Harald S. Hansen

Search results

• 2024

  Metabolomic profiling and accurate diagnosis of basal cell carcinoma by MALDI imaging and machine learning

  Brorsen, L. F., McKenzie, J. S., Pinto, F. E., Glud, M., Hansen, H. S., Haedersdal, M., Takats, Z., Janfelt, C. & Lerche, C. M., 2024, In: Experimental Dermatology. 33, 7, 11 p., e15141.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  10 Downloads (Pure)
• 2022

  Vagal afferent cholecystokinin receptor activation is required for glucagon-like peptide-1–induced satiation

  Vana, V., Lærke, M. K., Rehfeld, J. F., Arnold, M., Dmytriyeva, O., Langhans, W., Schwartz, T. W. & Hansen, H. S., 2022, In: Diabetes, Obesity and Metabolism. 24, 2, p. 268-280

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  16 Citations (Scopus)

  34 Downloads (Pure)
• 2021

  Post-oral fat-induced satiation is mediated by endogenous CCK and GLP-1 in a fat self-administration mouse model

  Vana, V., Lærke, M. K., Kleberg, K., Mroz, P. A., Lindberg, B. L., Ekberg, J. H., Rehfeld, J. F., Schwartz, T. W. & Hansen, H. S., 2021, In: Physiology and Behavior. 234, 12 p., 113315.

  Research output: Contribution to journal › Journal article › Research › peer-review
  6 Citations (Scopus)
• 2020

  Data-enriched edible pharmaceuticals (DEEP) of medical cannabis by inkjet printing

  Öblom, H., Cornett, C., Bøtker, J., Frokjaer, S., Hansen, H., Rades, T., Rantanen, J. & Genina, N., 2020, In: International Journal of Pharmaceutics. 589, p. 1-11 119866.

  Research output: Contribution to journal › Journal article › Research › peer-review
  47 Citations (Scopus)

• Intestinal sensing and handling of dietary lipids in gastric bypass-operated patients and matched controls

  Martinussen, C., Dirksen, C., Bojsen-Møller, K. N., Svane, M. S., Carlsson, E. R., Hartmann, B., Clausen, T. R., Veedfald, S., Kristiansen, V. B., Rehfeld, J. F., Hansen, H. S., Holst, J. J. & Madsbad, S., 2020, In: American Journal of Clinical Nutrition. 111, 1, p. 28-41

  Research output: Contribution to journal › Journal article › Research › peer-review
  9 Citations (Scopus)

• Intrapulmonary (i.pulmon.) Pull Immunization With the Tuberculosis Subunit Vaccine Candidate H56/CAF01 After Intramuscular (i.m.) Priming Elicits a Distinct Innate Myeloid Response and Activation of Antigen-Presenting Cells Than i.m. or i.pulmon. Prime Immunization Alone

  Thakur, A., Pinto, F. E., Hansen, H. S., Andersen, P., Christensen, D., Janfelt, C. & Foged, C., 2020, In: Frontiers in Immunology. 11, p. 803

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  20 Citations (Scopus)

  90 Downloads (Pure)

• The autocrine role of FGF21 in cultured adipocytes

  Justesen, S., Haugegaard, K. V., Hansen, J. B., Hansen, H. S. & Andersen, B., 2020, In: The Biochemical journal. 477, 13, p. 2477-2487 11 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  16 Citations (Scopus)

  1 Downloads (Pure)
• 2019

  Essentiality of n-6 fatty acids

  Hansen, H. S., 26 Apr 2019, In: Journal of Biological Chemistry. 294, p. 6692 1 p.

