Lars Fugger

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• 2024

  Ancient DNA reveals evolutionary origins of autoimmune diseases

  Barrie, W., Irving-Pease, E. K., Willerslev, E., Iversen, A. K. N. & Fugger, L., 2024, In: Nature Reviews Immunology. 24, p. 85-86

  Research output: Contribution to journal › Comment/debate › Research › peer-review
  2 Citations (Scopus)

• Elevated genetic risk for multiple sclerosis emerged in steppe pastoralist populations

  Barrie, W., Yang, Y., Irving-Pease, E. K., Attfield, K. E., Scorrano, G., Jensen, L. T., Armen, A. P., Dimopoulos, E. A., Stern, A., Refoyo-Martinez, A., Pearson, A., Ramsøe, A., Gaunitz, C., Demeter, F., Jørkov, M. L. S., Møller, S. B., Springborg, B., Klassen, L., Hyldgård, I. M., Wickmann, N. & 11 others, Vinner, L., Korneliussen, T. S., Allentoft, M. E., Sikora, M., Kristiansen, K., Rodriguez, S., Nielsen, R., Iversen, A. K. N., Lawson, D. J., Fugger, L. & Willerslev, E., 2024, In: Nature. 625, 7994, p. 321-328

  Research output: Contribution to journal › Journal article › Research › peer-review

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  34 Citations (Scopus)

  45 Downloads (Pure)

• The selection landscape and genetic legacy of ancient Eurasians

  Irving-Pease, E. K., Refoyo-Martínez, A., Barrie, W., Ingason, A., Pearson, A., Fischer, A., Sjögren, K. G., Halgren, A. S., Macleod, R., Demeter, F., Henriksen, R. A., Vimala, T., McColl, H., Vaughn, A. H., Speidel, L., Stern, A. J., Scorrano, G., Ramsøe, A., Schork, A. J., Rosengren, A. & 14 others, Zhao, L., Kristiansen, K., Iversen, A. K. N., Fugger, L., Sudmant, P. H., Lawson, D. J., Durbin, R., Korneliussen, T., Werge, T., Allentoft, M. E., Sikora, M., Nielsen, R., Racimo, F. & Willerslev, E., 2024, In: Nature. 625, 7994, p. 312-320 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

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  21 Citations (Scopus)

  6 Downloads (Pure)
• 2022

  Epitope length variants balance protective immune responses and viral escape in HIV-1 infection

  Pymm, P., Tenzer, S., Wee, E., Weimershaus, M., Burgevin, A., Kollnberger, S., Gerstoft, J., Josephs, T. M., Ladell, K., McLaren, J. E., Appay, V., Price, D. A., Fugger, L., Bell, J. I., Schild, H., van Endert, P., Harkiolaki, M. & Iversen, A. K. N., 2022, In: Cell Reports. 38, 9, 22 p., 110449.

  Research output: Contribution to journal › Journal article › Research › peer-review

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  2 Citations (Scopus)

  14 Downloads (Pure)

• Identification of early neurodegenerative pathways in progressive multiple sclerosis

  Kaufmann, M., Schaupp, A. L., Sun, R., Coscia, F., Dendrou, C. A., Cortes, A., Kaur, G., Evans, H. G., Mollbrink, A., Navarro, J. F., Sonner, J. K., Mayer, C., DeLuca, G. C., Lundeberg, J., Matthews, P. M., Attfield, K. E., Friese, M. A., Mann, M. & Fugger, L., 2022, In: Nature Neuroscience. 25, p. 944-955

  Research output: Contribution to journal › Journal article › Research › peer-review

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  59 Citations (Scopus)

  16 Downloads (Pure)

• Ingested non-essential amino acids recruit brain orexin cells to suppress eating in mice

  Viskaitis, P., Arnold, M., Garau, C., Jensen, L. T., Fugger, L., Peleg-Raibstein, D. & Burdakov, D., 2022, In: Current biology : CB. 32, 8, p. 1812-1821 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  20 Citations (Scopus)

• MOG antibody-associated disease after vaccination with ChAdOx1 nCoV-19

  Francis, A., Palace, J. & Fugger, L., 2022, In: The Lancet Neurology. 21, 3, p. 217-218 2 p.

  Research output: Contribution to journal › Comment/debate › Research
  17 Citations (Scopus)

• Mouse fetal growth restriction through parental and fetal immune gene variation and intercellular communications cascade

  Kaur, G., Porter, C. B. M., Ashenberg, O., Lee, J., Riesenfeld, S. J., Hofree, M., Aggelakopoulou, M., Subramanian, A., Kuttikkatte, S. B., Attfield, K. E., Desel, C. A. E., Davies, J. L., Evans, H. G., Avraham-Davidi, I., Nguyen, L. T., Dionne, D. A., Neumann, A. E., Jensen, L. T., Barber, T. R., Soilleux, E. & 5 others, Carrington, M., McVean, G., Rozenblatt-Rosen, O., Regev, A. & Fugger, L., 2022, In: Nature Communications. 13, 4398.

  Research output: Contribution to journal › Journal article › Research › peer-review

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  10 Citations (Scopus)

  10 Downloads (Pure)

• The immunology of multiple sclerosis

  Attfield, K. E., Jensen, L. T., Kaufmann, M., Friese, M. A. & Fugger, L., 2022, In: Nature Reviews Immunology. 22, 12, p. 734-750 17 p.

