Jacob Wium Bjerrum

Research output

Research output per year 2006 2007 2010 2013 2014 2022 2023 2024

• 1141 Citations
• 32 Journal article
• 5 Review
• 2 Editorial
• 1 Ph.D. thesis
• 3 More
  • 1 Book chapter
  • 1 Comment/debate
  • 1 Conference abstract in journal

Research output per year

Research output per year

Search results

• 2024

  Early Intestinal Ultrasound in Severe Ulcerative Colitis Identifies Patients at Increased Risk of 1-Year Treatment Failure and Colectomy

  Ilvemark, J. F. K. F., Wilkens, R., Thielsen, P., Dige, A., Boysen, T., Brynskov, J., Bjerrum, J. T. & Seidelin, J. B., 28 Jun 2024, (E-pub ahead of print) In: Journal of Crohn's & colitis. 11 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

• Non-TGFβ profibrotic signaling in ulcerative colitis after in vivo experimental intestinal injury in humans

  Seidelin, J. B., Bronze, M., Poulsen, A., Attauabi, M., Woetmann, A., Mead, B. E., Karp, J. M., Riis, L. B. & Bjerrum, J. T., 2024, In: American journal of physiology. Gastrointestinal and liver physiology. 327, 1, p. G70-G79 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

• Tarmultralydskanning ved kronisk inflammatorisk tarmsygdom

  Translated title of the contribution: Not AvailableBjerrum, J. W., Ilvemark, J., Seidelin, J. B. & Wilkens, R., 5 Feb 2024, In: Ugeskrift for Laeger. 186, 6, 9 p.

  Research output: Contribution to journal › Review › Research › peer-review

  Open Access

  File
  1 Downloads (Pure)
• 2023

  Distinct immune cell trigger responses in Ulcerative Colitis – Results from an in vivo human intestinal injury model

  Bronze, M., Johansen, J. V., Attauabi, M., Bjerrum, J. T., Ramírez Galera, M., Woetmann, A. & Benedict Seidelin, J., 2023, In: Journal of Crohn's and Colitis. 17, Supplement_1, p. i199-i200

  Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

• Editorial: safety and efficacy of infliximab and corticosteroids in checkpoint inhibitor-induced colitis—authors' reply

  Dahl, E. K., Abed, O. K., Kjeldsen, J., Donia, M., Svane, I. M., Dige, A., Agnholt, J. S., Bjerrum, J. T. & Seidelin, J. B., Jan 2023, In: Alimentary Pharmacology and Therapeutics. 57, 1, p. 152-153 2 p.

  Research output: Contribution to journal › Editorial › Research › peer-review
  1 Citation (Scopus)

• Letter: be careful of gastrointestinal CMV infection in adverse event from ICIs therapy in solid tumours — Authors' reply

  Dahl, E., Abed, O., Agnholt, J., Bjerrum, J., Dige, A., Kjeldsen, J., Svane, I., Donia, M. & Seidelin, J., 2023, In: Alimentary Pharmacology and Therapeutics. 57, 8, p. 918-919

  Research output: Contribution to journal › Comment/debate › Research › peer-review

• Rectal Cancer Risk After Colectomy in Patients With Inflammatory Bowel Disease—A Population-Based Danish Cohort Study 1978–2018

  Akimenko, E., Bjerrum, J. T., Iversen, A. T., Allin, K. H. & Jess, T., 2023, In: Gastro Hep Advances. 2, 6, p. 853-859 7 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  5 Downloads (Pure)
• 2022

  COLAR: open-label clinical study of IL-6 blockade with tocilizumab for the treatment of immune checkpoint inhibitor-induced colitis and arthritis

  Holmstroem, R. B., Nielsen, O. H., Jacobsen, S., Riis, L. B., Theile, S., Bjerrum, J. T., Vilmann, P., Johansen, J. S., Boisen, M. K., Eefsen, R. H. L., Marie Svane, I., Nielsen, D. L. & Chen, I. M., 2022, In: Journal for ImmunoTherapy of Cancer. 10, 9

