Jan Christiansen

2021

Unveiling mRNP composition by fluorescence correlation and cross-correlation spectroscopy using cell lysates

Mateu-Regué, À., Christiansen, J., Bagger, F. O., Hellriegel, C. & Nielsen, F. C., 2021, In: Nucleic Acids Research. 49, 20, 15 p., e119.

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6 Citations (Scopus)

17 Downloads (Pure)

2020

Cytoplasmic mRNPs revisited: Singletons and condensates

Mateu-Regue, A., Nielsen, F. C. & Christiansen, J., 2020, In: BioEssays. 42, 12, 13 p., 2000097.

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4 Citations (Scopus)

38 Downloads (Pure)

2019

Single mRNP Analysis Reveals that Small Cytoplasmic mRNP Granules Represent mRNA Singletons

Mateu-Regué, À., Christiansen, J., Bagger, F. O., Winther, O., Hellriegel, C. & Nielsen, F. C., 2019, In: Cell Reports. 29, 3, p. 736-748, e1-e4

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18 Citations (Scopus)

92 Downloads (Pure)

2016

Oncogenic p95HER2 regulates Na⁺-HCO₃^- cotransporter NBCn1 mRNA stability in breast cancer cells via 3'UTR-dependent processes

Gorbatenko, A., Olesen, C. W., Loebl, N., Sigurdsson, H. H., Bianchi, C., Pedraz Cuesta, E., Christiansen, J. & Pedersen, S. H. F., 2016, In: Biochemical Journal. 473, 21, p. 4027-4044 18 p.

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15 Citations (Scopus)

RNA assemblages orchestrate complex cellular processes

Nielsen, F. C., Hansen, H. T. & Christiansen, J., 2016, In: BioEssays. 38, 7, p. 674-681 8 p.

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20 Citations (Scopus)

291 Downloads (Pure)

2015

Drosophila Imp iCLIP identifies an RNA assemblage coordinating F-actin formation

Hansen, H. T., Rasmussen, S. H., Adolph, S. K., Plass, M., Krogh, A., Sanford, J., Nielsen, F. C. & Christiansen, J., 2015, In: Genome Biology (Online Edition). 16, 16 p., 123.

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24 Citations (Scopus)

484 Downloads (Pure)

2014

IMP3 RNP safe houses prevent miRNA-directed HMGA2 mRNA decay in cancer and development

Jønson, L., Christiansen, J., Hansen, T. V. O., Vikeså, J., Yamamoto, Y. & Nielsen, F. C., 2014, In: Cell Reports. 7, 2, p. 539-551 13 p.

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75 Citations (Scopus)

1610 Downloads (Pure)

2013

mTOR complex 2 phosphorylates IMP1 cotranslationally to promote IGF2 production and the proliferation of mouse embryonic fibroblasts.

Dai, N., Christiansen, J., Nielsen, F. & Avruch, J., 2013, In: Genes & Development. 27, 3, p. 301-312 12 p.

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73 Citations (Scopus)

2009

CRISPR families of the crenarchaeal genus Sulfolobus: bidirectional transcription and dynamic properties

Lillestøl, R. K., Shah, S. A., Brügger, K., Redder, P., Phan, H., Christiansen, J. & Garrett, R. A., 2009, In: Molecular Microbiology. 72, 1, p. 259-272

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196 Citations (Scopus)

2008

Embryonic expression of Drosophila IMP in the developing CNS and PNS

Adolph, S. K., Delotto, R., Nielsen, F. C. & Christiansen, J., 2008, In: Gene Expression Patterns. 9, 3, p. 138-143 5 p.

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10 Citations (Scopus)

2007

Molecular composition of IMP1 ribonucleoprotein granules.

Jønson, L., Vikesaa, J., Krogh, A., Nielsen, L. K., Hansen, T. VO., Borup, R., Johnsen, A. H., Christiansen, J. & Nielsen, F. C., 2007, In: Molecular and Cellular Proteomics. 6, 5, p. 798-811 13 p.

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181 Citations (Scopus)

2006

RNA-binding IMPs promote cell adhesion and invadopodia formation.

Vikesaa, J., Hansen, T. V. O., Jønson, L., Borup, R., Wewer, U. M., Christiansen, J. & Nielsen, F. C., 2006, In: EMBO Journal. 25, 7, p. 1456-68 12 p.

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283 Citations (Scopus)

2005

Expression of IGF-II mRNA-binding proteins (IMPs) in gonads and testicular cancer

Hammer, N. A., Hansen, T. V. O., Byskov, A. G., Rajpert-De Meyts, E., Grøndahl, M. L., Bredkjaer, H. E., Wewer, U. M., Christiansen, J. & Nielsen, F. C., 2005, In: Reproduction. 130, 2, p. 203-12 10 p.

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125 Citations (Scopus)

2004

Dwarfism and impaired gut development in insulin-like growth factor II mRNA-binding protein 1-deficient mice

Hansen, T. V. O., Hammer, N. A., Nielsen, J., Madsen, M., Dalbaeck, C., Wewer, U. M., Christiansen, J. & Nielsen, F. C., 2004, In: Molecular and Cellular Biology. 24, 10, p. 4448-64 17 p.