  Research output: Contribution to journal › Review › Research › peer-review
  165 Citations (Scopus)
• 2020

  A novel neurodegenerative spectrum disorder in patients with MLKL deficiency

  Faergeman, S. L., Evans, H., Attfield, K. E., Desel, C., Kuttikkatte, S. B., Sommerlund, M., Jensen, L. T., Frokiaer, J., Friese, M. A., Matthews, P. M., Luchtenborg, C., Brügger, B., Oturai, A. B., Dendrou, C. A. & Fugger, L., 2020, In: Cell Death and Disease. 11, 5, 303.

  Research output: Contribution to journal › Journal article › Research › peer-review

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  19 Citations (Scopus)

  21 Downloads (Pure)

• Identifying cross-disease components of genetic risk across hospital data in the UK Biobank

  Cortes, A., Albers, P. K., Dendrou, C. A., Fugger, L. & McVean, G., 2020, In: Nature Genetics. 52, 1, p. 126-134 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

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  26 Citations (Scopus)

  11 Downloads (Pure)
• 2017

  Bayesian analysis of genetic association across tree-structured routine healthcare data in the UK Biobank

  Cortes, A., Dendrou, C. A., Motyer, A., Jostins, L., Vukcevic, D., Dilthey, A., Donnelly, P., Leslie, S., Fugger, L. & McVean, G., 2017, In: Nature Genetics. 49, 9, p. 1311-1318 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access
  43 Citations (Scopus)
• 2015

  Factors influencing success of clinical genome sequencing across a broad spectrum of disorders

  Taylor, J. C., Martin, H. C., Lise, S., Broxholme, J., Cazier, J-B., Rimmer, A., Kanapin, A., Lunter, G., Fiddy, S., Allan, C., Aricescu, A. R., Attar, M., Babbs, C., Becq, J., Beeson, D., Bento, C., Bignell, P., Blair, E., Buckle, V. J., Bull, K. & 90 others, Cais, O., Cario, H., Chapel, H., Copley, R. R., Cornall, R., Craft, J., Dahan, K., Davenport, E. E., Dendrou, C., Devuyst, O., Fenwick, A. L., Flint, J., Fugger, L., Gilbert, R. D., Goriely, A., Green, A., Greger, I. H., Grocock, R., Gruszczyk, A. V., Hastings, R., Hatton, E., Higgs, D., Hill, A., Holmes, C., Howard, M., Hughes, L., Humburg, P., Johnson, D., Karpe, F., Kingsbury, Z., Kini, U., Knight, J. C., Krohn, J., Lamble, S., Langman, C., Lonie, L., Luck, J., McCarthy, D., McGowan, S. J., McMullin, M. F., Miller, K. A., Murray, L., Németh, A. H., Nesbit, M. A., Nutt, D., Ormondroyd, E., Oturai, A. B., Pagnamenta, A., Patel, S. Y., Percy, M., Petousi, N., Piazza, P., Piret, S. E., Polanco-Echeverry, G., Popitsch, N., Powrie, F., Pugh, C., Quek, L., Robbins, P. A., Robson, K., Russo, A., Sahgal, N., van Schouwenburg, P. A., Schuh, A., Silverman, E., Simmons, A., Sørensen, P. S., Sweeney, E., Taylor, J., Thakker, R. V., Tomlinson, I., Trebes, A., Twigg, S. R. F., Uhlig, H. H., Vyas, P., Vyse, T., Wall, S. A., Watkins, H., Whyte, M. P., Witty, L., Wright, B., Yau, C., Buck, D., Humphray, S., Ratcliffe, P. J., Bell, J. I., Wilkie, A. O. M., Bentley, D., Donnelly, P. & McVean, G., Jul 2015, In: Nature Genetics. 47, 7, p. 717-26 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  284 Citations (Scopus)
• 2014

  HIV-1 Adaptation to Antigen Processing Results in Population-Level Immune Evasion and Affects Subtype Diversification

  Tenzer, S., Crawford, H., Pymm, P., Gifford, R., Sreenu, V. B., Weimershaus, M., de Oliveira, T., Burgevin, A., Gerstoft, J., Akkad, N., Lunn, D., Fugger, L., Bell, J., Schild, H., van Endert, P. & Iversen, A. K. N., 24 Apr 2014, In: Cell Reports. 7, 2, p. 448-463 16 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  15 Citations (Scopus)
• 2012

  Use of calcium channel blockers and Parkinson's disease

  Pasternak, B., Svanström, H., Nielsen, N. M., Fugger, L., Melbye, M. & Hviid, A., 1 Apr 2012, In: American Journal of Epidemiology. 175, 7, p. 627-635 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access
  126 Citations (Scopus)
• 2004

  Efficient purification of unique antibodies using peptide affinity-matrix columns

  Jensen, L. B., Riise, E., Nielsen, L. K., Dziegiel, M. H., Fugger, L. & Engberg, J., Jan 2004, In: Journal of Immunological Methods. 284, 1-2, p. 45-54 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  12 Citations (Scopus)