Research output per year
Research output per year
Research output
- 27 results
Search results
-
2024
De novo design of high-affinity binders of bioactive helical peptides
Vázquez Torres, S., Leung, P. J. Y., Venkatesh, P., Lutz, I. D., Hink, F., Huynh, H. H., Becker, J., Yeh, A. H. W., Juergens, D., Bennett, N. R., Hoofnagle, A. N., Huang, E., MacCoss, M. J., Expòsit, M., Lee, G. R., Bera, A. K., Kang, A., De La Cruz, J., Levine, P. M., Li, X. & 10 others, , 2024, In: Nature. 626, 7998, p. 435-442Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile30 Citations (Scopus)18 Downloads (Pure) -
Engineering mRNA display for GPCR drug discovery - de novo discovery of cyclic peptide GLP1R binders
Meron, E., Nygaard, M. M., Rønn Madsen, M., Leurs, U., Christensen-Dalsgaard, M., Lundh, M. & Rogers, J. M., 2024, In: Journal of Peptide Science. 30, Suppl. 2, 538-P2.171.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Mixed Stereochemistry Macrocycle Acts as a Helix-Stabilizing Peptide N-Cap
Hink, F., Aduriz-Arrizabalaga, J., Lopez, X., Suga, H., De Sancho, D. & Rogers, J. M., 2024, In: Journal of the American Chemical Society. 146, 35, p. 24348–24357Research output: Contribution to journal › Journal article › Research › peer-review
1 Citation (Scopus) -
Special Issue on RNA-Based Catalysts that Revolutionized the Discovery of Bioactive Peptides
Jongkees, S. A. K., Rogers, J. M. & Walport, L. J., 2024, In: Israel Journal of Chemistry. 64, 8-9, e202400064.Research output: Contribution to journal › Editorial › Research › peer-review
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2023
Substrates and Cyclic Peptide Inhibitors of the Oligonucleotide-Activated Sirtuin 7**
Bolding, J. E., Nielsen, A. L., Jensen, I., Hansen, T. N., Ryberg, L. A., Jameson, S. T., Harris, P., Peters, G. H. J., Denu, J. M., Rogers, J. M. & Olsen, C. A., 2023, In: Angewandte Chemie - International Edition. 62, 49, e202314597.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile4 Citations (Scopus)19 Downloads (Pure) -
2022
A context-dependent and disordered ubiquitin-binding motif
Dreier, J. E., Prestel, A., Martins, J. M., Brøndum, S. S., Nielsen, O., Garbers, A. E., Suga, H., Boomsma, W., Rogers, J. M., Hartmann-Petersen, R. & Kragelund, B. B., 2022, In: Cellular and molecular life sciences : CMLS. 79, 9, 21 p., 484.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile10 Citations (Scopus)61 Downloads (Pure) -
2021
In vivo modulation of ubiquitin chains by N -methylated non-proteinogenic cyclic peptides
Rogers, J. M., Nawatha, M., Lemma, B., Vamisetti, G. B., Livneh, I., Barash, U., Vlodavsky, I., Ciechanover, A., Fushman, D., Suga, H. & Brik, A., 2021, In: RSC Chemical Biology. 2, 2, p. 513-522 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile20 Citations (Scopus)42 Downloads (Pure) -
Structure-activity relationship of ipglycermide binding to phosphoglycerate mutases
Wiedmann, M., Dranchak, P. K., Aitha, M., Queme, B., Collmus, C. D., Kashipathy, M. M., Kanter, L., Lamy, L., Rogers, J. M., Tao, D., Battaile, K. P., Rai, G., Lovell, S., Suga, H. & Inglese, J., 2021, In: The Journal of Biological Chemistry. 296, 14 p., 100628.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile4 Citations (Scopus)23 Downloads (Pure) -
2020
Affinity Maturation of Macrocyclic Peptide Modulators of Lys48-Linked Diubiquitin by a Twofold Strategy
Huang, Y., Nawatha, M., Livneh, I., Rogers, J. M., Sun, H., Singh, S. K., Ciechanover, A., Brik, A. & Suga, H., 26 Jun 2020, In: Chemistry - A European Journal. 26, 36, p. 8022-8027 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
17 Citations (Scopus) -
Initiating ribosomal peptide synthesis with exotic building blocks
Tsiamantas, C., Rogers, J. M. & Suga, H., 21 Apr 2020, In: Chemical Communications. 56, 31, p. 4265-4272 8 p.Research output: Contribution to journal › Review › Research › peer-review
14 Citations (Scopus) -
Peptide Folding and Binding Probed by Systematic Non-canonical Mutagenesis
Rogers, J. M., 2020, In: Frontiers in Molecular Biosciences. 7, 9 p., 100.Research output: Contribution to journal › Review › Research › peer-review
Open AccessFile3 Citations (Scopus)112 Downloads (Pure) -
Ribosomal Incorporation of Aromatic Oligoamides as Peptide Sidechain Appendages
Tsiamantas, C., Kwon, S., Rogers, J. M., Douat, C., Huc, I. & Suga, H., 16 Mar 2020, In: Angewandte Chemie - International Edition. 59, 12, p. 4860-4864 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
22 Citations (Scopus) -
2019
De novo macrocyclic peptides that specifically modulate Lys48-linked ubiquitin chains
Nawatha, M., Rogers, J. M., Bonn, S. M., Livneh, I., Lemma, B., Mali, S. M., Vamisetti, G. B., Sun, H., Bercovich, B., Huang, Y., Ciechanover, A., Fushman, D., Suga, H. & Brik, A., 1 Jul 2019, In: Nature Chemistry. 11, 7, p. 644-652 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
