Research output per year
Research output per year
Personal profile
Short presentation
Kristina Bennet Emdal's research is focused on using quantitative mass spectrometry to study cell signaling in cancer biology.
- Understanding TrkA and ALK receptor signaling in neuroblastoma cells
- Identification of disease-state biomarkers in patient-derived kidney samples
- Identification of drug-response signatures in acute myeloid leukemia patient samples
Primary fields of research
• Receptor tyrosine kinase signaling
• Phosphoproteomics
• Cancer biology
CV
2018 –
Postdoc, Olsen Group, Department of Proteomics, NNF Center for Protein Research, University of Copenhagen, Denmark
2015 – 2018
Postdoc Associate, White Lab, Department of Biological Engineering, Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA
2011 – 2015
PhD student, Olsen Group, Department of Proteomics, NNF Center for Protein Research, University of Copenhagen, Denmark
2008 – 2011
Research Assistant, Department of Breast Cancer Research, Danish Cancer Society, Copenhagen, Denmark
2008
M.Sc. Human Biology, University of Copenhagen, Denmark
Keywords
- Faculty of Health and Medical Sciences
- Phosphoproteomics
- Mass Spectrometry
- Cancer Biology
- Cell Signaling
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Multi-layered proteomics identifies insulin-induced upregulation of the EphA2 receptor via the ERK pathway which is dependent on low IGF1R level
Jørgensen, S. H., Emdal, K. B., Pedersen, A. K., Axelsen, L. N., Kildegaard, H. F., Demozay, D., Pedersen, T. Å., Grønborg, M., Slaaby, R., Nielsen, P. K. & Olsen, J. V., 2024, In: Scientific Reports. 14, 1, 20 p., 28856.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile -
Differential ultracentrifugation enables deep plasma proteomics through enrichment of extracellular vesicles
Kverneland, A. H., Østergaard, O., Emdal, K. B., Svane, I. M. & Olsen, J. V., 2023, In: Proteomics. 23, 7-8, 2200039.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile12 Citations (Scopus)50 Downloads (Pure) -
Phosphoproteomics of primary AML patient samples reveals rationale for AKT combination therapy and p53 context to overcome selinexor resistance
Emdal, K. B., Palacio-Escat, N., Wigerup, C., Eguchi, A., Nilsson, H., Bekker-Jensen, D. B., Rönnstrand, L., Kazi, J. U., Puissant, A., Itzykson, R., Saez-Rodriguez, J., Masson, K., Blume-Jensen, P. & Olsen, J. V., 2022, In: Cell Reports. 40, 6, 25 p., 111177.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile16 Citations (Scopus)50 Downloads (Pure) -
Causal integration of multi-omics data with prior knowledge to generate mechanistic hypotheses
Dugourd, A., Kuppe, C., Sciacovelli, M., Gjerga, E., Gabor, A., Emdal, K. B., Vieira, V., Bekker-Jensen, D. B., Kranz, J., Bindels, E. M. J., Costa, A. S. H., Sousa, A., Beltrao, P., Rocha, M., Olsen, J. V., Frezza, C., Kramann, R. & Saez-Rodriguez, J., 2021, In: Molecular Systems Biology. 17, 1, 17 p., e9730.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile76 Citations (Scopus)282 Downloads (Pure) -
Molecular switches in signaling networks as a mechanism of action for oncogenic mutations in proximity of tyrosine residues
Emdal, K. B. & Lundby, A., 2020, In: Molecular & Cellular Oncology. 7, 1, 3 p., e1692643.Research output: Contribution to journal › Comment/debate › Research › peer-review
Open AccessFile99 Downloads (Pure) -
Dynamic lineage priming is driven via direct enhancer regulation by ERK
Hamilton, W. B., Mosesson, Y., Monteiro, R. S., Emdal, K. B., Knudsen, T. E., Francavilla, C., Barkai, N., Olsen, J. V. & Brickman, J. M., 2019, In: Nature. 575, p. 355-360Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile46 Citations (Scopus)46 Downloads (Pure) -
Oncogenic Mutations Rewire Signaling Pathways by Switching Protein Recruitment to Phosphotyrosine Sites
Lundby, A., Franciosa, G., Emdal, K. B., Refsgaard, J. C., Gnosa, S. P., Bekker-Jensen, D. B., Secher, A., Maurya, S. R., Paul, I., Mendez, B. L., Kelstrup, C. D., Francavilla, C., Kveiborg, M., Montoya, G., Jensen, L. J. & Olsen, J. V., 2019, In: Cell. 179, 2, p. 543-560Research output: Contribution to journal › Journal article › Research › peer-review
File60 Citations (Scopus)477 Downloads (Pure) -
Identifying and targeting sporadic oncogenic genetic aberrations in mouse models of triple-negative breast cancer
Liu, H., Murphy, C. J., Karreth, F. A., Emdal, K. B., Yang, K., White, F. M., Elemento, O., Toker, A., Wulf, G. M. & Cantley, L. C., 2018, In: Cancer Discovery. 8, 3, p. 354-369 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
58 Citations (Scopus)