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196 Citations (Scopus)

Sequential dimerization of human zipcode-binding protein IMP1 on RNA: a cooperative mechanism providing RNP stability

Nielsen, J., Kristensen, M. A., Willemoes, M., Nielsen, F. C. & Christiansen, J., 2004, In: Nucleic Acids Research. 32, 14, p. 4368-4376

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103 Citations (Scopus)

2003

Nuclear transit of human zipcode-binding protein IMP1

Nielsen, J., Adolph, SK., Rajpert-De Meyts, E., Lykke-Andersen, J., Koch, G., Christiansen, J. & Nielsen, FC., 2003, In: Biochemical Journal. vol 376, p. 383-391

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46 Citations (Scopus)

2002

Cytoplasmic trafficking of IGF-II mRNA-binding rotein by conserved KH domains

Nielsen, F. C., Nielsen, J., Koch, G. & Christiansen, J., 2002, In: Journal of Cell Science. 115, p. 2087-2097

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Human insulin-like growth factor II leader 2 mediates internal initiation of translation

Pedersen, S., Christiansen, J., Hansen, T. O., Larsen, M. & Nielsen, F. C., 2002, In: Biochem. J.. 363, p. 37-44

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27 Citations (Scopus)

Human insulin-like growth II leader 2 mediates internal initiation of translation

Pedersen, S., Christiansen, J., Hansen, T., Larsen, M. & Nielsen, F., 2002, In: Biochem. J.. 363, p. 37-44

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2001

Aberrant expression of fetal RNA-binding protein p62 in liver cancer and liver cirrhosis

Lu, M., Nakamura, R. M., Dent, E. D., Zhang, J-Y., Nielsen, F. C., Christiansen, J., Chan, E. K. L. & Tan, E. M., 2001, In: American Journal of Pathology. 159, p. 945-953

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95 Citations (Scopus)

c-myc and IGF-II mRNA-binding protein (CRD-BP/IMP-1) in benign and malignant mesenchymal tumors

Ioanidis, P., Trangas, T., Dimitriadis, E., Samiotaki, M., Kyriazoglou, I., Tsiapalis, C. M., Kittas, C., Agnantis, N., Nielsen, F. C., Nielsen, J., Christiansen, J. & Pandis, N., 2001, In: International Journal of Cancer. 94, p. 480-484

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2000

H19 RNA binds four molecules of insulin-like growth factor II mRNA-binding protein

Runge, S., Nielsen, F. C., Nielsen, J., Andersen, J. L., Wewer, U. M. & Christiansen, J., 2000, In: Journal of Biological Chemistry. 275, 38, p. 29562-9 8 p.

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145 Citations (Scopus)

The biphasic expression of IMP/Vg1-RBP is conserved between vertebrates and Drosophila

Nielsen, J., Nielsen, F. C., Jakobsen, R. K. & Christiansen, J., 2000, In: Mechanisms of Development. 96, p. 129-132

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1999

A family of insulin-like growth factor II mRNA-binding proteins represses translation in late development

Nielsen, J., Christiansen, J., Lykke-Andersen, J., Johnsen, A. H., Wewer, U. M. & Nielsen, F. C., 1999, In: Molecular and Cellular Biology. 19, 2, p. 1262-1270 9 p.

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601 Citations (Scopus)

1998

The C-terminal carboxy group of T7 RNA polymerase ensures efficient magnesium ion-dependent catalysis

Lykke-Andersen, J. & Christiansen, J., 1998, In: Nucleic Acids Research. Vol. 26, no. 24, p. 5630-5635

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27 Citations (Scopus)

1997

Distinct repression of translation by wortmannin and rapamycin

Pedersen, S., Celis, J. E., Nielsen, J., Christiansen, J. & Nielsen, F. C., 1997, In: European Journal of Biochemistry. 247, p. 449-456

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41 Citations (Scopus)

1995

Growth-dependent translation of IGF-II mRNA by a rapamycin-sensitive pathway

Nielsen, F. C., Østergaard, L., Nielsen, J. & Christiansen, J., 1995, In: Nature. Vol 377, p. 358-362

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159 Citations (Scopus)

1994

A guanosine quadruplex and two stable hairpins flank a major cleavage site in insulin-like growth factor II mRNA

Christiansen, J., Kofod, M. & Nielsen, F. C., 1994, In: Nucleic Acids Research. 22, 25, p. 5709-16 7 p.

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77 Citations (Scopus)

Insulin-like growth factor II mRNA, peptides, and receptors in a thoracopulmonary malignant small round cell tumor

Nielsen, F. C., Orskov, C., Haselbacher, G., Ramlau, J., Christiansen, J., Schmiegelow, K. & Rehfeld, J. F., 1994, In: Cancer. 73, 4, p. 1312-9 7 p.

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9 Citations (Scopus)

1993

Biosynthesis of 10 kDa and 7.5 kDa insulin-like growth factor II in a human rhabdomyosarcoma cell line

Nielsen, F. C., Haselbacher, G., Christiansen, J., Lake, M., Gammeltoft, S. & Grønborg, M., 1993, In: Molecular and Cellular Endocrinology. 93, 1, p. 87-95 8 p.

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27 Citations (Scopus)

1992

Endonucleolysis in the turnover of insulin-like growth factor II mRNA

Nielsen, F. C. & Christiansen, J., 1992, In: Journal of Biological Chemistry. 267, 27, p. 19404-11 7 p.

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60 Citations (Scopus)

1991

Attachment sites of primary binding proteins L1, L2 and L23 on 23 S ribosomal RNA of Escherichia coli

Egebjerg, J., Christiansen, J. & Garrett, R. A., 1991, In: Journal of Molecular Biology. 222, 2, p. 251-264

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43 Citations (Scopus)

Insulin-like growth factor II: complexity of biosynthesis and receptor binding

Gammeltoft, S., Christiansen, J., Nielsen, F. C. & Verland, S., 1991, In: Advances in Experimental Medicine and Biology. 293, p. 31-44 13 p.

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10 Citations (Scopus)

Jan Christiansen

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