Research output per year
Research output per year
Personal profile
Primary fields of research
The research activities of my group are directed towards interrogating the signaling pathways controlling cellular and whole body glucose and lipid homeostasis in cell-based and animal models. To resolve the physiological role of genes, proteins, and pathways that regulate insulin action and adiposity, we use transgenic animals harboring mutant and wild-type forms of candidate genes or knockout deletions. We are developing in vitro and in vivo methods to assess the functional role of novel targets in type 2 diabetes and obesity pathogenesis as well as performing clinical and experimental studies for genotype/phenotype interactions to identify diabetes risk and mechanisms underlying diabetes pathogenesis.
Education/Academic qualification
PhD, University of Copenhagen
Award Date: 27 Nov 2009
Master of Science, University of Copenhagen
Award Date: 30 Nov 2004
Keywords
- Faculty of Health and Medical Sciences
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Research output
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Effect of nicotinamide riboside on airway inflammation in COPD: a randomized, placebo-controlled trial
Norheim, K. L., Ben Ezra, M., Heckenbach, I., Andreasson, L. M., Eriksen, L. L., Dyhre-Petersen, N., Damgaard, M. V., Berglind, M., Pricolo, L., Sampson, D., Dellinger, R. W., Sverrild, A., Treebak, J. T., Ditlev, S. B., Porsbjerg, C. & Scheibye-Knudsen, M., 2024, (E-pub ahead of print) In: Nature Aging.Research output: Contribution to journal › Letter › Research › peer-review
Open Access -
Effect of resveratrol on insulin action in primary myotubes from lean individuals and individuals with severe obesity
Park, S., Jevtovic, F., Krassovskaia, P. M., Chaves, A. B., Zheng, D., Treebak, J. T. & Houmard, J. A., 2024, In: American Journal of Physiology - Endocrinology and Metabolism. 326, 3, p. E398-E406 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile1 Citation (Scopus)11 Downloads (Pure) -
Impaired skeletal muscle regeneration in diabetes: From cellular and molecular mechanisms to novel treatments
Espino-Gonzalez, E., Dalbram, E., Mounier, R., Gondin, J., Farup, J., Jessen, N. & Treebak, J. T., 2024, In: Cell Metabolism. 36, 6, p. 1204-1236Research output: Contribution to journal › Review › Research › peer-review
Open AccessFile4 Citations (Scopus)5 Downloads (Pure) -
Metabolic plasticity and obesity-associated changes in diurnal postexercise metabolism in mice
Pendergrast, L. A., Ashcroft, S. P., Ehrlich, A. M., Treebak, J. T., Krook, A., Dollet, L. & Zierath, J. R., 2024, In: Metabolism: Clinical and Experimental. 155, 12 p., 155834.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile1 Citation (Scopus)25 Downloads (Pure) -
Mitochondrial adaptations in thermogenic tissues during cancer cachexia and upon different ambient temperatures
Irazoki, A., Frank, E., Pham, T. C. P., Rydal Jørgensen, A-S., Ehrlich, A. M., Hansen, C. H. F., Treebak, J. T., Richter, E. A. & Sylow, L., 2024, In: B B A - Molecular Basis of Disease. 1870, 8, p. 8-8Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Trigonelline is an NAD+ precursor that improves muscle function during ageing and is reduced in human sarcopenia
Membrez, M., Migliavacca, E., Christen, S., Yaku, K., Trieu, J., Lee, A. K., Morandini, F., Giner, M. P., Stiner, J., Makarov, M. V., Garratt, E. S., Vasiloglou, M. F., Chanvillard, L., Dalbram, E., Ehrlich, A. M., Sanchez-Garcia, J. L., Canto, C., Karagounis, L. G., Treebak, J. T., Migaud, M. E. & 15 others, , 2024, In: Nature Metabolism. 6, 3, p. 433–447Research output: Contribution to journal › Letter › Research › peer-review
Open AccessFile19 Citations (Scopus)7 Downloads (Pure) -
NAMPT-dependent NAD+ biosynthesis controls circadian metabolism in a tissue-specific manner
Basse, A. L., Nielsen, K. N., Karavaeva, I., Ingerslev, L. R., Ma, T., Havelund, J. F., Nielsen, T. S., Frost, M., Peics, J., Dalbram, E., Dall, M., Zierath, J. R., Barrès, R., Færgeman, N. J., Treebak, J. T. & Gerhart-Hines, Z., 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 14, e2220102120.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile11 Citations (Scopus)65 Downloads (Pure) -
Oral supplementation of nicotinamide riboside alters intestinal microbial composition in rats and mice, but not humans
Peluso, A. A., Lundgaard, A. T., Babaei, P., Mousovich-Neto, F., Rocha, A. L., Damgaard, M. V., Bak, E. G., Gnanasekaran, T., Dollerup, O. L., Trammell, S. A. J., Nielsen, T. S., Kern, T., Abild, C. B., Sulek, K., Ma, T., Gerhart-Hines, Z., Gillum, M. P., Arumugam, M., Ørskov, C., McCloskey, D. & 4 others, , 2023, In: npj Aging. 9, 21 p., 7.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile10 Citations (Scopus)39 Downloads (Pure)