64 Citations (Scopus) -
Molecular technologies for pseudo-natural peptide synthesis and discovery of bioactive compounds against undruggable targets
Rogers, J. M. & Suga, H., 6 Feb 2019, Molecular Technology: Materials Innovation. Wiley, p. 329-370 42 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
1 Citation (Scopus) -
2018
Nonproteinogenic deep mutational scanning of linear and cyclic peptides
Rogers, J. M., Passioura, T. & Suga, H., 23 Oct 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 43, p. 10959-10964 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open Access54 Citations (Scopus) -
Ribosomal synthesis and folding of peptide-helical aromatic foldamer hybrids
Rogers, J. M., Kwon, S., Dawson, S. J., Mandal, P. K., Suga, H. & Huc, I., 1 Apr 2018, In: Nature Chemistry. 10, 4, p. 405-412 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
73 Citations (Scopus) -
2015
Discovering functional, non-proteinogenic amino acid containing, peptides using genetic code reprogramming
Rogers, J. M. & Suga, H., 5 Aug 2015, In: Organic and Biomolecular Chemistry. 13, 36, p. 9353-9363 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
59 Citations (Scopus) -
Model foldamers: Applications and structures of stable macrocyclic peptides identified using in vitro selection
Jongkees, S. A. K., Hipolito, C. J., Rogers, J. M. & Suga, H., 1 May 2015, In: New Journal of Chemistry. 39, 5, p. 3197-3207 11 p.Research output: Contribution to journal › Review › Research › peer-review
13 Citations (Scopus) -
2014
Coupled folding and binding of the disordered protein PUMA does not require particular residual structure
Rogers, J. M., Wong, C. T. & Clarke, J., 9 Apr 2014, In: Journal of the American Chemical Society. 136, 14, p. 5197-5200 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open Access95 Citations (Scopus) -
High thermodynamic stability of parametrically designed helical bundles
Huang, P. S., Oberdorfer, G., Xu, C., Pei, X. Y., Nannenga, B. L., Rogers, J. M., DiMaio, F., Gonen, T., Luisi, B. & Baker, D., 24 Oct 2014, In: Science. 346, 6208, p. 481-485 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
214 Citations (Scopus) -
Interplay between partner and ligand facilitates the folding and binding of an intrinsically disordered protein
Rogers, J. M., Oleinikovas, V., Shammas, S. L., Wong, C. T., De Sancho, D., Baker, C. M. & Clarke, J., 28 Oct 2014, In: Proceedings of the National Academy of Sciences of the United States of America. 111, 43, p. 15420-15425 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open Access131 Citations (Scopus) -
2013
Folding and binding of an intrinsically disordered protein: Fast, but not 'diffusion-limited'
Rogers, J. M., Steward, A. & Clarke, J., 30 Jan 2013, In: Journal of the American Chemical Society. 135, 4, p. 1415-1422 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open Access103 Citations (Scopus) -
2012
Protein folding: Adding a nucleus to guide helix docking reduces landscape roughness
Wensley, B. G., Kwa, L. G., Shammas, S. L., Rogers, J. M. & Clarke, J., 26 Oct 2012, In: Journal of Molecular Biology. 423, 3, p. 273-283 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open Access15 Citations (Scopus) -
Separating the effects of internal friction and transition state energy to explain the slow, frustrated folding of spectrin domains
Wensley, B. G., Kwa, L. G., Shammas, S. L., Rogers, J. M., Browning, S., Yang, Z. & Clarke, J., 30 Oct 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 44, p. 17795-17799 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open Access36 Citations (Scopus) -
Slow, reversible, coupled folding and binding of the spectrin tetramerization domain
Shammas, S. L., Rogers, J. M., Hill, S. A. & Clarke, J., 21 Nov 2012, In: Biophysical Journal. 103, 10, p. 2203-2214 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open Access40 Citations (Scopus) -
Two immunoglobulin tandem proteins with a linking β-strand reveal unexpected differences in cooperativity and folding pathways
Steward, A., Chen, Q., Chapman, R. I., Borgia, M. B., Rogers, J. M., Wojtala, A., Wilmanns, M. & Clarke, J., 10 Feb 2012, In: Journal of Molecular Biology. 416, 1, p. 137-147 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open Access11 Citations (Scopus) -
2010
Experimental detection of knotted conformations in denatured proteins
Mallam, A. L., Rogers, J. M. & Jackson, S. E., 4 May 2010, In: Proceedings of the National Academy of Sciences of the United States of America. 107, 18, p. 8189-8194 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open Access94 Citations (Scopus)