Jakob Schmidt Jespersen

Search results

• 2024

  Clonal hematopoiesis and COVID-19 hospitalization in Danish adults

  Burgos Sequeros, C., Tulstrup, M., Bliddal, S., Sørensen, K. M., Nissen, I., Rezahosseini, O., Brooks, P. T., Feenstra, B., Gang, A. O., Geller, F., Hald, A., Harboe, Z. B., Helleberg, M., Jespersen, J. S., Lebech, A. M., Lindegaard, B., Mogensen, T. H., Møller, M. E. E., Nielsen, C. H., Niemann, C. U. & 13 others, Podlekareva, D., Sejdic, A., Sørensen, E., Teglgaard, R. S., Tommerup, N., Weis, N., Brunak, S., Pedersen, O. B. V., Banasik, K., Feldt-Rasmussen, U., Nielsen, S. D., Ostrowski, S. R. & Grønbæk, K., 2024, In: HemaSphere. 8, 3, 5 p., e58.

  Research output: Contribution to journal › Letter › Research › peer-review

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• Epigenetic regulators of clonal hematopoiesis control CD8 T cell stemness during immunotherapy

  Kang, T. G., Lan, X., Mi, T., Chen, H., Alli, S., Lim, S. E., Bhatara, S., Vasandan, A. B., Ward, G., Bentivegna, S., Jang, J., Spatz, M. L., Han, J. H., Schlotmann, B. C., Jespersen, J. S., Derenzo, C., Vogel, P., Yu, J., Baylin, S., Jones, P. & 4 others, O'Connell, C., Grønbæk, K., Youngblood, B. & Zebley, C. C., 2024, In: Science (New York, N.Y.). 386, 6718, 15 p., eadl4492.

  Research output: Contribution to journal › Journal article › Research › peer-review
  1 Citation (Scopus)
• 2023

  Frequency and Functional Characterization of RUNX1 Germline Variants in Myeloid Neoplasms

  Nitschke, N. J., Almosailleakh, M., Niu, Y., Hansen, J. W., Raaschou-Jensen, K., Jespersen, J. S., Severinsen, M. T., Roug, A. S., Frödin, M., Weischenfeldt, J. L., Andersen, M. K. & Grønbæk, K., 2023, In: Human Mutation. 2023, 11 p., 4738660.

  Research output: Contribution to journal › Journal article › Research › peer-review

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• Impact of U2AF1 mutations on circular RNA expression in myelodysplastic neoplasms

  Wedge, E., Ahmadov, U., Hansen, T. B., Gao, Z., Tulstrup, M., Côme, C., Nonavinkere Srivatsan, S., Ahmed, T., Jespersen, J. S., Schlotmann, B. C., Schöllkopf, C., Raaschou-Jensen, K., Ødum, N., Kjems, J., Bak, R. O., Walter, M. J., Grønbæk, K. & Kristensen, L. S., 2023, In: Leukemia. 37, p. 1113-1125

  Research output: Contribution to journal › Journal article › Research › peer-review
  6 Citations (Scopus)

• Overall Survival in Patients with Ccus Depends on Presence of Anemia

  Træden, D., Tulstrup, M., Johansen, M. M., Ørskov, A. D., Marcher, C., Raaschou-jensen, K., Stidsholt Roug, A., Severinsen, M. T., Porse, B., Theilgaard-mönch, K., Jespersen, J., Cowland, J. B., Sjö, L., Andersen, M. K., Grønbæk, K. & Hansen, J. W., 2023, In: Blood. 142, Suppl. 1, p. 1864-1865

  Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  Open Access
• 2022

  Clonal hematopoiesis is associated with hematological toxicity during lenalidomide-based therapy for MCL

  Husby, S., Bæch-Laursen, C., Eskelund, C. W., Favero, F., Jespersen, J. S., Hutchings, M., Pedersen, L. B., Niemann, C. U., Weischenfeldt, J., Räty, R., Larsen, T. S., Kolstad, A., Jerkeman, M. & Grønbæk, K., 2022, In: Leukemia. 36, p. 2912-2916

  Research output: Contribution to journal › Journal article › Research › peer-review
  3 Citations (Scopus)

