Jens Vilstrup Johansen

Search results

• 2024

  Influence of vitamin D receptor signalling and vitamin D on colonic epithelial cell fate decisions in ulcerative colitis

  Kellermann, L., Hansen, S. L., Maciag, G., Granau, A. M., Johansen, J. V., Teves, J. M., Bressan, R. B., Pedersen, M. T., Soendergaard, C., Baattrup, A. M., Hammerhøj, A., Riis, L. B., Gubatan, J., Jensen, K. B. & Nielsen, O. H., 2024, In: Journal of Crohn's & colitis. 18, 10, p. 1672–1689 18 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  2 Citations (Scopus)

  3 Downloads (Pure)
• 2023

  An alternative NURF complex sustains acute myeloid leukemia by regulating the accessibility of insulator regions

  Radzisheuskaya, A., Peña-Rømer, I., Lorenzini, E., Koche, R., Zhan, Y., Shliaha, P. V., Cooper, A. J., Fan, Z., Shlyueva, D., Johansen, J. V., Hendrickson, R. C. & Helin, K., 2023, In: EMBO Journal. 42, 24, 22 p., e114221.

  Research output: Contribution to journal › Journal article › peer-review

  Open Access

  File
  4 Citations (Scopus)

  5 Downloads (Pure)

• An organoid-based CRISPR-Cas9 screen for regulators of intestinal epithelial maturation and cell fate

  Hansen, S. L., Larsen, H. L., Pikkupeura, L. M., Maciag, G., Guiu, J., Müller, I., Clement, D. L., Mueller, C., Johansen, J. V., Helin, K., Lerdrup, M. & Jensen, K. B., 2023, In: Science Advances. 9, 28, 18 p., eadg4055.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  17 Citations (Scopus)

  58 Downloads (Pure)
• 2021

  Acute Experimental Barrier Injury Triggers Ulcerative Colitis–Specific Innate Hyperresponsiveness and Ulcerative Colitis–Type Microbiome Changes in Humans

  Seidelin, J. B., Bahl, M. I., Licht, T. R., Mead, B. E., Karp, J. M., Johansen, J. V., Riis, L. B., Galera, M. R., Woetmann, A. & Bjerrum, J. T., 2021, In: Cellular and Molecular Gastroenterology and Hepatology. 12, 4, p. 1281-1296

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  9 Citations (Scopus)

  18 Downloads (Pure)

• Effects of a single dose of psilocybin on behaviour, brain 5-HT_2A receptor occupancy and gene expression in the pig

  Donovan, L. L., Johansen, J. V., Ros, N. F., Jaberi, E., Linnet, K., Johansen, S. S., Ozenne, B., Issazadeh-Navikas, S., Hansen, H. D. & Knudsen, G. M., 2021, In: European Neuropsychopharmacology. 42, p. 1-11

  Research output: Contribution to journal › Journal article › Research › peer-review
  22 Citations (Scopus)
• 2020

  KDM4A regulates the maternal-to-zygotic transition by protecting broad H3K4me3 domains from H3K9me3 invasion in oocytes

  Sankar, A., Lerdrup, M., Manaf, A., Johansen, J. V., Gonzalez, J. M., Borup, R., Blanshard, R., Klungland, A., Hansen, K., Andersen, C. Y., Dahl, J. A., Helin, K. & Hoffmann, E. R., 2020, In: Nature Cell Biology. 22, 4, p. 380-388 9 p.

  Research output: Contribution to journal › Journal article › peer-review

  Open Access
  81 Citations (Scopus)

• Mutations in a Single Signaling Pathway Allow Cell Growth in Heavy Water

  Kampmeyer, C., Johansen, J. V., Holmberg, C., Karlson, M., Gersing, S. K., Bordallo, H. N., Kragelund, B. B., Lerche, M. H., Jourdain, I., Winther, J. R. & Hartmann-Petersen, R., 2020, In: A C S Synthetic Biology. 9, 4, p. 733-748 16 p.

