brauner-Osborne, H., 2020, In: Basic & Clinical Pharmacology & Toxicology. 126, p. 77-87 11 p.

  Research output: Contribution to journal › Review › Research › peer-review
  21 Citations (Scopus)

  32 Downloads (Pure)

• The selective 5-HT2A receptor agonist 25CN-NBOH: structure-activity relationship, in vivo pharmacology, and in vitro and ex vivo binding characteristics of [3H]25CN-NBOH

  Jensen, A. A., Halberstadt, A. L., Märcher-Rørsted, E., Odland, A. U., Chatha, M., Speth, N., Liebscher, G., Hansen, M., Bräuner-Osborne, H., Palner, M., Andreasen, J. T. & Kristensen, J. L., 2020, In: Biochemical Pharmacology. 177, 16 p., 113979.

  Research output: Contribution to journal › Journal article › Research › peer-review
  18 Citations (Scopus)
• 2019

  Calcium sensing receptor in male germ cells is essential for processes leading to fertilization

  Boisen, I. M., Jensen, M. B., Rehfeld, A., Nielsen, J. E., Juul, A., Mos, I., Brauner-Osborne, H. & Lanske, B., Dec 2019, p. 216-216.

  Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

• Calcium-Sensing Receptor Internalization Is β-Arrestin-Dependent and Modulated by Allosteric Ligands

  Mos, I., Jacobsen, S. E., Foster, S. R. & Bräuner-Osborne, H., Oct 2019, In: Molecular Pharmacology. 96, 4, p. 463-474 12 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

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  25 Citations (Scopus)

  152 Downloads (Pure)

• Discovery of Human Signaling Systems: Pairing Peptides to G Protein-Coupled Receptors

  Foster, S. R., Hauser, A. S., Vedel, L., Strachan, R. T., Huang, X-P., Gavin, A. C., Shah, S. D., Nayak, A. P., Haugaard-Kedström, L. M., Penn, R. B., Roth, B. L., Bräuner-Osborne, H. & Gloriam, D. E., 31 Oct 2019, In: Cell. 179, 4, p. 895-908

  Research output: Contribution to journal › Journal article › Research › peer-review

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  147 Citations (Scopus)

  256 Downloads (Pure)

• Identification of a novel scaffold for a small molecule GPR139 receptor agonist

  Nøhr, A. C., Shehata, M. A., Palmer, D., Pokhrel, R., Vallianou, M., Foster, S. R., Gentry, P. R., Gloriam, D. E. & Bräuner-Osborne, H., 7 Mar 2019, In: Scientific Reports. 9, 1, 10 p., 3802.

  Research output: Contribution to journal › Journal article › Research › peer-review

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  10 Citations (Scopus)

  81 Downloads (Pure)

• Label-free dynamic mass redistribution analysis of endogenous adrenergic receptor signaling in primary preadipocytes and differentiated adipocytes

  Jørgensen, C. V., Zhou, H., Seibel, M. J. & Bräuner-Osborne, H., 1 Apr 2019, In: Journal of Pharmacological and Toxicological Methods. 97, p. 59-66 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  1 Citation (Scopus)

• Metabolic and skeletal homeostasis are maintained in full locus GPRC6A knockout mice

  Jørgensen, C. V., Gasparini, S. J., Tu, J., Zhou, H., Seibel, M. J. & Bräuner-Osborne, H., 12 Apr 2019, In: Scientific Reports. 9, 1, 8 p., 5995.

  Research output: Contribution to journal › Journal article › Research › peer-review

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  18 Citations (Scopus)

  86 Downloads (Pure)

• Pharmacology and function of the orphan GPR139 G protein-coupled receptor

  Vedel, L., Nøhr, A. C., Gloriam, D. E. & Bräuner-Osborne, H., 27 May 2019, In: Basic & Clinical Pharmacology & Toxicology. 126, p. 35-46

  Research output: Contribution to journal › Review › Research › peer-review

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  15 Citations (Scopus)

  120 Downloads (Pure)

• Probing the Existence of a Metastable Binding Site at the β2-Adrenergic Receptor with Homobivalent Bitopic Ligands

  Gaiser, B. I., Danielsen, M., Marcher-Rørsted, E., Røpke Jørgensen, K., Wróbel, T. M., Frykman, M., Johansson, H., Bräuner-Osborne, H., Gloriam, D. E., Mathiesen, J. M. & Sejer Pedersen, D., 12 Sep 2019, In: Journal of Medicinal Chemistry. 62, 17, p. 7806-7839 34 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  14 Citations (Scopus)

• Rational design of a heterotrimeric G protein α subunit with artificial inhibitor sensitivity