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  24 Citations (Scopus)

  19 Downloads (Pure)

• Early intestinal ultrasound predicts intravenous corticosteroid response in hospitalized patients with severe ulcerative colitis

  Ilvemark, J. F. K. F., Wilkens, R., Thielsen, P., Dige, A., Boysen, T., Brynskov, J., Bjerrum, J. T. & Seidelin, J. B., 2022, In: Journal of Crohn's & colitis. 16, 11, p. 1725–1734

  Research output: Contribution to journal › Journal article › Research › peer-review
  18 Citations (Scopus)

• Influence of Genetics, Immunity and the Microbiome on the Prognosis of Inflammatory Bowel Disease (IBD Prognosis Study): the protocol for a Copenhagen IBD Inception Cohort Study

  Attauabi, M., Madsen, G. R., Bendtsen, F., Wewer, A. V., Wilkens, R., Ilvemark, J., Vladimirova, N., Jensen, A. B., Jensen, F. K., Hansen, S. B., Siebner, H. R., Nielsen, Y. J. W., Møller, J. M., Thomsen, H. S., Thomsen, S. F., Ingels, H. A. S., Theede, K., Boysen, T., Bjerrum, J. T., Jakobsen, C. & 13 others, Dorn-Rasmussen, M., Jansson, S., Yao, Y., Burian, E. A., Møller, F. T., Fana, V., Wiell, C., Terslev, L., Østergaard, M., Bertl, K., Stavropoulos, A., Seidelin, J. B. & Burisch, J., 2022, In: BMJ Open. 12, 6, e055779.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  23 Downloads (Pure)

• Lipidomic Trajectories Characterize Delayed Mucosal Wound Healing in Quiescent Ulcerative Colitis and Identify Potential Novel Therapeutic Targets

  Bjerrum, J. T., Wang, Y., Zhang, J., Riis, L. B., Nielsen, O. H. & Seidelin, J. B., 2022, In: International Journal of Biological Sciences. 18, 5, p. 1813-1828 16 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  5 Citations (Scopus)

  18 Downloads (Pure)

• Low-dose azathioprine and allopurinol versus azathioprine monotherapy in patients with ulcerative colitis (AAUC): An investigator-initiated, open, multicenter, parallel-arm, randomised controlled trial

  Kiszka-Kanowitz, M., Theede, K., Thomsen, S. B., Bjerrum, J. T., Brynskov, J., Gottschalck, I. B., Akimenko, E., Hilsted, K. L., Neumann, A., Wildt, S., Larsen, L., Munk, J. K., Ibsen, P. H., Janjua, H. G. R., Gluud, L. L. & Mertz-Nielsen, A., 2022, In: EClinicalMedicine. 45, 9 p., 101332.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  15 Citations (Scopus)

  14 Downloads (Pure)

• Praktisk anvendelse af thiopuriner hos patienter med kronisk inflammatoriske tarmsygdomme

  Translated title of the contribution: Practical guide to the use of thiopurinesin patients with inflammatory bowel diseasesZhao, M., Wewer, M. D., Bjerrum, J. T., Steenholdt, C., Schiødt, F., Haderslev, K., Kiszka-Kanowitz, M., Munkholm, P., Seidelin, J. & Burisch, J., 2022, In: Ugeskrift for Laeger. 184, 11, V09210706.