• Level of unique T cell clonotypes is associated with clonal hematopoiesis and survival in patients with lymphoma undergoing ASCT

  Husby, S., Jørgensen, G. Ø., Favero, F., Jespersen, J. S., Rodriguez-Gonzalez, F. G., Nielsen, C., Sorensen, B., Ebbesen, L. H., Bæch, J., Haastrup, E. K., Josefsson, P., Thorsgaard, M., Brown, P., El-Galaly, T. C., Larsen, T. S., Weischenfeldt, J. & Grønbæk, K., 2022, In: Bone Marrow Transplantation. 57, p. 674-677

  Research output: Contribution to journal › Letter › Research › peer-review
  2 Citations (Scopus)
• 2019

  Cerebral malaria is associated with differential cytoadherence to brain endothelial cells

  Storm, J., Jespersen, J. S., Seydel, K. B., Szestak, T., Mbewe, M., Chisala, N. V., Phula, P., Wang, C. W., Taylor, T. E., Moxon, C. A., Lavstsen, T. & Craig, A. G., 2019, In: EMBO Molecular Medicine. 2019, 11, 15 p., e9164.

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  77 Citations (Scopus)

  132 Downloads (Pure)
• 2018

  Antibodies to intercellular adhesion molecule 1-binding Plasmodium falciparum erythrocyte membrane protein 1-DBLβ are biomarkers of protective immunity to malaria in a cohort of young children from Papua New Guinea

  Tessema, S. K., Utama, D., Chesnokov, O., Hodder, A. N., Lin, C. S., Harrison, G. L. A., Jespersen, J. S., Petersen, B., Tavul, L., Siba, P., Kwiatkowski, D., Lavstsen, T., Hansen, D. S., Oleinikov, A. V., Mueller, I. & Barry, A. E., 1 Aug 2018, In: Infection and Immunity. 86, 8, p. 1-14 14 p., e00485-17.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access
  16 Citations (Scopus)
• 2017

  Cellulose filtration of blood from malaria patients for improving ex vivo growth of Plasmodium falciparum parasites

  Mkumbaye, S. I., Minja, D. T. R., Jespersen, J. S., Alifrangis, M., Kavishe, R. A., Mwakalinga, S. B., Lusingu, J. P., Theander, T. G., Lavstsen, T. & Wang, C. W., 10 Feb 2017, In: Malaria Journal. 16, 1, 8 p., 69.

  Research output: Contribution to journal › Journal article › Research › peer-review

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  5 Citations (Scopus)

  254 Downloads (Pure)

• Parasites causing cerebral falciparum malaria bind multiple endothelial receptors and express EPCR and ICAM-1-binding PfEMP1

  Tuikue Ndam, N., Moussiliou, A., Lavstsen, T., Kamaliddin, C., Jensen, A. T. R., Mama, A., Tahar, R., Wang, C. W., Jespersen, J. S., Alao, J. M., Gamain, B., Theander, T. G. & Deloron, P., 2017, In: The Journal of Infectious Diseases. 215, 12, p. 1918-1925 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  59 Citations (Scopus)

• Plasmodium falciparum causing febrile infections express EPCR- binding PfEMP1

  Mkumbaye, S., Wang, C. W., Jespersen, J. S., Petersen, J. E. V., Kavishe, R., Lusingu, J., Theander, T. G. & Lavstsen, T., Oct 2017, In: Tropical Medicine & International Health. 22, S1, p. 7-7 1S3.3.

  Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

• Structure-guided identification of a family of dual receptor-binding PfEMP1 that is associated with cerebral malaria

  Lennartz, F., Adams, Y., Bengtsson, A., Olsen, R. W., Turner, L., Ndam, N. T., Ecklu-Mensah, G. D., Moussiliou, A., Ofori, M. F., Gamain, B., Lusingu, J. P., Petersen, J. E. V., Wang, C. W., Nunes-Silva, S., Jespersen, J. S., Lau, C. K. Y., Theander, T. G., Lavstsen, T., Hviid, L., Higgins, M. K. & 1 others, Jensen, A. T. R., 8 Mar 2017, In: Cell Host & Microbe. 21, 3, p. 403-414 12 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

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  137 Citations (Scopus)