  Malfacini, D., Patt, J., Annala, S., Harpsøe, K., Eryilmaz, F., Reher, R., Crüsemann, M., Hanke, W., Zhang, H., Tietze, D., Gloriam, D. E., Bräuner-Osborne, H., Strømgaard, K., König, G. M., Inoue, A., Gomeza, J. & Kostenis, E., 12 Apr 2019, In: The Journal of Biological Chemistry. 294, 15, p. 5747-5758

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  30 Citations (Scopus)

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• Structure–Activity Relationship Studies of the Natural Product G _q/11 Protein Inhibitor YM-254890

  Xiong, X. F., Zhang, H., Boesgaard, M. W., Underwood, C. R., Bräuner-Osborne, H. & Strømgaard, K., Apr 2019, In: ChemMedChem. 14, 8, p. 865-870

  Research output: Contribution to journal › Journal article › Research › peer-review
  21 Citations (Scopus)
• 2018

  Human GIP(3-30)NH inhibits G protein-dependent as well as G protein-independent signaling and is selective for the GIP receptor with high-affinity binding to primate but not rodent GIP receptors

  Gabe, M. B. N., Sparre-Ulrich, A. H., Pedersen, M. F., Gasbjerg, L. S., Inoue, A., Bräuner-Osborne, H., Hartmann, B. & Rosenkilde, M. M., 31 Jan 2018, In: Biochemical Pharmacology. 150, p. 97-107 11 p.

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  70 Citations (Scopus)

• Structure–activity relationship and conformational studies of the natural product cyclic depsipeptides YM-254890 and FR900359

  Zhang, H., Nielsen, A. L., Boesgaard, M. W., Harpsøe, K., Daly, N. L., Xiong, X., Underwood, C. R., Haugaard-kedström, L. M., Bräuner-osborne, H., Gloriam, D. E. & Strømgaard, K., 2018, In: European Journal of Medicinal Chemistry. 156, p. 847-860

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  25 Citations (Scopus)
• 2017

  Applying label-free dynamic mass redistribution assay for studying endogenous FPR1 receptor signalling in human neutrophils

  Christensen, H. B., Gloriam, D. E., Pedersen, D. S., Cowland, J. B., Borregaard, N. & Bräuner-Osborne, H., 15 Jul 2017, In: Journal of Pharmacological and Toxicological Methods. 88, Pt 1, p. 72-78 7 p.

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  11 Citations (Scopus)

• Detailed characterization of the in vitro pharmacological and pharmacokinetic properties of N-(2-hydroxybenzyl)-2,5-dimethoxy-4-cyanophenylethylamine (25CN-NBOH), a highly selective and brain-penetrant 5-HT2A receptor agonist

  Jensen, A. A., McCorvy, J. D., Petersen, S. L., Bundgaard, C., Liebscher, G., Kenakin, T. P., Bräuner-Osborne, H., Kehler, J. & Kristensen, J. L., 2017, In: Journal of Pharmacology and Experimental Therapeutics. 361, 3, p. 441-453

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  47 Citations (Scopus)

• Genetic Variations in the Human G Protein-coupled Receptor Class C, Group 6, Member A (GPRC6A) Control Cell Surface Expression and Function

  Jorgensen, S., Have, C. T., Underwood, C. R., Johansen, L. D., Wellendorph, P., Gjesing, A. P., Jorgensen, C. V., Quan, S., Rui, G., Inoue, A., Linneberg, A., Grarup, N., Jun, W., Pedersen, O., Hansen, T. & Bräuner-Osborne, H., 2017, In: The Journal of Biological Chemistry. 292, 4, p. 1524-1534 11 p.

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  23 Citations (Scopus)

• Identification of AICP as a GluN2C-Selective N-Methyl-d-Aspartate Receptor Superagonist at the GluN1 Glycine Site

  Jessen, M., Frederiksen, K., Yi, F., Clausen, R. P., Hansen, K. B., Bräuner-Osborne, H., Kilburn, J. P. & Damholt, A., Aug 2017, In: Molecular Pharmacology. 92, 2, p. 151-161 11 p.

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  16 Citations (Scopus)

• Identification of Histamine H3 Receptor Ligands Using a New Crystal Structure Fragment-based Method

  Frandsen, I. O., Boesgaard, M. W., Fidom, K., Hauser, A. S., Isberg, V., Bräuner-Osborne, H., Wellendorph, P. & Gloriam, D. E., 6 Jul 2017, In: Scientific Reports. 7, 1, 10 p., 4829.

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  10 Citations (Scopus)

  293 Downloads (Pure)