Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Research output
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Nano-Gs Protein Peptidomimetics: Rational Design of Gα C-Terminus-Derived Peptides Mimicking Key Components of Gs-β2AR Interactions
Tran, P. T., Danielsen, M., Tiemann, J. K. S., Ibrahim, P., Rasmussen, S. G. F., Kubiak, X., Batebi, H., Gadais, C., Ballet, S., Hildebrand, P. W., Pedersen, D. S. & Mathiesen, J. M., 2026, (E-pub ahead of print) In: Angewandte Chemie International Edition. 13 p., e23510.Research output: Contribution to journal › Journal article › Research › peer-review
Open Access -
Detailed functional characterization of four nanobodies as positive allosteric modulators of the human calcium-sensing receptor
Du, W., Rahman, S. N., Barker, E., Bräuner-Osborne, H., Mathiesen, J. M., Ward, D. T. & Jensen, A. A., 2025, In: Biochemical Pharmacology. 231, 12 p., 116619.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile2 Citations (Scopus)107 Downloads (Pure) -
Heterogeneous Origins of Calcium Homeostasis Disorders Arising From 5 Heterozygous Calcium-Sensing Receptor Variants
Du, W., Boisen, I. M., Rahman, S. N., Poulsen, N. N., Mathiesen, J. M., Jensen, M. B., Bräuner-Osborne, H. & Jensen, A. A., 2025, In: The Journal of clinical endocrinology and metabolism. 110, 7, p. 1865–1880Research output: Contribution to journal › Journal article › Research › peer-review
1 Citation (Scopus) -
A µ-opioid receptor modulator that works cooperatively with naloxone
O’Brien, E. S., Rangari, V. A., El Daibani, A., Eans, S. O., Hammond, H. R., White, E., Wang, H., Shiimura, Y., Krishna Kumar, K., Jiang, Q., Appourchaux, K., Huang, W., Zhang, C., Kennedy, B. J., Mathiesen, J. M., Che, T., McLaughlin, J. P., Majumdar, S. & Kobilka, B. K., 2024, In: Nature. 631, 8021, p. 686-693Research output: Contribution to journal › Journal article › Research › peer-review
Open Access32 Citations (Scopus) -
Allosteric modulation and G-protein selectivity of the Ca2+-sensing receptor
He, F., Wu, C. G., Gao, Y., Rahman, S. N., Zaoralová, M., Papasergi-Scott, M. M., Gu, T. J., Robertson, M. J., Seven, A. B., Li, L., Mathiesen, J. M. & Skiniotis, G., 2024, In: Nature. 626, p. 1141–1148Research output: Contribution to journal › Journal article › Research › peer-review
Open Access48 Citations (Scopus) -
Bitopic Ligands Support the Presence of a Metastable Binding Site at the β2 Adrenergic Receptor
Gaiser, B. I., Danielsen, M., Xu, X., Røpke Jørgensen, K., Fronik, P., Märcher-Rørsted, E., Wróbel, T. M., Liu, X., Mosolff Mathiesen, J. & Sejer Pedersen, D., 2024, In: Journal of Medicinal Chemistry. 67, 13, p. 11053–11068Research output: Contribution to journal › Journal article › Research › peer-review
6 Citations (Scopus) -
Discovery and pharmacological characterization of nanobodies acting as potent positive allosteric modulators of the calcium-sensing receptor
Mos, I., Zögg, T., Wohlkönig, A., Egholm, A. M. H., Rahman, S. N., Pardon, E., Steyaert, J., Bräuner-Osborne, H. & Mathiesen, J. M., 8 Jul 2024, bioRxiv, 37 p.Research output: Working paper › Preprint
File4 Downloads (Pure) -
Mechanistic insights into G-protein coupling with an agonist-bound G-protein-coupled receptor
Batebi, H., Pérez-Hernández, G., Rahman, S. N., Lan, B., Kamprad, A., Shi, M., Speck, D., Tiemann, J. K. S., Guixà-González, R., Reinhardt, F., Stadler, P. F., Papasergi-Scott, M. M., Skiniotis, G., Scheerer, P., Kobilka, B. K., Mathiesen, J. M., Liu, X. & Hildebrand, P. W., 2024, In: Nature Structural and Molecular Biology. 31, p. 1692–1701Research output: Contribution to journal › Journal article › Research › peer-review
Open Access21 Citations (Scopus)