  Research output: Contribution to journal › Journal article › peer-review
  15 Citations (Scopus)
• 2019

  PLZF targets developmental enhancers for activation during osteogenic differentiation of human mesenchymal stem cells

  Agrawal-Singh, S., Lerdrup, M., Gomes, A-L. R., van de Werken, H. J. G., Johansen, J. V., Andersson, R., Sandelin, A., Helin, K. & Hansen, K., 2019, In: eLife. 8, p. 1-32 32 p., e40364.

  Research output: Contribution to journal › Journal article › peer-review

  Open Access

  File
  31 Citations (Scopus)

  191 Downloads (Pure)

• Tracing the cellular dynamics of sebaceous gland development in normal and perturbed states

  Andersen, M. S., Hannezo, E., Ulyanchenko, S., Estrach, S., Antoku, Y., Pisano, S., Boonekamp, K. E., Sendrup, S., Maimets, M., Pedersen, M. T., Johansen, J. V., Clement, D. L., Feral, C. C., Simons, B. D. & Jensen, K. B., 2019, In: Nature Cell Biology. 21, 8, p. 924-932

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access
  25 Citations (Scopus)
• 2018

  Accurate Recycling of Parental Histones Reproduces the Histone Modification Landscape during DNA Replication

  Reverón-Gómez, N., González-Aguilera, C., Stewart-Morgan, K. R., Petryk, N., Flury, V., Graziano, S., Johansen, J. V., Jakobsen, J. S., Alabert, C. & Groth, A., 2018, In: Molecular Cell. 72, 2, p. 239-249 11 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  165 Citations (Scopus)

  335 Downloads (Pure)

• Histone H4K20 methylation mediated chromatin compaction threshold ensures genome integrity by limiting DNA replication licensing

  Shoaib, M., Walter, D., Gillespie, P. J., Izard, F., Fahrenkrog, B., Lleres, D., Lerdrup, M., Johansen, J. V., Hansen, K., Julien, E., Blow, J. J. & Sørensen, C. S., 2018, In: Nature Communications. 9, 1, p. 1-11 11 p., 3704.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  69 Citations (Scopus)

  280 Downloads (Pure)

• YAP/TAZ-Dependent Reprogramming of Colonic Epithelium Links ECM Remodeling to Tissue Regeneration

  Yui, S., Azzolin, L., Maimets, M., Pedersen, M. T., Fordham, R. P., Hansen, S. L., Larsen, H. L., Guiu, J., Alves, M. R. P., Rundsten, C. F., Johansen, J. V., Li, Y., Madsen, C. D., Nakamura, T., Watanabe, M., Nielsen, O. H., Schweiger, P. J., Piccolo, S. & Jensen, K. B., 1 Jan 2018, In: Cell Stem Cell. 22, 1, p. 35-49. e7 23 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  442 Citations (Scopus)

  561 Downloads (Pure)
• 2017

  CRISPR/Cas9 Engineering of Adult Mouse Liver Demonstrates That the Dnajb1–Prkaca Gene Fusion Is Sufficient to Induce Tumors Resembling Fibrolamellar Hepatocellular Carcinoma

  Engelholm, L. H., Riaz, A., Serra, D., Dagnæs-Hansen, F., Johansen, J. V., Santoni-Rugiu, E., Hansen, S. H., Niola, F. & Frödin, M., 1 Dec 2017, In: Gastroenterology. 153, 6, p. 1662-1673.e10

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  86 Citations (Scopus)

  366 Downloads (Pure)

• EZH2 is a potential therapeutic target for H3K27M-mutant pediatric gliomas

  Mohammad, F., Weissmann, S., Leblanc, B. O., Pandey, D. P., Højfeldt, J. W., Comet, I., Zheng, C., Johansen, J. V., Rapin, N. P. J-P., Porse, B. T., Tvardovskiy, A., Jensen, O. N., Olaciregui, N. G., Lavarino, C., Suñol, M., de Torres, C., Mora, J., Carcaboso, A. M. & Helin, K., Apr 2017, In: Nature Medicine. 23, 4, p. 483-492 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  376 Citations (Scopus)

