Holger Grohganz

Holger Grohganz

Dr. scient, Associate Professor

  • Universitetsparken 2, 2100 København Ø

  • Universitetsparken 2

    2100 København Ø

  • Source: Scopus
20032024

Research activity per year

Personal profile

CV


Associate Professor, Department of Pharmaceutics and Analytical Chemistry, Faculty of Pharmaceutical Sciences, University of Copenhagen, since may 2011

Assistant Professor, Department of Pharmaceutics and Analytical Chemistry, Faculty of Pharmaceutical Sciences, University of Copenhagen, May 2007 April 2011
Associate Professor, Department of Health Sciences, Nord-Trøndelag University College, December 2004 - April 2007
Assistant Professor, Institute of Pharmacy, University of Tromsø, May 2002 - October 2002
Ph.D. Student, Institute of Pharmacy, University of Tromsø, September 1999 - April 2002 and November 2002 - November 2004
Scientific assistant, Institute of Pharmacy, University of Tromsø, February 1999 - August 1999
Registration as pharmacist, December 1998
Pre-registration period, November 1997 - October 1998
Exchange student, University of Utrecht, October 1996 - February 1997
Student of pharmacy, University of Erlangen-Nürnberg, November 1992 - October 1997

Primary fields of research

Research focusses on stabilizing the unstable, thereby addressing two major problems of new pharmacolically actuive substances: structural stability of macromolecules and poor water solubility of small organic molecules.

To address the low water solubility we transfrom drugs to their amorphous counterpart, which is more soluble. However, this form in unstable, which in turn is addressed by the formation of a co-amorphou form, which can posssess increased stability combined with increased solubility.

With reagrd to proteins and peptides, research focusses on an increase of the knowledge base related to freeze-drying.

The application of multivariate analysis, such as principal component analysis, and statisitical design of experiments is an integrated part of our reserach.

 

Keywords:

Peptides and Proteins in pharmaceutical formulations
Freeze-drying and spray-drying
Co-amorphous systems
Design of experiments, process analytical technology and quality by design

Teaching

Teaching covers the production, composition and quality assurance of solid dosage forms for drugs, such as tablets.

Courses:

Pharmacy 2 - Solid dosage forms

Bachelor project in Pharmacy

In addition, supervision of Master theses

Keywords

  • Former Faculty of Pharmaceutical Sciences

Collaborations and top research areas from the last five years

Recent external collaboration on country/territory level. Dive into details by clicking on the dots or