Jens Frey Halling

Research output

Research output per year 2016 2018 2020 2023

• 763 Citations
• 14 Journal article
• 1 Ph.D. thesis
• 1 Review

Research output per year

Research output per year

Search results

• 2023

  Impact of Aging and Lifelong Exercise Training on Mitochondrial Function and Network Connectivity in Human Skeletal Muscle

  Ringholm, S., Gudiksen, A., Halling, J. F., Qoqaj, A., Rasmussen, P. M., Prats, C., Plomgaard, P. & Pilegaard, H., 2023, In: Journals of Gerontology. Series A: Biological Sciences & Medical Sciences. 78, 3, 11 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  File
  14 Citations (Scopus)

• Muscle PGC-1α modulates hepatic mitophagy regulation during aging

  Christensen, N. M., Ringholm, S., Buch, B. T., Gudiksen, A., Halling, J. F. & Pilegaard, H., 2023, In: Experimental Gerontology. 172, 9 p., 112046.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  4 Citations (Scopus)

  18 Downloads (Pure)
• 2022

  Skeletal muscle adaptations to exercise are not influenced by metformin treatment in humans: secondary analyses of 2 randomised, clinical trials

  Pilmark, N. S., Oberholzer, L., Halling, J. F., Kristensen, J. M., Bønding, C. P., Elkjær, I., Lyngbæk, M., Elster, G., Siebenmann, C., Holm, N. F., Birk, J. B., Larsen, E. L., Meinild-Lundby, A-K., Wojtaszewski, J., Pilegaard, H., Poulsen, H., Pedersen, B. K., Hansen, K. B. & Karstoft, K., 2022, In: Applied Physiology, Nutrition and Metabolism. 47, 3, p. 309-320 12 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  8 Citations (Scopus)

  63 Downloads (Pure)
• 2020

  Colchicine treatment impairs skeletal muscle mitochondrial function and insulin sensitivity in an age-specific manner

  Buch, B. T., Halling, J. F., Ringholm, S., Gudiksen, A., Kjøbsted, R., Olsen, M. A., Wojtaszewski, J. & Pilegaard, H., 2020, In: F A S E B Journal. 34, 6, p. 8653-8670

  Research output: Contribution to journal › Journal article › Research › peer-review
  15 Citations (Scopus)

• Inducible deletion of skeletal muscle AMPKα 1 reveals that AMPK is required for nucleotide balance but dispensable for muscle glucose uptake and fat oxidation during exercise

  Hingst, J. R., Kjøbsted, R., Birk, J. B., Jørgensen, N. O., Larsen, M. R., Kido, K., Larsen, J. K., Kjeldsen, S. A. S., Fentz, J., Frøsig, C., Holm, S., Fritzen, A. M., Dohlmann, T. L., Larsen, S., Foretz, M., Viollet, B., Schjerling, P., Overby, P., Halling, J. F., Pilegaard, H. & 2 others, Hellsten, Y. & Wojtaszewski, J., 2020, In: Molecular Metabolism. 40, 17 p., 101028.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  32 Citations (Scopus)

  184 Downloads (Pure)

• PGC-1α-mediated regulation of mitochondrial function and physiological implications

  Halling, J. F. & Pilegaard, H., 2020, In: Applied Physiology, Nutrition and Metabolism. 45, 9, p. 927-936 10 p.

  Research output: Contribution to journal › Review › Research › peer-review
  142 Citations (Scopus)
• 2019

  Lifelong physical activity is associated with promoter hypomethylation of genes involved in metabolism, myogenesis, contractile properties and oxidative stress resistance in aged human skeletal muscle

  Sailani, M. R., Halling, J. F., Møller, H. D., Lee, H., Plomgaard, P., Pilegaard, H., Snyder, M. P. & Regenberg, B., 2019, In: Scientific Reports. 9, p. 1-11 3272.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  70 Citations (Scopus)

  162 Downloads (Pure)

• PGC-1α regulates mitochondrial properties beyond biogenesis with aging and exercise training

  Halling, J. F., Jessen, H., Nøhr-Meldgaard, J., Buch, B. T., Christensen, N. M., Gudiksen, A., Ringholm, S., Neufer, P. D., Prats, C. & Pilegaard, H., 2019, In: American journal of physiology. Endocrinology and metabolism. 317, 3, p. E513-E525

  Research output: Contribution to journal › Journal article › Research › peer-review
  47 Citations (Scopus)
• 2018

  Circular DNA elements of chromosomal origin are common in healthy human somatic tissue

  Møller, H. D., Mohiyuddin, M., Prada Luengo, I., Sailani, M. R., Halling, J. F., Plomgaard, P., Maretty, L., Hansen, A. J., Snyder, M. P., Pilegaard, H., Lam, H. Y. K. & Regenberg, B., 1 Dec 2018, In: Nature Communications. 9, 12 p., 1069.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  200 Citations (Scopus)

  349 Downloads (Pure)

• Oxygen conserving mitochondrial adaptations in the skeletal muscles of breath hold divers

  Kjeld, T., Stride, N., Gudiksen, A., Hansen, E. G., Arendrup, H. C., Horstmann, P. F., Zerahn, B., Jensen, L. T., Nordsborg, N. B., Bejder, J. & Halling, J. F., 19 Sep 2018, In: P L o S One. 13, 9, p. 1-13 13 p., e0201401.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  19 Citations (Scopus)

  224 Downloads (Pure)

• Regulation of apoptosis and autophagy in mouse and human skeletal muscle with aging and lifelong exercise training

  Dethlefsen, M. M., Halling, J. F., Møller, H. D., Plomgaard, P., Regenberg, B., Ringholm, S. & Pilegaard, H., 2018, In: Experimental Gerontology. 111, p. 141-153

  Research output: Contribution to journal › Journal article › Research › peer-review
  42 Citations (Scopus)

• The impact of exercise training and resveratrol supplementation on gut microbiota composition in high-fat diet fed mice

  Brandt, N., Kotowska, D., Kristensen, C. M., Olesen, J., Lützhøft, D. O., Halling, J. F., Hansen, M., Al-Soud, W. A., Hansen, L., Kiilerich, P. & Pilegaard, H., 2018, In: Physiological Reports. 6, 20, p. 1-11 e13881.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  25 Citations (Scopus)

  190 Downloads (Pure)

• Why PGC-1α matters: Regulation of skeletal muscle mitochondrial function beyond biogenesis

  Halling, J. F., 2018, Department of Biology, Faculty of Science, University of Copenhagen.

  Research output: Book/Report › Ph.D. thesis

  File
• 2017

  Autophagy-dependent beneficial effects of exercise

  Halling, J. F. & Pilegaard, H., Aug 2017, In: Cold Spring Harbor Perspectives in Medicine. 7, 8, a029777.

  Research output: Contribution to journal › Journal article › Research › peer-review
  36 Citations (Scopus)

• Exercise training protects against aging-induced mitochondrial fragmentation in mouse skeletal muscle in a PGC-1α dependent manner

  Halling, J. F., Jørgensen, S. R., Olesen, J., Prats Gavalda, C. & Pilegaard, H., 1 Oct 2017, In: Experimental Gerontology. 96, p. 1-6 6 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  65 Citations (Scopus)
• 2016

  PGC-1α promotes exercise-induced autophagy in mouse skeletal muscle

  Halling, J. F., Jørgensen, S. R., Nielsen, M. M., Overby, P. & Pilegaard, H., 2016, In: Physiological Reports. 4, 3, 11 p., e12698.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  44 Citations (Scopus)

  380 Downloads (Pure)