Research output per year
Research output per year
Personal profile
Short presentation
Research field: translational area between molecular pharmacology, clinical physiology and modern imaging techniques focusing on the endocrine system, cardiovascular system, and metabolism.
Expertise: peptide gut hormones related to nutrient metabolism involving ligand-receptor interactions, physiological actions, pathophysiological implications, and therapeutic potential.
Key words: Peptide hormones, incretin effect, hormone physiology, pharmacology, GIP, GLP-1, GLP-2
CV
2023-present: Assistant Professor, Gasbjerg Group, Department of Biomedical Sciences
2020-23: BRIDGE Translational Excellence Programme Fellowship, University of Copenhagen (UCPH). Project: The role of the intestinal hormones GIP and GLP-2 in postprandial splanchnic blood flow distribution and metabolism in humans
2019-20: Residency (klinisk basisudannelse/KBU): Internal medicine, Hvidovre Hospital; General Practice, Vanløse
2019: PhD degree, UCPH.
2015-19: PhD title: Glucose-dependent insulinotropic polypeptide – the main incretin hormone in man. Supervisors: Profs. Filip K Knop, Jens J Holst, Tina Vilsbøll, Mette M Rosenkilde, Ass. Prof. Mikkel Christensen. Affiliations: Center for Clinical Metabolic Research, Gentofte Hospital; Steno Diabetes Center Copenhagen; Dep. Biomedical Sciences, UCPH
2015: Medical Doctor
2012: Master thesis: Glucose-dependent insulinotropic polypeptide receptor antagonists. Supervisor: Prof. Mette M Rosenkilde, Dep. Neuroscience and Pharmacology, UCPH
2008-2015: Medical school, UCPH
Possible conflicts of interest
Co-founder of Antag Therapeutics, CVR 38402056
Education/Academic qualification
Medicine
1 Feb 2008 → 9 Jan 2015
Award Date: 9 Jan 2015
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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GLP-1 and GIP receptor signaling in beta cells – A review of receptor interactions and co-stimulation
Mayendraraj, A., Rosenkilde, M. M. & Gasbjerg, L. S., 2022, In: Peptides. 151, p. 1-10 170749.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile60 Citations (Scopus)60 Downloads (Pure) -
Worsening Postural Tachycardia Syndrome Is Associated With Increased Glucose-Dependent Insulinotropic Polypeptide Secretion
Breier, N. C., Paranjape, S. Y., Scudder, S., Mehr, S. E., Diedrich, A., Flynn, C. R., Okamoto, L. E., Hartmann, B., Gasbjerg, L. S. & Shibao, C. A., 2022, In: Hypertension. 79, 5, p. e89-e99Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile6 Citations (Scopus)26 Downloads (Pure) -
Effects of endogenous GIP in patients with type 2 diabetes
Stensen, S., Gasbjerg, L. S., Krogh, L. L., Skov-Jeppesen, K., Sparre-Ulrich, A. H., Jensen, M. H., Dela, F., Hartmann, B., Vilsbøll, T., Holst, J. J., Rosenkilde, M. M., Christensen, M. B. & Knop, F. K., Apr 2021, In: European Journal of Endocrinology. 185, 1, p. 33-45Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile26 Citations (Scopus)48 Downloads (Pure) -
GIP(3-30)NH2 is an efficacious GIP receptor antagonist in humans: a randomised, double-blinded, placebo-controlled, crossover study
Gasbjerg, L. S., Christensen, M. B., Hartmann, B., Lanng, A. R., Sparre-Ulrich, A. H., Gabe, M. B. N., Dela, F., Vilsbøll, T., Holst, J. J., Rosenkilde, M. M. & Knop, F. K., Feb 2018, In: Diabetologia. 61, 2, p. 413-423Research output: Contribution to journal › Journal article › Research › peer-review
74 Citations (Scopus) -
Evaluation of the incretin effect in humans using GIP and GLP-1 receptor antagonists
Gasbjerg, L. S., Bergmann, N. C., Stensen, S., Christensen, M. B., Rosenkilde, M. M., Holst, J. J., Nauck, M. & Knop, F. K., 2020, In: Peptides. 125, 10 p., 170183.Research output: Contribution to journal › Review › Research › peer-review
80 Citations (Scopus) -
Alcohol-induced fibroblast growth factor 21 secretion is increased in individuals with alcohol use disorder
Lanng, A. R., Gasbjerg, L. S., Sucksdorff, A. I. F., Svenningsen, J. S., Vilsbøll, T., Gillum, M. P. & Knop, F. K., 2024, In: Alcohol. 121, p. 69-74 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile6 Downloads (Pure) -
Altered desensitization and internalization patterns of rodent versus human glucose-dependent insulinotropic polypeptide (GIP) receptors. An important drug discovery challenge
Gasbjerg, L. S., Rasmussen, R. S., Dragan, A., Lindquist, P., Melchiorsen, J. U., Stepniewski, T. M., Schiellerup, S., Tordrup, E. K., Gadgaard, S., Kizilkaya, H. S., Willems, S., Zhong, Y., Wang, Y., Wright, S. C., Lauschke, V. M., Hartmann, B., Holst, J. J., Selent, J. & Rosenkilde, M. M., 2024, (E-pub ahead of print) In: British Journal of Pharmacology.Research output: Contribution to journal › Journal article › Research › peer-review
Open Access -
Characterization of genetic variants of GIPR reveals a contribution of β-arrestin to metabolic phenotypes
Kizilkaya, H. S., Sørensen, K. V., Madsen, J. S., Lindquist, P., Douros, J. D., Bork-Jensen, J., Berghella, A., Gerlach, P. A., Gasbjerg, L. S., Mokrosiński, J., Mowery, S. A., Knerr, P. J., Finan, B., Campbell, J. E., D’Alessio, D. A., Perez-Tilve, D., Faas, F., Mathiasen, S., Rungby, J., Sørensen, H. T. & 15 others, , 2024, In: Nature Metabolism. 6, p. 1268–1281Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile7 Citations (Scopus)10 Downloads (Pure)