• JMJD-5/KDM8 regulates H3K36me2 and is required for late steps of homologous recombination and genome integrity

  Amendola, P. G., Zaghet, N., Ramalho, J. J., Johansen, J. V., Boxem, M. & Salcini, A. E., Feb 2017, In: P L o S Genetics. 13, 2, 24 p., e1006632.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  28 Citations (Scopus)

  199 Downloads (Pure)

• UBL/BAG-domain co-chaperones cause cellular stress upon overexpression through constitutive activation of Hsf1

  Poulsen, E. G., Kampmeyer, C., Kriegenburg, F., Johansen, J. V., Hofmann, K., Holmberg, C. & Hartmann-Petersen, R., Jan 2017, In: Cell Stress & Chaperones. 22, 1, p. 143-154 12 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access
  12 Citations (Scopus)
• 2016

  An interactive environment for agile analysis and visualization of ChIP-sequencing data

  Lerdrup, M., Johansen, J. V., Agrawal-Singh, S. & Hansen, K., Apr 2016, In: Nature Structural and Molecular Biology. 23, 4, p. 349-57 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  180 Citations (Scopus)

• BRPF3-HBO1 regulates replication origin activation and histone H3K14 acetylation

  Feng, Y., Vlassis, A., Roques, C., Lalonde, M. E., Gonzalez Aguilera, C., Lambert, J. P., Lee, S-B., Zhao, X., Alabert, C., Johansen, J. V., Paquet, E., Yang, X. J., Gingras, A. C., Côté, J. & Groth, A., 2016, In: EMBO Journal. 35, 2, p. 176-192 17 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  96 Citations (Scopus)

• Continual removal of H3K9 promoter methylation by Jmjd2 demethylases is vital for ESC self-renewal and early development

  Pedersen, M. T., Kooistra, S. M., Radzisheuskaya, A., Laugesen, A., Johansen, J. V., Hayward, D. G., Nilsson, J., Agger, K. & Helin, K., 15 Jul 2016, In: E M B O Journal. 35, 14, p. 1550-64 15 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  84 Citations (Scopus)

• Jmjd2/Kdm4 demethylases are required for expression of Il3ra and survival of acute myeloid leukemia cells

  Agger, K., Miyagi, S., Pedersen, M. T., Kooistra, S. M., Johansen, J. V. & Helin, K., 1 Jun 2016, In: Genes & Development. 30, 11, p. 1278-88 11 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  62 Citations (Scopus)

  213 Downloads (Pure)
• 2015

  Cyclin F suppresses B-Myb activity to promote cell cycle checkpoint control

  Klein, D. K., Hoffmann, S., Ahlskog, J. K., O'Hanlon, K., Quaas, M., Larsen, B. D., Rolland, B., Rösner, H. I., Walter, D., Kousholt, A. N., Menzel, T., Lees, M., Johansen, J. V., Rappsilber, J., Engeland, K. & Sørensen, C. S., 2015, In: Nature Communications. 6, p. 5800

  Research output: Contribution to journal › Journal article › Research › peer-review
  61 Citations (Scopus)

• Loss of PRDM11 promotes MYC-driven lymphomagenesis

  Fog-Tonnesen, C. K., Asmar, F., Côme, C. R. M., Jensen, K. T., Johansen, J. V., Bou Kheir, T., Jacobsen, L., Friis, C., Louw, A., Rosgaard, L., Øbro, N. F., Marquart, H. V., Anthonsen, K., Braat, A. K., van Lohuizen, M., Ralfkiaer, E., Grønbæk, K. & Lund, A. H., 19 Feb 2015, In: Blood. 125, 8, p. 1272-81 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  21 Citations (Scopus)

• Loss of TET2 in hematopoietic cells leads to DNA hypermethylation of active enhancers and induction of leukemogenesis

  Rasmussen, K. D., Jia, G., Johansen, J. V., Pedersen, M. T., Rapin, N., Bagger, F. O., Porse, B. T., Bernard, O. A., Christensen, J. & Helin, K., 17 Apr 2015, In: Genes & Development. p. 910-922 13 p., 29.

