Helle Hansson

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• 2024

  A novel computational pipeline for var gene expression augments the discovery of changes in the Plasmodium falciparum transcriptome during transition from in vivo to short-term in vitro culture

  Andradi-Brown, C., Wichers-Misterek, J. S., von Thien, H., Höppner, Y. D., Scholz, J. A. M., Hansson, H., Filtenborg Hocke, E., Gilberger, T. W., Duffy, M. F., Lavstsen, T., Baum, J., Otto, T. D., Cunnington, A. J. & Bachmann, A., 25 Jan 2024, In: eLife. 12, 38 p., RP87726.

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• Identification of the PfK13 mutations R561H and P441L in the Democratic Republic of Congo

  Mesia Kahunu, G., Wellmann Thomsen, S., Wellmann Thomsen, L., Muhindo Mavoko, H., Mitashi Mulopo, P., Filtenborg Hocke, E., Mandoko Nkoli, P., Baraka, V., Minja, D. T. R., Mousa, A., Roper, C., Mbongi Moke, D., Mumba Ngoyi, D., Mukomena Sompwe, E., Muyembe Tanfum, J. J., Hansson, H. & Alifrangis, M., 2024, In: International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases. 139, p. 41-49 9 p.

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• Lack of selection of antimalarial drug resistance markers after intermittent preventive treatment of schoolchildren (IPTsc) against malaria in northeastern Tanzania

  Von Wowern, F., Makenga, G., Wellmann Thomsen, S., Wellmann Thomsen, L., Filtenborg Hocke, E., Baraka, V., Opot, B. H., Minja, D. T. R., Lusingu, J. P. A., Van-geertruyden, J. P., Hansson, H. & Alifrangis, M., 2024, In: International Journal of Infectious Diseases. 146, 6 p., 107102.

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• Measuring protective efficacy and quantifying the impact of drug resistance: A novel malaria chemoprevention trial design and methodology

  Mousa, A., Cuomo-Dannenburg, G., Thompson, H. A., Chico, R. M., Beshir, K. B., Sutherland, C. J., Schellenberg, D., Gosling, R., Alifrangis, M., Hocke, E. F., Hansson, H., Chopo-Pizarro, A., Mbacham, W. F., Ali, I. M., Chaponda, M., Roper, C. & Okell, L. C., 2024, In: PLoS Medicine. 21, 5, 18 p., e1004376.

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• Parasite clearance and protection from Plasmodium falciparum infection (PCPI): a three-arm, parallel, double-blinded, placebo-controlled, randomised trial of presumptive sulfadoxine-pyrimethamine versus sulfadoxine-pyrimethamine plus amodiaquine versus artesunate monotherapy among asymptomatic children 3-5 years of age in Cameroon

  Martinez-Vega, R., Mbacham, W. F., Ali, I., Nji, A., Mousa, A., Beshir, K. B., Chopo-Pizarro, A., Kaur, H., Okell, L., Hansson, H., Hocke, E. F., Alifrangis, M., Gosling, R., Roper, C., Sutherland, C. & Chico, R. M., 26 Sep 2024, In: BMC Infectious Diseases. 24, 1, 1028.

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• Seasonal malaria chemoprevention therapy in children up to 9 years of age: Protocol for a cluster-randomized trial study

  Toure, M., Shaffer, J. G., Sanogo, D., Keita, S., Keita, M., Kane, F., Traore, B., Dabitao, D., Kone, A., Doumbia, C. O., Keating, J., Yukich, J., Hansson, H. H., Barry, A. E., Diakité, M., Alifrangis, M. & Doumbia, S., 2024, In: JMIR Research Protocols. 13, 9 p., e51660.

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• 2023

  A snapshot of the prevalence of dihydropteroate synthase-431V mutation and other sulfadoxine-pyrimethamine resistance markers in Plasmodium falciparum isolates in Nigeria

  Adegbola, A. J., Ijarotimi, O. A., Ubom, A. E., Adesoji, B. A., Babalola, O. E., Hocke, E. F., Hansson, H., Mousa, A., Bolaji, O. O., Alifrangis, M. & Roper, C., 2023, In: Malaria Journal. 22, 71.