  Research output: Contribution to journal › Journal article › Communication
  1 Citation (Scopus)

• Non-endocannabinoid N-acylethanolamines and 2-monoacylglycerols in the intestine

  Hansen, H. S. & Vana, V., May 2019, In: British Journal of Pharmacology. 176, 10, p. 1443-1454

  Research output: Contribution to journal › Review › peer-review

  Open Access
  31 Citations (Scopus)
• 2018

  Comparing olive oil and C4-dietary oil, a prodrug for the GPR119 agonist, 2-oleoyl glycerol, less energy intake of the latter is needed to stimulate incretin hormone secretion in overweight subjects with type 2 diabetes

  Mandøe, M. J., Hansen, K. B., Windeløv, J. A., Knop, F. K., Rehfeld, J. F., Rosenkilde, M. M., Holst, J. J. & Hansen, H. S., 1 Dec 2018, In: Nutrition and Diabetes. 8, 1, p. 1-10 2.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  13 Citations (Scopus)

  182 Downloads (Pure)

• Delivery of amitriptyline by intravenous and intraperitoneal administration compared in the same animal by whole-body mass spectrometry imaging of a stable isotope labelled drug substance in mice

  Morineau, L., Jacobsen, S. C., Kleberg, K., Hansen, H. S. & Janfelt, C., 2 Dec 2018, In: Expert Opinion on Drug Delivery. 15, 12, p. 1157-1163

  Research output: Contribution to journal › Journal article › Research › peer-review
  8 Citations (Scopus)
• 2017

  Gastric Bypass Surgery Recruits a Gut PPAR-α-Striatal D1R Pathway to Reduce Fat Appetite in Obese Rats

  Hankir, M. K., Seyfried, F., Hintschich, C. A., Diep, T.-A., Kleberg, K., Kranz, M., Deuther-Conrad, W., Tellez, L. A., Rullmann, M., Patt, M., Teichert, J., Hesse, S., Sabri, O., Brust, P., Hansen, H. S., de Araujo, I. E., Krügel, U. & Fenske, W. K., 7 Feb 2017, In: Cell Metabolism. 25, 2, p. 335-344 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  105 Citations (Scopus)
• 2016

  Biased signaling of lipids and allosteric actions of synthetic molecules for GPR119

  Hassing, H. A., Fares, S., Larsen, O., Pad, H., Pedersen, M. H., Jones, R. M., Schwartz, T. W., Hansen, H. S. & Rosenkilde, M. M., 26 Aug 2016, In: Biochemical Pharmacology. 119, 1, p. 66-75 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  46 Citations (Scopus)

  457 Downloads (Pure)

• Cryo-sectioning of mice for whole-body imaging of drugs and metabolites with desorption electrospray ionization mass spectrometry imaging - a simplified approach

  Okutan, S., Hansen, H. S. & Janfelt, C., Jun 2016, In: Proteomics. 16, 11-12, p. 1633-41 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  15 Citations (Scopus)

• GPR119 - a major Enteroendocrine Sensor of Dietary Triglyceride Metabolites Co-acting in Synergy with FFA1 (GPR40)

  Ekberg, J. H., Pedersen, M. H., Kristensen, L. V., Madsen, A. N., Engelstoft, M. S., Husted, A.-S., Sichlau, R., Egerod, K. L., Timshel, P., Kowalski, T. J., Gribble, F. M., Reiman, F., Hansen, H. S., Howard, A. D., Holst, B. & Schwartz, T. W., 25 Oct 2016, In: Endocrinology. 157, 12, p. 4561-4569 9 p., en20161334.

  Research output: Contribution to journal › Journal article › Research › peer-review
  87 Citations (Scopus)

• Mass spectrometry imaging of biomarker lipids for phagocytosis and signalling during focal cerebral ischaemia

  Nielsen, M. M. B., Lambertsen, K. L., Clausen, B. H., Meyer, M., Bhandari, D. R., Larsen, S. T., Poulsen, S. S., Spengler, B., Janfelt, C. & Hansen, H. S., 22 Dec 2016, In: Scientific Reports. 6, p. 1-14 14 p., 39571.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access
  70 Citations (Scopus)

• Opioid and cannabinoid receptors

  Clausen, R. P. & Hansen, H. S., 2016, Textbook of drug design and discovery. 5. ed. CRC Press, p. 329-346

  Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Education

• Oral 2-oleyl glyceryl ether improves glucose tolerance in mice through the GPR119 receptor