  Research output: Contribution to journal › Journal article › Research › peer-review
  222 Citations (Scopus)

• SWI/SNF Subunits SMARCA4, SMARCD2 and DPF2 Collaborate in MLL-Rearranged Leukaemia Maintenance

  Cruickshank, V. A., Sroczynska, P., Sankar, A., Miyagi, S., Rundsten, C. F., Johansen, J. V. & Helin, K., 2015, In: PLOS ONE. 10, 11, p. e0142806

  Research output: Contribution to journal › Journal article › peer-review
  22 Citations (Scopus)
• 2014

  A Screen Identifies the Oncogenic Micro-RNA miR-378a-5p as a Negative Regulator of Oncogene-Induced Senescence

  Kooistra, S. M., Rudkjær, L. C., Lees, M. J., Steinhauer, C., Johansen, J. V. & Helin, K., 2014, In: PLOS ONE. 9, 3, p. 1-7 7 p., e91034.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  19 Citations (Scopus)

  3357 Downloads (Pure)

• Gene Silencing Triggers Polycomb Repressive Complex 2 Recruitment to CpG Islands Genome Wide

  Riising, E. M., Vacher-Comet, I., Leblanc, B. O., Wu, X., Johansen, J. V. & Helin, K., 3 Jul 2014, In: Molecular Cell.

  Research output: Contribution to journal › Journal article › Research › peer-review
  319 Citations (Scopus)

• The Demethylase JMJD2C Localizes to H3K4me3 Positive Transcription Start Sites and Is Dispensable for Embryonic Development

  Pedersen, M. T., Agger, K., Laugesen, A., Johansen, J. V., Cloos, P. A. C., Christensen, J. A. & Helin, K., 6 Jan 2014, In: Molecular and Cellular Biology.

  Research output: Contribution to journal › Journal article › peer-review
  60 Citations (Scopus)

• The Histone Lysine Demethylase JMJD3/KDM6B Is Recruited to p53 Bound Promoters and Enhancer Elements in a p53 Dependent Manner

  Williams, K., Christensen, J., Rappsilber, J., Nielsen, A. L., Johansen, J. V. & Helin, K., 2014, In: PLOS ONE. 9, 5, p. e96545

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  70 Citations (Scopus)

  2795 Downloads (Pure)
• 2013

  Fbxl10/Kdm2b recruits polycomb repressive complex 1 to CpG islands and regulates H2A ubiquitylation

  Wu, X., Johansen, J. V. & Helin, K., 28 Mar 2013, In: Molecular Cell. 49, 6, p. 1134-46 13 p.

  Research output: Contribution to journal › Journal article › peer-review
  314 Citations (Scopus)

• Loss Of Tet2 Collaborates With AML1-ETO In Inducing Leukemogenesis

  Rasmussen, K. D., Jia, G., Johansen, J. V., Bernard, O. A. & Helin, K., 15 Nov 2013, In: Blood. 122, 21

  Research output: Contribution to journal › Journal article › peer-review

• The Histone Demethylase Jarid1b Ensures Faithful Mouse Development by Protecting Developmental Genes from Aberrant H3K4me3

  Albert, M., Schmitz, S. U., Kooistra, S. M., Malatesta, M., Morales Torres, C., Rekling, J. C., Johansen, J. V., Abarrategui, I. & Helin, K., Apr 2013, In: P L o S Genetics. 9, 4, p. 1-15 16 p., e1003461.