  Research output: Contribution to journal › Review › Research › peer-review

  Open Access

  File
  22 Downloads (Pure)

• Safety and efficacy of infliximab and corticosteroid therapy in checkpoint inhibitor-induced colitis

  Dahl, E. K., Abed, O. K., Kjeldsen, J., Donia, M., Svane, I. M., Dige, A., Agnholt, J. S., Bjerrum, J. T. & Seidelin, J. B., 2022, In: Alimentary Pharmacology and Therapeutics. 56, 9, p. 1370-1382 13 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  10 Citations (Scopus)

  7 Downloads (Pure)

• Tofacitinib and faecal microbiota transplantation in treating checkpoint inhibitor-induced enterocolitis: case report

  Holmstroem, R. B., Dahl, E. K., Helms, M., Nielsen, H. V., Andersen, J. B., Bjerrum, J. T., Svane, I. M., Ellebaek, E. & Seidelin, J. B., 2022, In: BMJ Open Gastroenterology. 9, 1, 4 p., e000989.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  9 Citations (Scopus)

  15 Downloads (Pure)
• 2021

  Acute Experimental Barrier Injury Triggers Ulcerative Colitis–Specific Innate Hyperresponsiveness and Ulcerative Colitis–Type Microbiome Changes in Humans

  Seidelin, J. B., Bahl, M. I., Licht, T. R., Mead, B. E., Karp, J. M., Johansen, J. V., Riis, L. B., Galera, M. R., Woetmann, A. & Bjerrum, J. T., 2021, In: Cellular and Molecular Gastroenterology and Hepatology. 12, 4, p. 1281-1296

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  7 Citations (Scopus)

  16 Downloads (Pure)

• IBD metabonomics predicts phenotype, disease course, and treatment response

  Bjerrum, J. T., Wang, Y. L., Seidelin, J. B. & Nielsen, O. H., 2021, In: EBioMedicine. 71, 103551.

  Research output: Contribution to journal › Review › Research › peer-review

  Open Access

  File
  20 Citations (Scopus)

  12 Downloads (Pure)
• 2019

  Metabonomics in gastroenterology and hepatology

  Bjerrum, J. T. & Nielsen, O. H., 1 Aug 2019, In: International Journal of Molecular Sciences. 20, 15, 3638.

  Research output: Contribution to journal › Editorial › Research › peer-review

  Open Access

  File
  8 Citations (Scopus)

  12 Downloads (Pure)
• 2018

  Characterization of the enhancer and promoter landscape of inflammatory bowel disease from human colon biopsies

  Boyd, M., Thodberg, M., Vitezic, M., Lange, J. B., Vitting-Seerup, K., Chen, Y., Coskun, M., Li, Y., Lo, B. Z. S., Klausen, P., Schweiger, P., Pedersen, A. G., Rapin, N. P. J-P., Skovgaard, K., Dahlgaard, K., Andersson, R., Terkelsen, T. B., Lilje, B., Troelsen, J. T., Petersen, A. M. & 7 others, Jensen, K. B., Gögenur, I., Thielsen, P., Seidelin, J. B., Nielsen, O. H., Bjerrum, J. T. & Sandelin, A. G., 2018, In: Nature Communications. 9, 19 p., 1661.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  67 Citations (Scopus)

  283 Downloads (Pure)

• Targeting JAK-STAT signal transduction in IBD

  Soendergaard, C., Bergenheim, F. H., Bjerrum, J. T. & Nielsen, O. H., 2018, In: Pharmacology & Therapeutics. 192, p. 100-111

  Research output: Contribution to journal › Journal article › Research › peer-review
  73 Citations (Scopus)
• 2016

  Non-infectious HIV-associated colitis as a differential diagnosis to ulcerative colitis

  Stefansdottir, J., Bjerrum, J. T. & Nielsen, S. D., 2016, In: Scandinavian Journal of Gastroenterology. 51, 8, p. 1017-1018 2 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
• 2015

  Integrative Transcriptomic and Metabonomic Molecular Profiling of Colonic Mucosal Biopsies Indicates a Unique Molecular Phenotype for Ulcerative Colitis

  Rantalainen, M., Bjerrum, J. T., Olsen, J., Nielsen, O. H. & Wang, Y., 2 Jan 2015, In: Journal of Proteome Research. 14, 1, p. 479-90 12 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  14 Citations (Scopus)

• Metabonomics of human fecal extracts characterize ulcerative colitis, Crohn's disease and healthy individuals