  Hassing, H. A., Engelstoft, M. S., Sichlau, R. M., Madsen, A. N., Rehfeld, J. F., Pedersen, J., Jones, R. M., Holst, J. J., Schwartz, T. W., Rosenkilde, M. M. & Hansen, H. S., 2016, In: BioFactors. 42, 6, p. 665-673

  Research output: Contribution to journal › Journal article › Research › peer-review
  26 Citations (Scopus)
• 2015

  Fedtstoffer

  Dyerberg, J., Hansen, H. S. & Stender, S., 2015, Menneskets Ernæring. Astrup, A., Bügel, S., Dyerberg, J. & Stender, S. (eds.). 4.udgave ed. København: Munksgaard , p. 99-117 19 p.

  Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Education › peer-review

• Non-endocannabinoid N-Acylethanolamines and Monoacylglycerols: Old Molecules New Targets

  Hansen, H. S., Kleberg, K. & Hassing, H. A., 2015, The Endocannabinoidome: The World of Endocannabinoids and Related Mediators. Di Marzo, V. & Wang, J. (eds.). Amsterdam, Vol. Elsevier. p. 1-13 13 p.

  Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  6 Citations (Scopus)

• Sensing of triacylglycerol in the gut: different mechanisms for fatty acids and 2-monoacylglycerol

  Kleberg, K., Jacobsen, A. K., Ferreira, J. G., Windeløv, J. A., Rehfeld, J. F., Holst, J. J., de Araujo, I. E. & Hansen, H. S., 16 Jan 2015, In: The Journal of Physiology. 593, 8, p. 2097-109 13 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  17 Citations (Scopus)

• The 2-monoacylglycerol moiety of dietary fat appears to be responsible for the fat-induced release of GLP-1 in humans.

  Mandøe, M. J., Hansen, K. B., Hartmann, B., Rehfeld, J. F., Holst, J. J. & Hansen, H. S., 2015, In: The American Journal of Clinical Nutrition. 102, 3, p. 548-555 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  61 Citations (Scopus)
• 2014

  Classical endocannabinoid-like compounds and their regulation by nutrients

  Kleberg, K., Hassing, H. A. & Hansen, H. S., 2014, In: BioFactors (Oxford, England). 40, 4, p. 363-372 10 p.

  Research output: Contribution to journal › Journal article › Research
  44 Citations (Scopus)

• Dietary non-esterified oleic Acid decreases the jejunal levels of anorectic N-acylethanolamines

  Diep, T. A., Madsen, A. N., Krogh-Hansen, S., Al-Shahwani, M., Al-Sabagh, L., Holst, B. & Hansen, H. S., 2014, In: PloS one. 9, 6, p. 1-7 7 p., e100365.

  Research output: Contribution to journal › Journal article › Research › peer-review

  File
  14 Citations (Scopus)

  4709 Downloads (Pure)

• Evaluation of the immediate vascular stability of lipoprotein lipase-generated 2-monoacylglycerol in mice

  Kleberg, K., Nielsen, L. L., Stuhr-Hansen, N., Nielsen, J. & Hansen, H. S., Nov 2014, In: BioFactors. 40, 6, p. 596-602 7 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  11 Citations (Scopus)

• Role of anorectic N-acylethanolamines in intestinal physiology and satiety control with respect to dietary fat

  Hansen, H. S., 28 Mar 2014, In: Pharmacological Research. 86, p. 18-25 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  54 Citations (Scopus)

• The PPARalpha agonist, fenofibrate decreases levels of anorectic N-acylethanolamines in the small intestine of mice

  Diep, T. A., Golbas, G. & Hansen, H. S., 28 Jun 2014. 1 p.

