Jan Benada

Search results

• 2023

  Self-inflicted DNA breaks in cell differentiation and cancer

  Benada, J., Alsowaida, D., Megeney, L. A. & Sørensen, C. S., 2023, In: Trends in Cell Biology. 33, 10, p. 850-859

  Research output: Contribution to journal › Journal article › Research › peer-review
  4 Citations (Scopus)

• Synthetic lethal interaction between WEE1 and PKMYT1 is a target for multiple low-dose treatment of high-grade serous ovarian carcinoma

  Benada, J., Bulanova, D., Azzoni, V., Petrosius, V., Ghazanfar, S., Wennerberg, K. & Sørensen, C. S., 2023, In: NAR Cancer. 5, 3, 13 p., zcad029.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  9 Citations (Scopus)

  27 Downloads (Pure)

• Temporal phosphoproteomics reveals WEE1-dependent control of 53BP1 pathway

  Petrosius, V., Benada, J., Nielsen, O., Schoof, E. M. & Sørensen, C. S., 2023, In: iScience. 26, 1, 24 p., 105806.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  4 Citations (Scopus)

  20 Downloads (Pure)
• 2022

  A catalog of curated breast cancer genes

  Bose, M., Benada, J., Thatte, J. V., Kinalis, S., Ejlertsen, B., Nielsen, F. C., Sørensen, C. S. & Rossing, M., 2022, In: Breast Cancer Research and Treatment. 191, p. 431-441

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  5 Citations (Scopus)

  30 Downloads (Pure)

• Cancer cells use self-inflicted DNA breaks to evade growth limits imposed by genotoxic stress

  Larsen, B. D., Benada, J., Yung, P. Y. K., Bell, R. A. V., Pappas, G., Urban, V., Ahlskog, J. K., Kuo, T. T., Janscak, P., Megeney, L. A., Elsässer, S. J., Bartek, J. & Sørensen, C. S., 2022, In: Science. 376, 6592, p. 476-483 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  36 Citations (Scopus)

• The TRESLIN-MTBP complex couples completion of DNA replication with S/G2 transition

  Zonderland, G., Vanzo, R., Amitash, S., Martín-Doncel, E., Coscia, F., Mund, A., Lerdrup, M., Benada, J., Boos, D. & Toledo, L., 2022, In: Molecular Cell. 82, 18, p. 3350-3365.e7 24 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  9 Citations (Scopus)

  25 Downloads (Pure)

• WEE1 kinase protects the stability of stalled DNA replication forks by limiting CDK2 activity

  Elbæk, C. R., Petrosius, V., Benada, J., Erichsen, L., Damgaard, R. B. & Sørensen, C. S., 2022, In: Cell Reports. 38, 3, 110261.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  31 Citations (Scopus)

  29 Downloads (Pure)
• 2020

  Physiological Tolerance to ssDNA Enables Strand Uncoupling during DNA Replication

  Ercilla, A., Benada, J., Amitash, S., Zonderland, G., Baldi, G., Somyajit, K., Ochs, F., Costanzo, V., Lukas, J. & Toledo, L., 2020, In: Cell Reports. 30, 7, p. 2416-2429.e7 22 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  44 Citations (Scopus)

  176 Downloads (Pure)
• 2019

  Overcoming Treatment Toxicity through Sequential Therapy

  Benada, J., Ejlertsen, B. & Sørensen, C. S., 2019, In: Cancer Cell. 35, 6, p. 821-822 2 p.

  Research output: Contribution to journal › Journal article › Research
  3 Citations (Scopus)