Research output per year
Research output per year
Personal profile
Education/Academic qualification
Pharmaceutical Sciences, PhD, University of Copenhagen
Feb 2018 → Jul 2021
Award Date: 5 Nov 2021
Chemistry, Master of Science, Federal University of Rio Grande do Sul, Porto Alegra, Rio Grande do Sul
Aug 2015 → Sep 2017
Award Date: 29 Sep 2017
Master of Science, Universidade Federal do Rio Grande do Sul
Award Date: 29 Sep 2017
Chemistry, Bachelor of Science, Federal University of Rio Grande do Sul, Porto Alegra, Rio Grande do Sul
Mar 2010 → Sep 2015
Award Date: 5 Sep 2015
Bachelor of Science, Universidade Federal do Rio Grande do Sul
Award Date: 5 Sep 2015
Ph.D., University of Copenhagen
External positions
Postdoctoral Researcher, Vrije Universiteit Amsterdam
1 Aug 2021 → 31 Jul 2023
Undergraduate Research Assistant, Northern Arizona University
1 Jan 2014 → 31 Dec 2014
Graduate Research Assistant, Universidade Federal do Rio Grande do Sul
Scientific Initiation Intern, Universidade Federal do Rio Grande do Sul
Keywords
- Faculty of Health and Medical Sciences
- Molecular modeling
- Molecular Dynamics
- Cheminformatics
- Medicinal Chemistry
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
-
Ligand selectivity hotspots in serotonin GPCRs
Simon, I. A., Bjørn-Yoshimoto, W. E., Harpsøe, K., Iliadis, S., Svensson, B., Jensen, A. A. & Gloriam, D. E., 2023, In: Trends in Pharmacological Sciences. 44, 12, p. 978-990Research output: Contribution to journal › Review › Research › peer-review
Open AccessFile5 Citations (Scopus)21 Downloads (Pure) -
Pharmacological Characterization and Radiolabeling of VUF15485, a High-Affinity Small-Molecule Agonist for the Atypical Chemokine Receptor ACKR3
Zarca, A. M., Adlere, I., Viciano, C. P., Arimont-Segura, M., Meyrath, M., Simon, I. A., Bebelman, J. P., Laan, D., Custers, H. G. J., Janssen, E., Versteegh, K. L., Buzink, M. C. M. L., Nesheva, D. N., Bosma, R., de Esch, I. J. P., Vischer, H. F., Wijtmans, M., Szpakowska, M., Chevigné, A., Hoffmann, C. & 5 others, , 2024, In: Molecular Pharmacology. 105, 4, p. 301-312 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
4 Citations (Scopus) -
PSW-Designer: An Open-Source Computational Platform for the Design and Virtual Screening of Photopharmacological Ligands
Simon, I. A., Homan, E. J., Wijtmans, M., Sundström, M., Leurs, R., De Esch, I. J. P. & Zarzycka, B. A., 2023, In: Journal of Chemical Information and Modeling. 63, 21, p. 6696-6705 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open Access -
Structure–Activity Assessment and In-Depth Analysis of Biased Agonism in a Set of Phenylalkylamine 5-HT2A Receptor Agonists
Pottie, E., Poulie, C. B. M., Simon, I. A., Harpsøe, K., D’Andrea, L., Komarov, I. V., Gloriam, D. E., Jensen, A. A., Kristensen, J. L. & Stove, C. P., 2023, In: ACS Chemical Neuroscience. 14, 15, p. 2727–2742Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile6 Citations (Scopus)21 Downloads (Pure) -
Discovery of β-Arrestin-Biased 25CN-NBOH-Derived 5-HT2A Receptor Agonists
Poulie, C. B. M., Pottie, E., Simon, I. A., Harpsøe, K., D'Andrea, L., Komarov, I. V., Gloriam, D. E., Jensen, A. A., Stove, C. P. & Kristensen, J. L., 2022, In: Journal of Medicinal Chemistry. 65, 18, p. 12031–12043Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile11 Citations (Scopus)49 Downloads (Pure) -
GPCRs steer Gi and Gs selectivity via TM5-TM6 switches as revealed by structures of serotonin receptors
Huang, S., Xu, P., Shen, D-D., Simon, I. A., Mao, C., Tan, Y., Zhang, H., Harpsøe, K., Li, H., Zhang, Y., You, C., Yu, X., Jiang, Y., Zhang, Y., Gloriam, D. E. & Xu, H. E., 2022, In: Molecular Cell. 82, 14, p. 2681-2695.e6 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile63 Citations (Scopus)13 Downloads (Pure) -
Structural insights into the lipid and ligand regulation of serotonin receptors
Xu, P., Huang, S., Zhang, H., Mao, C., Zhou, X. E., Cheng, X., Simon, I. A., Shen, D-D., Yen, H-Y., Robinson, C. V., Harpsøe, K., Svensson, B., Guo, J., Jiang, H., Gloriam, D. E., Melcher, K., Jiang, Y., Zhang, Y. & Xu, H. E., 2021, In: Nature. 592, p. 469-473Research output: Contribution to journal › Journal article › Research › peer-review
159 Citations (Scopus) -
CuO Nanofibers Immobilized on Paraffin-Impregnated Graphite Electrode and its Application in the Amperometric Detection of Glucose
Simon, I. A., Medeiros, N. G., Garcia, K. C., Soares, R. M. D., Rosa, A. T. & Silva, J. A., Aug 2015, In: Journal of the Brazilian Chemical Society. 26, 8, p. 1710-1717Research output: Contribution to journal › Journal article › Research › peer-review
8 Citations (Scopus)