Research output per year
Research output per year
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Research output
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A synthetic lethal dependency on casein kinase 2 in response to replication-perturbing therapeutics in RB1-deficient cancer cells
Bulanova, D., Akimov, Y., Senkowski, W., Oikkonen, J., Gall-Mas, L., Timonen, S., Elmadani, M., Hynninen, J., Hautaniemi, S., Aittokallio, T. & Wennerberg, K., 2024, In: Science Advances. 10, 21, 15 p., eadj1564.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile11 Downloads (Pure) -
Defining the KRAS- and ERK-dependent transcriptome in KRAS-mutant cancers
Klomp, J. A., Klomp, J. E., Stalnecker, C. A., Bryant, K. L., Edwards, A. C., Drizyte-Miller, K., Hibshman, P. S., Diehl, J. N., Lee, Y. S., Morales, A. J., Taylor, K. E., Peng, S., Tran, N. L., Herring, L. E., Prevatte, A. W., Barker, N. K., Hover, L. D., Hallin, J., Chowdhury, S., Coker, O. & 13 others, , 2024, In: Science (New York, N.Y.). 384, 6700, p. eadk0775 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
9 Citations (Scopus) -
Ex vivo venetoclax sensitivity predicts clinical response in acute myeloid leukemia in the prospective VenEx trial
Kytölä, S., Vänttinen, I., Ruokoranta, T., Partanen, A., Holopainen, A., Saad, J., Kuusisto, M. E. L., Koskela, S., Räty, R., Itälä-Remes, M., Västrik, I., Suvela, M., Parsons, A., Porkka, K., Wennerberg, K., Heckman, C. A., Jalkanen, T., Huttunen, T., Ettala, P., Rimpiläinen, J. & 4 others, , 2024, (Accepted/In press) In: Blood.Research output: Contribution to journal › Journal article › Research › peer-review
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GDNF/GFRA1 signaling contributes to chemo- and radioresistance in glioblastoma
Avenel, I. C. N., Ewald, J. D., Ariey-Bonnet, J., Kristensen, I. H., Petterson, S. A., Thesbjerg, M. N., Burton, M., Thomassen, M., Wennerberg, K., Michaelsen, S. R. & Kristensen, B. W., 2024, In: Scientific Reports. 14, 1, 13 p., 17639.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile8 Downloads (Pure) -
Integrated drug profiling and CRISPR screening identify BCR::ABL1-independent vulnerabilities in chronic myeloid leukemia
Adnan Awad, S., Dufva, O., Klievink, J., Karjalainen, E., Ianevski, A., Pietarinen, P., Kim, D., Potdar, S., Wolf, M., Lotfi, K., Aittokallio, T., Wennerberg, K., Porkka, K. & Mustjoki, S., 2024, In: Cell Reports Medicine. 5, 5, 24 p., 101521.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile2 Citations (Scopus)3 Downloads (Pure) -
Robust scoring of selective drug responses for patient-tailored therapy selection
Chen, Y., He, L., Ianevski, A., Ayuda-Durán, P., Potdar, S., Saarela, J., Miettinen, J. J., Kytölä, S., Miettinen, S., Manninen, M., Heckman, C. A., Enserink, J. M., Wennerberg, K. & Aittokallio, T., 2024, In: Nature Protocols. 19, p. 60-82Research output: Contribution to journal › Journal article › Research › peer-review
3 Citations (Scopus) -
Single-cell transcriptomes identify patient-tailored therapies for selective co-inhibition of cancer clones
Ianevski, A., Nader, K., Driva, K., Senkowski, W., Bulanova, D., Moyano-Galceran, L., Ruokoranta, T., Kuusanmäki, H., Ikonen, N., Sergeev, P., Vähä-Koskela, M., Giri, A. K., Vähärautio, A., Kontro, M., Porkka, K., Pitkänen, E., Heckman, C. A., Wennerberg, K. & Aittokallio, T., 2024, In: Nature Communications. 15, 1, 16 p., 8579.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile1 Downloads (Pure) -
Venetoclax triggers sublethal apoptotic signaling in venetoclax-resistant acute myeloid leukemia cells and induces vulnerability to PARP inhibition and azacitidine
Tambe, M., Unterberger, S., Kriegbaum, M. C., Vänttinen, I., Olgac, E. J., Vähä-Koskela, M., Kontro, M., Wennerberg, K. & Heckman, C. A., 2024, In: Cell Death and Disease. 15, 10, 9 p., 750.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile1 Downloads (Pure)