  Research output: Contribution to journal › Journal article › peer-review
  103 Citations (Scopus)
• 2011

  A genetic screen identifies BRCA2 and PALB2 as key regulators of G2 checkpoint maintenance

  Menzel, T., Nähse-Kumpf, V., Kousholt, A. N., Klein, D. K., Lund-Andersen, C., Lees, M., Johansen, J. V., Syljuåsen, R. G. & Sørensen, C. S., 1 Jan 2011, In: E M B O Reports. 12, 7, p. 705-12 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  58 Citations (Scopus)

• Jarid1b targets genes regulating development and is involved in neural differentiation

  Schmitz, S. U., Albert, M., Malatesta, M., Morey Ramonell, L., Johansen, J. V., Bak, M., Tommerup, N., Abarrategui Garcia, I. & Helin, K., 2011, In: E M B O Journal. 30, 22, p. 4586-600 15 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  162 Citations (Scopus)

• MMSET is highly expressed and associated with aggressiveness in neuroblastoma

  Hudlebusch, H. R., Skotte, J., Santoni-Rugiu, E., Zimling, Z. G., Lees, M. J., Simon, R., Sauter, G., Rota, R., De Ioris, M. A., Quarto, M., Johansen, J. V., Jorgensen, M., Rechnitzer, C., Maroun, L. L., Schrøder, H., Petersen, B. L., Helin, K., Hudlebusch, H. R., Skotte, J., Santoni-Rugiu, E. & 14 others, Zimling, Z. G., Lees, M. J., Simon, R., Sauter, G., Rota, R., De Ioris, M. A., Quarto, M., Johansen, J. V., Jørgensen, M., Rechnitzer, C., Maroun, L. L., Schrøder, H., Petersen, B. L. & Helin, K., 2011, In: Cancer Research. 71, 12, p. 4226-35 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  58 Citations (Scopus)

• TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity

  Williams, K., Christensen, J., Pedersen, M. T., Johansen, J. V., Cloos, P. A. C., Rappsilber, J. & Helin, K., 19 May 2011, In: Nature. 473, 7347, p. 343-8 6 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  856 Citations (Scopus)

• The histone methyltransferase and putative oncoprotein MMSET is overexpressed in a large variety of human tumors

  Hudlebusch, H. R., Santoni-Rugiu, E., Simon, R., Ralfkiær, E., Rossing, H. H., Johansen, J. V., Jørgensen, M., Sauter, G. & Helin, K., 2011, In: Clinical Cancer Research. 17, 9, p. 2919-33 15 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  114 Citations (Scopus)
• 2010

  JARID2 regulates binding of the Polycomb repressive complex 2 to target genes in ES cells

  Pasini, D., Cloos, P. A. C., Walfridsson, J., Olsson, L., Bukowski, J-P., Johansen, J. V., Bak, M., Tommerup, N., Rappsilber, J. & Helin, K., 2010, In: Nature. 464, 7286, p. 306-10 4 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  469 Citations (Scopus)
• 2009

  RSK is a principal effector of the RAS-ERK pathway for eliciting a coordinate promotile/invasive gene program and phenotype in epithelial cells

  Doehn, U., Hauge, C., Frank, S. R., Jensen, C. A. J., Duda, K., Nielsen, J. V., Cohen, M. S., Johansen, J. V., Winther, B. R., Lund, L. R., Winther, O., Taunton, J., Hansen, S. H. & Frödin, M., 2009, In: Molecular Cell. 35, 4, p. 511-22 11 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  187 Citations (Scopus)
• 2008

  Prediction of fat oxidation capacity using ¹H-NMR and LC-MS lipid metabolomic data combined with phenotypic data

  Pers, T. H., Martin, F. P., Verdich, C., Holst, C., Johansen, J. V., Astrup, A., Polak, J., Martinez, J. A., Rezzi, S., Blaak, E. E., Saris, W. H. M., Kochhar, S., Macdonald, I. A., Sørensen, T. I. A. & Ramadan, Z., 2008, In: Chemometrics and Intelligent Laboratory Systems. 93, 1, p. 34-42 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  5 Citations (Scopus)