  Research output: Contribution to conference › Conference abstract for conference › Research
• 2013

  Comment on: Harte et al. High Fat Intake Leads to Acute Postprandial Exposure to Circulating Endotoxin in Type 2 Diabetic Subjects. Diabetes Care 2012;35:375-382

  Hansen, H. S., Moesby, L., Timm, M. & Hansen, E. W., Mar 2013, In: Diabetes Care. 36, 3, p. e42

  Research output: Contribution to journal › Comment/debate › Research › peer-review
  1 Citation (Scopus)

• Displaced dual-mode imaging with desorption electrospray ionization for simultaneous mass spectrometry imaging in both polarities and with several scan modes

  Janfelt, C., Wellner, N., Hansen, H. S. & Hansen, S. H., Mar 2013, In: Journal of Mass Spectrometry. 48, 3, p. 361-6 6 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  20 Citations (Scopus)

• Effect of diet on tissue levels of palmitoylethanolamide

  Hansen, H. S., 1 Feb 2013, In: C N S & Neurological Disorders - Drug Targets. 12, 1, p. 17-25 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  23 Citations (Scopus)

• N-acylation of phosphatidylethanolamine and its biological functions in mammals

  Wellner, N., Diep, T. A., Janfelt, C. & Hansen, H. S., Mar 2013, In: BBA General Subjects. 1831, 3, p. 652-62 11 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  85 Citations (Scopus)
• 2012

  GPR119 as a fat sensor

  Hansen, H. S., Rosenkilde, M. M., Holst, J. J. & Schwartz, T. W., Jul 2012, In: Trends in Pharmacological Sciences. 33, 7, p. 374-81 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  170 Citations (Scopus)

• Incretin hormones in patients with type 2 diabetes are increased by diet-oil, a pro-drug for the GPR 119 receptor agonist, 2-oleoyl-glycerol

  Mandoe, M. J., Hansen, K. B., Knop, F. K., Holst, J. J. & Hansen, H. S., Oct 2012, In: Diabetologia. 55, p. S340-S340

  Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

• Ischemia in neonatal rat brains analyzed by Desorption Electrospray Ionization Imaging mass spectrometry

  Janfelt, C., Wellner, N., Leger, P.-L., Kokesch-Himmelreich, J., Hansen, S. H., Charriaut-Marlangue, C. & Hansen, H. S., 2012.

  Research output: Contribution to conference › Poster › Research › peer-review

• Metformin stimulates FGF21 expression in primary hepatocytes

  Nygaard, E. B., Vienberg, S. G., Ørskov, C., Hansen, H. S. & Andersen, B., 2012, In: Experimental Diabetes Research. 2012, p. 465282 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  53 Citations (Scopus)

• Visualization by mass spectrometry of 2-dimensional changes in rat brain lipids, including N-acylphosphatidylethanolamines, during neonatal brain ischemia

  Janfelt, C., Wellner, N., Leger, P.-L., Kokesch-Himmelreich, J., Hansen, S. H., Charriaut-Marlangue, C. & Hansen, H. S., 2012, In: F A S E B Journal. 26, 6, p. 2667-2673

  Research output: Contribution to journal › Journal article › Research › peer-review
  52 Citations (Scopus)
• 2011

  2-Oleoyl glycerol is a GPR119 agonist and signals GLP-1 release in humans

  Hansen, K. B., Rosenkilde, M. M., Knop, F. K., Wellner, N., Diep, T. A., Rehfeld, J. F., Andersen, U. B., Holst, J. J. & Hansen, H. S., 2011, In: Journal of Clinical Endocrinology and Metabolism. 96, 9, p. E1409-17

  Research output: Contribution to journal › Journal article › Research › peer-review
  239 Citations (Scopus)

• Dietary fat decreases intestinal levels of the anorectic lipids through a fat sensor

  Diep, T. A., Madsen, A. N., Holst, B., Kristiansen, M. M., Andersen, N. W., Hansen, S. H. & Hansen, H. S., 2011, In: The FASEB Journal. 25, 2, p. 765-774

  Research output: Contribution to journal › Journal article › Research › peer-review
  97 Citations (Scopus)

• Investigations of the human endocannabinoid system in two subcutaneous adipose tissue depots in lean subjects and in obese subjects before and after weight loss

  Bennetzen, M. F., Wellner, N., Ahmed, S. S. U., Ahmed, S. M., Diep, T. A., Hansen, H. S., Richelsen, B. & Pedersen, S. B., 2011, In: International Journal of Obesity. 35, 11, p. 1377-84 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  37 Citations (Scopus)

• Locked nucleic acid antisense oligonucleotides in treatment of hypercholesterolemia

  Nielsen, N. F., 2011, København: Københavns Universitet. 84 p.