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• Assessment of artemisinin tolerance in Plasmodium falciparum clinical isolates in children with uncomplicated malaria in Ghana

  Ahorhorlu, S. Y., Quashie, N. B., Jensen, R. W., Kudzi, W., Nartey, E. T., Duah-Quashie, N. O., Zoiku, F., Dzudzor, B., Wang, C. W., Hansson, H., Alifrangis, M. & Adjei, G. O., 2023, In: Malaria Journal. 22, 58.

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• Effect of monthly intermittent preventive treatment with dihydroartemisinin-piperaquine with and without azithromycin versus monthly sulfadoxine-pyrimethamine on adverse pregnancy outcomes in Africa: a double-blind randomised, partly placebo-controlled trial

  Madanitsa, M., Barsosio, H. C., Minja, D. T. R., Mtove, G., Kavishe, R. A., Dodd, J., Saidi, Q., Onyango, E. D., Otieno, K., Wang, D., Ashorn, U., Hill, J., Mukerebe, C., Gesase, S., Msemo, O. A., Mwapasa, V., Phiri, K. S., Maleta, K., Klein, N., Magnussen, P. & 9 others, Lusingu, J. P. A., Kariuki, S., Mosha, J. F., Alifrangis, M., Hansson, H., Schmiegelow, C., Gutman, J. R., Chico, R. M. & Ter Kuile, F. O., 2023, In: The Lancet. 401, 10381, p. 1020-1036 17 p.

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• Evolution of Plasmodium falciparum antimalarial drug resistance markers post-adoption of artemisinin-based combination therapies in Yaounde, Cameroon

  Niba, P. T. N., Nji, A. M., Chedjou, J. P. K., Hansson, H., Hocke, E. F., Ali, I. M., Achonduh-Atijegbe, O., Evehe, M. S. B., Jørgensen, M. H. M., Fomboh, C. T., Cui, L., Stresman, G., Bigoga, J. D., Alifrangis, M. & Mbacham, W. F., 2023, In: International Journal of Infectious Diseases. 132, p. 108-117 10 p.

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• Fetal growth and birth weight are independently reduced by malaria infection and curable sexually transmitted and reproductive tract infections in Kenya, Tanzania, and Malawi: A pregnancy cohort study

  Mtove, G., Chico, R. M., Madanitsa, M., Barsosio, H. C., Msemo, O. A., Saidi, Q., Gore-Langton, G. R., Minja, D. T. R., Mukerebe, C., Gesase, S., Mwapasa, V., Phiri, K. S., Hansson, H., Dodd, J., Magnussen, P., Kavishe, R. A., Mosha, F., Kariuki, S., Lusingu, J. P. A., Gutman, J. R. & 3 others, Alifrangis, M., Ter Kuile, F. O. & Schmiegelow, C., 2023, In: International Journal of Infectious Diseases. 135, p. 28-40 13 p.

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  5 Citations (Scopus)
• 2022

  Attributable risk factors for asymptomatic malaria and anaemia and their association with cognitive and psychomotor functions in schoolchildren of north-eastern Tanzania

  Makenga, G., Baraka, V., Francis, F., Minja, D. T. R., Gesase, S., Kyaruzi, E., Mtove, G., Nakato, S., Madebe, R., Søeborg, S. R., Langhoff, K. H., Hansson, H. S., Alifrangis, M., Lusingu, J. P. A. & Van Geertruyden, J-P., 2022, In: PLoS ONE. 17, 5, e0268654.

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  8 Citations (Scopus)

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• High DDT resistance without apparent association to kdr and Glutathione-S-transferase (GST) gene mutations in Aedes aegypti population at hotel compounds in Zanzibar

  Kampango, A., Hocke, E. F., Hansson, H., Furu, P., Haji, K. A., David, J-P., Konradsen, F., Saleh, F., Weldon, C. W., Schiøler, K. L. & Alifrangis, M., 2022, In: PLOS Neglected Tropical Diseases . 16, 5, 17 p., e0010355.