  Bjerrum, J. T., Wang, Y., Hao, F., Coskun, M., Ludwig, C., Guenther, U. & Nielsen, O. H., 2015, In: Metabolomics. 11, 1, p. 122-133 12 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access
  202 Citations (Scopus)
• 2014

  Assessment of the validity of a multigene analysis in the diagnostics of inflammatory bowel disease

  Bjerrum, J. T., Nyberg, C., Olsen, J. & Nielsen, O. H., May 2014, In: Journal of Internal Medicine. 275, 5, p. 484-93 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  21 Citations (Scopus)

• Identification of TNF-α-responsive promoters and enhancers in the intestinal epithelial cell model Caco-2

  Boyd, M., Coskun, M., Lilje, B., Andersson, R., Hoof, I., Lange, J. B., Dahlgaard, K., Olsen, J., Vitezic, M., Bjerrum, J. T., Seidelin, J. B., Nielsen, O. H., Troelsen, J. & Sandelin, A. G., 2014, In: D N A Research. 21, 6, p. 569-583 15 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  10 Citations (Scopus)

  1980 Downloads (Pure)

• Integration of transcriptomics and metabonomics: improving diagnostics, biomarker identification and phenotyping in ulcerative colitis

  Bjerrum, J. T., Rantalainen, M., Wang, Y., Olsen, J. & Nielsen, O. H., 2014, In: Metabolomics. 10, 2, p. 280-290 11 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  24 Citations (Scopus)

• Transcriptional analysis of left-sided colitis, pancolitis, and ulcerative colitis-associated dysplasia

  Bjerrum, J. T., Nielsen, O. H., Riis, L. B., Pittet, V., Mueller, C., Rogler, G. & Olsen, J., Dec 2014, In: Inflammatory Bowel Diseases. 20, 12, p. 2340-2352 13 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  29 Citations (Scopus)
• 2013

  Colitis ulcerosa

  Translated title of the contribution: Ulcerative colitisNielsen, O. H., Jess, T., Bjerrum, J. T. & Seidelin, J. B., 2013, In: Ugeskrift for Laeger. 175, 20, p. 1412-6 5 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  2 Citations (Scopus)

• miR-20b, miR-98, miR-125b-1*, and let-7e* as new potential diagnostic biomarkers in ulcerative colitis

  Coskun, M., Bjerrum, J. T., Seidelin, J. B., Troelsen, J., Olsen, J. & Nielsen, O. H., 21 Jul 2013, In: World Journal of Gastroenterology. 19, 27, p. 4289-99 11 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  80 Citations (Scopus)

• Noninfectious & noninflammatory bowel disease colitis

  Nielsen, O. H., Bjerrum, J. T. & Seidelin, J. B., 1 Mar 2013, Advances in the Management of Inflammatory Bowel Disease. Future Medicine Ltd., p. 33-49 17 p.

  Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

• Recent advances using immunomodulators for inflammatory bowel disease

  Nielsen, O. H., Bjerrum, J. T., Herfarth, H. & Rogler, G., 2013, In: British Journal of Clinical Pharmacology. Supplement. 53, 6, p. 575-588 14 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  40 Citations (Scopus)
• 2010

  Genome-wide Gene Expression Analysis of Mucosal Colonic Biopsies and Isolated Colonocytes Suggests a Continuous Inflammatory State in the Lamina Propria of Patients with Quiescent Ulcerative Colitis

  Bjerrum, J. T., Hansen, M., Olsen, J., Nielsen, O. H., Bjerrum, J. T., Hansen, M., Olsen, J. & Nielsen, O. H., 2010, In: Inflammatory Bowel Diseases. 16, 6, p. 999-1007 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  46 Citations (Scopus)

• IL-33 is upregulated in colonocytes of ulcerative colitis

  Seidelin, J. B., Bjerrum, J. T., Coskun, M., Widjaya, B., Vainer, B., Nielsen, O. H., Seidelin, J. B., Bjerrum, J. T., Coskun, M., Widjaya, B., Vainer, B. & Nielsen, O. H., 2010, In: Immunology Letters. 128, 1, p. 80-5 6 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  126 Citations (Scopus)