  701 Downloads (Pure)

• The Severity of Plasmodium falciparum infection is associated with transcript levels of var genes encoding endothelial protein C receptor-binding P. falciparum erythrocyte membrane protein 1

  Mkumbaye, S. I., Wang, C. W., Lyimo, E., Jespersen, J. S., Manjurano, A., Mosha, J., Kavishe, R. A., Mwakalinga, S. B., Minja, D. T. R., Lusingu, J. P., Theander, T. G. & Lavstsen, T., 2017, In: Infection and Immunity. 85, 4, 14 p., 4e00841-16.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access
  57 Citations (Scopus)
• 2016

  Plasmodium falciparum var genes expressed in children with severe malaria encode CIDRα1 domains

  Jespersen, J. S., Wang, C. W., Mkumbaye, S. I., Minja, D. T., Petersen, B., Turner, L., Petersen, J. E., Lusingu, J. P., Theander, T. G. & Lavstsen, T., 2016, In: EMBO Molecular Medicine. 8, 8, p. 839-850 12 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

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  71 Citations (Scopus)

  328 Downloads (Pure)
• 2015

  Identification of a Major Dimorphic Region in the Functionally Critical N-Terminal ID1 Domain of VAR2CSA

  Doritchamou, J., Sabbagh, A., Jespersen, J. S., Renard, E., Salanti, A., Nielsen, M. A., Deloron, P. & Tuikue Ndam, N., 2015, In: PLOS ONE. 10, 9, 14 p., e0137695.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access
  19 Citations (Scopus)

• Structural Conservation Despite Huge Sequence Diversity Allows EPCR Binding by the PfEMP1 Family Implicated in Severe Childhood Malaria

  Lau, C. K. Y., Turner, L., Jespersen, J. S., Lowe, E. D., Petersen, B., Wang, C. W., Petersen, J. E. V., Lusingu, J., Theander, T. G., Lavstsen, T. & Higgins, M. K., 14 Jan 2015, In: Cell Host & Microbe. 17, 1, p. 118-29 12 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access
  138 Citations (Scopus)
• 2014

  DNA secondary structures are associated with recombination in major Plasmodium falciparum variable surface antigen gene families

  Pedersen, A. F. S., Lavstsen, T., Rask, T. S., Lisby, M., Salanti, A., Fordyce, S. L., Jespersen, J. S., Carter, R., Deitsch, K. W., Theander, T. G., Pedersen, A. G. & Arnot, D. E., 2014, In: Nucleic Acids Research. 42, 4, p. 2270-81 12 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  34 Citations (Scopus)
• 2013

  Expression of the domain cassette 8 Plasmodium falciparum erythrocyte membrane protein 1 is associated with cerebral malaria in Benin

  Bertin, G. I., Lavstsen, T., Guillonneau, F., Doritchamou, J., Wang, C. W., Jespersen, J. S., Ezimegnon, S., Fievet, N., Alao, M. J., Lalya, F., Massougbodji, A., Ndam, N. T., Theander, T. G. & Deloron, P., 2013, In: P L o S One. 8, 7, p. e68368

  Research output: Contribution to journal › Journal article › Research › peer-review
  53 Citations (Scopus)

• Severe malaria is associated with parasite binding to endothelial protein C receptor

  Turner, L., Lavstsen, T., Berger, S. S., Wang, C. W., Petersen, J. E. V., Avril, M., Brazier, A. J., Freeth, J., Jespersen, J. S., Nielsen, M. A., Magistrado, P., Lusingu, J., Smith, J. D., Higgins, M. K. & Theander, T. G., 27 Jun 2013, In: Nature. 498, 7455, p. 502-5 4 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  422 Citations (Scopus)
• 2012

  Plasmodium falciparum erythrocyte membrane protein 1 domain cassettes 8 and 13 are associated with severe malaria in children

  Lavstsen, T., Turner, L., Saguti, F., Magistrado, P. A., Rask, T. S., Jespersen, J. S., Wang, C. W., Berger, S. S., Baraka, V., Marquard, A. M., Seguin-Orlando, A., Willerslev, E., Gilbert, T., Lusingu, J. P. A. & Theander, T. G., 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 26, p. E1791-E1800 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  204 Citations (Scopus)