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  3 Citations (Scopus)

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• Preservation and extraction of malaria parasite DNA from dried blood spots

  Hansson, H., Saidi, Q. & Alifrangis, M., 2022, Malaria Immunology: Targeting the Surface of Infected Erythrocytes. Human Kinetics, Vol. 2470. p. 27-36 10 p. (Methods in molecular biology (Clifton, N.J.)).

  Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
  3 Citations (Scopus)
• 2021

  Common virulence gene expression in adult first-time infected malaria patients and severe cases

  Wichers, J. S., Tonkin-Hill, G., Thye, T., Krumkamp, R., Kreuels, B., Strauss, J., von Thien, H., Scholz, J. A. M., Smedegaard Hansson, H., Weisel Jensen, R., Turner, L., Lorenz, F-R., Schöllhorn, A., Bruchhaus, I., Tannich, E., Fendel, R., D Otto, T., Lavstsen, T., Gilberger, T. W., Duffy, M. & 1 others, Bachmann, A., 2021, In: eLife. 10, e69040.

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• Identification of single-nucleotide polymorphisms in the mitochondrial genome and kelch 13 gene of Plasmodium falciparum in different geographical populations

  Nydahl, T. K., Ahorhorlu, S. Y., Ndiaye, M., Das, M. K., Hansson, H., Bravo, M. C., Wang, C. W., Lusingu, J., Theisen, M., Singh, S. K., Singh, S., Campino, S., Lund, O., Roper, C. & Alifrangis, M., 2021, In: American Journal of Tropical Medicine and Hygiene. 105, 4, p. 1085-1092 8 p.

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• Reduced birth weight caused by sextuple drug resistant Plasmodium falciparum infection in early second trimester

  Hansson, H., Minja, D. T. R., Moeller, S. L., Lusingu, J. P. A., Bygbjerg, I. C., Yde, A-M., Jensen, R. W., Nag, S., Msemo, O. A., Theander, T. G., Alifrangis, M. & Schmiegelow, C., 2021, In: The Journal of Infectious Diseases. 224, 9, p. 1605–1613

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  5 Citations (Scopus)

• Ultrasensitive qPCR-Based Detection of Plasmodium falciparum in Pregnant Women Using Dried Blood or Whole Blood Pellet Samples Processed through Different DNA Extraction Methods

  Saidi, Q., Minja, D., Njau, J., Hansson, H., Kavishe, R. & Alifrangis, M., 2021, In: The American journal of tropical medicine and hygiene. 106, 3, p. 846-849 4 p.

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• 2020

  Gene expression profiling of malaria parasites reveals common virulence gene expression in adult first-time infected patients and severe cases

  Wichers, J. S., Tonkin-Hill, G., Thye, T., Krumkamp, R., Kreuels, B., Strauss, J., Thien, H. V., Scholz, J. A. M., Hansson, H. S., Jensen, R. W., Turner, L., Lorenz, F-R., Schöllhorn, A., Bruchhaus, I., Tannich, E., Fendel, R., Otto, T. D., Lavstsen, T., Gilberger, T-W., Duffy, M. F. & 1 others, Bachmann, A., 2020, bioRxiv.

  Research output: Working paper › Preprint › Research

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• 2019

  First-in-human, randomized, double-blind clinical trial of differentially adjuvanted PAMVAC, a vaccine candidate to prevent pregnancy-associated malaria

  Mordmüller, B., Sulyok, M., Egger-Adam, D., Resende, M., de Jongh, W. A., Jensen, M. H., Smedegaard, H. H., Ditlev, S. B., Soegaard, M., Poulsen, L., Dyring, C., Calle, C. L., Knoblich, A., Ibáñez, J., Esen, M., Deloron, P., Ndam, N., Issifou, S., Houard, S., Howard, R. F. & 7 others, Reed, S. G., Leroy, O., Luty, A. J. F., Theander, T. G., Kremsner, P. G., Salanti, A. & Nielsen, M. A., 2019, In: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 69, 9, p. 1509-1516 8 p.