  Research output: Book/Report › Ph.D. thesis

• Massespektrometri viser fordelingen af lægemiddelstoffer i planter og væv

  Janfelt, C., Thunig, J., Li, B., Andersen, N. W., Hansen, H. S. & Hansen, S. H., Dec 2011, In: Lægemiddelforskning. 2011, p. 10-12

  Research output: Contribution to journal › Journal article › Communication

  Open Access

  File
  1958 Downloads (Pure)

• Studies on the anorectic effect of N-acylphosphatidylethanolamine and phosphatidylethanolamine in mice

  Wellner, N., Tsuboi, K., Madsen, A. N., Holst, B., Diep, T. A., Nakao, M., Tokumura, A., Burns, M. P., Deutsch, D. G., Ueda, N. & Hansen, H. S., 1 Sept 2011, In: BBA General Subjects. 1811, 9, p. 508-12 5 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  17 Citations (Scopus)
• 2010

  Effect of the cannabinoid receptor-1 antagonist rimonabant on lipolysis in rats

  Mølhøj, S., Hansen, H. S., Schweiger, M., Zimmermann, R., Johansen, T. & Malmlöf, K., 2010, In: European Journal of Pharmacology. 646, 1-3, p. 38-45

  Research output: Contribution to journal › Journal article › Research › peer-review
  29 Citations (Scopus)

• Fedtstoffer

  Dyerberg, J., Hansen, H. S. & Stender, S., 2010, Menneskets ernæring. Astrup, A., Bügel, S., Dyerberg, J. & Stender, S. (eds.). 3. udgave ed. København: Munksgaard , p. 93-109 17 p.

  Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Education

• High fat diet influences N-acetylethanolamide formation in the intestine

  Diep, T. A., Kristiansen, M. M., Hansen, S. & Hansen, H. S., 2010.

  Research output: Contribution to conference › Poster › Research

• International Union of Basic and Clinical Pharmacology. LXXIX. Cannabinoid receptors and their ligands: beyond CB1 and CB2

  Pertwee, R. G., Howlett, A. C., Abood, M. E., Alexander, S. P. H., Di Marzo, V., Elphick, M. R., Greasley, P. J., Hansen, H. S., Kunos, G., Mackie, K., Mechoulam, R. & Ross, R. A., 1 Dec 2010, In: Pharmacological Reviews. 62, 4, p. 588-631 44 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  1434 Citations (Scopus)

• Long-term characterization of the diet-induced obese and diet-resistant rat model: a polygenetic rat model mimicking the human obesity syndrome

  Madsen, A. N., Hansen, G., Paulsen, S. J., Lykkegaard, K., Christensen, M. T., Hansen, H. S., Levin, B. E., Larsen, P. J., Knudsen, L. B., Fosgerau, K. & Vrang, N., 1 Sept 2010, In: Journal of Endocrinology. 206, 3, p. 287-96 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  130 Citations (Scopus)

• Opioid and cannabinoid receptors

  Clausen, R. P. & Hansen, H. S., 2010, Textbook of drug design and discovery. Krogsgaard-Larsen, P., Strømgaard, K. & Madsen, U. (eds.). 4 ed. Boca Raton: CRC Press, p. 313-328

  Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Education

• Palmitoylethanolamide and other anandamide congeners. Proposed role in the diseased brain

  Hansen, H. S., 1 Jul 2010, In: Experimental Neurology. 224, 1, p. 48-55 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  114 Citations (Scopus)

• Pitfalls in the sample preparation and analysis of N-acylethanolamines

  Skonberg, C., Artmann, A., Cornett, C., Hansen, S. H. & Hansen, H. S., 2010, In: Journal of Lipid Research. 51, p. 3062-3073

  Research output: Contribution to journal › Journal article › Research › peer-review
  19 Citations (Scopus)