• Metabonomics in Ulcerative Colitis: Diagnostics, Biomarker Identification, And Insight into the Pathophysiology

  Bjerrum, J. T., Nielsen, O. H., Hao, F., Tang, H., Nicholson, J. K., Wang, Y., Olsen, J., Bjerrum, J. T., Nielsen, O. H., Shen, H., Tang, H. R., Nicholson, J. B., Wang, L. & Olsen, J., 2010, In: Journal of Proteome Research. 9, 2, p. 954-962 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  139 Citations (Scopus)

• Transcriptomics, metabonomics, and ulcerative colitis

  Bjerrum, J. T., 2010

  Research output: Book/Report › Ph.D. thesis › Research
• 2009

  Diagnosis of ulcerative colitis before onset of inflammation by multivariate modeling of genome-wide gene expression data

  Olsen, J., Gerds, T. A., Seidelin, J. B., Csillag, C., Bjerrum, J. T., Troelsen, J. T. & Nielsen, O. H., 2009, In: Inflammatory Bowel Diseases. 15, 7, p. 1032-8 6 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  74 Citations (Scopus)

• Influence of smoking on colonic gene expression profile in Crohn's disease

  Nielsen, O. H., Bjerrum, J. T., Csillag, C., Nielsen, F. C. & Olsen, J., 2009, In: PLoS ONE. 4, 7, p. e6210

  Research output: Contribution to journal › Journal article › Research › peer-review
  29 Citations (Scopus)
• 2008

  Technology insight: metabonomics in gastroenterology-basic principles and potential clinical applications.

  Bjerrum, J. T., Nielsen, O. H., Wang, Y. L. & Olsen, J., 2008, In: Nature Clinical Practice Gastroenterology & Hepatology. 5, 6, p. 332-43 11 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  24 Citations (Scopus)
• 2007

  Azathioprin og 6-mercaptopurin som vedligeholdelsesbehandling ved colitis ulcerosa: Gennemgang af Cochrane-review

  Bjerrum, J. E. & Nielsen, O. H., 12 Oct 2007, In: Ugeskrift for Laeger. 169, 50, p. 4341-4344 4 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

• CARD15 status and familial predisposition for Crohn's disease and colonic gene expression

  Csillag, C., Nielsen, O. H., Borup, R., Olsen, J., Bjerrum, J. T. & Nielsen, F. C., 2007, In: Digestive Diseases and Sciences. 52, 8, p. 1783-1789 6 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  10 Citations (Scopus)

• CARD15 status and familial predisposition for Crohn's disease and colonic gene expression

  Csillag, C., Nielsen, O. H., Borup, R., Olsen, J., Bjerrum, J. T. & Nielsen, F. C., 2007, In: Digestive Diseases and Sciences. 52, 8, p. 1783-1789

  Research output: Contribution to journal › Journal article › Research › peer-review
  10 Citations (Scopus)

• TNF-α-antistofbehandling og remissionsinduktion ved colitis ulcerosa: Gennemgang af et Cochrane-review

  Bjerrum, J. T., Munck, L. K., Krogh-Madsen, M. & Nielsen, O. H., 26 Feb 2007, In: Ugeskrift for Laeger. 169, 9, p. 792-795 4 p.

  Research output: Contribution to journal › Review › Research › peer-review

  1 Citation (Scopus)
• 2006

  Perioperativ blodtransfusion og recidiv af karcinom i colon og rectum: Gennemgang af et Cochrane-review

  Bjerrum, J. T., Jensen, L. S. & Nielsen, O. H., 21 Aug 2006, In: Ugeskrift for Laeger. 168, 34, 1 p.

  Research output: Contribution to journal › Review › Research › peer-review

  3 Citations (Scopus)