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• Temporal pattern of mutations in the knockdown resistance (kdr) gene of Aedes aegypti mosquitoes sampled from Southern Taiwan

  Biduda, S., Lin, C-H., Saleh, F., Konradsen, F., Hansson, H., Schiøler, K. L. & Alifrangis, M., 2019, In: American Journal of Tropical Medicine and Hygiene. 101, 5, p. 973-975 3 p.

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• 2015

  Haplotypes of the endothelial protein C receptor (EPCR) gene are not associated with severe malaria in Tanzania

  Hansson, H. H., Turner, L., Møller, L., Wang, C. W., Minja, D., Gesase, S., Mmbando, B., Bygbjerg, I. C., Theander, T. G., Lusingu, J. P. A., Alifrangis, M. & Lavstsen, T., 2015, In: Malaria Journal. 14, 9 p., 474.

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  9 Citations (Scopus)

• Polymorphisms in the Haem Oxygenase-1 promoter are not associated with severity of Plasmodium falciparum malaria in Ghanaian children

  Hansson, H. H., Sørensen, L. M., Balle, C., Goka, B. Q., Luzon, E., Nkrumah, F. N., Schousboe, M. L., Rodrigues, O. P., Bygbjerg, I. C., Kurtzhals, J. A., Alifrangis, M. & Hempel, C., 2015, In: Malaria Journal. 14, 9 p., 153.

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  12 Citations (Scopus)
• 2013

  Genotyping Plasmodium vivax isolates from the 2011 outbreak in Greece

  Spanakos, G., Alifrangis, M., Schousboe, M. L., Patsoula, E., Tegos, N., Hansson, H. H., Bygbjerg, I. C., Vakalis, N. C., Tseroni, M., Kremastinou, J. & Hadjichristodoulou, C., 27 Dec 2013, In: Malaria Journal. 12, 1, p. 463

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  16 Citations (Scopus)

• Human genetic polymorphisms in the Knops blood group are not associated with a protective advantage against Plasmodium falciparum malaria in Southern Ghana

  Hansson, H. H., Kurtzhals, J. A., Goka, B. Q., Rodriques, O. P., Nkrumah, F. N., Theander, T. G., Bygbjerg, I. C. & Alifrangis, M., 7 Nov 2013, In: Malaria Journal. 12, 1, p. 400

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  19 Citations (Scopus)

• Rapid selection of Plasmodium falciparum chloroquine resistance transporter gene and multidrug resistance gene-1 haplotypes associated with past chloroquine and present artemether-lumefantrine use in Inhambane District, southern Mozambique

  Thomsen, T. T., Madsen, L. B., Hansson, H. H., Tomás, E. V. E., Charlwood, D., Bygbjerg, I. C. & Alifrangis, M., Mar 2013, In: American Journal of Tropical Medicine and Hygiene. 88, 3, p. 536-41 6 p.

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  44 Citations (Scopus)
• 2012

  The association between malaria parasitaemia, erythrocyte polymorphisms, malnutrition and anaemia in children less than 10 years in Senegal: a case control study

  Tine, R. C. K., Ndiaye, M., Hansson, H. H., Ndour, C. T., Faye, B., Alifrangis, M., Sylla, K., Ndiaye, J. L., Magnussen, P., Bygbjerg, I. C. & Gaye, O., 2012, In: BMC Research Notes. 5, 1, p. 565 1 p.

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• The association between malaria parasitemia, erythrocyte polymorphisms, malnutrition and anaemia in children less than 10 years in Senegal: a case control study

  Tine, R. C., Hansson, H. H., Ndiaye, M., Alifrangis, M., Faye, B., Ndour, C. T., Ndiaye, J. L., Magnussen, P., Bygbjerg, I. C. & Gaye, O., 2012. 1 p.

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• 2006

  Coccidiose i danske lam: - to case studier

  Hempel Olsen, C., Petersen, H. H., Hansson, H. H., Thamsborg, S. M. & Maddox-Hyttel, C., 2006, In: Dansk Veterinærtidsskrift. 89, 8, p. 26-30

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